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NO983678L - Nye cefemforbindelser og farmas°ytiske anvendelser derav - Google Patents

Nye cefemforbindelser og farmas°ytiske anvendelser derav

Info

Publication number
NO983678L
NO983678L NO983678A NO983678A NO983678L NO 983678 L NO983678 L NO 983678L NO 983678 A NO983678 A NO 983678A NO 983678 A NO983678 A NO 983678A NO 983678 L NO983678 L NO 983678L
Authority
NO
Norway
Prior art keywords
new
pharmaceutical applications
cephemic
compounds
helicobacter pylori
Prior art date
Application number
NO983678A
Other languages
English (en)
Other versions
NO983678D0 (no
Inventor
Yoshiki Yoshida
Shinya Okuda
Hiroshi Sasaki
Keiji Matsuda
Hisashi Takasugi
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of NO983678L publication Critical patent/NO983678L/no
Publication of NO983678D0 publication Critical patent/NO983678D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/59—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Foreliggende oppfinnelse angår nye cefem-forbindelser representert ved den følgende generelle formel (I): hvor hvert symbol er som definert i beskrivelsen, eller et salt derav, som har antimikrobiell aktivitet mot Helicobacter pylori og som er nyttige som anti-Helicobacter pylori-midler, anti-gastritt-midler, anti-ulcer-midler og anti-kreft-midler.
NO983678A 1996-02-12 1998-08-11 Nye cefemforbindelser og farmasöytiske anvendelser derav NO983678D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPN8011A AUPN801196A0 (en) 1996-02-12 1996-02-12 New cephem compounds and pharmaceutical use thereof
PCT/JP1997/000280 WO1997029111A1 (en) 1996-02-12 1997-02-05 New cephem compounds and pharmaceutical use thereof

Publications (2)

Publication Number Publication Date
NO983678L true NO983678L (no) 1998-08-11
NO983678D0 NO983678D0 (no) 1998-08-11

Family

ID=3792326

Family Applications (1)

Application Number Title Priority Date Filing Date
NO983678A NO983678D0 (no) 1996-02-12 1998-08-11 Nye cefemforbindelser og farmasöytiske anvendelser derav

Country Status (12)

Country Link
US (1) US6150351A (no)
EP (1) EP0882052A1 (no)
JP (1) JP2000505432A (no)
KR (1) KR19990082487A (no)
CN (1) CN1210539A (no)
AU (1) AUPN801196A0 (no)
EA (1) EA199800715A1 (no)
IL (1) IL125284A0 (no)
NO (1) NO983678D0 (no)
TR (1) TR199801552T2 (no)
WO (1) WO1997029111A1 (no)
ZA (1) ZA971132B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6262096B1 (en) 1997-11-12 2001-07-17 Bristol-Myers Squibb Company Aminothiazole inhibitors of cyclin dependent kinases
US6362009B1 (en) 1997-11-21 2002-03-26 Merck & Co., Inc. Solid phase synthesis of heterocycles
JPH11279180A (ja) * 1998-01-23 1999-10-12 Toyama Chem Co Ltd 新規なセファロスポリン誘導体またはその塩並びにそれらを含有する抗菌剤
US6214852B1 (en) 1998-10-21 2001-04-10 Bristol-Myers Squibb Company N-[5-[[[5-alkyl-2-oxazolyl]methyl]thio]-2-thiazolyl]-carboxamide inhibitors of cyclin dependent kinases
US6414156B2 (en) 1998-10-21 2002-07-02 Bristol-Myers Squibb Company Process for preparing azacycloalkanoylaminothiazoles
US6515004B1 (en) 1999-12-15 2003-02-04 Bristol-Myers Squibb Company N-[5-[[[5-alkyl-2-oxazolyl]methyl]thio]-2-thiazolyl]-carboxamide inhibitors of cyclin dependent kinases
US6392053B2 (en) 1999-12-15 2002-05-21 Bristol-Myers Squibb Company Process for preparing arylacetylaminothiazoles
EP1294730A4 (en) * 2000-06-28 2004-01-14 Lg Chem Investment Ltd NEW CEPHALOSPORINE COMPOUNDS AND A METHOD FOR PRODUCING THE SAME
JP2004502778A (ja) * 2000-07-07 2004-01-29 エルジー・ライフ・サイエンシーズ・リミテッド 新規なセファロスポリン化合物およびその製造方法
CA2461577A1 (en) * 2001-11-12 2003-05-22 Hans Rudolf Pfaendler Novel c-3 s/o- and s/n formaldehe acetal derivatives of cephalosporins and their use as antibiotics
CN103626715B (zh) * 2012-08-22 2017-12-22 帝斯曼知识产权资产管理有限公司 一种合成维生素b1中间体的方法
CN108066345A (zh) * 2016-11-14 2018-05-25 武汉华杰世纪生物医药有限公司 一种具有抗肿瘤作用的化合物
CN110327349B (zh) * 2019-07-10 2021-12-28 昆明医科大学 头孢类抗生素作为制备抗癌药物的应用及其抗癌药物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH605997A5 (no) * 1974-08-30 1978-10-13 Ciba Geigy Ag
US3992377A (en) * 1974-12-13 1976-11-16 Eli Lilly And Company 3-Thio-substituted cephalosporin antibiotics
EP0009008A3 (de) * 1978-09-08 1980-05-14 Ciba-Geigy Ag Cephalosporinderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
FR2550200B1 (fr) * 1983-08-01 1988-04-08 Fujisawa Pharmaceutical Co Procede de preparation de composes de cephem a activite antimicrobienne et nouveaux produits ainsi obtenus
JPH02134385A (ja) * 1988-11-14 1990-05-23 Taisho Pharmaceut Co Ltd セファロスポリン誘導体
JP3195371B2 (ja) * 1991-03-11 2001-08-06 大塚化学株式会社 セフエム誘導体の製造法
US5162521A (en) * 1991-06-06 1992-11-10 Bristol-Myers Squibb Company Processes for making cephems from allenylazetidinone derivatives
PL316633A1 (en) * 1994-04-01 1997-02-03 Microcide Pharmaceuticals Cephalosporin antibiotics
JPH08151386A (ja) * 1994-09-27 1996-06-11 Takeda Chem Ind Ltd 複素環エチルチオセフェム化合物、その製造法および抗菌組成物
EP0796263A1 (en) * 1994-12-09 1997-09-24 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds and pharmaceutical use thereof

Also Published As

Publication number Publication date
CN1210539A (zh) 1999-03-10
AUPN801196A0 (en) 1996-03-07
EA199800715A1 (ru) 1999-02-25
US6150351A (en) 2000-11-21
JP2000505432A (ja) 2000-05-09
KR19990082487A (ko) 1999-11-25
EP0882052A1 (en) 1998-12-09
IL125284A0 (en) 1999-03-12
WO1997029111A1 (en) 1997-08-14
TR199801552T2 (xx) 1998-11-23
NO983678D0 (no) 1998-08-11
ZA971132B (en) 1997-09-03

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