NO942468D0 - Fremgangsmåte for fremstilling av 2-alkyl-3,4,6-trifluorbenzoesyre - Google Patents
Fremgangsmåte for fremstilling av 2-alkyl-3,4,6-trifluorbenzoesyreInfo
- Publication number
- NO942468D0 NO942468D0 NO942468A NO942468A NO942468D0 NO 942468 D0 NO942468 D0 NO 942468D0 NO 942468 A NO942468 A NO 942468A NO 942468 A NO942468 A NO 942468A NO 942468 D0 NO942468 D0 NO 942468D0
- Authority
- NO
- Norway
- Prior art keywords
- alkyl
- preparation
- trifluorobenzoic acid
- manufacture
- antibacterial agents
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- LOAUVZALPPNFOQ-UHFFFAOYSA-N quinaldic acid Chemical class C1=CC=CC2=NC(C(=O)O)=CC=C21 LOAUVZALPPNFOQ-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Quinoline Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14746288A | 1988-01-25 | 1988-01-25 | |
US07/280,924 US4920120A (en) | 1988-01-25 | 1988-12-09 | Antibacterial agents |
PCT/US1989/000278 WO1989006649A2 (en) | 1988-01-25 | 1989-01-23 | Antibacterial agents |
Publications (3)
Publication Number | Publication Date |
---|---|
NO942468L NO942468L (no) | 1990-07-24 |
NO942468D0 true NO942468D0 (no) | 1994-06-30 |
NO300263B1 NO300263B1 (no) | 1997-05-05 |
Family
ID=26844956
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO903286A NO178194C (no) | 1988-01-25 | 1990-07-24 | Analogifremgangsmåte for fremstilling av terapeutisk aktive naftyridin-derivater |
NO942468A NO300263B1 (no) | 1988-01-25 | 1994-06-30 | Fremgangsmåte for fremstilling av 2-alkyl-3,4,6-trifluorbenzoesyre |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO903286A NO178194C (no) | 1988-01-25 | 1990-07-24 | Analogifremgangsmåte for fremstilling av terapeutisk aktive naftyridin-derivater |
Country Status (16)
Country | Link |
---|---|
US (1) | US4920120A (no) |
EP (2) | EP0326891B1 (no) |
JP (2) | JP2815119B2 (no) |
KR (3) | KR0130931B1 (no) |
AT (1) | ATE109471T1 (no) |
AU (4) | AU624118B2 (no) |
CA (1) | CA1340492C (no) |
DE (1) | DE68917163T2 (no) |
DK (2) | DK173057B1 (no) |
ES (1) | ES2056963T3 (no) |
FI (1) | FI93360C (no) |
IE (1) | IE65350B1 (no) |
NO (2) | NO178194C (no) |
NZ (1) | NZ227680A (no) |
PT (1) | PT89520B (no) |
WO (1) | WO1989006649A2 (no) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3685157D1 (de) * | 1985-06-26 | 1992-06-11 | Daiichi Seiyaku Co | Pyridoncarbonsaeurederivate. |
ATE58538T1 (de) * | 1986-07-04 | 1990-12-15 | Chemie Linz Gmbh | 4-chinolon-3-carbonsaeurederivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate. |
US5591744A (en) * | 1987-04-16 | 1997-01-07 | Otsuka Pharmaceutical Company, Limited | Benzoheterocyclic compounds |
US5290934A (en) * | 1987-04-16 | 1994-03-01 | Otsuka Pharmaceutical Company, Limited | Benzoheterocyclic compounds |
US5585491A (en) * | 1988-01-25 | 1996-12-17 | Otsuka Pharmaceutical Co., Ltd. | Antibacterial agents |
US5173484A (en) * | 1988-02-05 | 1992-12-22 | Bayer Aktiengesellschaft | Quinolone- and naphthyridone carboxylic acid derivatives, process for their production, antibacterial compositions and feed additives containing them |
US5147873A (en) * | 1988-08-23 | 1992-09-15 | Pfizer Inc. | Amino-substituted bridged azabicyclic quinolone carboxylic acids and esters |
US5057523A (en) * | 1988-09-22 | 1991-10-15 | Abbott Laboratories | Dipeptide quinolone derivatives |
US5262417A (en) * | 1988-12-06 | 1993-11-16 | The Upjohn Company | Antibacterial quinolone compounds |
AU5123690A (en) * | 1989-03-13 | 1990-09-13 | Bristol-Myers Squibb Company | 5-substituted-1,4-dihydro-4-oxo-nephthyridine-3-carboxylate antibacterial agents |
US5140033A (en) * | 1989-04-03 | 1992-08-18 | Bayer Aktiengesellschaft | Antibacterial 5-alkylquinolonecarboxylic acids |
DE3910663A1 (de) * | 1989-04-03 | 1990-10-04 | Bayer Ag | 5-alkylchinoloncarbonsaeuren |
DE3934082A1 (de) * | 1989-10-12 | 1991-04-18 | Bayer Ag | Chinoloncarbonsaeurederivate, verfahren zu ihrer herstellung sowie ihre verwendung als antivirale mittel |
CA2030217A1 (en) * | 1989-11-21 | 1991-05-22 | Jun Imose | Pyridone-carboxylic acid derivatives useful as veterinary medicines |
DE4019023A1 (de) * | 1990-06-14 | 1991-12-19 | Bayer Ag | Verfahren zur herstellung von chinolincarbonsaeuren |
US5258528A (en) * | 1990-11-30 | 1993-11-02 | Warner-Lambert Company | Individual stereoisomers of pyrrolidine methanamines substituted on the ring nitrogen by a 1-phenylethyl group |
DE69231422T2 (de) * | 1991-05-28 | 2001-03-29 | Daiichi Pharmaceutical Co., Ltd. | Pyridoncarbonsäurederivate |
EP0544981A3 (en) * | 1991-11-25 | 1993-07-14 | Warner-Lambert Company | Naphthyridone carboxylic acid derivatives and antibacterial compositions containing them |
DE4408212A1 (de) * | 1994-03-11 | 1995-09-14 | Bayer Ag | 5-Vinyl- und 5-Ethinyl-chinolon- und -naphthyridon-carbonsäuren |
DK0688772T3 (da) * | 1994-06-16 | 1999-11-01 | Lg Chemical Ltd | Quinolincarboxylsyrederivater med 7-(4-aminomethyl-3-oxim)-pyrrolidinsubstituenter og fremgangsmåde til deres fremstilling |
WO1996002512A1 (fr) * | 1994-07-18 | 1996-02-01 | Ube Industries, Ltd. | Acide du type trifluoromethylquinoleinecarboxylique |
AU3154095A (en) * | 1994-08-02 | 1996-03-04 | Procter & Gamble Company, The | Process for making quinolonyl lactam antimicrobials and novel intermediate compounds |
KR100242355B1 (ko) * | 1994-08-02 | 2000-03-02 | 데이비드 엠 모이어 | 항미생물 화합물의 제조 방법 |
ATE289999T1 (de) | 1996-07-12 | 2005-03-15 | Daiichi Seiyaku Co | Cis-substituierte aminocyclopropanderivate |
MA24500A1 (fr) | 1997-03-21 | 1998-10-01 | Lg Life Sciences Ltd | Derive du sel d'acide carboxylique de naphthyridine . |
US20020032216A1 (en) | 1997-03-21 | 2002-03-14 | Lg Chemical Ltd. | Salt of naphthyridine carboxylic acid derivative |
MY138335A (en) | 1997-09-15 | 2009-05-29 | Procter & Gamble | Antimicrobial quinolones, their compositions and uses |
US6387928B1 (en) | 1997-09-15 | 2002-05-14 | The Procter & Gamble Co. | Antimicrobial quinolones, their compositions and uses |
ATE284684T1 (de) | 1997-10-27 | 2005-01-15 | Sumitomo Pharma | Amidderivate zur behandlung neurodegenerativer erkrankungen der netzhaut |
DE69936350T2 (de) * | 1998-09-14 | 2008-02-28 | Otsuka Pharmaceutical Co., Ltd. | Verfahren zur herstellung fluorierter benzoesäuren |
US6395746B1 (en) | 1998-09-30 | 2002-05-28 | Alcon Manufacturing, Ltd. | Methods of treating ophthalmic, otic and nasal infections and attendant inflammation |
US6716830B2 (en) * | 1998-09-30 | 2004-04-06 | Alcon, Inc. | Ophthalmic antibiotic compositions containing moxifloxacin |
US6509327B1 (en) | 1998-09-30 | 2003-01-21 | Alcon Manufacturing, Ltd. | Compositions and methods for treating otic, ophthalmic and nasal infections |
DE19850788A1 (de) * | 1998-11-04 | 2000-05-11 | Clariant Gmbh | Verfahren zur Herstellung von Trifluorbenzoesäuren |
IL143210A0 (en) * | 1998-11-24 | 2002-04-21 | Daiichi Seiyaku Co | Cycloalkyl-substituted aminomethylpyrrolidine derivatives |
US6762181B1 (en) | 1999-03-10 | 2004-07-13 | Daiichi Pharmaceutical Co., Ltd. | Aminomethylpyrrolidine derivatives having aromatic substituents |
GB9920917D0 (en) | 1999-09-03 | 1999-11-10 | Sb Pharmco Inc | Novel process |
GB9920919D0 (en) | 1999-09-03 | 1999-11-10 | Sb Pharmco Inc | Novel compound |
KR100517638B1 (ko) | 2002-04-08 | 2005-09-28 | 주식회사 엘지생명과학 | 게미플록사신 산염의 새로운 제조방법 |
EP1564210B9 (en) * | 2002-11-20 | 2010-03-31 | Japan Tobacco Inc. | 4-oxoquinoline compounds and utilization thereof as hiv integrase inhibitors |
SG144936A1 (en) * | 2003-09-10 | 2008-08-28 | Kyorin Seiyaku Kk | 7-(4-substituted-3-cyclopropylaminomethyl-1- pyrrolidinyl)quinolonecarboxylic acid derivative |
KR100981351B1 (ko) | 2003-10-29 | 2010-09-10 | 주식회사 엘지생명과학 | 7-클로로-1-사이클로프로필-6-플루오로-4-옥소-1,4-디하이드로-1,8-나프티리딘-3-카복실산의 제조방법 |
NZ570706A (en) | 2006-03-06 | 2010-08-27 | Japan Tobacco Inc | Methods for producing an 4-oxoquinoline compound |
IN2014CN00532A (no) | 2006-03-06 | 2015-04-03 | Japan Tobacco Inc | |
BRPI0709772B8 (pt) * | 2006-03-28 | 2021-05-25 | The Protecter & Gamble Company | sais de malato e polimorfos do ácido (3s,5s)-7-[3-amino-5-metil-piperidinil]-1-ciclopropil-1,4-diidro-8-metóxi-4-oxo-3-quinolinocarboxílico |
MX2008012488A (es) * | 2006-03-28 | 2008-10-10 | Procter & Gamble | Un proceso de acoplamiento para preparar intermedios de quinolona. |
CA2647457C (en) * | 2006-03-28 | 2011-05-24 | The Procter & Gamble Company | A hydride reduction process for preparing quinolone intermediates |
EP2149571A4 (en) * | 2007-05-24 | 2010-09-01 | Kyorin Seiyaku Kk | MUTILINE DERIVATIVE WITH A RINGED, HETEROCYCLIC AND AROMATIC CARBOXYLIC ACID STRUCTURE IN A SUBSTITUTE AT POSITION 14 |
CN111620806B (zh) * | 2020-06-12 | 2021-05-11 | 常州瑞明药业有限公司 | 一种氨氯地平中间体的制备方法 |
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GB1208279A (en) * | 1967-05-12 | 1970-10-14 | Ici Ltd | Veterinary compositions containing 4-hydroxy-1,8-naphthyridine derivatives |
US3753993A (en) | 1971-05-17 | 1973-08-21 | Sterling Drug Inc | 1,4-dihydro-4-oxo-7-pyridyl-3-quinoline-carboxylic acid derivatives |
US3907808A (en) | 1971-05-17 | 1975-09-23 | Sterling Drug Inc | 1,4-Dihydro-4-oxo-7-pyridyl-3-quinolinecarboxylic acid derivatives |
JPS53141286A (en) * | 1977-05-16 | 1978-12-08 | Kyorin Seiyaku Kk | Novel substituted quinolinecarboxylic acid |
JPS5845426B2 (ja) * | 1978-09-29 | 1983-10-08 | 杏林製薬株式会社 | 置換キノリンカルボン酸誘導体 |
JPS5649382A (en) * | 1979-09-28 | 1981-05-02 | Dainippon Pharmaceut Co Ltd | 6-fluoro-7-cyclic amino-1,8-naphthylidine derivative and its salt |
JPS58150543A (ja) | 1982-03-04 | 1983-09-07 | Chisso Corp | 2,4,5−トリフルオロ安息香酸トランス−4−(トランス−4′−アルキルシクロヘキシル)シクロヘキシルエステル |
US4469885A (en) * | 1983-05-09 | 1984-09-04 | G. D. Searle & Co. | Halogenated protease inhibitors |
CS274601B2 (en) * | 1983-07-27 | 1991-09-15 | Dainippon Pharmaceutical Co | Method of 1,8-naphthyridine derivative production |
US4774246A (en) | 1984-01-26 | 1988-09-27 | Abbott Laboratories | Quinoline antibacterial compounds |
US4571396A (en) * | 1984-04-16 | 1986-02-18 | Warner-Lambert Company | Antibacterial agents |
JPS6185349A (ja) * | 1984-10-04 | 1986-04-30 | Nippon Shokubai Kagaku Kogyo Co Ltd | 2,3,4,5−テトラフルオロ安息香酸の製法 |
US4663457A (en) | 1985-01-23 | 1987-05-05 | Warner-Lambert Company | 1-cyclopropyl-6,7-dihalo-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid and their esters, useful as intermediates for preparing the 7-amine substituted naphthyridines |
AT392789B (de) * | 1985-01-23 | 1991-06-10 | Toyama Chemical Co Ltd | Verfahren zur herstellung von 1-substituierten aryl-1,4-dihydro-4-oxonaphthyridinderivaten |
JPS6245A (ja) * | 1985-03-13 | 1987-01-06 | Nippon Shokubai Kagaku Kogyo Co Ltd | 2,3,4,5−テトラフルオロ安息香酸の製法 |
US4684648A (en) * | 1985-05-10 | 1987-08-04 | Otsuka Pharmaceutical Company Limited | Antimicrobial 1-substituted phenyl-4-oxoquinoline-3-carboxylic acid compounds and compositions thereof |
DE3522406A1 (de) | 1985-06-22 | 1987-01-02 | Bayer Ag | Verfahren zur herstellung von 1,8-verbrueckten 4-chinolon-3-carbonsaeuren |
DE3685157D1 (de) * | 1985-06-26 | 1992-06-11 | Daiichi Seiyaku Co | Pyridoncarbonsaeurederivate. |
US4772706A (en) * | 1986-01-13 | 1988-09-20 | Warner-Lambert Company | Process for quinoline-3-carboxylic acid antibacterial agents |
DE3600891A1 (de) | 1986-01-15 | 1987-07-16 | Bayer Ag | 1,8-verbrueckte 4-chinolon-3-carbonsaeuren und diese enthaltende arzneimittel |
EP0242789A3 (en) * | 1986-04-25 | 1990-09-05 | Dainippon Pharmaceutical Co., Ltd. | Novel quinoline derivates and processes for preparation thereof |
US5591744A (en) * | 1987-04-16 | 1997-01-07 | Otsuka Pharmaceutical Company, Limited | Benzoheterocyclic compounds |
NO885426L (no) * | 1987-12-11 | 1989-06-12 | Dainippon Pharmaceutical Co | Kinolinderivater, samt fremgangsmaate ved fremstilling derav. |
AU5123690A (en) * | 1989-03-13 | 1990-09-13 | Bristol-Myers Squibb Company | 5-substituted-1,4-dihydro-4-oxo-nephthyridine-3-carboxylate antibacterial agents |
DE3910663A1 (de) * | 1989-04-03 | 1990-10-04 | Bayer Ag | 5-alkylchinoloncarbonsaeuren |
JP2946980B2 (ja) * | 1992-12-18 | 1999-09-13 | トヨタ自動車株式会社 | 内燃機関の排気浄化装置 |
JPH06200045A (ja) * | 1993-01-05 | 1994-07-19 | Sumitomo Electric Ind Ltd | 制振材及びその製造方法 |
-
1988
- 1988-12-09 US US07/280,924 patent/US4920120A/en not_active Expired - Lifetime
- 1988-12-30 IE IE390088A patent/IE65350B1/en not_active IP Right Cessation
-
1989
- 1989-01-03 CA CA000587421A patent/CA1340492C/en not_active Expired - Fee Related
- 1989-01-20 NZ NZ227680A patent/NZ227680A/xx unknown
- 1989-01-23 EP EP89101085A patent/EP0326891B1/en not_active Expired - Lifetime
- 1989-01-23 DE DE68917163T patent/DE68917163T2/de not_active Expired - Fee Related
- 1989-01-23 ES ES89101085T patent/ES2056963T3/es not_active Expired - Lifetime
- 1989-01-23 JP JP1502150A patent/JP2815119B2/ja not_active Expired - Fee Related
- 1989-01-23 AT AT89101085T patent/ATE109471T1/de not_active IP Right Cessation
- 1989-01-23 KR KR1019890701774A patent/KR0130931B1/ko not_active IP Right Cessation
- 1989-01-23 AU AU30483/89A patent/AU624118B2/en not_active Ceased
- 1989-01-23 EP EP89902326A patent/EP0398967A1/en active Pending
- 1989-01-23 WO PCT/US1989/000278 patent/WO1989006649A2/en active IP Right Grant
- 1989-01-24 PT PT89520A patent/PT89520B/pt not_active IP Right Cessation
-
1990
- 1990-07-20 DK DK199001746A patent/DK173057B1/da not_active IP Right Cessation
- 1990-07-23 FI FI903696A patent/FI93360C/fi not_active IP Right Cessation
- 1990-07-24 NO NO903286A patent/NO178194C/no not_active IP Right Cessation
-
1992
- 1992-03-27 AU AU13888/92A patent/AU659444B2/en not_active Ceased
-
1994
- 1994-06-30 NO NO942468A patent/NO300263B1/no not_active IP Right Cessation
-
1995
- 1995-07-27 AU AU27224/95A patent/AU671575B2/en not_active Ceased
- 1995-07-27 AU AU27223/95A patent/AU674272B2/en not_active Ceased
-
1996
- 1996-12-09 DK DK140996A patent/DK140996A/da not_active Application Discontinuation
-
1997
- 1997-09-18 KR KR1019970706494A patent/KR0182275B1/ko not_active IP Right Cessation
- 1997-09-18 KR KR97706493A patent/KR0145958B1/ko not_active Application Discontinuation
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1998
- 1998-04-01 JP JP10104208A patent/JP2986154B2/ja not_active Expired - Fee Related
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