[go: up one dir, main page]

NO931186L - THERAPEUTIC ACTIVE IMIDAZOLD DERIVATIVES, PROCEDURE FOR THEIR PREPARATION AND USE OF THEREOF - Google Patents

THERAPEUTIC ACTIVE IMIDAZOLD DERIVATIVES, PROCEDURE FOR THEIR PREPARATION AND USE OF THEREOF

Info

Publication number
NO931186L
NO931186L NO93931186A NO931186A NO931186L NO 931186 L NO931186 L NO 931186L NO 93931186 A NO93931186 A NO 93931186A NO 931186 A NO931186 A NO 931186A NO 931186 L NO931186 L NO 931186L
Authority
NO
Norway
Prior art keywords
procedure
preparation
therapeutic active
imidazold
derivatives
Prior art date
Application number
NO93931186A
Other languages
Norwegian (no)
Other versions
NO931186D0 (en
Inventor
Pierre Dodey
Michel Bondoux
Patrice Renaut
Patrice Pruneau
Original Assignee
Fournier Ind & Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fournier Ind & Sante filed Critical Fournier Ind & Sante
Publication of NO931186D0 publication Critical patent/NO931186D0/en
Publication of NO931186L publication Critical patent/NO931186L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/62—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with triarylmethyl radicals attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/68—Halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO93931186A 1992-04-01 1993-03-30 THERAPEUTIC ACTIVE IMIDAZOLD DERIVATIVES, PROCEDURE FOR THEIR PREPARATION AND USE OF THEREOF NO931186L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR929203944A FR2689508B1 (en) 1992-04-01 1992-04-01 IMIDAZOLE DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR THERAPEUTIC APPLICATION.

Publications (2)

Publication Number Publication Date
NO931186D0 NO931186D0 (en) 1993-03-30
NO931186L true NO931186L (en) 1993-10-04

Family

ID=9428340

Family Applications (1)

Application Number Title Priority Date Filing Date
NO93931186A NO931186L (en) 1992-04-01 1993-03-30 THERAPEUTIC ACTIVE IMIDAZOLD DERIVATIVES, PROCEDURE FOR THEIR PREPARATION AND USE OF THEREOF

Country Status (13)

Country Link
EP (1) EP0564356A1 (en)
JP (1) JPH06263743A (en)
KR (1) KR930021622A (en)
CN (1) CN1081438A (en)
AU (1) AU3554693A (en)
CA (1) CA2092852A1 (en)
FI (1) FI931414L (en)
FR (1) FR2689508B1 (en)
HU (1) HUT64752A (en)
MX (1) MX9301882A (en)
NO (1) NO931186L (en)
TW (1) TW232012B (en)
ZA (1) ZA932351B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6015817A (en) * 1996-12-05 2000-01-18 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
UA71587C2 (en) 1998-11-10 2004-12-15 Шерінг Акцієнгезелльшафт Anthranilic acid amides and use thereof as medicaments
DE10023486C1 (en) * 2000-05-09 2002-03-14 Schering Ag Ortho substituted anthranilic acid amides and their use as medicines
CA2453396A1 (en) * 2001-07-11 2003-01-23 Yale University Compounds and methods for the inhibition of trypanosoma cruzi
US7615565B2 (en) 2002-07-31 2009-11-10 Bayer Schering Pharma Aktiengesellschaft VEGFR-2 and VEGFR-3 inhibitory anthranilamide pyridines
UA89035C2 (en) 2003-12-03 2009-12-25 Лео Фарма А/С Hydroxamic acid esters and pharmaceutical use thereof
US7906533B2 (en) 2004-11-03 2011-03-15 Bayer Schering Pharma Ag Nicotinamide pyridinureas as vascular endothelial growth factor (VEGF) receptor kinase inhibitors
EP1655295A1 (en) 2004-11-03 2006-05-10 Schering Aktiengesellschaft Anthranilamide pyridinureas as VEGF receptor kinase inhibitors
EP1657241A1 (en) 2004-11-03 2006-05-17 Schering Aktiengesellschaft Novel anthranilamide pyridinureas as VEGF receptor kinase inhibitors
EP1752450A1 (en) 2005-08-01 2007-02-14 Merck Sante Imidazole derivatives as fructose-1,6-bisphosphatase inhibitors and pharmaceutical compositions containing them
US8563586B2 (en) 2007-05-24 2013-10-22 Eldrug S.A. 1,(3,)5-substituted imidazoles, their use in the treatment of hypertension and methods for their preparation
US20100216854A1 (en) * 2007-08-01 2010-08-26 Eldrug S.A. 1,3 and 1,3,5 substituted imidazoles as antihypertensives
GR1006917B (en) * 2007-10-24 2010-07-30 Ελληνικα Φαρμακα Ερευνα Και Αναπτυξη Eldrug Α.Ε., Angiotensin ii receptor antagonists based on histamin with sympathetic suppressant properties ans synthetic methods in the treatment of hypertension and cardiovascular diseases
RU2522444C2 (en) 2008-08-27 2014-07-10 Лео Фарма А/С Pyridine derivatives as inhibitors of vascular endothelium growth factor receptors 2 (vegfr-2) and protein tyrosine kinase
CN102584709B (en) * 2011-12-19 2016-08-17 浙江华海药业股份有限公司 A kind of preparation technology of the Eprosartan intermediate aryl imidazole aldehyde of improvement
JP7197880B2 (en) * 2017-10-19 2022-12-28 学校法人 名城大学 Esterifying agent and its use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2110663B (en) * 1981-12-04 1985-08-07 Farmos Group Ltd Imidazole derivatives
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles
CA1338238C (en) * 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
EP0403159B1 (en) * 1989-06-14 2000-03-01 Smithkline Beecham Corporation Imidazolyl-alkenoic acids
CA2018443A1 (en) * 1989-06-14 1990-12-14 Joseph A. Finkelstein Imidazolyl-alkenoic acids
CA2027937A1 (en) * 1989-10-25 1991-04-26 Richard M. Keenan Substituted 5-¬ (tetrazolyl)alkenyl|imidazoles
CA2028925A1 (en) * 1989-11-06 1991-05-07 Gerald R. Girard Substituted n-(imidazolyl)alkyl alanine derivatives
GB8927928D0 (en) * 1989-12-11 1990-02-14 Roussel Lab Ltd Chemical compounds
NZ239161A (en) * 1990-07-31 1994-01-26 Smithkline Beecham Corp Substituted [1h-imidazol-5-yl] alkanoic acid derivatives; medicaments,

Also Published As

Publication number Publication date
KR930021622A (en) 1993-11-22
AU3554693A (en) 1993-10-07
FR2689508A1 (en) 1993-10-08
FI931414L (en) 1993-10-02
HU9300942D0 (en) 1993-06-28
FR2689508B1 (en) 1994-06-17
CN1081438A (en) 1994-02-02
CA2092852A1 (en) 1993-10-02
TW232012B (en) 1994-10-11
ZA932351B (en) 1994-10-03
JPH06263743A (en) 1994-09-20
HUT64752A (en) 1994-02-28
EP0564356A1 (en) 1993-10-06
MX9301882A (en) 1994-06-30
NO931186D0 (en) 1993-03-30
FI931414A0 (en) 1993-03-29

Similar Documents

Publication Publication Date Title
DK476089D0 (en) THERAPEUTIC ACTIVE RELATIONS AND THEIR PREPARATION
NO924650D0 (en) DIALCOXY-PYRIDINYL-BENZIMIDAZOLD DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE
NO884625D0 (en) N-SUBSTITUTED DERIVATIVES OF 1-DESOXYNOJIRIMYCINE AND 1-DESOXYMANNOJIRIMYCIN, PROCEDURE FOR THEIR PREPARATION AND THEIR USE IN MEDICINE.
NO914667L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE ARYLED DERIVATIVES
NO894630L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE KINUCLIDINE DERIVATIVES.
NO943682D0 (en) Imidazol-4-yl-piperidine derivatives, their preparation and therapeutic use
NO171269C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE PROPENONOXIMERS AND INTERMEDIATES
NO922275D0 (en) ARYLETERS, THEIR PREPARATION AND PROCEDURE FOR TREATMENT
NO931186L (en) THERAPEUTIC ACTIVE IMIDAZOLD DERIVATIVES, PROCEDURE FOR THEIR PREPARATION AND USE OF THEREOF
NO165398C (en) ANALOGY PROCEDURE AND PREPARATION OF THERAPEUTIC ACTIVE NITROFURAND DERIVATIVES.
NO913843D0 (en) THERAPEUTIC ACTIVE PYRIMIDINE CARBOXAMIDE DERIVATIVES AND PROCEDURES FOR THEIR PREPARATION.
NO173060C (en) ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 2-IMINO-BENZOTIAZOLINE DERIVATIVES AND THEIR PREPARATION
NO962477L (en) Benzamide derivatives, their preparation and their therapeutic use
NO900697D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE ACETAMIDE DERIVATIVES.
NO891006D0 (en) THERAPEUTIC ACTIVE POLYPEPTID AND PROCEDURE FOR ITS PREPARATION.
NO891723D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE CHINAZOLINE DERIVATIVES.
DK0835254T3 (en) Oxazolidinone derivatives, their preparation and their therapeutic use
NO984624D0 (en) New furan-diarylmethylidene derivatives, methods of their preparation and therapeutic uses thereof
NO921563L (en) THERAPEUTIC ACTIVE AMINOPYRIMIDINE DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND USE THEREOF
NO922358D0 (en) TERT.-BUTYLPHENYL-1-AMINO-4-HYDROXYBUTANE DERIVATIVES, PROCEDURES OF THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THE COMPOUNDS
NO923249D0 (en) THERAPEUTIC ACTIVE PYRIMIDINE DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION
NO934227D0 (en) Pyrrole derivatives, methods for their preparation and therapeutic use
DK0842148T3 (en) Derivatives of benzenesulfonamide, their preparation and their therapeutic use
NO955242D0 (en) Piperidine derivatives, processes for their preparation and their therapeutic use
NO931167D0 (en) THERAPEUTIC ACTIVE SUGAR DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION