NO923452D0 - Diastereomere av 3-cefem-4-karboksylsyre-1-(isopropoksy-karbonyloksy)etylester og fremgangsmaate for fremstilling derav - Google Patents

Diastereomere av 3-cefem-4-karboksylsyre-1-(isopropoksy-karbonyloksy)etylester og fremgangsmaate for fremstilling derav

Info

Publication number: NO923452D0
Authority: NO; Norway
Prior art keywords: formula; general formula; solution; acid; carboxylic acid
Prior art date: 1991-09-07

Application number

NO923452A

Other languages

English (en)

Other versions

NO302122B1 (no

NO923452L (no

Inventor

Gerd Fischer

Elisabeth Deffossa

Uwe Gerlach

Rolf Hoerlein

Norbert Krass

Rudolf Lattrell

Ulrich Stache

Theodor Wollmann

Dieter Isert

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-09-07

Filing date

1992-09-04

Publication date

1992-09-04

1992-09-04 Application filed by Hoechst Ag filed Critical Hoechst Ag

1992-09-04 Publication of NO923452D0 publication Critical patent/NO923452D0/no

1993-03-08 Publication of NO923452L publication Critical patent/NO923452L/no

1998-01-26 Publication of NO302122B1 publication Critical patent/NO302122B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
- C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Hydrogenated Pyridines (AREA)

NO923452A 1991-09-07 1992-09-04 Rene diastereomere av 3-cefem-4-karboksylsyre-1-(isopropoksykarbonyloksy)etylester, farmasöytiske preparater inneholdende de rene diastereomerene samt anvendelse av disse for fremstilling av medikamenter NO302122B1 (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4129771		1991-09-07

Publications (3)

Publication Number	Publication Date
NO923452D0 true NO923452D0 (no)	1992-09-04
NO923452L NO923452L (no)	1993-03-08
NO302122B1 NO302122B1 (no)	1998-01-26

Family

ID=6440090

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO923452A NO302122B1 (no)	1991-09-07	1992-09-04	Rene diastereomere av 3-cefem-4-karboksylsyre-1-(isopropoksykarbonyloksy)etylester, farmasöytiske preparater inneholdende de rene diastereomerene samt anvendelse av disse for fremstilling av medikamenter

Country Status (30)

Country	Link
US (3)	US5461043A (no)
EP (1)	EP0531875B1 (no)
JP (1)	JP2667943B2 (no)
KR (1)	KR100239253B1 (no)
CN (1)	CN1040002C (no)
AT (1)	ATE262533T1 (no)
AU (1)	AU647307B2 (no)
BR (1)	BR9203464A (no)
CA (1)	CA2077562C (no)
CZ (1)	CZ282320B6 (no)
DE (1)	DE59209994D1 (no)
DK (1)	DK0531875T3 (no)
EG (1)	EG20237A (no)
ES (1)	ES2215161T3 (no)
FI (1)	FI108725B (no)
HR (1)	HRP920310A2 (no)
HU (1)	HU219588B (no)
IL (1)	IL103064A (no)
MA (1)	MA22646A1 (no)
MX (1)	MX9205081A (no)
NO (1)	NO302122B1 (no)
NZ (1)	NZ244224A (no)
PH (1)	PH30743A (no)
PL (1)	PL171644B1 (no)
PT (1)	PT531875E (no)
RS (1)	RS49877B (no)
RU (1)	RU2075480C1 (no)
SI (1)	SI9200204B (no)
SK (1)	SK276192A3 (no)
ZA (1)	ZA926710B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL99898A (en) *	1990-11-09	1996-10-31	Eisai Co Ltd	7-Acyl-3-substituted carbamoyloxy cephem compounds their preparation and antibacterial compositions containing them
DE59209994D1 (de) *	1991-09-07	2004-04-29	Aventis Pharma Gmbh	Diastereomer des 3-Cephem-4-carbonsäure-1-(-isopropoxycarbonyloxy)ethylesters und Verfahren zu dessen Herstellung
TW212181B (no) *	1992-02-14	1993-09-01	Hoechst Ag
EP0570849B1 (de) *	1992-05-21	1998-03-25	Hoechst Aktiengesellschaft	Verfahren zur Spaltung von Cephalosporin Prodrugestern zu 7-Amino-3-methoxymethylceph-3-em-4-carbonsäure
US5817351A (en) *	1995-04-07	1998-10-06	Abbott Laboratories	Calcium fortified low pH beverage
US5928691A (en) *	1997-05-01	1999-07-27	Nestec S.A.	Calcium complex and a process of making a food fortified with calcium
US6024994A (en) *	1997-11-06	2000-02-15	Nestec S.A.	Calcium complexes for fortification of foods and process of making
AT413383B (de) *	1998-01-09	2006-02-15	Sandoz Ag	Verfahren zur isolierung eines diastereoisomerengemisches von cefpodoxim proxetil
US6036985A (en) *	1998-04-03	2000-03-14	Nestec S.A.	Calcium complex and food fortified therewith
US6039986A (en) *	1998-07-10	2000-03-21	Nestec S.A.	Fortification of foodstuff
AT408226B (de) *	1999-05-05	2001-09-25	Biochemie Gmbh	Kristalliner 7-(2-(2-formylaminothiazol-4-yl)-2
EP1178992A2 (en) *	1999-05-07	2002-02-13	Ranbaxy Laboratories, Limited	Process for the preparation of cefpodoxime acid
IN191496B (no) *	1999-07-30	2003-12-06	Ranbaxy Lab Ltd
US6740344B2 (en) *	2000-12-01	2004-05-25	General Mill, Inc.	Calcium fortified products and methods of preparation
US7045618B2 (en) *	2001-02-27	2006-05-16	Ranbaxy Laboratories Limited	Cefpodixime proxetil
AU2002368494A1 (en) *	2002-12-20	2004-07-14	Lupin Limited	A process for the preparation of cefpodoxime proxetil
EP2520578A1 (en)	2011-05-06	2012-11-07	Lupin Limited	Process for purification of cephalosporins

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4668783A (en) *	1974-12-19	1987-05-26	Takeda Chemical Industries, Ltd.	Thiazolylacetamido cephalosporin compounds
JPS5760345B2 (no) *	1974-12-19	1982-12-18	Takeda Chemical Industries Ltd
DK154939C (da) *	1974-12-19	1989-06-12	Takeda Chemical Industries Ltd	Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
US4203899A (en) *	1974-12-19	1980-05-20	Takeda Chemical Industries, Ltd.	Thiazolylacetamido compounds
US4298606A (en) *	1974-12-19	1981-11-03	Takeda Chemical Industries, Ltd.	Thiazolylacetamido compounds
DE2760123C2 (de) *	1976-01-23	1986-04-30	Roussel-Uclaf, Paris	7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
JPS6011713B2 (ja) *	1976-09-08	1985-03-27	武田薬品工業株式会社	セフアロスポリン誘導体およびその製造法
DE2714880A1 (de) *	1977-04-02	1978-10-26	Hoechst Ag	Cephemderivate und verfahren zu ihrer herstellung
US4409215A (en) *	1979-11-19	1983-10-11	Fujisawa Pharmaceutical Co., Ltd.	7-Acylamino-3-substituted cephalosporanic acid derivatives and processes for the preparation thereof
FR2476087A1 (fr) *	1980-02-18	1981-08-21	Roussel Uclaf	Nouvelles oximes derivees de l'acide 3-alkyloxy ou 3-alkyl-thiomethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
JPS5759894A (en) *	1980-09-30	1982-04-10	Sankyo Co Ltd	Cephalosporin for oral administration
US4486425A (en) *	1980-09-30	1984-12-04	Sankyo Company Limited	7-[2-(2-Aminothiazol-4-yl)-2-(syn)-methoxyiminoacetamido]-3-methoxymethyl-3-cephem-4-carboxylates
JPS5896091A (ja) *	1981-12-01	1983-06-07	Sankyo Co Ltd	３−アルコキシメチルセフアロスポリン類の製造法
US4688783A (en) *	1983-04-20	1987-08-25	Dubois R Clark	Bottom feed sheet feeding apparatus
JPS604189A (ja) *	1983-06-20	1985-01-10	Sankyo Co Ltd	β−ラクタム系化合物の製造法
JPS604190A (ja) *	1983-06-21	1985-01-10	Sankyo Co Ltd	セフアロスポリン誘導体の製法
JPS60260584A (ja) *	1985-05-14	1985-12-23	Sankyo Co Ltd	セフアロスポリン誘導体
DE3804841A1 (de) *	1988-02-17	1989-08-31	Hoechst Ag	Cephalosporinderivate und verfahren zu ihrer herstellung
DE3901405A1 (de) *	1989-01-19	1990-07-26	Hoechst Ag	Cephalosporinderivate und verfahren zu ihrer herstellung
DE3910093A1 (de) *	1989-03-29	1990-10-04	Hoechst Ag	Cephalosporinderivate und verfahren zu ihrer herstellung
US5063224A (en) *	1990-07-09	1991-11-05	Eli Lilly And Company	R-cefuroxime axetil
DE59209994D1 (de) *	1991-09-07	2004-04-29	Aventis Pharma Gmbh	Diastereomer des 3-Cephem-4-carbonsäure-1-(-isopropoxycarbonyloxy)ethylesters und Verfahren zu dessen Herstellung

1992
- 1992-09-02 DE DE59209994T patent/DE59209994D1/de not_active Expired - Lifetime
- 1992-09-02 ES ES92114982T patent/ES2215161T3/es not_active Expired - Lifetime
- 1992-09-02 AT AT92114982T patent/ATE262533T1/de active
- 1992-09-02 PT PT92114982T patent/PT531875E/pt unknown
- 1992-09-02 EP EP92114982A patent/EP0531875B1/de not_active Expired - Lifetime
- 1992-09-02 DK DK92114982T patent/DK0531875T3/da active
- 1992-09-03 US US07/940,367 patent/US5461043A/en not_active Expired - Lifetime
- 1992-09-04 BR BR929203464A patent/BR9203464A/pt not_active Application Discontinuation
- 1992-09-04 HR HR920310A patent/HRP920310A2/hr not_active IP Right Cessation
- 1992-09-04 RU SU925052750A patent/RU2075480C1/ru active
- 1992-09-04 PH PH44890A patent/PH30743A/en unknown
- 1992-09-04 IL IL10306492A patent/IL103064A/en not_active IP Right Cessation
- 1992-09-04 RS YUP-813/92A patent/RS49877B/sr unknown
- 1992-09-04 SK SK2761-92A patent/SK276192A3/sk not_active IP Right Cessation
- 1992-09-04 MX MX9205081A patent/MX9205081A/es unknown
- 1992-09-04 NZ NZ244224A patent/NZ244224A/en not_active IP Right Cessation
- 1992-09-04 NO NO923452A patent/NO302122B1/no not_active IP Right Cessation
- 1992-09-04 FI FI923966A patent/FI108725B/fi not_active IP Right Cessation
- 1992-09-04 PL PL92295834A patent/PL171644B1/pl unknown
- 1992-09-04 CA CA002077562A patent/CA2077562C/en not_active Expired - Lifetime
- 1992-09-04 CZ CS922761A patent/CZ282320B6/cs not_active IP Right Cessation
- 1992-09-04 ZA ZA926710A patent/ZA926710B/xx unknown
- 1992-09-05 KR KR1019920016174A patent/KR100239253B1/ko not_active IP Right Cessation
- 1992-09-05 EG EG52192A patent/EG20237A/xx active
- 1992-09-05 CN CN92110493A patent/CN1040002C/zh not_active Expired - Lifetime
- 1992-09-07 MA MA22936A patent/MA22646A1/fr unknown
- 1992-09-07 SI SI9200204A patent/SI9200204B/sl unknown
- 1992-09-07 HU HU9202861A patent/HU219588B/hu unknown
- 1992-09-07 JP JP4280421A patent/JP2667943B2/ja not_active Expired - Lifetime
- 1992-09-08 AU AU22183/92A patent/AU647307B2/en not_active Expired
1995
- 1995-05-22 US US08/447,229 patent/US5550232A/en not_active Expired - Lifetime
- 1995-05-22 US US08/447,249 patent/US5614623A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CA2077562C (en)	2003-07-15
AU647307B2 (en)	1994-03-17
JP2667943B2 (ja)	1997-10-27
NZ244224A (en)	1995-04-27
EP0531875A2 (de)	1993-03-17
DE59209994D1 (de)	2004-04-29
CN1040002C (zh)	1998-09-30
US5614623A (en)	1997-03-25
RS49877B (sr)	2008-08-07
ZA926710B (en)	1993-04-28
CA2077562A1 (en)	1993-03-08
NO302122B1 (no)	1998-01-26
SK279013B6 (sk)	1998-05-06
HRP920310B1 (no)	2004-12-31
HU219588B (hu)	2001-05-28
HRP920310A2 (en)	1994-08-31
FI923966A (fi)	1993-03-08
BR9203464A (pt)	1993-04-13
PH30743A (en)	1997-10-17
KR100239253B1 (ko)	2000-03-02
MX9205081A (es)	1993-03-01
FI108725B (fi)	2002-03-15
CZ282320B6 (cs)	1997-06-11
IL103064A0 (en)	1993-02-21
EP0531875A3 (en)	1993-03-24
DK0531875T3 (da)	2004-06-21
SK276192A3 (en)	1998-05-06
NO923452L (no)	1993-03-08
HUT64544A (en)	1994-01-28
AU2218392A (en)	1993-03-11
EP0531875B1 (de)	2004-03-24
CZ276192A3 (en)	1993-08-11
HU9202861D0 (en)	1992-11-30
PL295834A1 (en)	1993-03-22
MA22646A1 (fr)	1993-04-01
RU2075480C1 (ru)	1997-03-20
ATE262533T1 (de)	2004-04-15
PT531875E (pt)	2004-08-31
ES2215161T3 (es)	2004-10-01
PL171644B1 (en)	1997-05-30
US5461043A (en)	1995-10-24
CN1070405A (zh)	1993-03-31
US5550232A (en)	1996-08-27
FI923966A0 (fi)	1992-09-04
SI9200204A (en)	1993-03-31
EG20237A (en)	1998-05-31
SI9200204B (en)	2001-12-31
JPH05213969A (ja)	1993-08-24
IL103064A (en)	1996-12-05
KR930006031A (ko)	1993-04-20
YU81392A (sr)	1996-01-09

Publication	Publication Date	Title
NO923452D0 (no)	1992-09-04	Diastereomere av 3-cefem-4-karboksylsyre-1-(isopropoksy-karbonyloksy)etylester og fremgangsmaate for fremstilling derav
US4329453A (en)	1982-05-11	Cephalosporin antibiotic
FI951414A (fi)	1995-03-24	Menetelmä epäpuhtaan klavulaanihapon puhdistamiseksi
KR900014403A (ko)	1990-10-23	신규 화합물
IE50269B1 (en)	1986-03-19	Improvements in or relating to a cephalosporin antibiotic
FI93458B (fi)	1994-12-30	Menetelmä terapeuttisesti käyttökelpoisen 7-/2-(2-aminotiatsol-4-yyli)-2-(Z)-hydroksi-iminoasetamido/-3-(metoksimetyyli)-3-kefeemi-4-karboksyylihappo-/ -(2,2-dimetyylipropionyylioksi)etyyli/esterin diastereomeerin I valmistamiseksi
AU556922B2 (en)	1986-11-27	Pyridobenzodiazepinone derivatives
DE59002880D1 (de)	1993-11-04	Kristalline cephem saeureadditionssalze und verfahren zu ihrer herstellung.
MA19841A1 (fr)	1984-04-01	Procede de preparation de nouveaux derives de cephalosporines utilisables comme antibiotiques .
MX9202460A (es)	1992-11-01	Sales por adicion de acidos cristalinas de esteres 1-(2,2-dimetilpropioniloxi)-etilicos de acidos 3-cefem-4-carboxilicos diastereoisomericamente puros.
JPS57136586A (en)	1982-08-23	Cephalosporin derivative and its preparation
JPS5910592A (ja)	1984-01-20	セファロスポリン系誘導体
SE8105628L (sv)	1983-01-18	Cefalosporinderivat

Legal Events

Date	Code	Title	Description
2012-09-10	MK1K	Patent expired