[go: up one dir, main page]

NO913232D0 - Nye blodplatederiverte vekstfaktor-b-kjedeanaloger og metode for homogen produksjon av disse. - Google Patents

Nye blodplatederiverte vekstfaktor-b-kjedeanaloger og metode for homogen produksjon av disse.

Info

Publication number
NO913232D0
NO913232D0 NO913232A NO913232A NO913232D0 NO 913232 D0 NO913232 D0 NO 913232D0 NO 913232 A NO913232 A NO 913232A NO 913232 A NO913232 A NO 913232A NO 913232 D0 NO913232 D0 NO 913232D0
Authority
NO
Norway
Prior art keywords
analogs
production
pdgf
present
growth factor
Prior art date
Application number
NO913232A
Other languages
English (en)
Norwegian (no)
Other versions
NO913232L (no
Inventor
Arlen Read Thomason
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/454,794 external-priority patent/US5149792A/en
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of NO913232D0 publication Critical patent/NO913232D0/no
Publication of NO913232L publication Critical patent/NO913232L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/49—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
NO91913232A 1989-12-19 1991-08-19 Nye blodplatederiverte vekstfaktor-b-kjedeanaloger og metode for homogen produksjon av disse. NO913232L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/454,794 US5149792A (en) 1989-12-19 1989-12-19 Platelet-derived growth factor B chain analogs
US07/624,451 US5272064A (en) 1989-12-19 1990-12-13 DNA molecules encoding platelet-derived growth factor B chain analogs and method for expression thereof
PCT/US1990/007451 WO1991008761A1 (en) 1989-12-19 1990-12-17 Novel platelet-derived growth factor b chain analogs and method for homogeneous production thereof

Publications (2)

Publication Number Publication Date
NO913232D0 true NO913232D0 (no) 1991-08-19
NO913232L NO913232L (no) 1991-08-19

Family

ID=27037609

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91913232A NO913232L (no) 1989-12-19 1991-08-19 Nye blodplatederiverte vekstfaktor-b-kjedeanaloger og metode for homogen produksjon av disse.

Country Status (17)

Country Link
US (1) US5272064A (de)
EP (1) EP0458959B1 (de)
JP (1) JPH04504064A (de)
AT (1) ATE123949T1 (de)
AU (1) AU646014B2 (de)
CA (1) CA2032675A1 (de)
DE (1) DE69020335T2 (de)
DK (1) DK0458959T3 (de)
ES (1) ES2073735T3 (de)
FI (1) FI913892A0 (de)
GR (1) GR3017317T3 (de)
IE (1) IE904608A1 (de)
IL (1) IL96723A0 (de)
NO (1) NO913232L (de)
NZ (1) NZ236549A (de)
PT (1) PT96272A (de)
WO (1) WO1991008761A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2130748A1 (en) * 1992-02-26 1993-09-02 Michael E. Stern Use of platelet derived growth factor in ophthalmic wound healing
MX9301726A (es) * 1992-03-30 1994-01-31 Schering Corp Factor de crecimiento derivado de plaquetas monomerico y prevencion de estenosis o restenosis.
CA2480121C (en) 2002-03-27 2012-02-28 Immunex Corporation Methods for increasing polypeptide production
US20040248796A1 (en) * 2003-02-04 2004-12-09 Kari Alitalo VEGF-B and PDGF modulation of stem cells
EP2454368A4 (de) 2009-07-17 2013-01-09 Aaron Thomas Tabor Zusammensetzungen und verfahren zur genetischen modifizierung von zellen mit kosmetischer funktion zur verbesserung des kosmetischen erscheinungsbilds
SG187198A1 (en) 2010-08-05 2013-03-28 Amgen Inc Dipeptides to enhance yield and viability from cell cultures
EP4074355A1 (de) 2011-04-20 2022-10-19 Amgen Inc. Autoinjektorvorrichtung
US9133493B2 (en) 2011-04-21 2015-09-15 Amgen Inc. Method for culturing mammalian cells to improve recombinant protein production
KR102108663B1 (ko) 2011-07-01 2020-05-07 암젠 인크 포유동물 세포 배양
EA201490555A1 (ru) 2011-09-02 2014-07-30 Эмджен Инк. Фармацевтический продукт и способ анализа реакции фармацевтического продукта на свет
AR089231A1 (es) 2011-12-15 2014-08-06 Amgen Inc Metodo de floculacion
WO2014109858A1 (en) 2013-01-14 2014-07-17 Amgen Inc. Methods of using cell-cycle inhibitors to modulate one or more properties of a cell culture
MX391507B (es) 2013-03-14 2025-03-21 Amgen Inc Eliminacion de ligandos lixiviados de purificacion de afinidad.
TWI720289B (zh) 2013-03-14 2021-03-01 美商安美基公司 用於增加重組蛋白質之甘露糖含量之方法
US10092703B2 (en) 2013-03-15 2018-10-09 Amgen Inc. Drug cassette, autoinjector, and autoinjector system
BR112015022042B1 (pt) 2013-03-15 2023-01-10 Amgen Inc Injetor para injetar um produto terapêutico
TWI639453B (zh) 2013-03-15 2018-11-01 美商安美基公司 用於注射器之匣盒
US9481901B2 (en) 2013-05-30 2016-11-01 Amgen Inc. Methods for increasing mannose content of recombinant proteins
SMT202500217T1 (it) 2013-10-31 2025-07-22 Amgen Inc Uso di monensin per regolare la glicosilazione di proteine ricombinanti
BR122020004385B1 (pt) 2014-01-13 2022-10-04 Amgen Inc Método para aumentar o teor de glicoforma de alta manose de uma glicoproteína recombinante e método de produção de uma glicoproteína recombinante
US10106829B2 (en) 2014-01-29 2018-10-23 Amgen Inc. Overexpression of N-glycosylation pathway regulators to modulate glycosylation of recombinant proteins
IL282517B (en) 2014-01-29 2022-07-01 Amgen Inc Overexpression of n-glycosylation pathway regulators to modulate glycosylation of recombinant proteins
CA3195249A1 (en) 2014-06-04 2015-12-10 Amgen Inc. Methods for harvesting mammalian cell cultures
MX383470B (es) 2014-11-19 2025-03-14 Amgen Inc Cuantificación de porción de glicano en glicoproteínas recombinantes.
SG10202002458PA (en) 2014-12-01 2020-04-29 Amgen Inc Process for manipulating the level of glycan content of a glycoprotein
EP3710089A1 (de) 2017-11-16 2020-09-23 Amgen Inc. Autoinjektor mit stillstands- und endpunktdetektion
IL307155B1 (en) 2018-05-01 2025-07-01 Amgen Inc Antibodies with a modulated glycan profile
WO2021143699A1 (en) 2020-01-15 2021-07-22 Wuxi Biologics (Shanghai) Co. Ltd. An apparatus and a method for continuously harvesting a biological substance produced by a cultured cell
WO2023079058A1 (en) 2021-11-05 2023-05-11 Yokogawa Insilico Biotechnology Gmbh Cell culture with reduced production of lactate
KR20240128067A (ko) 2021-12-29 2024-08-23 브리스톨-마이어스 스큅 컴퍼니 랜딩 패드 세포주의 생성

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4479896A (en) * 1981-12-11 1984-10-30 Antoniades Harry N Method for extraction localization and direct recovery of platelet derived growth factor
US4769328A (en) * 1984-10-12 1988-09-06 Zymogenetics Inc. Expression of biologically active PDGF analogs in yeast
EP0487116B1 (de) * 1984-10-12 1999-12-29 ZymoGenetics, Inc. Von Blutplättchen abstammende biologisch aktive Analoga eines Wachstumsfaktors in eukaryotischen Zellen
US4766073A (en) * 1985-02-25 1988-08-23 Zymogenetics Inc. Expression of biologically active PDGF analogs in eucaryotic cells
US4801542A (en) * 1984-10-12 1989-01-31 Zymogenetics, Inc. Expression of biologically active PDGF analogs in eucaryotic cells
DE3751632T2 (de) * 1986-08-13 1996-06-13 Zymogenetics Inc Expression von biologisch-aktiven PDGF-Analogen in eukaryotischen Zellen
DE3834079A1 (de) * 1988-10-06 1990-04-12 Biotechnolog Forschung Gmbh Wachstumstimulierendes pdgf-bb und dessen verwendung sowie ein verfahren zu seiner herstellung und der des monomeren
IL96682A0 (en) * 1989-12-15 1991-09-16 Amgen Inc Production of biologically active platelet-derived growth factor from high expression host cell systems

Also Published As

Publication number Publication date
IL96723A0 (en) 1991-09-16
EP0458959B1 (de) 1995-06-21
FI913892A7 (fi) 1991-08-16
JPH04504064A (ja) 1992-07-23
US5272064A (en) 1993-12-21
FI913892A0 (fi) 1991-08-16
WO1991008761A1 (en) 1991-06-27
CA2032675A1 (en) 1991-06-20
DE69020335D1 (de) 1995-07-27
DE69020335T2 (de) 1995-11-02
AU646014B2 (en) 1994-02-03
IE904608A1 (en) 1991-06-19
DK0458959T3 (da) 1995-08-14
GR3017317T3 (en) 1995-12-31
AU7153491A (en) 1991-07-18
PT96272A (pt) 1991-09-30
ATE123949T1 (de) 1995-07-15
NO913232L (no) 1991-08-19
EP0458959A1 (de) 1991-12-04
NZ236549A (en) 1993-03-26
EP0458959A4 (en) 1993-06-16
ES2073735T3 (es) 1995-08-16

Similar Documents

Publication Publication Date Title
NO913232D0 (no) Nye blodplatederiverte vekstfaktor-b-kjedeanaloger og metode for homogen produksjon av disse.
Waterfield et al. Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus
KR880007734A (ko) 폴리펩타이드 유도체
KR880701105A (ko) 신규 응혈촉진 단백질
CA2032153A1 (fr) Application de nouveaux fragments d'adn en tant que sequence codant pour un peptide signal pour la secretion de proteines matures par des levures recombinantes, cassettes d'expression, levures transformees et procede de preparation de proteines correspondant
LU90408I2 (fr) Regranex-becaplermin
EP0722461A4 (de) Expression eines fusionspolypeptides, das ohne leadersequenz aus dem cytoplasma transportiert wird
DE3650645D1 (de) Antigene Proteine und diese enthaltende Impfstoffe zur Verhütung von Kokzidiose
BG101408A (bg) Аналози на кератиноцитния растежен фактор
ATE91722T1 (de) Pferde-gamma-interferon.
DK164940C (da) Polypeptid med human-gamma-interferonaktivitet, genteknologisk fremgangsmaade til fremstilling deraf, hybrid-plasmider indeholdende en dna-sekvens, der koder for peptidet, vaertsorganismer indeholdende hybridplasmiderne, samt laegemidler, som indeholder polypeptidet
DE3852706D1 (de) Verfahren zur Herstellung eines physiologisch aktiven Peptids mit einem Cysteinrest.
ATE103931T1 (de) Polypeptide aus vipergift und deren genexpression.
PT100651A (pt) Muteinas da interleucina 6 (il-6) isentas de cisteina
Proost et al. Chemical synthesis, purification and folding of the human monocyte chemotactic proteins MCP-2 and MCP-3 into biologically active chemokines
JPS6420095A (en) Polypeptide having anti-blood coagulating action
EP0072541A3 (de) Menschliche Leukozyten-Interferone, Verfahren zu deren Mikrobiologischer Herstellung, Zwischenprodukte und diese enthaltende Zusammensetzungen
ATE141645T1 (de) In vitro-behandlung von fusionsproteinen
KR880701073A (ko) 제조합 dna 기법에 의해 생성된 민악티빈
SE8502430D0 (sv) A cdna molecule coding for the expression of an interferon alfa type polypeptide, a bacterial or cellular host transformed with such molecule and a polypeptide showing interferon activity prepared by such host
JPS6437291A (en) Human cytochrome c gene and use thereof
DE60138885D1 (de) Polypeptide mit aktivität der stimulierung von neutrophilen