US6018026A
(en)
|
1988-01-22 |
2000-01-25 |
Zymogenetics, Inc. |
Biologically active dimerized and multimerized polypeptide fusions
|
US5567584A
(en)
*
|
1988-01-22 |
1996-10-22 |
Zymogenetics, Inc. |
Methods of using biologically active dimerized polypeptide fusions to detect PDGF
|
ATE140963T1
(de)
*
|
1988-01-22 |
1996-08-15 |
Zymogenetics Inc |
Verfahren zur herstellung von sekretierten rezeptoranalogen
|
US5750375A
(en)
*
|
1988-01-22 |
1998-05-12 |
Zymogenetics, Inc. |
Methods of producing secreted receptor analogs and biologically active dimerized polypeptide fusions
|
EP0345466A3
(en)
*
|
1988-05-10 |
1991-04-17 |
EASTMAN KODAK COMPANY (a New Jersey corporation) |
Generation of chimeric antibodies in vivo by site-specific recombination
|
EP0397834B1
(en)
|
1988-10-28 |
2000-02-02 |
Genentech, Inc. |
Method for identifying active domains and amino acid residues in polypeptides and hormone variants
|
US6780613B1
(en)
*
|
1988-10-28 |
2004-08-24 |
Genentech, Inc. |
Growth hormone variants
|
DE3909799A1
(de)
*
|
1989-03-24 |
1990-09-27 |
Behringwerke Ag |
Monoklonale antikoerper (mak) gegen tumorassoziierte antigene, ihre herstellung und verwendung
|
ATE236249T1
(de)
|
1989-09-12 |
2003-04-15 |
Hoffmann La Roche |
Tfn-bindende proteine
|
CA2066720A1
(en)
*
|
1989-09-19 |
1991-03-20 |
David M. Knight |
Method for improving human monoclonal antibody production
|
US6713610B1
(en)
|
1990-01-12 |
2004-03-30 |
Raju Kucherlapati |
Human antibodies derived from immunized xenomice
|
US6075181A
(en)
*
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
US6673986B1
(en)
*
|
1990-01-12 |
2004-01-06 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
EP1690935A3
(en)
*
|
1990-01-12 |
2008-07-30 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
US6657103B1
(en)
|
1990-01-12 |
2003-12-02 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
US6150584A
(en)
*
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
US5877397A
(en)
*
|
1990-08-29 |
1999-03-02 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
US5625126A
(en)
*
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
DK0814159T3
(da)
*
|
1990-08-29 |
2005-10-24 |
Genpharm Int |
Transgene, ikke-humane dyr, der er i stand til at danne heterologe antistoffer
|
US5770429A
(en)
*
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US7084260B1
(en)
*
|
1996-10-10 |
2006-08-01 |
Genpharm International, Inc. |
High affinity human antibodies and human antibodies against human antigens
|
US5633425A
(en)
*
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US6300129B1
(en)
|
1990-08-29 |
2001-10-09 |
Genpharm International |
Transgenic non-human animals for producing heterologous antibodies
|
US5874299A
(en)
*
|
1990-08-29 |
1999-02-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US5814318A
(en)
*
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
US7041871B1
(en)
*
|
1995-10-10 |
2006-05-09 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US5545806A
(en)
*
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
US5661016A
(en)
*
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
US7405270B2
(en)
|
1991-10-25 |
2008-07-29 |
Immunex Corporation |
CD40-Ligand lacking native-pattern glycosylation
|
US5962406A
(en)
*
|
1991-10-25 |
1999-10-05 |
Immunex Corporation |
Recombinant soluble CD40 ligand polypeptide and pharmaceutical composition containing the same
|
US5961974A
(en)
|
1991-10-25 |
1999-10-05 |
Immunex Corporation |
Monoclonal antibodies to CD40 ligand, pharmaceutical composition comprising the same and hybridomas producing the same
|
US5981724A
(en)
|
1991-10-25 |
1999-11-09 |
Immunex Corporation |
DNA encoding CD40 ligand, a cytokine that binds CD40
|
EP0867511A1
(en)
*
|
1992-03-10 |
1998-09-30 |
La Jolla Cancer Research Foundation |
Recombinant calf intestinal alkaline phosphatase
|
US5736137A
(en)
*
|
1992-11-13 |
1998-04-07 |
Idec Pharmaceuticals Corporation |
Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
|
KR100463476B1
(ko)
*
|
1993-12-23 |
2005-07-01 |
머크 앤드 캄파니 인코포레이티드 |
쥐과의동물세포들을위한상동성재조합항체발현시스템
|
HU221513B
(en)
|
1993-12-23 |
2002-10-28 |
Merck & Co Inc |
Homologous recombination antibody expression system
|
EP0742830B1
(en)
|
1994-02-01 |
2001-07-18 |
THE UNITED STATES OF AMERICA, as represented by the Secretary of the Department of Health and Human Services |
Fusion proteins that include antibody and nonantibody portions
|
US5541110A
(en)
|
1994-05-17 |
1996-07-30 |
Bristol-Myers Squibb |
Cloning and expression of a gene encoding bryodin 1 from Bryonia dioica
|
EP0823941A4
(en)
*
|
1995-04-28 |
2001-09-19 |
Abgenix Inc |
HUMAN ANTIBODIES DERIVED FROM IMMUNIZED XENO MOUSES
|
CZ299025B6
(cs)
|
1996-02-09 |
2008-04-02 |
Amgen Inc. |
Farmaceutická kompozice a její použití
|
ES2384942T3
(es)
*
|
1996-12-03 |
2012-07-16 |
Amgen Fremont Inc. |
Anticuerpos humanos que se unen específicamente al TNF alfa
|
CA2273852C
(en)
|
1996-12-06 |
2009-09-29 |
Amgen Inc. |
Combination therapy using an il-1 inhibitor for treating il-1 mediated diseases
|
DK0966533T3
(da)
|
1997-02-07 |
2010-01-04 |
Us Gov Health & Human Serv |
Aktivitetsafhængig neurotrof faktor III (ADNF III).
|
ATE501170T1
(de)
|
1997-04-07 |
2011-03-15 |
Genentech Inc |
Verfahren zur herstellung humanisierter antikörper durch randomisierte mutagenese
|
DK0973804T3
(da)
|
1997-04-07 |
2007-05-07 |
Genentech Inc |
Anti-VEGF-antistoffer
|
US7087420B1
(en)
|
1997-07-17 |
2006-08-08 |
Cambia |
Microbial β-glucuronidase genes, gene products and uses thereof
|
US6391547B1
(en)
*
|
1997-09-09 |
2002-05-21 |
Center For The Application Of Molecular Biology To International Agriculture |
Microbial β-glucuronidase genes, gene products and uses thereof
|
NZ520579A
(en)
*
|
1997-10-24 |
2004-08-27 |
Invitrogen Corp |
Recombinational cloning using nucleic acids having recombination sites and methods for synthesizing double stranded nucleic acids
|
US6528624B1
(en)
*
|
1998-04-02 |
2003-03-04 |
Genentech, Inc. |
Polypeptide variants
|
US7183387B1
(en)
|
1999-01-15 |
2007-02-27 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
US6737056B1
(en)
*
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
EP1141024B1
(en)
*
|
1999-01-15 |
2018-08-08 |
Genentech, Inc. |
POLYPEPTIDE COMPRISING A VARIANT HUMAN IgG1 Fc REGION
|
US6864235B1
(en)
*
|
1999-04-01 |
2005-03-08 |
Eva A. Turley |
Compositions and methods for treating cellular response to injury and other proliferating cell disorders regulated by hyaladherin and hyaluronans
|
US6911429B2
(en)
*
|
1999-04-01 |
2005-06-28 |
Transition Therapeutics Inc. |
Compositions and methods for treating cellular response to injury and other proliferating cell disorders regulated by hyaladherin and hyaluronans
|
EP1292619B1
(en)
|
2000-06-06 |
2008-02-06 |
Bristol-Myers Squibb Company |
B7-related nucleic acids and polypeptides and their uses for immunomodulation
|
MXPA03001915A
(es)
*
|
2000-08-03 |
2004-09-10 |
Therapeutic Human Polyclonals |
Produccion de anticuerpos humanizados en animales transgenicos.
|
DE60131456T2
(de)
*
|
2000-11-30 |
2008-07-10 |
Medarex, Inc., Milpitas |
Transchromosomale transgen-nagetiere zur herstellung von humanen antikörpern
|
US7476536B2
(en)
*
|
2001-05-11 |
2009-01-13 |
Kirin Pharma Kabushiki Kaisha |
Artificial human chromosome containing human antibody a light chain gene
|
NZ532526A
(en)
*
|
2001-10-25 |
2007-01-26 |
Genentech Inc |
Compositions comprising a glycoprotein having a Fc region
|
EP1451323A2
(en)
*
|
2001-11-09 |
2004-09-01 |
Transition Therapeutics Inc. |
Pharmaceutical compositions of marine sponge microciona prolifera
|
US7332585B2
(en)
|
2002-04-05 |
2008-02-19 |
The Regents Of The California University |
Bispecific single chain Fv antibody molecules and methods of use thereof
|
EP1572121B1
(en)
|
2002-08-01 |
2012-01-11 |
The Regents of The University of California |
Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins
|
ES2373947T3
(es)
*
|
2002-12-16 |
2012-02-10 |
Genmab A/S |
Anticuerpos monoclonales humanos contra interleucina 8 (il-8).
|
AR045614A1
(es)
*
|
2003-09-10 |
2005-11-02 |
Hoffmann La Roche |
Anticuerpos contra el recepctor de la interleuquina- 1 y los usos de los mismos
|
US7932242B2
(en)
|
2004-03-16 |
2011-04-26 |
Temple University - Of The Commonwealth System Of Higher Education |
Substituted phenoxy-and phenylthio-derivatives for treating proliferative disorders
|
WO2005095458A1
(en)
*
|
2004-04-02 |
2005-10-13 |
The Talwar Research Foundation |
CHIMERIC MONOCLONAL ANTIBODY FOR BINDING WITH HIGH AFFINITY SELECTIVELY TO hCG
|
US7794713B2
(en)
|
2004-04-07 |
2010-09-14 |
Lpath, Inc. |
Compositions and methods for the treatment and prevention of hyperproliferative diseases
|
JP4633788B2
(ja)
|
2004-04-13 |
2011-02-16 |
エフ.ホフマン−ラ ロシュ アーゲー |
抗p−セレクチン抗体
|
TWI309240B
(en)
|
2004-09-17 |
2009-05-01 |
Hoffmann La Roche |
Anti-ox40l antibodies
|
BRPI0516011A
(pt)
|
2004-09-24 |
2008-08-19 |
Amgen Inc |
moléculas fc modificadas
|
CN101107007B
(zh)
|
2005-01-27 |
2011-08-17 |
奥克兰儿童医院及研究中心 |
对脑膜炎奈瑟球菌所致疾病具有广谱保护作用的gna1870囊泡疫苗
|
JP2008528060A
(ja)
|
2005-01-27 |
2008-07-31 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
ボツリヌス神経毒素を中和する治療的モノクローナル抗体
|
TW200720289A
(en)
*
|
2005-04-01 |
2007-06-01 |
Hoffmann La Roche |
Antibodies against CCR5 and uses thereof
|
US8008453B2
(en)
|
2005-08-12 |
2011-08-30 |
Amgen Inc. |
Modified Fc molecules
|
WO2007019865A2
(en)
*
|
2005-08-18 |
2007-02-22 |
Genmab A/S |
Therapy with cd4 binding peptides and radiation
|
US20090074720A1
(en)
*
|
2005-10-28 |
2009-03-19 |
Sabbadini Roger A |
Methods for decreasing immune response and treating immune conditions
|
US20080213274A1
(en)
*
|
2005-10-28 |
2008-09-04 |
Sabbadini Roger A |
Compositions and methods for the treatment and prevention of fibrotic, inflammatory, and neovascularization conditions of the eye
|
WO2007117410A2
(en)
*
|
2006-03-31 |
2007-10-18 |
Medarex, Inc. |
Transgenic animals expressing chimeric antibodies for use in preparing human antibodies
|
US20080014203A1
(en)
*
|
2006-04-11 |
2008-01-17 |
Silke Hansen |
Antibodies against insulin-like growth factor I receptor and uses thereof
|
US7846724B2
(en)
|
2006-04-11 |
2010-12-07 |
Hoffmann-La Roche Inc. |
Method for selecting CHO cell for production of glycosylated antibodies
|
US7862812B2
(en)
*
|
2006-05-31 |
2011-01-04 |
Lpath, Inc. |
Methods for decreasing immune response and treating immune conditions
|
JP2010500984A
(ja)
|
2006-08-17 |
2010-01-14 |
エフ.ホフマン−ラ ロシュ アーゲー |
Ccr5に対する抗体と抗膜融合ペプチドとの抱合体
|
TW200817438A
(en)
*
|
2006-08-17 |
2008-04-16 |
Hoffmann La Roche |
A conjugate of an antibody against CCR5 and an antifusogenic peptide
|
CN102719444B
(zh)
|
2006-09-01 |
2016-12-14 |
人类多细胞株治疗学公司 |
人或人源化免疫球蛋白在非人转基因动物中增强的表达
|
ATE550355T1
(de)
|
2006-09-29 |
2012-04-15 |
Hoffmann La Roche |
Antikörper gegen ccr5 und ihre verwendung
|
US7767206B2
(en)
|
2006-10-02 |
2010-08-03 |
Amgen Inc. |
Neutralizing determinants of IL-17 Receptor A and antibodies that bind thereto
|
DK2087002T3
(da)
*
|
2006-10-27 |
2014-10-27 |
Lpath Inc |
Sammensætninger og fremgangsmåder til binding af sphingosin-1-phosphat
|
US8444970B2
(en)
*
|
2006-10-27 |
2013-05-21 |
Lpath, Inc. |
Compositions and methods for treating ocular diseases and conditions
|
US20080226635A1
(en)
*
|
2006-12-22 |
2008-09-18 |
Hans Koll |
Antibodies against insulin-like growth factor I receptor and uses thereof
|
US9163091B2
(en)
*
|
2007-05-30 |
2015-10-20 |
Lpath, Inc. |
Compositions and methods for binding lysophosphatidic acid
|
ES2585702T3
(es)
*
|
2007-05-30 |
2016-10-07 |
Lpath, Inc |
Composiciones y métodos para la unión al ácido lisofosfatídico
|
HUE037060T2
(hu)
*
|
2007-06-29 |
2018-08-28 |
Hoffmann La Roche |
Javított immunglobulin-termeléshez vezetõ nehézlánc-mutáns
|
CL2008002092A1
(es)
|
2007-07-20 |
2009-05-29 |
Hoffmann La Roche |
Conjugado que contiene dos o mas peptidos antifusogenicos y un anticuerpo anti-cd-4; metodo de produccion; composicion farmaceutica que lo comprende; polipeptidos antifusogenicos y uso del conjugado para tratar infecciones viricas.
|
EP2197918B1
(en)
|
2007-09-05 |
2013-12-18 |
F. Hoffmann-La Roche AG |
Combination therapy with type i and type ii anti-cd20 antibodies
|
EP2192922A4
(en)
|
2007-09-17 |
2010-09-29 |
Univ California |
INTERNATIONALIZING HUMAN MONOCLONAL ANTIBODIES TO PROMOTE IN SITU ON PROSTATAZELLES
|
AU2008309934B2
(en)
|
2007-10-12 |
2014-03-06 |
F. Hoffmann-La Roche Ag |
Protein expression from multiple nucleic acids
|
US20090098118A1
(en)
|
2007-10-15 |
2009-04-16 |
Thomas Friess |
Combination therapy of a type ii anti-cd20 antibody with an anti-bcl-2 active agent
|
US8361465B2
(en)
*
|
2007-10-26 |
2013-01-29 |
Lpath, Inc. |
Use of anti-sphingosine-1-phosphate antibodies in combination with chemotherapeutic agents
|
CN101896820A
(zh)
*
|
2007-12-15 |
2010-11-24 |
霍夫曼-拉罗奇有限公司 |
区分测定
|
US8227577B2
(en)
*
|
2007-12-21 |
2012-07-24 |
Hoffman-La Roche Inc. |
Bivalent, bispecific antibodies
|
US9266967B2
(en)
|
2007-12-21 |
2016-02-23 |
Hoffmann-La Roche, Inc. |
Bivalent, bispecific antibodies
|
US20090162359A1
(en)
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
WO2009083246A1
(en)
|
2007-12-31 |
2009-07-09 |
Bayer Schering Pharma Aktiengesellschaft |
Antibodies to tnf alpha
|
DK2238170T3
(en)
|
2008-01-31 |
2017-02-27 |
Inserm - Inst Nat De La Santé Et De La Rech Médicale |
ANTIBODIES AGAINST HUMAN CD39 AND ITS USE FOR INHIBITING ACTIVITY OF T-REGULATORY CELLS
|
DK2279004T3
(en)
|
2008-05-16 |
2015-02-02 |
Hoffmann La Roche |
USE OF biomarkers for assessment of treatment of gastrointestinal inflammatory disorders WITH beta7 integrin antagonists
|
US8790642B2
(en)
|
2008-08-29 |
2014-07-29 |
Genentech, Inc. |
Cross-reactive and bispecific anti-IL-17A/F antibodies
|
WO2010039900A2
(en)
|
2008-09-30 |
2010-04-08 |
Aliva Biopharmaceuticals, Inc. |
Non-human mammals for the production of chimeric antibodies
|
WO2010040766A1
(en)
|
2008-10-07 |
2010-04-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Neutralizing antibodies and fragments thereof directed against platelet factor-4 variant 1 (pf4v1)
|
US8268314B2
(en)
*
|
2008-10-08 |
2012-09-18 |
Hoffmann-La Roche Inc. |
Bispecific anti-VEGF/anti-ANG-2 antibodies
|
US8871202B2
(en)
|
2008-10-24 |
2014-10-28 |
Lpath, Inc. |
Prevention and treatment of pain using antibodies to sphingosine-1-phosphate
|
WO2010069858A1
(en)
*
|
2008-12-19 |
2010-06-24 |
F. Hoffmann-La Roche Ag |
Pharmaceutical composition
|
EP2398913B1
(en)
|
2009-02-20 |
2016-03-30 |
F. Hoffmann-La Roche AG |
Method for obtaining immunoglobulin encoding nucleic acid
|
WO2010106051A1
(en)
|
2009-03-17 |
2010-09-23 |
Universite De La Mediterranee |
Btla antibodies and uses thereof
|
CN102361632A
(zh)
|
2009-03-30 |
2012-02-22 |
弗·哈夫曼-拉罗切有限公司 |
避免玻璃雾化的方法
|
AR075982A1
(es)
|
2009-03-31 |
2011-05-11 |
Roche Glycart Ag |
Terapia de combinacion de un anticuerpo afucosilado y una o mas de las citoquinas seleccionadas de gm- csf humano, m -csf humano y/o il-3 humano y composicion
|
EP2236139A1
(en)
|
2009-03-31 |
2010-10-06 |
F. Hoffmann-La Roche AG |
Combination therapy of erlotinib with an anti-IGF-1R antibody, which does not inhibit binding of insulin to the insulin receptor
|
US8093006B2
(en)
|
2009-04-02 |
2012-01-10 |
Hoffmann-La Roche Inc. |
Antibodies against human tweak and uses thereof
|
WO2010112194A1
(en)
|
2009-04-02 |
2010-10-07 |
F. Hoffmann-La Roche Ag |
Antigen-binding polypeptides and multispecific antibodies comprising them
|
RU2598248C2
(ru)
|
2009-04-02 |
2016-09-20 |
Роше Гликарт Аг |
Полиспецифичные антитела, включающие антитела полной длины и одноцепочечные фрагменты fab
|
WO2010115552A1
(en)
|
2009-04-07 |
2010-10-14 |
Roche Glycart Ag |
Bispecific anti-erbb-3/anti-c-met antibodies
|
SI2417156T1
(sl)
|
2009-04-07 |
2015-06-30 |
Roche Glycart Ag |
Trivalentna, bispecifiäśna protitelesa
|
KR20110124368A
(ko)
|
2009-04-07 |
2011-11-16 |
로슈 글리카트 아게 |
이중특이적 항―erbb―2/항―c―met 항체
|
PE20120540A1
(es)
|
2009-05-27 |
2012-05-09 |
Hoffmann La Roche |
Anticuerpos triespecificos o tetraespecificos
|
US9676845B2
(en)
|
2009-06-16 |
2017-06-13 |
Hoffmann-La Roche, Inc. |
Bispecific antigen binding proteins
|
JP5758888B2
(ja)
|
2009-07-06 |
2015-08-05 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
二重特異性ジゴキシゲニン結合抗体
|
ES2538819T3
(es)
|
2009-07-30 |
2015-06-24 |
F. Hoffmann-La Roche Ag |
Procesamiento enzimático de anticuerpos
|
AU2010280847B2
(en)
|
2009-08-04 |
2012-12-13 |
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Beta cell marker antibody
|
US20110039300A1
(en)
|
2009-08-10 |
2011-02-17 |
Robert Bayer |
Antibodies with enhanced adcc functions
|
US20110053223A1
(en)
|
2009-08-14 |
2011-03-03 |
Robert Bayer |
Cell culture methods to make antibodies with enhanced adcc function
|
JP2013501741A
(ja)
|
2009-08-14 |
2013-01-17 |
ロシュ グリクアート アーゲー |
アフコシル化cd20抗体とフルダラビン及び/又はミトキサントロンの併用療法
|
TWI409079B
(zh)
|
2009-08-14 |
2013-09-21 |
Roche Glycart Ag |
非典型岩藻醣化cd20抗體與苯達莫斯汀(bendamustine)之組合療法
|
TW201113037A
(en)
|
2009-08-28 |
2011-04-16 |
Hoffmann La Roche |
Antibodies against CDCP1 for the treatment of cancer
|
TWI412375B
(zh)
|
2009-08-28 |
2013-10-21 |
Roche Glycart Ag |
人類化抗cdcp1抗體
|
EP2289542A1
(en)
|
2009-08-31 |
2011-03-02 |
PAION Deutschland GmbH |
Treatment of neurological or neurodegenerative disorders
|
WO2011026640A1
(en)
|
2009-09-07 |
2011-03-10 |
F. Hoffmann-La Roche Ag |
Es-ms of glycopeptides for analysis of glycosylation
|
AR078161A1
(es)
|
2009-09-11 |
2011-10-19 |
Hoffmann La Roche |
Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento.
|
NZ598962A
(en)
|
2009-09-16 |
2014-12-24 |
Genentech Inc |
Coiled coil and/or tether containing protein complexes and uses thereof
|
AU2010303142B2
(en)
|
2009-09-29 |
2013-05-09 |
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Bispecific death receptor agonistic antibodies
|
TW201117824A
(en)
|
2009-10-12 |
2011-06-01 |
Amgen Inc |
Use of IL-17 receptor a antigen binding proteins
|
SG2014014823A
(en)
|
2009-10-19 |
2014-07-30 |
Hoffmann La Roche |
Non-cross-reactive anti igg antibodies
|
ES2981683T3
(es)
|
2009-10-26 |
2024-10-10 |
Hoffmann La Roche |
Procedimiento para la producción de una inmunoglobulina glucosilada
|
WO2011064179A1
(en)
|
2009-11-26 |
2011-06-03 |
F. Hoffmann-La Roche Ag |
Marker protein for type 2 diabetes
|
SI2949670T1
(sl)
|
2009-12-10 |
2019-05-31 |
F. Hoffmann-La Roche Ag |
Protitelesa, ki se preferenčno vežejo na zunajcelično domeno 4 človeškega CSF1R, in njihova uporaba
|
AU2010335282B2
(en)
|
2009-12-22 |
2015-05-21 |
Roche Glycart Ag |
Anti-HER3 antibodies and uses thereof
|
EP2516460B1
(en)
|
2009-12-22 |
2015-03-04 |
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Sequence dependent aggregation
|
ES2753216T3
(es)
|
2010-01-15 |
2020-04-07 |
Amgen K A Inc |
Formulación de anticuerpos anti-IL17RA y regímenes terapéuticos para el tratamiento de la psoriasis
|
US20120294866A1
(en)
|
2010-01-19 |
2012-11-22 |
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Pharmaceutical formulation for proteins
|
WO2011101328A2
(en)
|
2010-02-18 |
2011-08-25 |
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Treatment with a humanized igg class anti egfr antibody and an antibody against insulin like growth factor 1 receptor
|
BR112012022046A2
(pt)
|
2010-03-05 |
2017-02-14 |
F Hoffamann-La Roche Ag |
''anticorpo,composição farmacêutica,ácido nucleico ,vetores de expressão,célula hospedeira e método para a produção de um anticorpo recombinante''.
|
JP2013521765A
(ja)
|
2010-03-05 |
2013-06-13 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
ヒトcsf−1rに対する抗体及びその使用
|
WO2011119549A1
(en)
|
2010-03-22 |
2011-09-29 |
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|
AR080793A1
(es)
|
2010-03-26 |
2012-05-09 |
Roche Glycart Ag |
Anticuerpos biespecificos
|
TWI426920B
(zh)
*
|
2010-03-26 |
2014-02-21 |
Hoffmann La Roche |
雙專一性、雙價抗-vegf/抗-ang-2抗體
|
DK2553100T3
(en)
|
2010-03-31 |
2017-10-23 |
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REPLACING NON-HUMAN ANIMALS TO CREATE CHIMERARY ANTIBODIES
|
JP6042801B2
(ja)
|
2010-04-27 |
2016-12-14 |
ロシュ グリクアート アーゲー |
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|
EP2596025B1
(en)
|
2010-07-23 |
2018-06-20 |
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|
RU2603284C2
(ru)
|
2010-08-17 |
2016-11-27 |
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|
TW201208703A
(en)
|
2010-08-17 |
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Combination therapy of an afucosylated CD20 antibody with an anti-VEGF antibody
|
JP5758004B2
(ja)
|
2010-08-24 |
2015-08-05 |
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|
WO2012027440A1
(en)
|
2010-08-24 |
2012-03-01 |
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Hiv core protein specific antibodies and uses thereof
|
SG188605A1
(en)
|
2010-10-05 |
2013-04-30 |
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Antibodies against human tweak and uses thereof
|
DK2633289T3
(en)
|
2010-10-25 |
2016-06-06 |
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USE OF SIGNAL enhancing compounds in electrochemiluminesce DETECTION
|
WO2012080769A1
(en)
|
2010-12-15 |
2012-06-21 |
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|
CA2819436A1
(en)
|
2010-12-16 |
2012-06-21 |
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Combination therapy of an afucosylated cd20 antibody with a mdm2 inhibitor
|
EP2655412B1
(en)
|
2010-12-21 |
2018-01-17 |
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Isoform enriched antibody preparation and method for obtaining it
|
EP2654789B1
(en)
|
2010-12-22 |
2018-05-30 |
Orega Biotech |
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|
SG191153A1
(en)
|
2010-12-23 |
2013-07-31 |
Hoffmann La Roche |
Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery
|
WO2012101125A1
(en)
|
2011-01-24 |
2012-08-02 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
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|
MX341921B
(es)
|
2011-02-28 |
2016-09-07 |
Hoffmann La Roche |
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|
KR101572338B1
(ko)
|
2011-02-28 |
2015-11-26 |
에프. 호프만-라 로슈 아게 |
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|
SI2686334T2
(sl)
|
2011-03-16 |
2020-10-30 |
F. Hoffmann-La Roche Ag |
Ionska izmenjevalna kromatografija z izboljšano selektivnostjo za ločevanje polipeptidnih monomerov, agregatov in fragmentov s spremembo mobilne faze
|
BR112013024574B1
(pt)
|
2011-03-29 |
2022-08-09 |
Roche Glycart Ag |
Anticorpo e uso do anticorpo
|
BR112013025045B1
(pt)
|
2011-03-31 |
2020-10-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
anticorpos direcionados contra icos e usos dos mesmos
|
EP3412309A1
(en)
|
2011-03-31 |
2018-12-12 |
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Methods of administering beta7 integrin antagonists
|
AR086250A1
(es)
|
2011-05-05 |
2013-11-27 |
Hoffmann La Roche |
Polipeptido de fusion presentador de una secuencia de aminoacidos y utilizacion del mismo
|
ES2643694T3
(es)
|
2011-05-19 |
2017-11-23 |
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Anticuerpos anti-HER3 humanos y sus usos
|
BR112013032233A2
(pt)
|
2011-06-15 |
2016-11-22 |
Hoffmann La Roche |
ligação de anticorpo ao polipeptídeo abca1
|
KR20140104945A
(ko)
|
2011-06-22 |
2014-08-29 |
인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) |
항-axl 항체 및 그의 용도
|
EP2723376B1
(en)
|
2011-06-22 |
2018-12-05 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Anti-axl antibodies and uses thereof
|
EP2543678A1
(en)
|
2011-07-08 |
2013-01-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies for the treatment and prevention of thrombosis
|
EP2543679A1
(en)
|
2011-07-08 |
2013-01-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies for the treatment and prevention of thrombosis
|
EP2543677A1
(en)
|
2011-07-08 |
2013-01-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies for the treatment and prevention of thrombosis
|
WO2013016220A1
(en)
|
2011-07-22 |
2013-01-31 |
Amgen Inc. |
Il-17 receptor a is required for il-17c biology
|
BR112014004166A2
(pt)
|
2011-08-23 |
2018-05-29 |
Roche Glycart Ag |
anticorpo biespecífico compreendendo pelo menos dois fragmentos fab, célula hospedeira procariótica ou eucariótica, metodo de produção de um anticorpo, imunoconjugado e invenção
|
KR101870555B1
(ko)
|
2011-08-23 |
2018-06-22 |
로슈 글리카트 아게 |
T 세포 활성화 항원 및 종양 항원에 대해 특이적인 이중특이적 항체 및 이의 사용 방법
|
SG10201912955PA
(en)
|
2011-09-19 |
2020-02-27 |
Axon Neuroscience Se |
Protein-based therapy and diagnosis of tau-mediated pathology in alzheimer's disease
|
US20150024434A1
(en)
|
2011-09-21 |
2015-01-22 |
Hoffmann-La Roche Inc. |
METHOD FOR OBTAINING FAB FRAGMENTS FROM SINGLE ANTIBODY PRODUCING CELLS BY MULTIPLEXED CPR IN COMBINATION WITH TaqMan PROBES
|
EP2758435A1
(en)
|
2011-09-23 |
2014-07-30 |
Roche Glycart AG |
Bispecific anti-egfr/anti igf-1r antibodies
|
SG2014012470A
(en)
|
2011-10-05 |
2014-06-27 |
Hoffmann La Roche |
Process for antibody g1 glycoform production
|
US20130302274A1
(en)
|
2011-11-25 |
2013-11-14 |
Roche Glycart Ag |
Combination therapy
|
US10023643B2
(en)
|
2011-12-15 |
2018-07-17 |
Hoffmann-La Roche Inc. |
Antibodies against human CSF-1R and uses thereof
|
FR2984750B1
(fr)
|
2011-12-23 |
2014-01-10 |
Lfb Biotechnologies |
Nouvelles compositions pharmaceutiques comprenant un anticorps liant le recepteur humain de l'hormone anti-mullerienne de type ii
|
EP2812357B1
(en)
|
2012-02-10 |
2020-11-04 |
F.Hoffmann-La Roche Ag |
Single-chain antibodies and other heteromultimers
|
CN104136460A
(zh)
|
2012-02-29 |
2014-11-05 |
霍夫曼-拉罗奇有限公司 |
减少1->3读框移位的方法
|
KR20140135716A
(ko)
|
2012-02-29 |
2014-11-26 |
에프. 호프만-라 로슈 아게 |
1→2 해독 프레임 이동의 감소 방법
|
AR090263A1
(es)
|
2012-03-08 |
2014-10-29 |
Hoffmann La Roche |
Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma
|
SG11201404481RA
(en)
|
2012-03-08 |
2014-09-26 |
Hoffmann La Roche |
Abeta antibody formulation
|
AR090244A1
(es)
|
2012-03-08 |
2014-10-29 |
Hoffmann La Roche |
Formulacion de anticuerpo anti-selectina p
|
MX2014011818A
(es)
|
2012-04-05 |
2014-12-10 |
Hoffmann La Roche |
Anticuerpos biespecificos contra inductor debil de la apoptosis relacionado con el tnf (tweak) humana e il17 humana y usos de los mismos.
|
EP2666786A1
(en)
|
2012-05-21 |
2013-11-27 |
PAION Deutschland GmbH |
Immunotherapy for intracranial hemorrhage
|
EP2855531A1
(en)
|
2012-05-24 |
2015-04-08 |
F. Hoffmann-La Roche AG |
Multispecific antibodies
|
EP3505534A1
(en)
|
2012-06-08 |
2019-07-03 |
Sutro Biopharma, Inc. |
Antibodies comprising sitespecific nonnatural amino acid residues, methods of their preparation and methods of their use
|
EP2864355B1
(en)
|
2012-06-25 |
2016-10-12 |
Orega Biotech |
Il-17 antagonist antibodies
|
CA2871880A1
(en)
|
2012-06-27 |
2014-01-03 |
F. Hoffmann-La Roche Ag |
Method for selection and production of tailor-made highly selective and multi-specific targeting entities containing at least two different binding entities and uses thereof
|
KR20150030744A
(ko)
|
2012-06-27 |
2015-03-20 |
에프. 호프만-라 로슈 아게 |
표적에 특이적으로 결합하는 하나 이상의 결합 단위를 포함하는 항체 Fc-영역 접합체의 제조 방법 및 그의 용도
|
EP2684896A1
(en)
|
2012-07-09 |
2014-01-15 |
International-Drug-Development-Biotech |
Anti-DR5 family antibodies, bispecific or multivalent anti-DR5 family antibodies and methods of use thereof
|
SMT202100621T1
(it)
|
2012-07-13 |
2022-01-10 |
Roche Glycart Ag |
Anticorpi bispecifici anti-vegf/anti-ang-2 e loro impiego nel trattamento delle malattie vascolari oculari
|
ES2684552T3
(es)
|
2012-09-03 |
2018-10-03 |
Inserm - Institut National De La Santé Et De La Recherche Médicale |
Anticuerpos dirigidos contra ICOS para tratar la enfermedad de injerto contra hospedador
|
CN104768581A
(zh)
|
2012-09-07 |
2015-07-08 |
吉宁特有限公司 |
II型抗CD20抗体与选择性Bcl-2抑制剂的组合治疗
|
AU2013326921C1
(en)
|
2012-10-05 |
2018-01-18 |
Genentech, Inc. |
Methods for diagnosing and treating inflammatory bowel disease
|
US10087250B2
(en)
|
2012-10-08 |
2018-10-02 |
Roche Glycart Ag |
Fc-free antibodies comprising two fab-fragments and methods of use
|
EP2727943A1
(en)
|
2012-11-05 |
2014-05-07 |
MAB Discovery GmbH |
Trispecific antibodies against human EGFR, HER2 and HER3
|
EP2727942A1
(en)
|
2012-11-05 |
2014-05-07 |
MAB Discovery GmbH |
Bispecific antibodies against human EGFR, HER2, and HER3
|
EP2727941A1
(en)
|
2012-11-05 |
2014-05-07 |
MAB Discovery GmbH |
Method for the production of multispecific antibodies
|
WO2014067642A1
(en)
|
2012-11-05 |
2014-05-08 |
Mab Discovery Gmbh |
Method for the production of multispecific antibodies
|
EP2733153A1
(en)
|
2012-11-15 |
2014-05-21 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for the preparation of immunoconjugates and uses thereof
|
UA120247C2
(uk)
|
2012-11-20 |
2019-11-11 |
Санофі |
Антитіло до ceacam5 і його застосування
|
JP6408478B2
(ja)
|
2012-11-26 |
2018-10-17 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
トリオキサカルシン、トリオキサカルシン−抗体複合体、およびその用途
|
WO2014093417A1
(en)
|
2012-12-12 |
2014-06-19 |
University Of Virginia Patent Foundation |
Compositions and methods for regulating erythropoiesis
|
JP6461808B2
(ja)
|
2012-12-17 |
2019-01-30 |
ラボラトワール フランセ ドゥ フラクションマン エ デ バイオテクノロジーズLaboratoire Francais Du Fractionnement Et Des Biotechnologies |
炎症および細菌感染症処置におけるモノクローナル抗体の使用
|
ES2871816T3
(es)
|
2012-12-27 |
2021-11-02 |
Sanofi Sa |
Anticuerpos anti-LAMP1 y conjugados anticuerpo-fármaco, y usos de los mismos
|
US9180185B2
(en)
|
2013-01-11 |
2015-11-10 |
Hoffman-La Roche Inc. |
Combination therapy of anti-HER3 antibodies
|
EP2762497A1
(en)
|
2013-02-05 |
2014-08-06 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
EP2953972B1
(en)
|
2013-02-05 |
2020-07-08 |
EngMab Sàrl |
Method for the selection of antibodies against bcma
|
EP2762496A1
(en)
|
2013-02-05 |
2014-08-06 |
EngMab AG |
Method for the selection of antibodies against BCMA
|
EP3495814A3
(en)
|
2013-03-27 |
2019-07-17 |
F. Hoffmann-La Roche AG |
Use of biomarkers for assessing treatment of gastrointestinal inflammatory disorders with beta7 integrin antagonists
|
WO2014161570A1
(en)
|
2013-04-03 |
2014-10-09 |
Roche Glycart Ag |
Antibodies against human il17 and uses thereof
|
UA118028C2
(uk)
|
2013-04-03 |
2018-11-12 |
Рош Глікарт Аг |
Біспецифічне антитіло, специфічне щодо fap і dr5, антитіло, специфічне щодо dr5, і спосіб їх застосування
|
EP2789630A1
(en)
|
2013-04-09 |
2014-10-15 |
EngMab AG |
Bispecific antibodies against CD3e and ROR1
|
AR095882A1
(es)
|
2013-04-22 |
2015-11-18 |
Hoffmann La Roche |
Terapia de combinación de anticuerpos contra csf-1r humano con un agonista de tlr9
|
WO2014183885A1
(en)
|
2013-05-17 |
2014-11-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antagonist of the btla/hvem interaction for use in therapy
|
ES2658039T3
(es)
|
2013-07-10 |
2018-03-08 |
Sutro Biopharma, Inc. |
Anticuerpos que comprenden múltiples residuos de aminoácidos no naturales sitio-específicos, métodos para su preparación y métodos de uso
|
WO2015014979A1
(en)
|
2013-08-01 |
2015-02-05 |
F. Hoffmann-La Roche Ag |
Tnfa-il-17 bispecific antibodies
|
EP2832854A1
(en)
|
2013-08-02 |
2015-02-04 |
F. Hoffmann-La Roche AG |
Method for improving the recombinant expression of a polypeptide by C-terminal fusion to human neprilysin
|
AR097584A1
(es)
|
2013-09-12 |
2016-03-23 |
Hoffmann La Roche |
Terapia de combinación de anticuerpos contra el csf-1r humano y anticuerpos contra el pd-l1 humano
|
RU2016115866A
(ru)
|
2013-10-11 |
2017-11-16 |
Ф. Хоффманн-Ля Рош Аг |
Мультиспецифические антитела с обменянными доменами и одинаковыми вариабельными доменами легкой цепи
|
RU2704228C2
(ru)
|
2013-11-07 |
2019-10-24 |
Инсерм (Институт Насьональ Де Ла Сант Эт Де Ла Решерш Медикаль) |
Неконкурентные в отношении нейрегулина аллостерические антитела против человеческого her3 и их применения
|
WO2015082446A1
(en)
|
2013-12-02 |
2015-06-11 |
F. Hoffmann-La Roche Ag |
Treatment of cancer using an anti-cdcp1 antibody and a taxane
|
AU2015235986B2
(en)
|
2014-03-27 |
2020-12-03 |
Genentech, Inc. |
Methods for diagnosing and treating inflammatory bowel disease
|
KR102530900B1
(ko)
|
2014-03-31 |
2023-05-12 |
암젠 케이-에이, 인크. |
손발톱 및 두피 건선의 치료 방법
|
UA117289C2
(uk)
|
2014-04-02 |
2018-07-10 |
Ф. Хоффманн-Ля Рош Аг |
Мультиспецифічне антитіло
|
ES2924393T3
(es)
|
2014-04-16 |
2022-10-06 |
Inst Nat Sante Rech Med |
Anticuerpos para la prevención o el tratamiento de episodios hemorrágicos
|
FR3020063A1
(fr)
|
2014-04-16 |
2015-10-23 |
Gamamabs Pharma |
Anticorps humain anti-her4
|
EP3172233B1
(en)
|
2014-07-22 |
2019-09-11 |
Sutro Biopharma, Inc. |
Anti-cd74 antibodies, compositions comprising anti-cd74 antibodies and methods of using anti-cd74 antibodies
|
JP6692343B2
(ja)
|
2014-08-01 |
2020-05-13 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
薬物としての使用のための抗cd45rc抗体
|
EP2982692A1
(en)
|
2014-08-04 |
2016-02-10 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
US11952421B2
(en)
|
2014-10-09 |
2024-04-09 |
Bristol-Myers Squibb Company |
Bispecific antibodies against CD3EPSILON and ROR1
|
WO2016059220A1
(en)
|
2014-10-16 |
2016-04-21 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Tcr-activating agents for use in the treatment of t-all
|
RU2730668C2
(ru)
|
2014-11-19 |
2020-08-24 |
Аксон Ньюросайенс Се |
Гуманизированные тау-антитела при болезни альцгеймера
|
ES2984937T3
(es)
|
2014-11-20 |
2024-10-31 |
Hoffmann La Roche |
Politerapia de moléculas de unión a antígeno biespecíficas activadoras de linfocitos T y antagonistas de la unión al eje de PD-1
|
EP3023437A1
(en)
|
2014-11-20 |
2016-05-25 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
EP3029068A1
(en)
|
2014-12-03 |
2016-06-08 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA for use in the treatment of diseases
|
CN107001482B
(zh)
|
2014-12-03 |
2021-06-15 |
豪夫迈·罗氏有限公司 |
多特异性抗体
|
UA126269C2
(uk)
|
2015-01-23 |
2022-09-14 |
Санофі |
АНТИТІЛОПОДІБНИЙ ЗВ’ЯЗУВАЛЬНИЙ БІЛОК, ЯКИЙ СПЕЦИФІЧНО ЗВ’ЯЗУЄТЬСЯ З ПОЗАКЛІТИННИМ ДОМЕНОМ CD3<font face="Symbol">e</font> ЛЮДИНИ І З CD123<font face="Symbol">e</font>
|
CN107257693A
(zh)
|
2015-02-26 |
2017-10-17 |
豪夫迈·罗氏有限公司 |
治疗Crohn病的整联蛋白β7拮抗剂和方法
|
EP3280455A1
(en)
|
2015-04-07 |
2018-02-14 |
INSERM - Institut National de la Santé et de la Recherche Médicale |
Non-invasive imaging of tumor pd-l1 expression
|
EP3091033A1
(en)
|
2015-05-06 |
2016-11-09 |
Gamamabs Pharma |
Anti-human-her3 antibodies and uses thereof
|
WO2016207124A1
(en)
|
2015-06-25 |
2016-12-29 |
F. Hoffmann-La Roche Ag |
Cell based assay for determining antibody or ligand binding and function
|
AU2016282869B2
(en)
|
2015-06-26 |
2022-08-18 |
Sanofi Biotechnology SAS |
Monoclonal anti-IL-1RAcP antibodies
|
PT3319995T
(pt)
|
2015-07-07 |
2019-06-14 |
H Hoffnabb La Roche Ag |
Terapêutica combinada de um conjugado anticorpo anti-her2-fármaco com um inibidor de bcl-2
|
WO2017005847A1
(en)
|
2015-07-07 |
2017-01-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies having specificity to myosin 18a and uses thereof
|
EP3328886B1
(en)
|
2015-07-29 |
2020-09-16 |
Allergan, Inc. |
Heavy chain only antibodies to ang-2
|
US10683369B2
(en)
|
2015-08-03 |
2020-06-16 |
Engmab Sàrl |
Monoclonal antibodies against BCMA
|
EP3331569A1
(en)
|
2015-08-07 |
2018-06-13 |
Gamamabs Pharma |
Antibodies, antibody drug conjugates and methods of use
|
WO2017030909A1
(en)
|
2015-08-14 |
2017-02-23 |
Allergan, Inc. |
Heavy chain only antibodies to pdgf
|
EP3998076A1
(en)
|
2015-09-17 |
2022-05-18 |
Histide AG |
Pharmaceutical association of growth factor receptor agonist and adhesion protein inhibitor for converting a neoplastic cell into a non-neoplastic cell and uses thereof
|
EP3906932A3
(en)
|
2015-09-17 |
2021-12-01 |
Histide AG |
Pharmaceutical association of growth factor receptor agonist and adhesion protein inhibitor for converting a neoplastic cell into a non-neoplastic cell and uses thereof
|
WO2017060397A1
(en)
|
2015-10-09 |
2017-04-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the survival time of subjects suffering from melanoma metastases
|
WO2017070460A1
(en)
|
2015-10-22 |
2017-04-27 |
Massachusetts Institute Of Technology |
Vegf-a-binding proteins and her2-binding proteins with enhanced stability against aggregation
|
US20190330336A1
(en)
|
2015-11-19 |
2019-10-31 |
Sutro Biopharma, Inc. |
Anti-lag3 antibodies, compositions comprising anti-lag3 antibodies and methods of making and using anti-lag3 antibodies
|
PT3383920T
(pt)
|
2015-11-30 |
2024-04-15 |
Univ California |
Entrega de carga útil específica para tumores e ativação imune utilizando um anticorpo humano que tem como alvo um antigénio altamente específico da superfície das células tumorais
|
SG11201804957VA
(en)
|
2015-12-16 |
2018-07-30 |
Gritstone Oncology Inc |
Neoantigen identification, manufacture, and use
|
SG11201806419RA
(en)
|
2016-01-27 |
2018-08-30 |
Sutro Biopharma Inc |
Anti-cd74 antibody conjugates, compositions comprising anti-cd74 antibody conjugates and methods of using anti-cd74 antibody conjugates
|
BR112018067525A2
(pt)
|
2016-02-26 |
2019-02-05 |
Centre Nat Rech Scient |
anticorpos tendo especificidade para o btla e seus usos
|
EP3423490A1
(en)
|
2016-03-01 |
2019-01-09 |
H. Hoffnabb-La Roche Ag |
Obinutuzumab and rituximab variants having reduced adcp
|
CN108698047B
(zh)
|
2016-03-11 |
2022-04-01 |
豪夫迈·罗氏有限公司 |
电化学发光检测中的支链胺
|
GB201604458D0
(en)
|
2016-03-16 |
2016-04-27 |
Immatics Biotechnologies Gmbh |
Peptides and combination of peptides for use in immunotherapy against cancers
|
EP3241845A1
(en)
|
2016-05-06 |
2017-11-08 |
MAB Discovery GmbH |
Humanized anti-il-1r3 antibodies
|
EP3472197A1
(en)
|
2016-06-15 |
2019-04-24 |
Sutro Biopharma, Inc. |
Antibodies with engineered ch2 domains, compositions thereof and methods of using the same
|
TWI790206B
(zh)
|
2016-07-18 |
2023-01-21 |
法商賽諾菲公司 |
特異性結合至cd3和cd123的雙特異性抗體樣結合蛋白
|
EP3491022A1
(en)
|
2016-07-29 |
2019-06-05 |
Institut National de la Sante et de la Recherche Medicale (INSERM) |
Antibodies targeting tumor associated macrophages and uses thereof
|
EP3504239B1
(en)
|
2016-08-25 |
2024-05-29 |
F. Hoffmann-La Roche AG |
Intermittent dosing of an anti-csf-1r antibody in combination with macrophage activating agent
|
WO2018049261A1
(en)
|
2016-09-09 |
2018-03-15 |
Icellhealth Consulting Llc |
Oncolytic virus expressing immune checkpoint modulators
|
WO2018071597A1
(en)
|
2016-10-12 |
2018-04-19 |
Sutro Biopharma, Inc. |
Anti-folate receptor antibodies, compositions comprising anti-folate receptor antibodies and methods of making and using anti-folate receptor antibodies
|
TWI778985B
(zh)
|
2016-10-20 |
2022-10-01 |
法商賽諾菲公司 |
抗chikv抗體及其用途
|
EP3535295A1
(en)
|
2016-11-02 |
2019-09-11 |
EngMab Sàrl |
Bispecific antibody against bcma and cd3 and an immunological drug for combined use in treating multiple myeloma
|
US10316037B1
(en)
|
2016-11-04 |
2019-06-11 |
Yale University |
Compounds and methods for treating cancer
|
US12049511B2
(en)
|
2016-11-10 |
2024-07-30 |
Fortis Therapeutics, Inc. |
Engineered CD46-specific effector cells and uses thereof in the treatment of cancer
|
JOP20190100A1
(ar)
|
2016-11-19 |
2019-05-01 |
Potenza Therapeutics Inc |
بروتينات ربط مولد ضد مضاد لـ gitr وطرق استخدامها
|
WO2018091720A1
(en)
|
2016-11-21 |
2018-05-24 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the prophylactic treatment of metastases
|
CA3045323A1
(en)
|
2016-12-02 |
2018-06-07 |
Juno Therapeutics, Inc. |
Engineered b cells and related compositions and methods
|
EP3555620A1
(en)
|
2016-12-13 |
2019-10-23 |
H. Hoffnabb-La Roche Ag |
Method to determine the presence of a target antigen in a tumor sample
|
WO2018114772A1
(en)
|
2016-12-21 |
2018-06-28 |
F. Hoffmann-La Roche Ag |
Assay for determining antibody or ligand binding and function
|
JP6931058B2
(ja)
|
2016-12-21 |
2021-09-01 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
抗体のインビトロ糖鎖工学における酵素の再使用
|
MX2019006266A
(es)
|
2016-12-21 |
2019-08-21 |
Hoffmann La Roche |
Glucomanipulacion in vitro de anticuerpos.
|
CN110088292A
(zh)
|
2016-12-21 |
2019-08-02 |
豪夫迈·罗氏有限公司 |
用于体外糖工程化抗体的方法
|
CN110072553B
(zh)
|
2016-12-22 |
2023-09-15 |
豪夫迈·罗氏有限公司 |
在抗pd-l1/pd1治疗失败之后抗csf-1r抗体与抗pd-l1抗体组合对肿瘤的治疗
|
JOP20190134A1
(ar)
|
2016-12-23 |
2019-06-02 |
Potenza Therapeutics Inc |
بروتينات رابطة لمولد ضد مضادة لنيوروبيلين وطرق استخدامها
|
WO2018122053A1
(en)
|
2016-12-29 |
2018-07-05 |
F. Hoffmann-La Roche Ag |
Anti-angiopoietin-2 antibody formulation
|
WO2018156785A1
(en)
|
2017-02-22 |
2018-08-30 |
Sutro Biopharma, Inc. |
Pd-1/tim-3 bi-specific antibodies, compositions thereof, and methods of making and using the same
|
CN110392697A
(zh)
|
2017-03-02 |
2019-10-29 |
国家医疗保健研究所 |
对nectin-4具有特异性的抗体及其用途
|
JP7308150B2
(ja)
|
2017-03-16 |
2023-07-13 |
イナート・ファルマ・ソシエテ・アノニム |
癌を処置するための組成物及び方法
|
JOP20190203A1
(ar)
|
2017-03-30 |
2019-09-03 |
Potenza Therapeutics Inc |
بروتينات رابطة لمولد ضد مضادة لـ tigit وطرق استخدامها
|
EP3401332A1
(en)
|
2017-05-08 |
2018-11-14 |
MAB Discovery GmbH |
Anti-il-1r3 antibodies for use in inflammatory conditions
|
WO2018217940A2
(en)
|
2017-05-24 |
2018-11-29 |
Sutro Biopharma, Inc. |
Pd-1/lag3 bi-specific antibodies, compositions thereof, and methods of making and using the same
|
US11464845B2
(en)
|
2017-07-21 |
2022-10-11 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neisseria meningitidis immunogenic compositions
|
US11174322B2
(en)
|
2017-07-24 |
2021-11-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies and peptides to treat HCMV related diseases
|
WO2019023316A1
(en)
|
2017-07-26 |
2019-01-31 |
Sutro Biopharma, Inc. |
METHODS OF USING ANTI-CD74 ANTIBODIES AND ANTIBODY CONJUGATES IN THE TREATMENT OF A T CELL LYMPHOMA
|
KR102670957B1
(ko)
|
2017-07-26 |
2024-05-31 |
포티 세븐, 인코포레이티드 |
항-sirp-알파 항체 및 관련 방법
|
EP3658584A1
(en)
|
2017-07-26 |
2020-06-03 |
H. Hoffnabb-La Roche Ag |
Combination therapy with a bet inhibitor, a bcl-2 inhibitor and an anti-cd20 antibody
|
KR20200051802A
(ko)
|
2017-09-18 |
2020-05-13 |
서트로 바이오파마, 인크. |
항-엽산 수용체 알파 항체 접합체 및 이의 용도
|
CA3074933A1
(en)
|
2017-09-21 |
2019-03-28 |
Imcheck Therapeutics Sas |
Antibodies having specificity for btn2 and uses thereof
|
AU2018348165A1
(en)
|
2017-10-10 |
2020-05-21 |
Gritstone Bio, Inc. |
Neoantigen identification using hotspots
|
EP3710482A4
(en)
|
2017-11-14 |
2021-08-18 |
University Of Virginia Patent Foundation |
COMPOSITIONS AND METHODS OF MANUFACTURING AND USING BISPECIFIC ANTIBODIES
|
IL274799B1
(en)
|
2017-11-22 |
2025-01-01 |
Gritstone Bio Inc |
Reducing epitope binding presentation for neoantigens
|
GB201719646D0
(en)
|
2017-11-27 |
2018-01-10 |
Bivictrix Therapeutics Ltd |
Therapy
|
CN111491951B
(zh)
|
2017-12-22 |
2024-05-24 |
豪夫迈·罗氏有限公司 |
通过疏水相互作用色谱法耗尽轻链错配的抗体变体
|
MX2020007077A
(es)
|
2018-01-04 |
2020-10-28 |
Iconic Therapeutics Inc |
Anticuerpos anti-factor tisular, conjugados anticuerpo-farmaco y metodos relacionados.
|
CA3084370A1
(en)
|
2018-01-12 |
2019-07-18 |
Bristol-Myers Squibb Company |
Combination therapy with anti-il-8 antibodies and anti-pd-1 antibodies for treating cancer
|
IL276383B2
(en)
|
2018-02-06 |
2024-01-01 |
Hoffmann La Roche |
Treatment of ophthalmological diseases
|
US11993658B2
(en)
|
2018-03-26 |
2024-05-28 |
Sutro Biopharma, Inc. |
Anti-BCMA antibodies and treatment methods
|
MX2020009991A
(es)
|
2018-03-28 |
2020-10-14 |
Axon Neuroscience Se |
Metodos basados en anticuerpos para detectar y tratar la enfermedad de alzheimer.
|
WO2019195561A2
(en)
|
2018-04-06 |
2019-10-10 |
BioLegend, Inc. |
Anti-tetraspanin 33 agents and compositions and methods for making and using the same
|
CN113166218B
(zh)
|
2018-04-11 |
2024-08-13 |
信立泰生物医药公司 |
人神经调节蛋白-1(nrg-1)重组融合蛋白组合物和其使用方法
|
GB201807367D0
(en)
|
2018-05-04 |
2018-06-20 |
Univ Newcastle |
Biomarker
|
WO2019231326A1
(en)
|
2018-05-31 |
2019-12-05 |
ACADEMISCH ZIEKENHUIS LEIDEN (h.o.d.n.LUMC) |
Teipp neoantigens and uses thereof
|
US11377503B2
(en)
|
2018-06-18 |
2022-07-05 |
Innate Pharma |
Antibodies that bind human CD39 and inhibit ATPase activity of a soluble extracellular domain human CD39 polypeptide
|
CN113614112A
(zh)
|
2018-09-10 |
2021-11-05 |
莱顿教学医院 |
MuSK抑制
|
US20240043562A1
(en)
|
2018-09-10 |
2024-02-08 |
ACADEMISCH ZIEKENHUIS LEIDEN (h.o.d.n. LUMC) |
Musk activation
|
US20220047716A1
(en)
|
2018-09-17 |
2022-02-17 |
Sutro Biopharma, Inc. |
Combination therapies with anti-folate receptor antibody conjugates
|
EP3856343A1
(en)
|
2018-09-25 |
2021-08-04 |
Biolegend, Inc. |
Anti-tlr9 agents and compositions and methods for making and using the same
|
AU2019346598A1
(en)
|
2018-09-27 |
2021-04-29 |
Tizona Therapeutics |
Anti- HLA-G antibodies, compositions comprising anti- HLA-G antibodies and methods of using anti- HLA-G antibodies
|
GB201816554D0
(en)
|
2018-10-10 |
2018-11-28 |
Centauri Therapeutics Ltd |
Novel compounds and therapeutic uses thereof
|
GB201816553D0
(en)
|
2018-10-10 |
2018-11-28 |
Centauri Therapeutics Ltd |
Novel compounds and therapeutic uses thereof
|
KR102590359B1
(ko)
|
2018-10-29 |
2023-10-16 |
에프. 호프만-라 로슈 아게 |
항체 제형
|
WO2020089437A1
(en)
|
2018-10-31 |
2020-05-07 |
Engmab Sàrl |
Combination therapy
|
EP3877413A1
(en)
|
2018-11-06 |
2021-09-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment of acute myeloid leukemia by eradicating leukemic stem cells
|
US11827710B2
(en)
|
2019-02-11 |
2023-11-28 |
Zumutor Biologics Inc. |
Antibodies that bind to c-type lectin domain family 2 member d (CLEC2D)
|
MX2021011334A
(es)
|
2019-03-20 |
2021-12-10 |
Imcheck Therapeutics Sas |
Anticuerpos que tienen especificidad para btn2 y usos de los mismos.
|
EP3947446A1
(en)
|
2019-03-25 |
2022-02-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Treatment of taupathy disorders by targeting new tau species
|
JP2022531001A
(ja)
|
2019-05-03 |
2022-07-05 |
セルジーン コーポレーション |
抗bcma抗体コンジュゲート、そのコンジュゲートを含む組成物ならびにそのコンジュゲートの製造および使用方法
|
US20220362394A1
(en)
|
2019-05-03 |
2022-11-17 |
Sutro Biopharma, Inc. |
Anti-bcma antibody conjugates
|
US20220242871A1
(en)
|
2019-06-10 |
2022-08-04 |
Sutro Biopharma, Inc. |
5H-PYRROLO[3,2-d]PYRIMIDINE-2,4-DIAMINO COMPOUNDS AND ANTIBODY CONJUGATES THEREOF
|
EP3983410A1
(en)
|
2019-06-17 |
2022-04-20 |
Sutro Biopharma, Inc. |
1-(4-(aminomethyl)benzyl)-2-butyl-2h-pyrazolo[3,4-c]quinolin-4-amine derivatives and related compounds as toll-like receptor (tlr) 7/8 agonists, as well as antibody drug conjugates thereof for use in cancer therapy and diagnosis
|
DE102019121007A1
(de)
|
2019-08-02 |
2021-02-04 |
Immatics Biotechnologies Gmbh |
Antigenbindende Proteine, die spezifisch an MAGE-A binden
|
EP4007775A1
(en)
|
2019-08-02 |
2022-06-08 |
Orega Biotech |
Novel il-17b antibodies
|
US20210032370A1
(en)
|
2019-08-02 |
2021-02-04 |
Immatics Biotechnologies Gmbh |
Recruiting agent further binding an mhc molecule
|
EP3825330A1
(en)
|
2019-11-19 |
2021-05-26 |
International-Drug-Development-Biotech |
Anti-cd117 antibodies and methods of use thereof
|
WO2021146383A1
(en)
|
2020-01-17 |
2021-07-22 |
BioLegend, Inc. |
Anti-tlr7 agents and compositions and methods for making and using the same
|
AU2021225962A1
(en)
|
2020-02-28 |
2022-10-20 |
Genzyme Corporation |
Modified binding polypeptides for optimized drug conjugation
|
WO2021175954A1
(en)
|
2020-03-04 |
2021-09-10 |
Imcheck Therapeutics Sas |
Antibodies having specificity for btnl8 and uses thereof
|
CN115843268A
(zh)
|
2020-04-17 |
2023-03-24 |
纽约大学 |
治疗性MuSK抗体
|
EP4139340A1
(en)
|
2020-04-22 |
2023-03-01 |
Merck Sharp & Dohme LLC |
Human interleukin-2 conjugates biased for the interleukin-2 receptor beta gammac dimer and conjugated to a nonpeptidic, water-soluble polymer
|
EP4142722A1
(en)
|
2020-04-30 |
2023-03-08 |
Bristol-Myers Squibb Company |
Methods of treating cytokine-related adverse events
|
CN115551553A
(zh)
|
2020-05-12 |
2022-12-30 |
Inserm(法国国家健康医学研究院) |
治疗皮肤t细胞淋巴瘤和tfh起源淋巴瘤的新方法
|
EP3915641A1
(en)
|
2020-05-27 |
2021-12-01 |
International-Drug-Development-Biotech |
Anti-cd5 antibodies and methods of use thereof
|
US20240148889A1
(en)
|
2020-06-11 |
2024-05-09 |
President And Fellows Of Harvard College |
Stabilized trioxacarcin antibody drug conjugates and uses thereof
|
BR112022026359A2
(pt)
|
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Prevenção de dano axonal usando anticorpo que se liga ao beta amiloide 1-42
|
MX2023001625A
(es)
|
2020-08-07 |
2023-05-16 |
Fortis Therapeutics Inc |
Inmunoconjugados que se dirigen a cd46 y metodos de uso de los mismos.
|
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(en)
|
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|
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(en)
|
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Treatment of idiopathic pulmonary fibrosis
|
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(en)
|
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Imp College Innovations Ltd |
Proteome analysis in pulmonary hypertension
|
WO2022093641A1
(en)
|
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Anti-nkg2a agents and compositions and methods for making and using the same
|
WO2022093640A1
(en)
|
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Anti-nkg2c agents and compositions and methods for making and using the same
|
GB202017673D0
(en)
|
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2020-12-23 |
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Treatment of pulmonary arterial hypertensive
|
WO2022153212A1
(en)
|
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Axon Neuroscience Se |
Antibodies neutralizing sars-cov-2
|
WO2022184805A1
(en)
|
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Immatics Biotechnologies Gmbh |
Antigen binding proteins specifically binding sars-cov-2 antigenic peptides in complex with a major histocompatibility complex protein
|
TW202308702A
(zh)
|
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2023-03-01 |
美商西建公司 |
使用抗BCMA抗體藥物結合物(ADC)組合γ分泌酶抑制劑(GSI)之組合療法
|
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(en)
|
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Sutro Biopharma, Inc. |
Anti-folate receptor conjugate combination therapy with bevacizumab
|
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(zh)
|
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2023-06-01 |
德商英麥提克生物技術股份有限公司 |
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|
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(en)
|
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Immunitas Therapeutics, Inc. |
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|
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(zh)
|
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新型抗体-细胞因子融合蛋白及其制备方法和用途
|
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(zh)
|
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美商建南德克公司 |
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|
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(en)
|
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President And Fellows Of Harvard College |
C-16 modified trioxacarcins, antibody drug conjugates, and uses thereof
|
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(en)
|
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Sutro Biopharma, Inc. |
Anti-folate receptor conjugate cancer therapy
|
WO2023170239A1
(en)
|
2022-03-09 |
2023-09-14 |
Merck Patent Gmbh |
Methods and tools for conjugation to antibodies
|
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(en)
|
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2024-10-01 |
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Binding molecules against frα
|
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(en)
|
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A SCORING METHOD FOR AN ANTI-FRα ANTIBODY-DRUG CONJUGATE THERAPY
|
WO2023178086A1
(en)
|
2022-03-15 |
2023-09-21 |
Salubris Biotherapeutics, Inc. |
Methods of treating fibrosis and arrhythmia with a neuregulin-1 fusion protein
|
WO2024006563A1
(en)
|
2022-07-01 |
2024-01-04 |
Sutro Biopharma, Inc. |
Il-12 mutants with reduced toxicity, compositions thereof and methods of using the same
|
WO2024020051A1
(en)
|
2022-07-19 |
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BioLegend, Inc. |
Anti-cd157 antibodies, antigen-binding fragments thereof and compositions and methods for making and using the same
|
WO2024040114A2
(en)
|
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|
WO2024044780A1
(en)
|
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Interleukin-18 variants and uses thereof
|
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(en)
|
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Humanized anti-il-1r3 antibody and methods of use
|
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(en)
|
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Interferon alpha polypeptides and conjugates
|
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(en)
|
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Academisch Ziekenhuis Leiden |
Novel C1q antibodies and uses thereof
|
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(en)
|
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ACADEMISCH ZIEKENHUIS LEIDEN (h.o.d.n. LUMC) |
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|
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(en)
|
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Combination therapies for treatment of cancer with therapeutic binding molecules
|
WO2025006737A1
(en)
|
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The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Genetically detoxified mutant of neisseria and outer membrane vesicle (omv) vaccine
|
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(en)
|
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Novel t cell receptors targeting melanoma-associated antigen (mage) b2 and immune therapy using the same
|
WO2025021968A1
(en)
|
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|