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NO883963L - Modifiserte plasminogenaktivatorer. - Google Patents

Modifiserte plasminogenaktivatorer.

Info

Publication number
NO883963L
NO883963L NO88883963A NO883963A NO883963L NO 883963 L NO883963 L NO 883963L NO 88883963 A NO88883963 A NO 88883963A NO 883963 A NO883963 A NO 883963A NO 883963 L NO883963 L NO 883963L
Authority
NO
Norway
Prior art keywords
dna
upa
region
fragment
amino acid
Prior art date
Application number
NO88883963A
Other languages
English (en)
Norwegian (no)
Other versions
NO883963D0 (no
Inventor
Giovanni Cassani
Marialuisa Nolli
Francesco Blasi
Federico Maria Robbiati
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of NO883963D0 publication Critical patent/NO883963D0/no
Publication of NO883963L publication Critical patent/NO883963L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6456Plasminogen activators
    • C12N9/6462Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21073Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
NO88883963A 1987-09-07 1988-09-06 Modifiserte plasminogenaktivatorer. NO883963L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878721023A GB8721023D0 (en) 1987-09-07 1987-09-07 Modified plasminogen activators

Publications (2)

Publication Number Publication Date
NO883963D0 NO883963D0 (no) 1988-09-06
NO883963L true NO883963L (no) 1989-03-08

Family

ID=10623401

Family Applications (1)

Application Number Title Priority Date Filing Date
NO88883963A NO883963L (no) 1987-09-07 1988-09-06 Modifiserte plasminogenaktivatorer.

Country Status (14)

Country Link
EP (1) EP0308716A3 (xx)
JP (1) JPH01117785A (xx)
KR (1) KR890005267A (xx)
CN (1) CN1033070A (xx)
AU (1) AU2196688A (xx)
DK (1) DK491988A (xx)
FI (1) FI883943A (xx)
GB (1) GB8721023D0 (xx)
HU (1) HUT47975A (xx)
IL (1) IL87638A (xx)
NO (1) NO883963L (xx)
NZ (1) NZ226050A (xx)
PT (1) PT88436B (xx)
ZA (1) ZA886401B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5098840A (en) * 1986-07-03 1992-03-24 The Green Cross Corporation Human prourokinase mutants
AU5515790A (en) * 1989-05-18 1990-11-22 Green Cross Corporation, The Human prourokinase variants, methods of producing same, dna sequences, plasmids and hosts therefor
CA2025181A1 (en) * 1989-10-12 1991-04-13 William G. Weisburg Nucleic acid probes and methods for detecting fungi
JPH0595786A (ja) * 1991-10-07 1993-04-20 Green Cross Corp:The 変異ヒトプロウロキナーゼ
US6120765A (en) * 1993-04-02 2000-09-19 Shiseido Co. Ltd. Urokinase plasminogen activator fragments
CA2605127C (en) 2005-04-19 2011-08-09 Archer-Daniels-Midland Company Soluble non-caloric fiber composition and process of preparing the same
TWI369402B (en) 2006-07-05 2012-08-01 Catalyst Biosciences Inc Protease screening methods and proteases identified thereby
JP2010512324A (ja) 2006-12-08 2010-04-22 アッテヌオン エル エル シー ウロキナーゼ型プラスミノーゲン活性化因子受容体エピトープ、それに由来するモノクローナル抗体及びそれらの使用方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8801374A1 (es) * 1985-04-04 1988-01-01 Beecham Group Plc Un procedimiento para preparar un activante de plasminogeno.
JPH0761266B2 (ja) * 1986-07-03 1995-07-05 株式会社ミドリ十字 変異ヒトプロウロキナ−ゼ
EP0266032A1 (en) * 1986-08-29 1988-05-04 Beecham Group Plc Modified fibrinolytic enzyme
IE880255L (en) * 1987-01-30 1988-07-30 American Home Prod Des-epidermal growth factor activators.

Also Published As

Publication number Publication date
FI883943A0 (fi) 1988-08-26
DK491988A (da) 1989-03-08
NZ226050A (en) 1991-06-25
IL87638A (en) 1993-04-04
JPH01117785A (ja) 1989-05-10
EP0308716A2 (en) 1989-03-29
NO883963D0 (no) 1988-09-06
KR890005267A (ko) 1989-05-13
PT88436A (pt) 1989-07-31
AU2196688A (en) 1989-06-08
CN1033070A (zh) 1989-05-24
FI883943A (fi) 1989-03-08
IL87638A0 (en) 1989-01-31
PT88436B (pt) 1992-11-30
GB8721023D0 (en) 1987-10-14
ZA886401B (en) 1989-07-26
DK491988D0 (da) 1988-09-05
EP0308716A3 (en) 1989-06-14
HUT47975A (en) 1989-04-28

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