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NO852501L - Nye epoksysteroider. - Google Patents

Nye epoksysteroider.

Info

Publication number
NO852501L
NO852501L NO852501A NO852501A NO852501L NO 852501 L NO852501 L NO 852501L NO 852501 A NO852501 A NO 852501A NO 852501 A NO852501 A NO 852501A NO 852501 L NO852501 L NO 852501L
Authority
NO
Norway
Prior art keywords
cysteroids
new epoxy
epoxy
new
epoxy cysteroids
Prior art date
Application number
NO852501A
Other languages
English (en)
Other versions
NO165496B (no
NO165496C (no
Inventor
Michel Biolaz
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO852501L publication Critical patent/NO852501L/no
Publication of NO165496B publication Critical patent/NO165496B/no
Publication of NO165496C publication Critical patent/NO165496C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0011Androstane derivatives substituted in position 17 by a keto group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J13/00Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005Ketals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J53/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002Carbocyclic rings fused
    • C07J53/0043 membered carbocyclic rings
    • C07J53/0083 membered carbocyclic rings in position 15/16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes
    • C07J71/0015Oxiranes at position 9(11)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO852501A 1984-06-21 1985-06-20 Analogifremgangsmaate for fremstilling av nye epoksysteroider. NO165496C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH300984 1984-06-21
CH464684 1984-09-28

Publications (3)

Publication Number Publication Date
NO852501L true NO852501L (no) 1985-12-23
NO165496B NO165496B (no) 1990-11-12
NO165496C NO165496C (no) 1991-02-20

Family

ID=25691934

Family Applications (1)

Application Number Title Priority Date Filing Date
NO852501A NO165496C (no) 1984-06-21 1985-06-20 Analogifremgangsmaate for fremstilling av nye epoksysteroider.

Country Status (16)

Country Link
US (1) US4670551A (no)
EP (1) EP0165902B1 (no)
AR (2) AR242036A1 (no)
AU (1) AU582754B2 (no)
CA (1) CA1239388A (no)
DE (1) DE3569540D1 (no)
DK (1) DK173854B1 (no)
ES (2) ES8704967A1 (no)
FI (1) FI83225C (no)
GR (1) GR851499B (no)
HU (1) HU192232B (no)
IE (1) IE58050B1 (no)
IL (1) IL75569A (no)
NO (1) NO165496C (no)
NZ (1) NZ212492A (no)
PT (1) PT80663B (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA009176B1 (ru) 1995-12-11 2007-12-28 Дж.Д.Серл Энд Ко. Способ получения 7-альфа-карбоксил-9,11-эпоксистероидов и промежуточных продуктов, используемых для их получения, и общий способ эпоксидирования по олефиновым двойным связям
IL130182A0 (en) * 1996-12-11 2000-06-01 Searle & Co Processes for preparation of 9,11-epoxy steroids and intermediates useful therein
US6887991B1 (en) 1996-12-11 2005-05-03 G. D. Searle & Company Processes for preparation of 9, 11-epoxy steroids and intermediates useful therein
EP1223174A3 (en) * 1996-12-11 2005-03-16 G.D. Searle & Co. Processes for preparation of 3-keto-7alpha-alkoxycarbonyl-delta-4,5- steroids and intermediates useful therein
DE69942578D1 (de) 1998-05-22 2010-08-26 Univ R Bifunktionelle moleküle sowie darauf basierende therapien.
AU2002346721A1 (en) 2001-12-12 2003-06-23 Pharmacia Corporation Method of treating ophthalmic disorders with epoxy-steroidal aldosterone receptor antagonists
US7235655B2 (en) 2002-03-22 2007-06-26 Pharmacia & Upjohn Company Processes to prepare eplerenone
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
WO2007025780A2 (en) * 2005-09-02 2007-03-08 Recordati Ireland Limited Aldosterone receptor antagonists
US9062126B2 (en) 2005-09-16 2015-06-23 Raptor Pharmaceuticals Inc. Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
AU2010216512B2 (en) 2009-02-20 2016-06-30 2-Bbb Medicines B.V. Glutathione-based drug delivery system
MY163048A (en) 2009-05-06 2017-08-15 Laboratory Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3013012A (en) * 1960-12-22 1961-12-12 Searle & Co Alkanoylthio-17alpha-carboxyethyl-17beta-hydroxyandrosten-3-one lactones
US3095412A (en) * 1961-12-19 1963-06-25 Searle & Co 9alpha, 11alpha-epoxy and 11beta-chloro-9alpha-hydroxy 17alpha-(2-carboxyethyl)-17beta-hydroxyandrost-4-en-3-one gamma-lactones and delta1 and delta6 analogs
GB1041534A (en) * 1963-04-24 1966-09-07 Merck & Co Inc 20-spiroxane compounds
DE2652761C2 (de) * 1976-11-16 1985-11-21 Schering AG, 1000 Berlin und 4709 Bergkamen 15,16-Methylen-Spirolactone, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
US4559332A (en) * 1983-04-13 1985-12-17 Ciba Geigy Corporation 20-Spiroxanes and analogues having an open ring E, processes for their manufacture, and pharmaceutical preparations thereof
DE3481707D1 (de) * 1983-08-17 1990-04-26 Schering Ag 7-alpha-substituierte 3-oxo-17alpha-pregn-4-en-21.17-carbolactone, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.

Also Published As

Publication number Publication date
EP0165902A3 (en) 1986-10-22
ES544387A0 (es) 1987-04-16
FI83225C (fi) 1991-06-10
FI852430L (fi) 1985-12-22
ES8707737A1 (es) 1987-08-16
NZ212492A (en) 1989-02-24
IE851535L (en) 1985-12-21
IE58050B1 (en) 1993-06-16
ES557112A0 (es) 1987-08-16
EP0165902A2 (de) 1985-12-27
AU582754B2 (en) 1989-04-13
FI852430A0 (fi) 1985-06-19
US4670551A (en) 1987-06-02
AR245731A1 (es) 1994-02-28
ES8704967A1 (es) 1987-04-16
EP0165902B1 (de) 1989-04-19
GR851499B (no) 1985-11-25
DK280085A (da) 1985-12-22
HUT38367A (en) 1986-05-28
HU192232B (en) 1987-05-28
AR242036A1 (es) 1993-02-26
NO165496B (no) 1990-11-12
IL75569A0 (en) 1985-10-31
PT80663B (en) 1987-05-08
DK280085D0 (da) 1985-06-20
IL75569A (en) 1989-03-31
DK173854B1 (da) 2001-12-27
NO165496C (no) 1991-02-20
PT80663A (en) 1985-07-01
CA1239388A (en) 1988-07-19
DE3569540D1 (en) 1989-05-24
AU4397185A (en) 1986-01-02
FI83225B (fi) 1991-02-28

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