NO820957L - Fremgangsmaate for fremstilling av nye oxazafosforin-4-tioalkansulfonsyrer og noeytrale salter derav - Google Patents

Fremgangsmaate for fremstilling av nye oxazafosforin-4-tioalkansulfonsyrer og noeytrale salter derav

Info

Publication number: NO820957L
Authority: NO; Norway
Prior art keywords: tioalcan; phosphorphorin; noeytral; oxaza; salts
Prior art date: 1981-03-24

Application number

NO820957A

Other languages

English (en)

Other versions

NO163692C (no

NO163692B (no

Inventor

Gerhard Scheffler

Ulf Niemeyer

Norbert Brock

Joerg Pohl

Original Assignee

Asta Werke Ag Chem Fab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-03-24

Filing date

1982-03-23

Publication date

1982-09-27

1982-03-23 Application filed by Asta Werke Ag Chem Fab filed Critical Asta Werke Ag Chem Fab

1982-09-27 Publication of NO820957L publication Critical patent/NO820957L/no

1990-03-26 Publication of NO163692B publication Critical patent/NO163692B/no

1990-07-04 Publication of NO163692C publication Critical patent/NO163692C/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
- C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
- C07F9/65846—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

NO820957A 1981-03-24 1982-03-23 Analogifremgangsmaate for fremstilling av terapeutisk aktive oksazafosforin-4-tio-alkansulfonsyrer og salter derav. NO163692C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19813111428 DE3111428A1 (de)	1981-03-24	1981-03-24	Oxazaphosphorin-4-thio-alkansulfonsaeuren und deren neutrale salze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen

Publications (3)

Publication Number	Publication Date
NO820957L true NO820957L (no)	1982-09-27
NO163692B NO163692B (no)	1990-03-26
NO163692C NO163692C (no)	1990-07-04

Family

ID=6128090

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO820957A NO163692C (no)	1981-03-24	1982-03-23	Analogifremgangsmaate for fremstilling av terapeutisk aktive oksazafosforin-4-tio-alkansulfonsyrer og salter derav.

Country Status (31)

Country	Link
US (2)	US4623742A (no)
JP (1)	JPS57169496A (no)
AT (1)	AT381317B (no)
AU (1)	AU544493B2 (no)
BE (1)	BE892589A (no)
BG (1)	BG38489A3 (no)
CA (1)	CA1194479A (no)
CH (1)	CH648852A5 (no)
DD (1)	DD201799A5 (no)
DE (1)	DE3111428A1 (no)
DK (1)	DK171843B1 (no)
EG (1)	EG15703A (no)
ES (1)	ES510677A0 (no)
FI (1)	FI69849C (no)
FR (1)	FR2502626B1 (no)
GB (1)	GB2095256B (no)
GR (1)	GR75533B (no)
HU (1)	HU186915B (no)
IE (1)	IE53054B1 (no)
IL (1)	IL65255A (no)
IT (1)	IT1150499B (no)
LU (1)	LU84032A1 (no)
NL (1)	NL192741C (no)
NO (1)	NO163692C (no)
PL (1)	PL129426B1 (no)
PT (1)	PT74641B (no)
RO (1)	RO84661B (no)
SE (1)	SE452159B (no)
SU (1)	SU1318167A3 (no)
YU (1)	YU61582A (no)
ZA (1)	ZA821637B (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3111428A1 (de) *	1981-03-24	1982-10-07	Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld	Oxazaphosphorin-4-thio-alkansulfonsaeuren und deren neutrale salze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
DE3279834D1 (en) *	1981-12-31	1989-08-31	Asta Pharma Ag	4-sulfido-oxaza phosphorines and their use in the treatment of cancer, and in immunosuppression
DE3569737D1 (en) *	1984-03-01	1989-06-01	Asta Pharma Ag	Salts of oxazaphosphorine derivatives
ZA851062B (en) *	1984-03-01	1985-11-27	Asta Werke Ag Chem Fab	Salts of oxazaphosphorine derivatives and process for their production
DE3415726A1 (de) *	1984-04-27	1985-10-31	Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld	Verfahren zur herstellung von in 4-stellung substituierten oxazaphosphorin-derivaten
FR2567129B1 (fr) *	1984-07-06	1986-12-05	Adir	Nouveaux derives de l'oxaazaphosphorine, leur procede de preparation et les compositions pharmaceutiques les renfermant
US5204335A (en) *	1986-10-31	1993-04-20	Asta Pharma Aktiengesellschaft	Ifosfamide lyophilisate and process for its preparation
ES2040394T3 (es) *	1988-03-19	1993-10-16	Asta Medica Aktiengesellschaft	Procedimiento para preparar un material liofilizado de ifosfamida y mesna.
US5190929A (en) *	1988-05-25	1993-03-02	Research Corporation Technologies, Inc.	Cyclophosphamide analogs useful as anti-tumor agents
RO113611B1 (ro) *	1990-08-03	1998-09-30	Asta Pharma Ag	Preparate solide de ifosfamida, administrate oral si procedeu de obtinere
US5661188A (en) *	1995-06-07	1997-08-26	Medical Research Foundation and Infrastructure Development for Health Services--Nahariya Hospital Branch	Therapeutic uses for sodium 2-mercaptoethanesulphonate (mesna)
US20080223826A1 (en) *	2007-03-13	2008-09-18	Stephen Mazur	Reagent Delivery using a Membrane-Mediated Process
FR2968662B1 (fr) *	2010-12-10	2013-11-22	Roussy Inst Gustave	Nouveaux derives d'oxazaphosphorines pre-activees, utilisation et methode de preparation
GB2626789A (en) *	2023-02-03	2024-08-07	Exactmer Ltd	Deprotection processes and cation scavengers for use in the same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2107936C3 (de) *	1971-02-19	1978-06-08	Asta-Werke Ag Chemische Fabrik, 4800 Bielefeld	Alkylsulfonsäureester von 2-Oxo-13,2-oxazaphosphorinanen und diese enthaltende pharmazeutische Präparate
DE1645921C3 (de) *	1966-07-11	1978-10-12	Asta-Werke Ag Chemische Fabrik, 4800 Bielefeld	2-Oxo-13,2-osazaphosphorinane, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
DE2201675A1 (de) *	1972-01-14	1973-07-19	Asta Werke Ag Chem Fab	Alkylsulfonsaeureester 1,3,2-oxazaphospha-cyclischer verbindungen, verfahren zu ihrer herstellung und pharmazeutische praeparate
JPS5159886A (no) *	1974-11-20	1976-05-25	Shionogi Seiyaku Kk
JPS54157580A (en)	1978-05-29	1979-12-12	Otsuka Pharmaceut Co Ltd	Optically active oxazaphosphorine derivative
JPS5826919B2 (ja)	1978-11-07	1983-06-06	大塚製薬株式会社	シクロ↓−１，３，２↓−オキサアザホスホル誘導体の製造法
JPS55154984A (en) *	1979-05-24	1980-12-02	Shionogi & Co Ltd	Novel 4-substituted-2h-1,3,2-oxaazaphospholine-2-oxide derivative
DE3220432A1 (de)	1981-03-24	1983-12-01	Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld	Oxazaphosphorin-4-thio-alkansulfonsaeure, ihre neutralen salze, verfahren zur herstellung derselben und diese enthaltenden pharmazeutischen praeparate
DE3111428A1 (de)	1981-03-24	1982-10-07	Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld	Oxazaphosphorin-4-thio-alkansulfonsaeuren und deren neutrale salze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
DE3220672A1 (de)	1981-03-24	1983-12-08	Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld	Cis-oxazaphosphorin-4-thio-alkansulfonsaeuren, ihre neutralen salze, verfahren zur herstellung derselben und diese enthaltenden pharmazeutischen praeparate

1981
- 1981-03-24 DE DE19813111428 patent/DE3111428A1/de active Granted
1982
- 1982-03-08 CH CH1390/82A patent/CH648852A5/de not_active IP Right Cessation
- 1982-03-09 IE IE531/82A patent/IE53054B1/en unknown
- 1982-03-11 ZA ZA821637A patent/ZA821637B/xx unknown
- 1982-03-12 AU AU81344/82A patent/AU544493B2/en not_active Ceased
- 1982-03-12 GB GB8207375A patent/GB2095256B/en not_active Expired
- 1982-03-15 IL IL65255A patent/IL65255A/xx unknown
- 1982-03-17 AT AT0106382A patent/AT381317B/de not_active IP Right Cessation
- 1982-03-17 GR GR67621A patent/GR75533B/el unknown
- 1982-03-22 RO RO106989A patent/RO84661B/ro unknown
- 1982-03-22 FR FR8204823A patent/FR2502626B1/fr not_active Expired
- 1982-03-22 SE SE8201807A patent/SE452159B/sv not_active IP Right Cessation
- 1982-03-22 YU YU00615/82A patent/YU61582A/xx unknown
- 1982-03-23 BE BE2/59642A patent/BE892589A/fr not_active IP Right Cessation
- 1982-03-23 DK DK129882A patent/DK171843B1/da not_active IP Right Cessation
- 1982-03-23 ES ES510677A patent/ES510677A0/es active Granted
- 1982-03-23 SU SU823414100A patent/SU1318167A3/ru active
- 1982-03-23 NO NO820957A patent/NO163692C/no not_active IP Right Cessation
- 1982-03-23 CA CA000399098A patent/CA1194479A/en not_active Expired
- 1982-03-23 JP JP57044779A patent/JPS57169496A/ja active Granted
- 1982-03-23 HU HU82879A patent/HU186915B/hu unknown
- 1982-03-23 EG EG82156A patent/EG15703A/xx active
- 1982-03-23 FI FI821021A patent/FI69849C/fi not_active IP Right Cessation
- 1982-03-23 IT IT20351/82A patent/IT1150499B/it active
- 1982-03-23 PT PT74641A patent/PT74641B/pt unknown
- 1982-03-23 DD DD82238374A patent/DD201799A5/de unknown
- 1982-03-24 LU LU84032A patent/LU84032A1/de unknown
- 1982-03-24 NL NL8201227A patent/NL192741C/nl not_active IP Right Cessation
- 1982-03-24 BG BG055941A patent/BG38489A3/xx unknown
- 1982-08-24 PL PL1982235606A patent/PL129426B1/pl unknown
1984
- 1984-12-19 US US06/683,374 patent/US4623742A/en not_active Expired - Lifetime
1988
- 1988-02-02 US US07/149,954 patent/US4929607A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DK171843B1 (da)	1997-06-30
EG15703A (en)	1986-06-30
RO84661A (ro)	1984-10-31
FI69849B (fi)	1985-12-31
SU1318167A3 (ru)	1987-06-15
PT74641A (de)	1982-04-01
FR2502626A1 (fr)	1982-10-01
AT381317B (de)	1986-09-25
DD201799A5 (de)	1983-08-10
IL65255A (en)	1986-03-31
RO84661B (ro)	1984-11-30
PL129426B1 (en)	1984-05-31
ATA106382A (de)	1986-02-15
YU61582A (en)	1985-03-20
IE53054B1 (en)	1988-05-25
ZA821637B (en)	1983-02-23
DE3111428C2 (no)	1990-06-13
BE892589A (fr)	1982-07-16
JPH0240680B2 (no)	1990-09-12
PT74641B (de)	1983-10-20
DE3111428A1 (de)	1982-10-07
GB2095256B (en)	1984-08-22
FI69849C (fi)	1986-05-26
IT8220351A0 (it)	1982-03-23
FI821021A0 (fi)	1982-03-23
HU186915B (en)	1985-10-28
NL8201227A (nl)	1982-10-18
NL192741C (nl)	1998-01-06
NO163692C (no)	1990-07-04
IT1150499B (it)	1986-12-10
JPS57169496A (en)	1982-10-19
ES8303440A1 (es)	1983-02-01
IE820531L (en)	1982-09-24
US4623742A (en)	1986-11-18
IL65255A0 (en)	1982-05-31
AU8134482A (en)	1982-09-30
SE8201807L (sv)	1982-09-25
US4929607A (en)	1990-05-29
BG38489A3 (en)	1985-12-16
FR2502626B1 (fr)	1986-01-03
CA1194479A (en)	1985-10-01
LU84032A1 (de)	1982-07-08
CH648852A5 (de)	1985-04-15
FI821021L (fi)	1982-09-25
ES510677A0 (es)	1983-02-01
AU544493B2 (en)	1985-05-30
GB2095256A (en)	1982-09-29
DK129882A (da)	1982-09-25
PL235606A1 (no)	1982-11-08
GR75533B (no)	1984-07-27
NO163692B (no)	1990-03-26
NL192741B (nl)	1997-09-01
SE452159B (sv)	1987-11-16

Publication	Publication Date	Title
NO820287L (no)	1982-08-04	Fremgangsmaate for fremstilling av isocyanursyre-derivater
NO821767L (no)	1982-12-02	Fremgangsmaate for fremstilling av nye benzotiazin-dioksyd-salter
ES512815A0 (es)	1983-08-01	"procedimiento para la preparacion de mandelonitrilos y derivados de acido mandelico".
NO820957L (no)	1982-09-27	Fremgangsmaate for fremstilling av nye oxazafosforin-4-tioalkansulfonsyrer og noeytrale salter derav
NO821595L (no)	1982-11-19	Fremgangsmaate for fremstilling av 2-(2-benzyl-3-merkapto-propionylamino)-derivater av 1-alkanoler og av 4-metyltiosmoersyre
NO862141L (no)	1986-12-01	Fremgangsmaate for fremstilling av aktive cinnolinderivater
NO844978L (no)	1985-06-13	Fremgangsmaate ved fremstilling av nye aminoguanidinderivater
NO860857L (no)	1986-09-09	Nye oksadiazolyl-imidazobenzodiazepin-derivater og fremgangsmaate for fremstilling av slike forbindelser.
PT75636A (en)	1982-11-01	Method for the preparation of 3-phenyl-1-indamines isomers thereof and acid addition salts
IT1128163B (it)	1986-05-28	Procedimento per la preparazione di acidi alcanoici
IT1110819B (it)	1986-01-06	Procedimento per la preparazione di acidi benzen-carbossilici
NO842078L (no)	1984-11-26	Fremgangsmaate for fremstilling av nye aryloxycycloalkanol-aminoalkylenarylketoner
NO864818D0 (no)	1986-12-01	Fremgangsmaate for fremstilling av nye terapeutisk virksomme tetrahydroisokinolinderivater.
NO863834L (no)	1987-03-27	Fremgangsmaate for fremstilling av nye katekolderivater.
NO891919L (no)	1989-11-13	Fremgangsmaate for fremstilling av nye karboksylsyrederivater.
ES529565A0 (es)	1986-04-16	Procedimiento de preparacion de eteres oximas basicos, y de sus sales de adicion acidas farmaceuticamente aceptables
NO151858C (no)	1985-06-19	Fremgangsmaate for fremstilling av d-2-(6-metoksy-2-naftyl)-propionsyre eller farmasoeytisk akseptable salter derav
NO893006D0 (no)	1989-07-21	Fremgangsmaate for fremstilling av nye allylaminoetylazoler
IT1198399B (it)	1988-12-21	Procedimento di preparazione di acidi fenossibenzoici
NO851620L (no)	1985-10-25	Fremgangsmaate for fremstilling av nye bornan-derivater
IT1132221B (it)	1986-06-25	Procedimento per la preparazione di acidi fenossiacetici
SE8200271L (sv)	1982-09-28	Nytt forfarande for framstellning av imidazobensodiazepiner samt deras salter
NO884901D0 (no)	1988-11-03	Fremgangsmaate for fremstilling av nye indenofuranderivater
NO882564L (no)	1988-12-13	Fremgangsmaate for fremstilling av nye aminoacylater av glycerolacetal.
NO892692D0 (no)	1989-06-28	Fremgangsmaate for fremstilling av 5-fluornikotinsyre-derivater og salter derav eller 2-(5-fluornikotinoyl) - eddiksyrederivater.

Legal Events

Date	Code	Title	Description
2002-05-13	MK1K	Patent expired	Free format text: EXPIRED IN MARCH 2002