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NO321455B1 - Anvendelse av en forbindelse som inhiberer bindingen av faktor AP1 til sekvens SEQ ID Nr. 1 til fremstilling av et medikament til behandling av og/eller forebygging av neurodegenerative lidelser. - Google Patents

Anvendelse av en forbindelse som inhiberer bindingen av faktor AP1 til sekvens SEQ ID Nr. 1 til fremstilling av et medikament til behandling av og/eller forebygging av neurodegenerative lidelser. Download PDF

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Publication number
NO321455B1
NO321455B1 NO19954888A NO954888A NO321455B1 NO 321455 B1 NO321455 B1 NO 321455B1 NO 19954888 A NO19954888 A NO 19954888A NO 954888 A NO954888 A NO 954888A NO 321455 B1 NO321455 B1 NO 321455B1
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Norway
Prior art keywords
sequence seq
binding
nucleic acid
factor
vims
Prior art date
Application number
NO19954888A
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English (en)
Norwegian (no)
Other versions
NO954888D0 (no
NO954888L (no
Inventor
Jacques Mallet
Jean-Jacques Robert
Frederic Revah
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of NO954888D0 publication Critical patent/NO954888D0/no
Publication of NO954888L publication Critical patent/NO954888L/no
Publication of NO321455B1 publication Critical patent/NO321455B1/no

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1135Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82Translation products from oncogenes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/11Antisense
    • C12N2310/111Antisense spanning the whole gene, or a large part of it
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/13Decoys

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
NO19954888A 1993-06-30 1995-12-01 Anvendelse av en forbindelse som inhiberer bindingen av faktor AP1 til sekvens SEQ ID Nr. 1 til fremstilling av et medikament til behandling av og/eller forebygging av neurodegenerative lidelser. NO321455B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9307962A FR2707880B1 (fr) 1993-06-30 1993-06-30 Compositions pharmaceutiques et leur utilisation, notamment pour le traitement des maladies neurodégénératives.
PCT/FR1994/000771 WO1995001429A1 (fr) 1993-06-30 1994-06-27 Compositions pharmaceutiques et leur utilisation, notamment pour le traitement des maladies neurodegeneratives

Publications (3)

Publication Number Publication Date
NO954888D0 NO954888D0 (no) 1995-12-01
NO954888L NO954888L (no) 1995-12-01
NO321455B1 true NO321455B1 (no) 2006-05-15

Family

ID=9448720

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19954888A NO321455B1 (no) 1993-06-30 1995-12-01 Anvendelse av en forbindelse som inhiberer bindingen av faktor AP1 til sekvens SEQ ID Nr. 1 til fremstilling av et medikament til behandling av og/eller forebygging av neurodegenerative lidelser.

Country Status (15)

Country Link
US (1) US6140112A (sv)
EP (2) EP0707644B1 (sv)
JP (1) JP3755825B2 (sv)
KR (1) KR100517879B1 (sv)
AT (1) ATE276360T1 (sv)
AU (1) AU696644B2 (sv)
CA (1) CA2166318C (sv)
DE (1) DE69433996T2 (sv)
DK (1) DK0707644T3 (sv)
ES (1) ES2227528T3 (sv)
FI (1) FI120942B (sv)
FR (1) FR2707880B1 (sv)
NO (1) NO321455B1 (sv)
PT (1) PT707644E (sv)
WO (1) WO1995001429A1 (sv)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
US5824662A (en) 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
NZ334780A (en) 1996-09-27 2000-12-22 Guilford Pharm Inc Use of a NAALADase inhibitor for treating glutamate abnormality and effecting neuronal activity in animals
US6599741B1 (en) 1999-09-14 2003-07-29 Avontec Gmbh Modulating transcription of genes in vascular cells
DE29916160U1 (de) 1999-09-14 2000-03-09 Cardiogene Gentherapeutische Systeme AG, 40699 Erkrath Modulation der Transkription von Genen in vaskulären Zellen
CN1315402A (zh) * 2000-03-28 2001-10-03 上海博德基因开发有限公司 一种新的多肽——人淀粉类前体蛋白结合蛋白14和编码这种多肽的多核苷酸
CN1315439A (zh) * 2000-03-29 2001-10-03 上海博德基因开发有限公司 一种新的多肽——人淀粉类前体蛋白结合蛋白9和编码这种多肽的多核苷酸
DE10308045B3 (de) 2003-02-26 2004-06-17 Lurgi Ag Verfahren und Vorrichtung zur kontinuierlichen Gewinnung freier Weinsäure aus Kaliumhydrogentartrat enthaltenden Rohstoffen

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2573436B1 (fr) * 1984-11-20 1989-02-17 Pasteur Institut Adn recombinant comportant une sequence nucleotidique codant pour un polypeptide determine sous le controle d'un promoteur d'adenovirus, vecteurs contenant cet adn recombinant, cellules eucaryotes transformees par cet adn recombinant, produits d'excretion de ces cellules transformees et leurs applications, notamment a la constitution de vaccins
WO1991011535A1 (en) * 1990-01-30 1991-08-08 Childrens Hospital Of Los Angeles Inhibition of transcription by double-stranded oligonucleotides
WO1991018088A1 (en) * 1990-05-23 1991-11-28 The United States Of America, Represented By The Secretary, United States Department Of Commerce Adeno-associated virus (aav)-based eucaryotic vectors
FR2675803B1 (fr) * 1991-04-25 1996-09-06 Genset Sa Oligonucleotides fermes, antisens et sens et leurs applications.
GB9114437D0 (en) * 1991-07-03 1991-08-21 Health Lab Service Board Recombinant adenoviruses and the use thereof for detecting the presence in eukaryotic cells of the expression products of specific genes
FR2708283B1 (fr) * 1994-01-14 1995-10-20 Rhone Poulenc Rorer Sa Compositions pharmaceutiques et leur utilisation, notamment pour le traitement des maladies neurodégénératives.

Also Published As

Publication number Publication date
DE69433996D1 (de) 2004-10-21
FR2707880A1 (fr) 1995-01-27
NO954888D0 (no) 1995-12-01
EP0707644A1 (fr) 1996-04-24
ATE276360T1 (de) 2004-10-15
AU7188294A (en) 1995-01-24
JPH08512043A (ja) 1996-12-17
DK0707644T3 (da) 2005-01-17
NO954888L (no) 1995-12-01
FR2707880B1 (fr) 1995-10-06
EP0707644B1 (fr) 2004-09-15
ES2227528T3 (es) 2005-04-01
JP3755825B2 (ja) 2006-03-15
KR960703432A (ko) 1996-08-17
FI956353L (sv) 1995-12-29
WO1995001429A1 (fr) 1995-01-12
FI956353A0 (sv) 1995-12-29
AU696644B2 (en) 1998-09-17
FI120942B (sv) 2010-05-14
CA2166318C (fr) 2009-02-10
EP1454984A1 (fr) 2004-09-08
KR100517879B1 (ko) 2005-12-16
PT707644E (pt) 2005-01-31
CA2166318A1 (fr) 1995-01-12
US6140112A (en) 2000-10-31
DE69433996T2 (de) 2005-09-22

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