NO306509B1 - Pyrimidinderivater, anvendelse derav og farmasöytisk preparat - Google Patents

Pyrimidinderivater, anvendelse derav og farmasöytisk preparat

Info

Publication number: NO306509B1
Authority: NO; Norway
Prior art keywords: alkyl; halo; cyano; hydroxy; optionally substituted
Prior art date: 1993-10-13

Application number

NO961435A

Other languages

English (en)

Norwegian (no)

Other versions

NO961435D0 (no

NO961435L (no

Inventor

David John Heal

Marya Isabel Fernand Fernandes

Bruce Jeremy Sargent

Original Assignee

Knoll Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-10-13

Filing date

1996-04-11

Publication date

1999-11-15

1996-04-11 Application filed by Knoll Ag filed Critical Knoll Ag

1996-04-11 Publication of NO961435D0 publication Critical patent/NO961435D0/no

1996-06-10 Publication of NO961435L publication Critical patent/NO961435L/no

1999-11-15 Publication of NO306509B1 publication Critical patent/NO306509B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Steroid Compounds (AREA)

NO961435A 1993-10-13 1996-04-11 Pyrimidinderivater, anvendelse derav og farmasöytisk preparat NO306509B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB939321162A GB9321162D0 (en)	1993-10-13	1993-10-13	Therapeutic agents
PCT/EP1994/003364 WO1995010521A1 (en)	1993-10-13	1994-10-12	Therapeutic agents

Publications (3)

Publication Number	Publication Date
NO961435D0 NO961435D0 (no)	1996-04-11
NO961435L NO961435L (no)	1996-06-10
NO306509B1 true NO306509B1 (no)	1999-11-15

Family

ID=10743505

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO961435A NO306509B1 (no)	1993-10-13	1996-04-11	Pyrimidinderivater, anvendelse derav og farmasöytisk preparat

Country Status (31)

Country	Link
US (1)	US5753665A (bg)
EP (1)	EP0723546B1 (bg)
JP (1)	JPH09503771A (bg)
CN (1)	CN1040537C (bg)
AT (1)	ATE188966T1 (bg)
AU (1)	AU679573B2 (bg)
BG (1)	BG62405B1 (bg)
BR (1)	BR9407812A (bg)
CA (1)	CA2173857A1 (bg)
CZ (1)	CZ106996A3 (bg)
DE (1)	DE69422724T2 (bg)
DK (1)	DK0723546T3 (bg)
ES (1)	ES2142413T3 (bg)
FI (1)	FI961630A (bg)
GB (1)	GB9321162D0 (bg)
GR (1)	GR3032480T3 (bg)
HU (1)	HUT74580A (bg)
IL (1)	IL111259A (bg)
IN (1)	IN179169B (bg)
MY (1)	MY112110A (bg)
NO (1)	NO306509B1 (bg)
NZ (1)	NZ274500A (bg)
PL (1)	PL177920B1 (bg)
PT (1)	PT723546E (bg)
RO (1)	RO117020B1 (bg)
RU (1)	RU2136684C1 (bg)
SK (1)	SK282329B6 (bg)
TW (1)	TW372237B (bg)
UA (1)	UA42738C2 (bg)
WO (1)	WO1995010521A1 (bg)
ZA (1)	ZA947949B (bg)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9506382D0 (en) *	1995-03-29	1995-05-17	Boots Co Plc	Pharmaceutical compositions
GB9507348D0 (en) *	1995-04-08	1995-05-31	Knoll Ag	Therapeutic agents
US5714607A (en) *	1995-12-01	1998-02-03	American Cyanamid Company	Process improvement in the synthesis of N- 3-(3-cyano-pyrazolo 1,5-a!pyrimidin-7-yl)phenyl!-N-ethylacetamide
EP0915875B1 (en) *	1996-07-25	2003-04-09	MERCK SHARP & DOHME LTD.	Substituted triazolo-pyridazine derivatives as ligands for gaba receptors
GB9617727D0 (en) *	1996-08-23	1996-10-02	Knoll Ag	Process
GB9626746D0 (en) *	1996-12-23	1997-02-12	Knoll Ag	Process
DE19706337A1 (de) *	1997-02-19	1998-08-20	Basf Ag	Verfahren zur Herstellung von enantiomerenreinen Estern
DE19706336A1 (de) *	1997-02-19	1998-08-20	Basf Ag	Verfahren zur Herstellung von enantiomerenreinen Alkoholen
DE19707008A1 (de) *	1997-02-21	1998-08-27	Basf Ag	Verfahren zur Herstellung von enantiomerenreinen Alkoholen
AU760688B2 (en)	1998-10-16	2003-05-22	Merck Sharp & Dohme Limited	Pyrazolo-triazine derivatives as ligands for GABA receptors
GB9906130D0 (en) *	1999-03-18	1999-05-12	Knoll Ag	Compounds for use in therapy
GB9906124D0 (en) *	1999-03-18	1999-05-12	Knoll Ag	Therapeutic agent
GB9906126D0 (en) *	1999-03-18	1999-05-12	Knoll Ag	Pharmaceutical formulations
GB9914743D0 (en) *	1999-06-24	1999-08-25	Knoll Ag	Therapeutic agents
AU7306201A (en) *	2000-06-30	2002-01-14	American Home Prod	Substituted-triazolopyrimidines as anticancer agents
WO2005080320A1 (en)	2004-02-13	2005-09-01	Warner-Lambert Company Llc	Androgen receptor modulators
EP1737813A1 (en)	2004-04-13	2007-01-03	Warner-Lambert Company LLC	Androgen modulators
EP1740533A1 (en)	2004-04-22	2007-01-10	Warner-Lambert Company LLC	Androgen modulators
TW200724139A (en)	2005-05-05	2007-07-01	Warner Lambert Co	Androgen modulators
PT2328414E (pt) *	2008-08-29	2014-03-17	Concert Pharmaceuticals Inc	Derivados de triazol-piridazina substituídos
WO2010112485A1 (en)	2009-04-01	2010-10-07	Neurosearch A/S	SUBSTITUTED [1,2,4]TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS
WO2010112486A1 (en) *	2009-04-01	2010-10-07	Neurosearch A/S	SUBSTITUTED [1,2,4]TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS
EP2414364A1 (en) *	2009-04-01	2012-02-08	NeuroSearch A/S	SUBSTITUTED Ý1,2,4¨TRIAZOLOÝ1,5-a¨PYRIMIDINES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS
CA3138307A1 (en)	2019-05-13	2020-11-19	Ecolab Usa Inc.	1,2,4-triazolo[1,5-a] pyrimidine derivative as copper corrosion inhibitor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE46306B1 (en) *	1977-02-11	1983-05-04	Ici Ltd	Safeguarded toxic chemical compositions containing an emetic
WO1989001478A1 (en) *	1987-08-07	1989-02-23	The Australian National University	ARYLOXY- AND ARALKYLTHIO-IMIDAZO[1,2-b]PYRIDAZINES
US5387747A (en) *	1992-02-24	1995-02-07	Laboratoires Upsa	Triazolopyrimidine derivatives which are angiotensin II receptor antagonists, their methods of preparation and pharmaceutical compositions in which they are present

1993
- 1993-10-13 GB GB939321162A patent/GB9321162D0/en active Pending
1994
- 1994-10-11 IN IN982MA1994 patent/IN179169B/en unknown
- 1994-10-12 US US08/628,662 patent/US5753665A/en not_active Expired - Lifetime
- 1994-10-12 DK DK94929537T patent/DK0723546T3/da active
- 1994-10-12 DE DE69422724T patent/DE69422724T2/de not_active Expired - Lifetime
- 1994-10-12 ZA ZA947949A patent/ZA947949B/xx unknown
- 1994-10-12 CN CN94194265A patent/CN1040537C/zh not_active Expired - Fee Related
- 1994-10-12 RO RO96-00795A patent/RO117020B1/ro unknown
- 1994-10-12 RU RU96108927A patent/RU2136684C1/ru active
- 1994-10-12 HU HU9600959A patent/HUT74580A/hu unknown
- 1994-10-12 BR BR9407812A patent/BR9407812A/pt not_active Application Discontinuation
- 1994-10-12 WO PCT/EP1994/003364 patent/WO1995010521A1/en not_active Application Discontinuation
- 1994-10-12 CA CA002173857A patent/CA2173857A1/en not_active Abandoned
- 1994-10-12 EP EP94929537A patent/EP0723546B1/en not_active Expired - Lifetime
- 1994-10-12 SK SK437-96A patent/SK282329B6/sk unknown
- 1994-10-12 ES ES94929537T patent/ES2142413T3/es not_active Expired - Lifetime
- 1994-10-12 AU AU78554/94A patent/AU679573B2/en not_active Ceased
- 1994-10-12 JP JP7511287A patent/JPH09503771A/ja not_active Ceased
- 1994-10-12 IL IL111259A patent/IL111259A/en not_active IP Right Cessation
- 1994-10-12 UA UA96041428A patent/UA42738C2/uk unknown
- 1994-10-12 AT AT94929537T patent/ATE188966T1/de not_active IP Right Cessation
- 1994-10-12 NZ NZ274500A patent/NZ274500A/en unknown
- 1994-10-12 PL PL94313970A patent/PL177920B1/pl unknown
- 1994-10-12 PT PT94929537T patent/PT723546E/pt unknown
- 1994-10-12 CZ CZ961069A patent/CZ106996A3/cs unknown
- 1994-10-13 MY MYPI94002724A patent/MY112110A/en unknown
1995
- 1995-04-12 TW TW084103591A patent/TW372237B/zh active
1996
- 1996-04-09 BG BG100485A patent/BG62405B1/bg unknown
- 1996-04-11 NO NO961435A patent/NO306509B1/no not_active IP Right Cessation
- 1996-04-12 FI FI961630A patent/FI961630A/fi unknown
2000
- 2000-01-26 GR GR20000400175T patent/GR3032480T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
IL111259A0 (en)	1995-03-30
EP0723546B1 (en)	2000-01-19
CN1135754A (zh)	1996-11-13
DE69422724T2 (de)	2000-09-07
MY112110A (en)	2001-04-30
PL177920B1 (pl)	2000-01-31
ZA947949B (en)	1996-01-23
BG62405B1 (bg)	1999-10-29
AU7855494A (en)	1995-05-04
BR9407812A (pt)	1997-05-06
RO117020B1 (ro)	2001-09-28
CZ106996A3 (en)	1996-09-11
HUT74580A (en)	1997-01-28
PT723546E (pt)	2000-04-28
NZ274500A (en)	1997-06-24
NO961435D0 (no)	1996-04-11
US5753665A (en)	1998-05-19
AU679573B2 (en)	1997-07-03
DK0723546T3 (da)	2000-05-01
IL111259A (en)	1998-02-08
DE69422724D1 (de)	2000-02-24
CA2173857A1 (en)	1995-04-20
FI961630A0 (fi)	1996-04-12
ES2142413T3 (es)	2000-04-16
SK43796A3 (en)	1996-10-02
NO961435L (no)	1996-06-10
GR3032480T3 (en)	2000-05-31
PL313970A1 (en)	1996-08-05
EP0723546A1 (en)	1996-07-31
UA42738C2 (uk)	2001-11-15
BG100485A (bg)	1996-11-29
JPH09503771A (ja)	1997-04-15
GB9321162D0 (en)	1993-12-01
WO1995010521A1 (en)	1995-04-20
SK282329B6 (sk)	2002-01-07
HU9600959D0 (en)	1996-06-28
IN179169B (bg)	1997-09-06
FI961630A (fi)	1996-04-12
ATE188966T1 (de)	2000-02-15
TW372237B (en)	1999-10-21
RU2136684C1 (ru)	1999-09-10
CN1040537C (zh)	1998-11-04

Publication	Publication Date	Title
NO306509B1 (no)	1999-11-15	Pyrimidinderivater, anvendelse derav og farmasöytisk preparat
DE69209395D1 (de)	1996-05-02	Therapeutische Amide
IL118836A0 (en)	1996-10-31	Pharmaceutical compositions comprising S-(-)N-propargyl-1-aminoindan
PL309347A1 (en)	1995-10-02	Application of anticonvulsive agents in therapy of neurological damages caused by or associated with injuries
NO951797L (no)	1995-05-24	Terapeutiske midler
GEP20033029B (en)	2003-07-25	Substituted 1,8-Naphthyridin-4(1H)-Ones as Phosphodiesterase 4 Inhibitors
MXPA04000278A (es)	2004-05-04	Uso de antagonistas del receptor nk-1 con estructura piridinica para tratamiento de lesiones cerebrales, espinales o neuronales.
CA2148194A1 (en)	1995-10-31	Cyclopeptides of the formula i
GB9305295D0 (en)	1993-05-05	Therapeutic compounds
PL313941A1 (en)	1996-08-05	Alkoxyalkyl carbamates of imidazo /1,2-a/ pyrimidines
GB9418912D0 (en)	1994-11-09	Pharmaceutically active compounds
EP0572635A4 (fr)	1993-09-17	Nouveaux composes a structure guanidique et composition pharmaceutique les contenant.
AR032653A1 (es)	2003-11-19	Inhibidores heterociclicos del trasportador de glicina 2 composiciones farmaceuticas, uso y metodos.
NO305165B1 (no)	1999-04-12	1-Arylcykloalkylsulfider, -sulfoksyder og -sulfoner, farmas°ytiske preparater og anvendelse derav
TW359667B (en)	1999-06-01	Tetralines
JO1833B1 (en)	1995-07-05	Therapeutic agents
MXPA01009384A (es)	2004-03-19	Composiciones farmaceuticas que comprenden un derivado de pirimidina y ciclodextrina.
WO2001032650A3 (en)	2002-05-10	Alkaline salts of n-(6-alkyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinesulfone)-n'-isonicotinoylhydrazide, possess for their preparation, and pharmaceutical composition based on these salts

Legal Events

Date	Code	Title	Description
2003-06-02	MM1K	Lapsed by not paying the annual fees	Free format text: LAPSED IN APRIL 2003