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NO20074742L - Farmakokinetisk forbedrede forbindelser - Google Patents

Farmakokinetisk forbedrede forbindelser

Info

Publication number
NO20074742L
NO20074742L NO20074742A NO20074742A NO20074742L NO 20074742 L NO20074742 L NO 20074742L NO 20074742 A NO20074742 A NO 20074742A NO 20074742 A NO20074742 A NO 20074742A NO 20074742 L NO20074742 L NO 20074742L
Authority
NO
Norway
Prior art keywords
improved compounds
pharmacokinetically improved
pharmacokinetically
improved
compounds
Prior art date
Application number
NO20074742A
Other languages
English (en)
Inventor
David Duffy
Michael Grogan
Steven Kates
Emanuele Ostuni
Olivier Schueller
Paul Sweetnam
Stewart Campbell
Original Assignee
Surface Logix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Surface Logix Inc filed Critical Surface Logix Inc
Publication of NO20074742L publication Critical patent/NO20074742L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

En forbindelse med formel A med forbedrede egenskaper når det gjelder uspesifikk binding og forbedrede farmakokinetiske egenskaper eller et farmasøytisk aksepterbart salt, en stereoisomer eller et hydrat derav tilveiebringes, hvori A, B, D, E og substituentene R1-R3 er som beskrevet i søknaden .
NO20074742A 2005-02-18 2007-09-17 Farmakokinetisk forbedrede forbindelser NO20074742L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65393305P 2005-02-18 2005-02-18
PCT/US2006/006048 WO2006089276A2 (en) 2005-02-18 2006-02-21 Pharmacokinetically improved compounds

Publications (1)

Publication Number Publication Date
NO20074742L true NO20074742L (no) 2007-11-16

Family

ID=36917159

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20074742A NO20074742L (no) 2005-02-18 2007-09-17 Farmakokinetisk forbedrede forbindelser

Country Status (19)

Country Link
US (2) US20080176844A1 (no)
EP (1) EP1850853A4 (no)
JP (1) JP2008530247A (no)
KR (1) KR20080016531A (no)
CN (2) CN101223171B (no)
AU (1) AU2006213985C1 (no)
BR (1) BRPI0608381A2 (no)
CA (1) CA2598271A1 (no)
CR (1) CR9381A (no)
EA (1) EA018668B1 (no)
GE (1) GEP20115184B (no)
IL (1) IL185344A0 (no)
MX (1) MX2007010144A (no)
NI (1) NI200700210A (no)
NO (1) NO20074742L (no)
NZ (1) NZ560963A (no)
UA (1) UA90502C2 (no)
WO (1) WO2006089276A2 (no)
ZA (1) ZA200707505B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA95604C2 (ru) * 2005-02-18 2011-08-25 Сьёрфейс Лоджикс, Инк. Способ регулирования фармакокинетического и/или фармакодинамического свойства соединения
CR9465A (es) * 2005-03-25 2008-06-19 Surface Logix Inc Compuestos mejorados farmacocineticamente
EP2370080A1 (en) * 2008-12-02 2011-10-05 University of Utah Research Foundation Pde1 as a target therapeutic in heart disease

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* Cited by examiner, † Cited by third party
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CH445129A (fr) * 1964-04-29 1967-10-15 Nestle Sa Procédé pour la préparation de composés d'inclusion à poids moléculaire élevé
US3459731A (en) * 1966-12-16 1969-08-05 Corn Products Co Cyclodextrin polyethers and their production
US3453257A (en) * 1967-02-13 1969-07-01 Corn Products Co Cyclodextrin with cationic properties
US3426011A (en) * 1967-02-13 1969-02-04 Corn Products Co Cyclodextrins with anionic properties
US3453259A (en) * 1967-03-22 1969-07-01 Corn Products Co Cyclodextrin polyol ethers and their oxidation products
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4631211A (en) * 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
US4737323A (en) * 1986-02-13 1988-04-12 Liposome Technology, Inc. Liposome extrusion method
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
KR0166088B1 (ko) * 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5359115A (en) * 1992-03-26 1994-10-25 Affymax Technologies, N.V. Methods for the synthesis of phosphonate esters
US5288514A (en) * 1992-09-14 1994-02-22 The Regents Of The University Of California Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
US5480971A (en) * 1993-06-17 1996-01-02 Houghten Pharmaceuticals, Inc. Peralkylated oligopeptide mixtures
US5440016A (en) * 1993-06-18 1995-08-08 Torrey Pines Institute For Molecular Studies Peptides of the formula (KFmoc) ZZZ and their uses
US5362899A (en) * 1993-09-09 1994-11-08 Affymax Technologies, N.V. Chiral synthesis of alpha-aminophosponic acids
CH693954A5 (de) * 1997-11-12 2004-05-14 Bayer Ag 2-Phenyl-substituierte Imidazotriazinone als Phosphodiesterase Inhibitoren.
US5958886A (en) * 1998-01-13 1999-09-28 Sigma-Tau Pharmaceuticals, Inc. Carnitine-containing peptides and a method for using the same
DE19827640A1 (de) * 1998-06-20 1999-12-23 Bayer Ag 7-Alkyl- und Cycloalkyl-substituierte Imidazotriazinone
KR100353014B1 (ko) * 1998-11-11 2002-09-18 동아제약 주식회사 발기부전 치료에 효과를 갖는 피라졸로피리미디논 화합물
GB9924020D0 (en) * 1999-10-11 1999-12-15 Pfizer Ltd Pharmaceutically active compounds
CA2323008C (en) * 1999-10-11 2005-07-12 Pfizer Inc. Pharmaceutically active compounds
CN1434825A (zh) * 1999-12-24 2003-08-06 拜尔公司 咪唑并[1,3,5]三嗪酮及其应用
DE50008549D1 (de) * 1999-12-24 2004-12-09 Bayer Healthcare Ag Triazolotriazinone und ihre verwendung
US6548508B2 (en) * 2000-10-20 2003-04-15 Pfizer, Inc. Use of PDE V inhibitors for improved fecundity in mammals
DE10107639A1 (de) * 2001-02-15 2002-08-22 Bayer Ag 2-Alkoxyphenyl-substituierte Imidazotriazinone
GB0106661D0 (en) * 2001-03-16 2001-05-09 Pfizer Ltd Pharmaceutically active compounds
US6794387B2 (en) * 2001-03-28 2004-09-21 Pfizer Inc. Pharmaceutically active compounds

Also Published As

Publication number Publication date
CN101223171B (zh) 2011-09-14
CR9381A (es) 2008-06-19
CA2598271A1 (en) 2006-08-24
ZA200707505B (en) 2009-08-26
EA018668B1 (ru) 2013-09-30
UA90502C2 (ru) 2010-05-11
NI200700210A (es) 2008-07-24
EP1850853A4 (en) 2011-09-07
KR20080016531A (ko) 2008-02-21
AU2006213985C1 (en) 2012-03-15
WO2006089276A2 (en) 2006-08-24
US20080176844A1 (en) 2008-07-24
BRPI0608381A2 (pt) 2009-12-29
EP1850853A2 (en) 2007-11-07
GEP20115184B (en) 2011-03-25
AU2006213985A1 (en) 2006-08-24
CN102351862A (zh) 2012-02-15
JP2008530247A (ja) 2008-08-07
IL185344A0 (en) 2008-02-09
US20100093719A1 (en) 2010-04-15
WO2006089276A3 (en) 2006-12-21
MX2007010144A (es) 2008-02-15
EA200701753A1 (ru) 2008-04-28
CN101223171A (zh) 2008-07-16
AU2006213985B2 (en) 2011-08-25
NZ560963A (en) 2010-11-26

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application