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NO20073294L - G-proteinkoplet reseptor - Google Patents

G-proteinkoplet reseptor

Info

Publication number
NO20073294L
NO20073294L NO20073294A NO20073294A NO20073294L NO 20073294 L NO20073294 L NO 20073294L NO 20073294 A NO20073294 A NO 20073294A NO 20073294 A NO20073294 A NO 20073294A NO 20073294 L NO20073294 L NO 20073294L
Authority
NO
Norway
Prior art keywords
gpr39
protein
relates
compounds
coupled receptor
Prior art date
Application number
NO20073294A
Other languages
English (en)
Inventor
Diederik Willem Elisa Moechars
Benoit Christian Jean- Moreaux
Theophiel Louis Henri Peeters
Inge Irma Therese Depoortere
Bernard Coulie
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO20073294L publication Critical patent/NO20073294L/no

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Foreliggende oppfinnelse vedrører den funksjonelle karakterisering av den G-protein-koblede reseptor GPR39, og forbindelser som modifiserer eller regulerer GPR39-proteinaktivitet. Spesielt vedrører foreliggende oppfinnelse fremgangsmåter for å teste med hensyn til agonister eller antagonister av GPR39 for å identifisere forbindelser som har evnen til å modulere mage/tarm-kinetikken og/eller kolesterolmetabolismen, og terapeutiske anvendelser av disse forbindelser. Oppfinnelsen vedrører også transgene dyr som bærer mutasjoner i GPR39-genet.
NO20073294A 2004-12-01 2007-06-28 G-proteinkoplet reseptor NO20073294L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04106220 2004-12-01
PCT/EP2005/056350 WO2006058889A1 (en) 2004-12-01 2005-11-30 G protein coupled receptor

Publications (1)

Publication Number Publication Date
NO20073294L true NO20073294L (no) 2007-08-29

Family

ID=34929976

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20073294A NO20073294L (no) 2004-12-01 2007-06-28 G-proteinkoplet reseptor

Country Status (10)

Country Link
EP (1) EP1820026A1 (no)
JP (1) JP2008521419A (no)
KR (1) KR20070086003A (no)
CN (1) CN101107529A (no)
AU (1) AU2005311321A1 (no)
CA (1) CA2587534A1 (no)
NO (1) NO20073294L (no)
RU (1) RU2007124609A (no)
WO (1) WO2006058889A1 (no)
ZA (1) ZA200704526B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005103283A1 (ja) * 2004-04-23 2005-11-03 Takeda Pharmaceutical Company Limited 新規スクリーニング方法
CA2652398A1 (en) * 2006-06-08 2007-12-13 Janssen Pharmaceutica N.V. G protein-coupled receptor 39 (gpr39)
CN111443209B (zh) * 2020-03-26 2022-12-20 中国中医科学院医学实验中心 一种筛选非激动剂型PPARγ配体的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001081634A2 (en) * 2000-04-26 2001-11-01 Millennium Pharmaceuticals, Inc. Methods and compositions for the diagnosis and treatment of cardiovascular and tumorigenic disease using 4941
US20020192711A1 (en) * 2001-04-20 2002-12-19 Nestor John J. Methods for identifying ligands of G-Protein-Coupled receptors
US20030232769A1 (en) * 2002-06-17 2003-12-18 Isis Pharmaceuticals Inc. Antisense modulation of G protein-coupled receptor 39 expression
WO2004040000A2 (en) * 2002-09-09 2004-05-13 Nura, Inc G protein coupled receptors and uses thereof
US20040071708A1 (en) * 2002-09-26 2004-04-15 Immusol, Inc. GPR 39 modulators that control cancerous cell growth
CN1708589A (zh) * 2002-10-31 2005-12-14 詹森药业有限公司 Cns中crh应答基因
WO2004099782A2 (en) * 2003-05-05 2004-11-18 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g-protein-coupled receptor gpr39 (gpr39)

Also Published As

Publication number Publication date
EP1820026A1 (en) 2007-08-22
WO2006058889A1 (en) 2006-06-08
CN101107529A (zh) 2008-01-16
RU2007124609A (ru) 2009-01-10
CA2587534A1 (en) 2006-06-08
JP2008521419A (ja) 2008-06-26
KR20070086003A (ko) 2007-08-27
ZA200704526B (en) 2008-11-26
AU2005311321A1 (en) 2006-06-08

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application