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NO20073019L - Pyrasolonforbindelser som metabotrope glutamatreseptor-antagonister for behandlingen av nevrotiske og psykiatriske lidelser - Google Patents

Pyrasolonforbindelser som metabotrope glutamatreseptor-antagonister for behandlingen av nevrotiske og psykiatriske lidelser

Info

Publication number
NO20073019L
NO20073019L NO20073019A NO20073019A NO20073019L NO 20073019 L NO20073019 L NO 20073019L NO 20073019 A NO20073019 A NO 20073019A NO 20073019 A NO20073019 A NO 20073019A NO 20073019 L NO20073019 L NO 20073019L
Authority
NO
Norway
Prior art keywords
compounds
treatment
pyrasolone
neurotic
psychiatric disorders
Prior art date
Application number
NO20073019A
Other languages
English (en)
Inventor
Michael Balestra
Rebecca Ann Urbanek
Methvin Isaac
Abdelmalik Slassi
Radhakrishnan Ukkiramapandian
Fupeng Ma
Ian Egle
Gary Steelman
Sally Walsh
Heather Bunting
Deborah Chen
Janet Forst
Jennifer Frey
David Nugiel
Guang-Ri Sun
Babu Sundar
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20073019L publication Critical patent/NO20073019L/no

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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • A—HUMAN NECESSITIES
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    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
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    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C07D231/20—One oxygen atom attached in position 3 or 5
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Forbindelser med formel (I), hvor R1, R2, R3, R4, R5, R6, X og n er som definert for formel (I) i beskrivelsen, fremgangsmåter for fremstillingen av forbindelser og nye mellomprodukter som brukes ved fremstillingen, farmasøytiske sammensetninger som inneholder forbindelsene og anvendelsene av forbindelsene ved behandling eller forebygging av nevrologiske og psykiatriske lidelser som er assosiert med glutamatdysfunksjon.
NO20073019A 2004-12-27 2007-06-13 Pyrasolonforbindelser som metabotrope glutamatreseptor-antagonister for behandlingen av nevrotiske og psykiatriske lidelser NO20073019L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63836904P 2004-12-27 2004-12-27
PCT/US2005/046606 WO2006071730A1 (en) 2004-12-27 2005-12-22 Pyrazolone compounds as metabotropic glutamate receptor agonists for the treatment of neurological and psychiatric disorders

Publications (1)

Publication Number Publication Date
NO20073019L true NO20073019L (no) 2007-09-27

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NO20073019A NO20073019L (no) 2004-12-27 2007-06-13 Pyrasolonforbindelser som metabotrope glutamatreseptor-antagonister for behandlingen av nevrotiske og psykiatriske lidelser

Country Status (12)

Country Link
US (1) US20090069340A1 (no)
EP (1) EP1833800A1 (no)
JP (1) JP2008525478A (no)
KR (1) KR20070106690A (no)
CN (1) CN101128435A (no)
AU (1) AU2005322173A1 (no)
BR (1) BRPI0517423A (no)
CA (1) CA2591003A1 (no)
IL (1) IL183880A0 (no)
MX (1) MX2007007220A (no)
NO (1) NO20073019L (no)
WO (1) WO2006071730A1 (no)

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