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NO2006008I1 - Natalizumab, anti alfa-4 integrin humanized monoclonal antibody - Google Patents

Natalizumab, anti alfa-4 integrin humanized monoclonal antibody

Info

Publication number
NO2006008I1
NO2006008I1 NO2006008C NO2006008C NO2006008I1 NO 2006008 I1 NO2006008 I1 NO 2006008I1 NO 2006008 C NO2006008 C NO 2006008C NO 2006008 C NO2006008 C NO 2006008C NO 2006008 I1 NO2006008 I1 NO 2006008I1
Authority
NO
Norway
Prior art keywords
natalizumab
monoclonal antibody
humanized monoclonal
anti alpha
integrin humanized
Prior art date
Application number
NO2006008C
Other languages
English (en)
Other versions
NO2006008I2 (no
Original Assignee
Elan Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Pharm Inc filed Critical Elan Pharm Inc
Publication of NO2006008I1 publication Critical patent/NO2006008I1/no
Publication of NO2006008I2 publication Critical patent/NO2006008I2/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2842—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO2006008C 1994-01-25 2006-08-07 Natalizumab, anti alfa-4 integrin humanized monoclonal antibody NO2006008I2 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18626994A 1994-01-25 1994-01-25
PCT/US1995/001219 WO1995019790A1 (en) 1994-01-25 1995-01-25 Humanized antibodies against leukocyte adhesion molecule vla-4

Publications (2)

Publication Number Publication Date
NO2006008I1 true NO2006008I1 (no) 2006-08-07
NO2006008I2 NO2006008I2 (no) 2009-06-15

Family

ID=22684288

Family Applications (3)

Application Number Title Priority Date Filing Date
NO19963097A NO319867B1 (no) 1994-01-25 1996-07-24 Humaniserte antistoffer mot leukocytt-adhesjonsmolekyl VLA-4, bindingsfragment derav, farmasoytisk preparat omfattende det humaniserte antistoffet eller et bindingsfragment derav, samt anvendelser av det humaniserte antistoff.
NO2006008C NO2006008I2 (no) 1994-01-25 2006-08-07 Natalizumab, anti alfa-4 integrin humanized monoclonal antibody
NO2017040C NO2017040I2 (no) 1994-01-25 2017-08-01 Natalizumab, anti alfa-4 integrin humanisert monoklonalt antistoff - forlenget SPC

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO19963097A NO319867B1 (no) 1994-01-25 1996-07-24 Humaniserte antistoffer mot leukocytt-adhesjonsmolekyl VLA-4, bindingsfragment derav, farmasoytisk preparat omfattende det humaniserte antistoffet eller et bindingsfragment derav, samt anvendelser av det humaniserte antistoff.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO2017040C NO2017040I2 (no) 1994-01-25 2017-08-01 Natalizumab, anti alfa-4 integrin humanisert monoklonalt antistoff - forlenget SPC

Country Status (21)

Country Link
EP (2) EP0804237B8 (no)
JP (5) JP4115517B2 (no)
KR (1) KR100367948B1 (no)
CN (1) CN1211123C (no)
AT (1) ATE333895T1 (no)
AU (1) AU703152B2 (no)
CA (1) CA2182013C (no)
DE (2) DE69535133T2 (no)
DK (2) DK1759709T3 (no)
ES (2) ES2424292T3 (no)
FI (1) FI117509B (no)
FR (1) FR06C0024I2 (no)
HU (1) HU220799B1 (no)
LU (1) LU91271I2 (no)
MX (1) MX9602971A (no)
NL (1) NL300238I2 (no)
NO (3) NO319867B1 (no)
NZ (1) NZ279730A (no)
PL (1) PL181827B1 (no)
PT (1) PT804237E (no)
WO (1) WO1995019790A1 (no)

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US7435802B2 (en) 1994-01-25 2008-10-14 Elan Pharaceuticals, Inc. Humanized anti-VLA4 immunoglobulins
US6551593B1 (en) 1995-02-10 2003-04-22 Millennium Pharmaceuticals, Inc. Treatment of Inflammatory bowel disease by inhibiting binding and/or signalling through α 4 β 7 and its ligands and madcam
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US7147851B1 (en) * 1996-08-15 2006-12-12 Millennium Pharmaceuticals, Inc. Humanized immunoglobulin reactive with α4β7 integrin
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DE19821483A1 (de) 1998-05-14 1999-11-18 Hoechst Marion Roussel De Gmbh Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
US7618630B2 (en) 1998-09-14 2009-11-17 Board Of Regents, The University Of Texas System Methods of treating multiple myeloma and myeloma-induced bone resorption using integrin antagonists
DK1113810T3 (da) * 1998-09-14 2009-04-06 Univ Texas Fremgangsmåder til behandling af multipelt myelom og myelom-induceret knogleresorption under anvendelse af antagonister af integrin/receptor-binding
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US6949245B1 (en) 1999-06-25 2005-09-27 Genentech, Inc. Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
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DE10111877A1 (de) 2001-03-10 2002-09-12 Aventis Pharma Gmbh Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
EE200300509A (et) 2001-04-13 2004-08-16 Biogen, Inc. Antikehad VLA-1 vastu
DE10137595A1 (de) 2001-08-01 2003-02-13 Aventis Pharma Gmbh Neue Imidazolidinderivate, ihre Herstellung und ihre Verwendung
PT2336184E (pt) * 2002-02-25 2015-03-09 Biogen Idec Inc Administração de agentes para o tratamento da inflamação
EP1499352A4 (en) * 2002-04-12 2006-10-11 Medimmune Inc ANTI-INTERLEUKIN-9 RECOMBINANT ANTIBODIES
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ATE471946T1 (de) * 2002-12-17 2010-07-15 Merck Patent Gmbh Humanisierter antikörper (h14.18) des maus antikörpers 14.18, der gd2 bindet und seine fusion mit il-2
CU23403A1 (es) * 2003-04-23 2009-08-04 Centro Inmunologia Molecular Anticuerpos recombinantes y fragmentos que reconocen el gangliósido n-glicolil gm3 y su uso para diagnóstico y tratamiento de tumores
RU2390520C2 (ru) 2003-12-22 2010-05-27 Адзиномото Ко., Инк. Новые производные фенилаланина
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Also Published As

Publication number Publication date
FI962958A0 (fi) 1996-07-24
PT804237E (pt) 2006-10-31
PL181827B1 (pl) 2001-09-28
ATE333895T1 (de) 2006-08-15
NO2017040I1 (no) 2017-08-01
DK0804237T3 (da) 2006-10-16
NO2006008I2 (no) 2009-06-15
MX9602971A (es) 1998-01-31
JP5487382B2 (ja) 2014-05-07
EP1759709A1 (en) 2007-03-07
CA2182013A1 (en) 1995-07-27
CN1140413A (zh) 1997-01-15
EP1759709B1 (en) 2013-02-27
JPH09508272A (ja) 1997-08-26
KR970700513A (ko) 1997-02-12
JP2013165718A (ja) 2013-08-29
FI117509B (fi) 2006-11-15
JP2006045237A (ja) 2006-02-16
JP4115517B2 (ja) 2008-07-09
FI962958L (fi) 1996-09-24
KR100367948B1 (ko) 2003-07-12
NO319867B1 (no) 2005-09-26
JP2009235078A (ja) 2009-10-15
CA2182013C (en) 2007-07-17
AU1696095A (en) 1995-08-08
HUT75129A (en) 1997-04-28
DE122006000043I1 (de) 2007-02-15
LU91271I2 (fr) 2006-10-02
NO963097D0 (no) 1996-07-24
EP0804237A1 (en) 1997-11-05
AU703152B2 (en) 1999-03-18
HU9602019D0 (en) 1996-09-30
NO2017040I2 (no) 2018-08-28
DE69535133D1 (de) 2006-09-07
NO963097L (no) 1996-09-24
EP0804237B1 (en) 2006-07-26
NZ279730A (en) 1998-04-27
PL315634A1 (en) 1996-11-25
ES2270425T3 (es) 2007-04-01
FR06C0024I1 (no) 2006-10-13
HU220799B1 (hu) 2002-05-28
WO1995019790A1 (en) 1995-07-27
FR06C0024I2 (fr) 2009-01-02
NL300238I1 (no) 2006-10-02
ES2424292T3 (es) 2013-09-30
EP0804237B8 (en) 2006-11-08
DK1759709T3 (da) 2013-06-10
EP0804237A4 (en) 2003-04-16
JP2013173738A (ja) 2013-09-05
NL300238I2 (nl) 2007-05-01
CN1211123C (zh) 2005-07-20
DE69535133T2 (de) 2008-08-21

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CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: BIOGEN MA INC., US