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NO20055692D0 - Intravenous injection of non-neurotoxic plasminogen activators for the treatment of cerebral stroke - Google Patents

Intravenous injection of non-neurotoxic plasminogen activators for the treatment of cerebral stroke

Info

Publication number
NO20055692D0
NO20055692D0 NO20055692A NO20055692A NO20055692D0 NO 20055692 D0 NO20055692 D0 NO 20055692D0 NO 20055692 A NO20055692 A NO 20055692A NO 20055692 A NO20055692 A NO 20055692A NO 20055692 D0 NO20055692 D0 NO 20055692D0
Authority
NO
Norway
Prior art keywords
treatment
intravenous injection
plasminogen activators
cerebral stroke
neurotoxic plasminogen
Prior art date
Application number
NO20055692A
Other languages
Norwegian (no)
Other versions
NO20055692L (en
NO337485B1 (en
Inventor
Wolf-Dieter Schleuning
Mariola Sohngen
Wolfgang Sohngen
Robert Medcalf
Original Assignee
Paion Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2003/004729 external-priority patent/WO2004096267A1/en
Application filed by Paion Deutschland Gmbh filed Critical Paion Deutschland Gmbh
Publication of NO20055692D0 publication Critical patent/NO20055692D0/en
Publication of NO20055692L publication Critical patent/NO20055692L/en
Publication of NO337485B1 publication Critical patent/NO337485B1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49Urokinase; Tissue plasminogen activator
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/57Protease inhibitors from animals; from humans
    • A61K38/58Protease inhibitors from animals; from humans from leeches, e.g. hirudin, eglin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Hospice & Palliative Care (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20055692A 2003-05-02 2005-12-01 Use of a non-neurotoxic plasminogen activator from Desmodus rotundus DSPA-alpha-1, for the preparation of a therapeutic drug for intravenous use in the treatment of cerebral stroke NO337485B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EPPCT/EP2003/004608 2003-05-02
PCT/EP2003/004729 WO2004096267A1 (en) 2003-05-02 2003-05-06 Intravenous injection of non-neurotoxic plasminogen activators for the treatment of stroke
PCT/EP2004/004626 WO2004096268A2 (en) 2003-05-02 2004-04-30 Intravenous injection of plasminogen non-neurotoxic activators for treating cerebral stroke

Publications (3)

Publication Number Publication Date
NO20055692D0 true NO20055692D0 (en) 2005-12-01
NO20055692L NO20055692L (en) 2006-01-30
NO337485B1 NO337485B1 (en) 2016-04-25

Family

ID=35610451

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20055692A NO337485B1 (en) 2003-05-02 2005-12-01 Use of a non-neurotoxic plasminogen activator from Desmodus rotundus DSPA-alpha-1, for the preparation of a therapeutic drug for intravenous use in the treatment of cerebral stroke

Country Status (10)

Country Link
EP (1) EP1622639B1 (en)
JP (1) JP2006525270A (en)
KR (1) KR101212631B1 (en)
BR (1) BRPI0409865A (en)
CA (1) CA2524573A1 (en)
HR (1) HRP20050903B1 (en)
NO (1) NO337485B1 (en)
NZ (1) NZ543367A (en)
PL (1) PL1622639T3 (en)
WO (1) WO2004096268A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10153601A1 (en) 2001-11-02 2003-05-22 Paion Gmbh DSPA for the treatment of stroke
US7759506B2 (en) 2002-02-25 2010-07-20 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
DE10342518A1 (en) * 2003-09-12 2005-05-12 Paion Gmbh Plasminogen activators with reduced lysine binding capacity
US8030350B2 (en) 2005-02-24 2011-10-04 Diffusion Pharmaceuticals Llc Trans carotenoids, their synthesis, formulation and uses
WO2008022801A1 (en) * 2006-08-25 2008-02-28 Paion Deutschland Gmbh Method for the manufacture of a medicament for treating hemorrhagic stroke
EP1897554A1 (en) * 2006-08-25 2008-03-12 PAION Deutschland GmbH Method for the manufacture of a medicament for treating hemorrhagic stroke
CA2683760C (en) 2007-04-13 2015-05-19 Diffusion Pharmaceuticals Llc Use of bipolar trans carotenoids as a pretreatment and in the treatment of peripheral vascular disease
HUE053131T2 (en) 2009-06-10 2021-06-28 Nono Inc Treatment regimes for treatment of neurological disease
JP5787884B2 (en) 2009-06-22 2015-09-30 ディフュージョン・ファーマシューティカルズ・エルエルシー Diffusion enhancing compounds and their use alone or in combination with thrombolytic agents
JP5823672B2 (en) * 2009-07-27 2015-11-25 国立大学法人 新潟大学 Pharmaceutical composition for treating cerebral infarction comprising receptor signaling inhibitor
US8652476B2 (en) 2009-07-27 2014-02-18 Niigata University Pharmaceutical composition for treating ischemic events
JP5823671B2 (en) * 2009-07-27 2015-11-25 国立大学法人 新潟大学 Pharmaceutical composition for the treatment of cerebral infarction comprising immunological preparation
ES2654945T3 (en) 2010-06-02 2018-02-15 Diffusion Pharmaceuticals Llc Oral formulations of trans bipolar carotenoids
DK3427748T3 (en) 2011-06-24 2022-04-19 Nono Inc COMBINATION THERAPY AGAINST ICE CREAM
US9241970B2 (en) 2011-12-13 2016-01-26 Nono Inc. Therapy for subarachnoid hemorrhage and ischemia
CN109152839A (en) 2016-03-24 2019-01-04 扩散药品有限公司 Purposes of the bipolarity trans-carotenoid together with chemotherapy and radiotherapy in treating cancer
US10617756B2 (en) 2017-01-05 2020-04-14 Shimojani, LLC Drug regimen for treatment of cerebral ischemia

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI100403B (en) * 1988-07-20 1997-11-28 Schering Ag Process for Preparation of Glycocylated or Glycocylated Pla Sminogen Activators of Vampire Bats Saliva
NL8902454A (en) * 1989-10-03 1991-05-01 Stichting Centraal Lab MUTANTS OF THE HUMANE PLASMINOGENIC ACTIVATOR INHIBITOR 1 (PAI-1), THEIR PREPARATION AND USE, AND RECOMBINANT POLYNUCLEOTIDES INCLUDING GENETIC INFORMATION CODING FOR THESE MUTANTS.
DE10153601A1 (en) * 2001-11-02 2003-05-22 Paion Gmbh DSPA for the treatment of stroke

Also Published As

Publication number Publication date
WO2004096268A3 (en) 2005-04-21
NZ543367A (en) 2010-06-25
WO2004096268A2 (en) 2004-11-11
KR101212631B1 (en) 2012-12-14
NO20055692L (en) 2006-01-30
HRP20050903B1 (en) 2013-11-22
EP1622639B1 (en) 2013-01-16
JP2006525270A (en) 2006-11-09
NO337485B1 (en) 2016-04-25
KR20060020616A (en) 2006-03-06
CA2524573A1 (en) 2004-11-11
HRP20050903A2 (en) 2006-08-31
PL1622639T3 (en) 2013-06-28
EP1622639A2 (en) 2006-02-08
BRPI0409865A (en) 2006-05-16

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