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NO20051404L - Pyridylsubstituerte heterocykluser som er nyttige for behandling eller forebyggelse av HCV infeksjon - Google Patents

Pyridylsubstituerte heterocykluser som er nyttige for behandling eller forebyggelse av HCV infeksjon

Info

Publication number
NO20051404L
NO20051404L NO20051404A NO20051404A NO20051404L NO 20051404 L NO20051404 L NO 20051404L NO 20051404 A NO20051404 A NO 20051404A NO 20051404 A NO20051404 A NO 20051404A NO 20051404 L NO20051404 L NO 20051404L
Authority
NO
Norway
Prior art keywords
pyridyl
treating
hcv infection
substituted heterocycles
preventing hcv
Prior art date
Application number
NO20051404A
Other languages
English (en)
Inventor
Rajinder Singh
Dane Goff
John Partridge
Original Assignee
Rigel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rigel Pharmaceuticals Inc filed Critical Rigel Pharmaceuticals Inc
Publication of NO20051404L publication Critical patent/NO20051404L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Det er beskrevet pyridylsubstituerte heterocykluser og hydroisomerer derav og farmasøytiske preparater derav som inhiberer replikasjon og/eller proliferasjon av HCV-virus. Det er også beskrevet anvendelse av pyridylheterocyklusene og hydroisomerene derav og/eller farmasøytiske preparater omfattende forbindelsene for å behandle eller forebygge HCV-infeksjon.
NO20051404A 2002-08-23 2005-03-17 Pyridylsubstituerte heterocykluser som er nyttige for behandling eller forebyggelse av HCV infeksjon NO20051404L (no)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US40546702P 2002-08-23 2002-08-23
US41783702P 2002-10-11 2002-10-11
US47137303P 2003-05-15 2003-05-15
US10/646,348 US7157473B2 (en) 2002-08-23 2003-08-22 Pyridyl substituted heterocycles useful for treating or preventing HCV infection
PCT/US2003/026478 WO2004018463A2 (en) 2002-08-23 2003-08-22 Pyridyl substituted heterocycles useful for treating or preventing hcv infection

Publications (1)

Publication Number Publication Date
NO20051404L true NO20051404L (no) 2005-05-10

Family

ID=31950772

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20051404A NO20051404L (no) 2002-08-23 2005-03-17 Pyridylsubstituerte heterocykluser som er nyttige for behandling eller forebyggelse av HCV infeksjon

Country Status (15)

Country Link
US (3) US7157473B2 (no)
EP (1) EP1530569A2 (no)
JP (1) JP2006501312A (no)
KR (1) KR20050033653A (no)
AU (1) AU2003262831A1 (no)
BR (1) BR0313755A (no)
CA (1) CA2494164A1 (no)
HR (1) HRP20050168A2 (no)
IL (1) IL166639A0 (no)
MX (1) MXPA05002082A (no)
NO (1) NO20051404L (no)
NZ (1) NZ537980A (no)
PL (1) PL374536A1 (no)
RS (1) RS20050175A (no)
WO (1) WO2004018463A2 (no)

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MY151199A (en) 2001-11-02 2014-04-30 Rigel Pharmaceuticals Inc Substituted diphenyl heterocycles useful for treating hcv infection
WO2004018463A2 (en) * 2002-08-23 2004-03-04 Rigel Pharmaceuticals, Inc. Pyridyl substituted heterocycles useful for treating or preventing hcv infection
EP1620412A2 (en) * 2003-05-02 2006-02-01 Rigel Pharmaceuticals, Inc. Heterocyclic compounds and hydro isomers thereof
US7115642B2 (en) 2003-05-02 2006-10-03 Rigel Pharmaceuticals, Inc. Substituted diphenyl isoxazoles, pyrazoles and oxadiazoles useful for treating HCV infection
US7220745B2 (en) 2003-05-15 2007-05-22 Rigel Pharmaceuticals Heterocyclic compounds useful to treat HCV
JP2007501185A (ja) 2003-07-25 2007-01-25 イデニクス（ケイマン）リミテツド Ｃ型肝炎を含むフラビウイルス関連疾患を治療するためのプリンヌクレオシド類似体
WO2005049065A2 (en) * 2003-11-19 2005-06-02 Rigel Pharmaceuticals, Inc. Synergistic combinations of dihaloacetamide with interferon or ribavirin for treatment hcv infections
WO2005063225A1 (en) * 2003-12-19 2005-07-14 Rigel Pharmaceuticals, Inc. Compositions and methods for treating hepatitis c virus (hcv) infection
US7514434B2 (en) 2004-02-23 2009-04-07 Rigel Pharmaceuticals, Inc. Heterocyclic compounds having an oxadiazole moiety and hydro isomers thereof
US20050239751A1 (en) * 2004-03-26 2005-10-27 Rigel Pharmaceuticals, Inc. Heterocyclic anti-viral compounds comprising metabolizable moieties and their uses
CA2606106A1 (en) * 2005-05-02 2007-03-08 Rigel Pharmaceuticals, Inc. Heterocyclic anti-viral compounds comprising metabolizable moieties and their uses
EP1924205B1 (en) * 2005-08-10 2012-12-19 C.R.Bard, Inc. Single-insertion, multiple sample biopsy device
KR100890862B1 (ko) * 2005-11-07 2009-03-27 주식회사 엘지화학 유기 발광 소자 및 이의 제조 방법
CN101969949B (zh) * 2008-03-14 2013-12-25 大塚制药株式会社 Mmp-2及/或mmp-9抑制剂
US8362020B2 (en) * 2009-12-30 2013-01-29 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
EP3315492B1 (en) 2015-06-23 2020-09-16 Kissei Pharmaceutical Co., Ltd. Pyrazole derivative, or pharmaceutically acceptable salt thereof
CN116535399B (zh) * 2022-01-25 2024-02-27 中国药科大学 3-羟基-5-(异噁唑-5-基)吡啶甲酰甘氨酸类化合物、制法、药物组合物和应用
WO2025037036A1 (en) * 2023-08-17 2025-02-20 Sanofi Pyridyl imidazoles, their preparation and their therapeutic application

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Also Published As

Publication number Publication date
BR0313755A (pt) 2005-06-21
PL374536A1 (en) 2005-10-31
JP2006501312A (ja) 2006-01-12
WO2004018463A3 (en) 2004-05-06
IL166639A0 (en) 2006-01-15
CA2494164A1 (en) 2004-03-04
US7332602B2 (en) 2008-02-19
US20040127497A1 (en) 2004-07-01
KR20050033653A (ko) 2005-04-12
WO2004018463A2 (en) 2004-03-04
US20080171871A1 (en) 2008-07-17
MXPA05002082A (es) 2005-06-08
HRP20050168A2 (en) 2005-10-31
US20070155966A1 (en) 2007-07-05
NZ537980A (en) 2007-08-31
US7157473B2 (en) 2007-01-02
US7714137B2 (en) 2010-05-11
RS20050175A (en) 2007-09-21
AU2003262831A1 (en) 2004-03-11
EP1530569A2 (en) 2005-05-18

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