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NO20023276L - Fremgangsmåter fremstilling av betulinsyre - Google Patents

Fremgangsmåter fremstilling av betulinsyre

Info

Publication number
NO20023276L
NO20023276L NO20023276A NO20023276A NO20023276L NO 20023276 L NO20023276 L NO 20023276L NO 20023276 A NO20023276 A NO 20023276A NO 20023276 A NO20023276 A NO 20023276A NO 20023276 L NO20023276 L NO 20023276L
Authority
NO
Norway
Prior art keywords
betulin
acetate
betulinic acid
dibenzoate
betulinic
Prior art date
Application number
NO20023276A
Other languages
English (en)
Other versions
NO20023276D0 (no
Inventor
Pavel A Krasutsky
Robert M Carlson
Vitaliy V Nesterenko
Original Assignee
Univ Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minnesota filed Critical Univ Minnesota
Publication of NO20023276D0 publication Critical patent/NO20023276D0/no
Publication of NO20023276L publication Critical patent/NO20023276L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/30—Unsaturated compounds
    • C07C62/32—Unsaturated compounds containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/14—Preparation of carboxylic acid esters from carboxylic acid halides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/28—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/29—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group by introduction of oxygen-containing functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/52—Ortho- or ortho- and peri-condensed systems containing five condensed rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
NO20023276A 2000-01-11 2002-07-05 Fremgangsmåter fremstilling av betulinsyre NO20023276L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/480,406 US6232481B1 (en) 2000-01-11 2000-01-11 Method for manufacturing betulinic acid
PCT/US2001/000991 WO2001051451A2 (en) 2000-01-11 2001-01-11 Methods for manufacturing betulinic acid

Publications (2)

Publication Number Publication Date
NO20023276D0 NO20023276D0 (no) 2002-07-05
NO20023276L true NO20023276L (no) 2002-09-09

Family

ID=23907841

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20023276A NO20023276L (no) 2000-01-11 2002-07-05 Fremgangsmåter fremstilling av betulinsyre

Country Status (10)

Country Link
US (4) US6232481B1 (no)
EP (1) EP1248766B1 (no)
JP (1) JP2003519674A (no)
AT (1) ATE328862T1 (no)
AU (1) AU5789601A (no)
CA (1) CA2396574A1 (no)
DE (1) DE60120352T2 (no)
ES (1) ES2264694T3 (no)
NO (1) NO20023276L (no)
WO (1) WO2001051451A2 (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6232481B1 (en) * 2000-01-11 2001-05-15 Regents Of The University Of Minnesota Method for manufacturing betulinic acid
US7407480B2 (en) * 2001-07-27 2008-08-05 Ams Research Corporation Method and apparatus for correction of urinary and gynecological pathologies, including treatment of incontinence cystocele
US20080308426A1 (en) * 2005-03-29 2008-12-18 Krasutsky Pavel A Electrochemical Method for the Production of Betulin Aldehyde
EP1869063A2 (en) * 2005-03-29 2007-12-26 Regents Of The University Of Minnesota Methods of manufacturing bioactive 3-esters of betulinic aldehyde and betulinic acid
US20090076290A1 (en) * 2005-03-29 2009-03-19 Regents Of The University Of Minnesota Selective oxidation of triterpenes employing tempo
WO2006133314A2 (en) * 2005-06-08 2006-12-14 Regents Of The University Of Minnesota Synthesis of betulonic and betulinic aldehydes
WO2007121482A1 (en) * 2006-04-18 2007-10-25 Regents Of The University Of Minnesota Depolymerization extraction of compounds from birch bark
KR100941595B1 (ko) * 2008-06-05 2010-02-11 주식회사 알앤엘바이오 바이러스 억제제로서 유용한 트리테르페노이드계 화합물
CN101302244B (zh) * 2008-06-06 2011-04-13 东北林业大学 一种桦木酸的生产方法
CN102399255B (zh) * 2010-09-09 2015-04-15 东北林业大学 一种桦木酸的制备方法
RU2560710C1 (ru) * 2014-10-30 2015-08-20 Федеральное Государственное Бюджетное Учреждение Науки Институт Химии И Химической Технологии Сибирского Отделения Российской Академии Наук (Иххт Со Ран) Способ получения производных 3-ацетата-28-сульфата бетулина
PL227790B1 (pl) 2015-08-13 2018-01-31 Slaski Univ Medyczny W Katowicach Fosfoniany acetylenowych pochodnych betuliny o działaniu przeciwnowotworowym, sposób ich wytwarzania i zastosowanie.
CN110577470B (zh) * 2019-10-09 2022-12-27 蚌埠学院 一种利用沸石分子筛催化2-萘甲醚选择性硝化的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW212790B (no) 1991-10-15 1993-09-11 Ciba Geigy Ag
US5804575A (en) 1997-03-27 1998-09-08 The Board Of Trustees Of The University Of Illinois Methods of manufacturing betulinic acid
DK1068219T3 (da) * 1998-03-02 2007-04-30 Univ North Carolina Acylerede betulin- og dihydrobetulinderivater samt fremstilling og anvendelse deraf
US6232481B1 (en) 2000-01-11 2001-05-15 Regents Of The University Of Minnesota Method for manufacturing betulinic acid

Also Published As

Publication number Publication date
JP2003519674A (ja) 2003-06-24
US20010007908A1 (en) 2001-07-12
ES2264694T3 (es) 2007-01-16
US20020028960A1 (en) 2002-03-07
US6271405B2 (en) 2001-08-07
US20020016482A1 (en) 2002-02-07
ATE328862T1 (de) 2006-06-15
WO2001051451A3 (en) 2002-03-07
NO20023276D0 (no) 2002-07-05
US6407270B1 (en) 2002-06-18
EP1248766B1 (en) 2006-06-07
EP1248766A2 (en) 2002-10-16
US6232481B1 (en) 2001-05-15
DE60120352T2 (de) 2007-04-26
CA2396574A1 (en) 2001-07-19
AU5789601A (en) 2001-07-24
WO2001051451A2 (en) 2001-07-19
DE60120352D1 (de) 2006-07-20
US6867314B2 (en) 2005-03-15

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