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NO20022728D0 - Nye aminopropylfosfinsyrer - Google Patents

Nye aminopropylfosfinsyrer

Info

Publication number
NO20022728D0
NO20022728D0 NO20022728A NO20022728A NO20022728D0 NO 20022728 D0 NO20022728 D0 NO 20022728D0 NO 20022728 A NO20022728 A NO 20022728A NO 20022728 A NO20022728 A NO 20022728A NO 20022728 D0 NO20022728 D0 NO 20022728D0
Authority
NO
Norway
Prior art keywords
novel
aminopropylphosphinic acids
aminopropylphosphinic
acids
novel aminopropylphosphinic
Prior art date
Application number
NO20022728A
Other languages
English (en)
Other versions
NO20022728L (no
NO329595B1 (no
Inventor
Thomas Elebring
Peter Guzzo
Anders Holmen
Thomas Olsson
Marianne Swansson
Sverker Von Unge
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0003640A external-priority patent/SE0003640D0/xx
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20022728D0 publication Critical patent/NO20022728D0/no
Publication of NO20022728L publication Critical patent/NO20022728L/no
Publication of NO329595B1 publication Critical patent/NO329595B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/48Phosphonous acids [RP(OH)2] including [RHP(=O)(OH)]; Thiophosphonous acids including [RP(SH)2], [RHP(=S)(SH)]; Derivatives thereof
    • C07F9/4808Phosphonous acids [RP(OH)2] including [RHP(=O)(OH)]; Thiophosphonous acids including [RP(SH)2], [RHP(=S)(SH)]; Derivatives thereof the acid moiety containing a substituent or structure which is considered as characteristic
    • C07F9/4816Acyclic saturated acids or derivatices which can have further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/30Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Addiction (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO20022728A 1999-12-09 2002-06-07 Nye aminopropylfosfinsyrer, farmasoytiske formuleringer inneholdende slike, samt mellomprodukter til fremstilling av slike NO329595B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9904508A SE9904508D0 (sv) 1999-12-09 1999-12-09 New compounds
SE0003640A SE0003640D0 (sv) 2000-10-09 2000-10-09 New compounds
PCT/SE2000/002426 WO2001042252A1 (en) 1999-12-09 2000-12-04 New aminopropylphosphinic acids

Publications (3)

Publication Number Publication Date
NO20022728D0 true NO20022728D0 (no) 2002-06-07
NO20022728L NO20022728L (no) 2002-08-07
NO329595B1 NO329595B1 (no) 2010-11-22

Family

ID=26655259

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20022728A NO329595B1 (no) 1999-12-09 2002-06-07 Nye aminopropylfosfinsyrer, farmasoytiske formuleringer inneholdende slike, samt mellomprodukter til fremstilling av slike

Country Status (33)

Country Link
US (5) US6576626B2 (no)
EP (2) EP1484333A1 (no)
JP (2) JP3914435B2 (no)
KR (1) KR100689144B1 (no)
CN (1) CN1198832C (no)
AR (1) AR030541A1 (no)
AT (1) ATE282043T1 (no)
AU (1) AU780459B2 (no)
BR (1) BR0016253A (no)
CA (1) CA2397583C (no)
CZ (1) CZ20021983A3 (no)
DE (1) DE60015796T2 (no)
DK (1) DK1240172T3 (no)
EE (1) EE05067B1 (no)
ES (1) ES2230174T3 (no)
HK (2) HK1048321B (no)
HU (1) HUP0300301A3 (no)
IL (2) IL149840A0 (no)
IS (1) IS2231B (no)
MX (1) MXPA02005536A (no)
MY (1) MY125414A (no)
NO (1) NO329595B1 (no)
NZ (1) NZ519376A (no)
PL (1) PL201789B1 (no)
PT (1) PT1240172E (no)
RU (1) RU2260595C2 (no)
SE (1) SE9904508D0 (no)
SI (1) SI1240172T1 (no)
SK (1) SK286904B6 (no)
TW (1) TWI228510B (no)
UA (1) UA71649C2 (no)
WO (1) WO2001042252A1 (no)
ZA (1) ZA200204127B (no)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
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SE9904508D0 (sv) * 1999-12-09 1999-12-09 Astra Ab New compounds
US7319095B2 (en) * 1999-12-09 2008-01-15 Astrazeneca Ab Use of GABAB receptor agonists
CN1491106A (zh) * 2001-02-05 2004-04-21 �޲��ء��߶�ķ˹�� 食管活动性功能紊乱和胃-食管反流性疾病的治疗方法
AR033779A1 (es) * 2001-06-08 2004-01-07 Astrazeneca Ab Compuestos utiles en la enfermedad de reflujo
SE0201940D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination II
SE0201939D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination
SE0401653D0 (sv) 2004-06-24 2004-06-24 Astrazeneca Ab New compounds
SE0402462D0 (sv) * 2004-10-08 2004-10-08 Astrazeneca Ab New process
WO2006050471A2 (en) 2004-11-03 2006-05-11 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
US7494985B2 (en) 2004-11-03 2009-02-24 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use
US20060160777A1 (en) * 2004-12-27 2006-07-20 Anders Lehmann New use of GABAbeta receptor agonists
US7745474B2 (en) 2005-12-23 2010-06-29 Astrazeneca Ab Imidazole derivatives for the treatment of gastrointestinal disorders
JP2009521430A (ja) 2005-12-23 2009-06-04 アストラゼネカ・アクチエボラーグ Gaba−b受容体モジュレーター
US7585996B2 (en) 2006-09-15 2009-09-08 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
ATE528310T1 (de) 2007-05-04 2011-10-15 Astrazeneca Ab Verfahren zur synthese von alkylphosphinsäuren durch initiierung eines amins und eines aminoxids
EP2217245A4 (en) * 2007-07-25 2011-01-12 Astrazeneca Ab USE OF (3-AMINO-2-FLUOROPROPYL) -PHOSPHIC ACID FOR THE TREATMENT OF NERD
WO2009082348A1 (en) * 2007-12-21 2009-07-02 Astrazeneca Ab Novel crystalline form c of (2r)-(3-amino-2-fluoropropyl)phosphinic acid
PE20091310A1 (es) * 2007-12-21 2009-09-30 Astrazeneca Ab Nueva forma cristalina b del acido (2r)-(3-amino-2-fluoropropil)fosfinico
WO2009082344A1 (en) * 2007-12-21 2009-07-02 Astrazeneca Ab Novel process for making (2r)-(3-amino-2-fluoropropyl)phosphinic acid form a
WO2009145716A1 (en) * 2008-05-28 2009-12-03 Astrazeneca Ab New pharmaceutical formulation useful in gerd therapy
US9139714B2 (en) 2008-11-05 2015-09-22 Clariant Finance (Bvi) Limited Method for producing dialkylphosphinic acids and esters and salts thereof by means of allyl alcohols-acroleins and use thereof
DE102008056341A1 (de) 2008-11-07 2010-05-12 Clariant International Limited Verfahren zur Herstellung von monoaminofunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Acrylnitrilen und ihre Verwendung
ES2525550T3 (es) 2008-11-07 2014-12-26 Clariant Finance (Bvi) Limited Procedimiento para la preparación de ácidos, ésteres y sales dialquilfosfínicos mediante derivados del ácido acrílico y su uso
WO2010054722A1 (de) 2008-11-11 2010-05-20 Clariant International Ltd Verfahren zur herstellung von mono-allylfunktionalisierten dialkylphosphinsäuren, deren salze und ester mit allylischen verbindungen und ihre verwendung
DE102008060035A1 (de) 2008-12-02 2010-06-10 Clariant International Limited Verfahren zur Herstellung von mono-hydroxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Vinylester einer Carbonsäure und ihre Verwendung
DE102008060535A1 (de) 2008-12-04 2010-06-10 Clariant International Limited Verfahren zur Herstellung von mono-carboxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Vinylether und ihre Verwendung
EP2379573B1 (de) 2008-12-18 2013-12-11 Clariant Finance (BVI) Limited Verfahren zur herstellung von ethylendialkylphosphinsäuren, -estern und -salzen mittels acetylen und ihre verwendung
DE102008063668A1 (de) 2008-12-18 2010-07-01 Clariant International Limited Verfahren zur Herstellung von Alkylphosponsäuren, -estern und -salzen mittels Oxidation von Alkylphosphonigsäuren und ihre Verwendung
DE102008063642A1 (de) 2008-12-18 2010-06-24 Clariant International Limited Verfahren zur Herstellung von monocarboxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Alkylenoxiden und ihre Verwendung
DE102008063627A1 (de) 2008-12-18 2010-06-24 Clariant International Limited Verfahren zur Herstellung von monohydroxyfunktionalisierten Dialkylphosphinsäuren,-estern und -salzen mittels Ethylenoxid und ihre Verwendung
DE102008064003A1 (de) 2008-12-19 2010-06-24 Clariant International Limited Verfahren zur Herstellung von mono-funktionalisierten Dialkylphosphinsäuren, -estern und -salzen und ihre Verwendung
WO2011113904A1 (en) 2010-03-17 2011-09-22 INSERM (Institut National de la Santé et de la Recherche Médicale) Medicaments for the prevention and treatment of a disease associated with retinal ganglion cell degeneration
US20120016021A1 (en) 2010-07-15 2012-01-19 Xenoport, Inc. Methods of treating fragile x syndrome, down's syndrome, autism and related disorders

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CH449046A (de) 1963-07-09 1967-12-31 Ciba Geigy Verfahren zur Herstellung neuer Aminosäuren
GB8425872D0 (en) * 1984-10-12 1984-11-21 Ciba Geigy Ag Chemical compounds
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US5281747A (en) 1989-05-13 1994-01-25 Ciba-Geigy Corporation Substituted aminoalkylphosphinic acids
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US5006560A (en) 1989-12-20 1991-04-09 Schering Corporation Use of GABA-B selective agonists as anti-tussive agents
IL98502A (en) * 1990-06-22 1998-04-05 Ciba Geigy Ag History of Aminoalkene Phosphine Acid, Process for Their Preparation and Pharmaceutical Preparations Containing Them
FR2663934B1 (fr) 1990-06-27 1994-06-03 Adir Nouveaux derives de l'acide 4 - amino butyrique, leur procede de preparation et les preparations pharmaceutiques qui les contiennent.
GB9125615D0 (en) * 1991-12-02 1992-01-29 Wyeth John & Brother Ltd Amines
AU662404B2 (en) * 1992-05-08 1995-08-31 Novartis Ag Novel N-aralkyl- and N-heteroaralkyl-aminoalkanephosphinic acids
FR2722192A1 (fr) 1994-07-06 1996-01-12 Adir Nouveaux derives de l'acide 4-amino butyrique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
GB9420784D0 (en) 1994-10-14 1994-11-30 Glaxo Group Ltd Medicaments
SE9603408D0 (sv) 1996-09-18 1996-09-18 Astra Ab Medical use
US7319095B2 (en) * 1999-12-09 2008-01-15 Astrazeneca Ab Use of GABAB receptor agonists
SE9904507D0 (sv) * 1999-12-09 1999-12-09 Astra Ab New compounds
SE9904508D0 (sv) * 1999-12-09 1999-12-09 Astra Ab New compounds

Also Published As

Publication number Publication date
US20050137414A1 (en) 2005-06-23
MY125414A (en) 2006-07-31
CZ20021983A3 (cs) 2002-11-13
EE05067B1 (et) 2008-08-15
ZA200204127B (en) 2003-08-25
JP3914435B2 (ja) 2007-05-16
US20080146836A1 (en) 2008-06-19
PL364795A1 (en) 2004-12-13
SE9904508D0 (sv) 1999-12-09
CN1409716A (zh) 2003-04-09
US20030220303A1 (en) 2003-11-27
CN1198832C (zh) 2005-04-27
DE60015796T2 (de) 2005-11-03
NO20022728L (no) 2002-08-07
SI1240172T1 (en) 2005-02-28
US6841698B2 (en) 2005-01-11
RU2002113909A (ru) 2004-01-10
DK1240172T3 (da) 2005-02-14
UA71649C2 (en) 2004-12-15
CA2397583A1 (en) 2001-06-14
AU2036401A (en) 2001-06-18
US6576626B2 (en) 2003-06-10
HUP0300301A2 (hu) 2003-06-28
JP2006306885A (ja) 2006-11-09
US7807658B2 (en) 2010-10-05
ATE282043T1 (de) 2004-11-15
NO329595B1 (no) 2010-11-22
KR20020060992A (ko) 2002-07-19
KR100689144B1 (ko) 2007-03-08
IL149840A0 (en) 2002-11-10
BR0016253A (pt) 2002-08-27
IS6408A (is) 2002-06-06
US7034176B2 (en) 2006-04-25
CA2397583C (en) 2010-11-09
MXPA02005536A (es) 2004-09-10
TWI228510B (en) 2005-03-01
PL201789B1 (pl) 2009-05-29
PT1240172E (pt) 2005-02-28
HK1048321A1 (en) 2003-03-28
RU2260595C2 (ru) 2005-09-20
HK1048321B (zh) 2005-09-30
SK286904B6 (sk) 2009-07-06
NZ519376A (en) 2003-11-28
SK7642002A3 (en) 2002-12-03
ES2230174T3 (es) 2005-05-01
US20020156053A1 (en) 2002-10-24
EE200200286A (et) 2003-08-15
DE60015796D1 (de) 2004-12-16
EP1240172B1 (en) 2004-11-10
HK1053125A1 (en) 2003-10-10
US20070021393A1 (en) 2007-01-25
AR030541A1 (es) 2003-08-27
EP1484333A1 (en) 2004-12-08
IS2231B (is) 2007-04-15
JP2003516407A (ja) 2003-05-13
AU780459B2 (en) 2005-03-24
WO2001042252A1 (en) 2001-06-14
EP1240172A1 (en) 2002-09-18
HUP0300301A3 (en) 2008-12-29
IL149840A (en) 2006-04-10

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