[go: up one dir, main page]

NO20015832L - Trisykliske kondenserte heterosyklus-forbindelser, fremgangsmåte for deres fremstilling og anvendelse derav - Google Patents

Trisykliske kondenserte heterosyklus-forbindelser, fremgangsmåte for deres fremstilling og anvendelse derav

Info

Publication number
NO20015832L
NO20015832L NO20015832A NO20015832A NO20015832L NO 20015832 L NO20015832 L NO 20015832L NO 20015832 A NO20015832 A NO 20015832A NO 20015832 A NO20015832 A NO 20015832A NO 20015832 L NO20015832 L NO 20015832L
Authority
NO
Norway
Prior art keywords
processes
preparation
inhibition
independently
alkyl group
Prior art date
Application number
NO20015832A
Other languages
English (en)
Norwegian (no)
Other versions
NO20015832D0 (no
Inventor
Shuji Jinno
Takaaki Okita
Naomi Ohtsuka
Shinya Yamashita
Junichiro Hata
Jiro Takeo
Original Assignee
Nippon Suisan Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Suisan Kaisha Ltd filed Critical Nippon Suisan Kaisha Ltd
Publication of NO20015832D0 publication Critical patent/NO20015832D0/no
Publication of NO20015832L publication Critical patent/NO20015832L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/305—Mercury compounds
    • A61K31/31—Mercury compounds containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/14—[b,f]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D337/14—[b,f]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NO20015832A 1999-06-03 2001-11-29 Trisykliske kondenserte heterosyklus-forbindelser, fremgangsmåte for deres fremstilling og anvendelse derav NO20015832L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP15718199 1999-06-03
PCT/JP2000/003592 WO2000075127A1 (fr) 1999-06-03 2000-06-02 Composes heterocycliques condenses a trois cycles, procede de preparation correspondant et utilisation de tels composes

Publications (2)

Publication Number Publication Date
NO20015832D0 NO20015832D0 (no) 2001-11-29
NO20015832L true NO20015832L (no) 2002-02-01

Family

ID=15643970

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20015832A NO20015832L (no) 1999-06-03 2001-11-29 Trisykliske kondenserte heterosyklus-forbindelser, fremgangsmåte for deres fremstilling og anvendelse derav

Country Status (22)

Country Link
US (3) US6602898B1 (es)
EP (1) EP1182200B1 (es)
JP (1) JP3471778B2 (es)
KR (1) KR20020016812A (es)
CN (1) CN1192027C (es)
AT (1) ATE303376T1 (es)
AU (1) AU777414B2 (es)
BG (1) BG106169A (es)
BR (1) BR0011529A (es)
CA (1) CA2370013A1 (es)
CZ (1) CZ20014261A3 (es)
DE (1) DE60022341T2 (es)
DK (1) DK1182200T3 (es)
ES (1) ES2248080T3 (es)
HU (1) HUP0201203A3 (es)
IL (1) IL146732A0 (es)
NO (1) NO20015832L (es)
NZ (1) NZ515666A (es)
PL (1) PL352840A1 (es)
RU (1) RU2211837C2 (es)
WO (1) WO2000075127A1 (es)
ZA (1) ZA200109565B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0415320D0 (en) * 2004-07-08 2004-08-11 Astrazeneca Ab Novel compounds
JP5773585B2 (ja) * 2009-06-29 2015-09-02 日東電工株式会社 発光性トリアリール
TWI698430B (zh) 2015-02-13 2020-07-11 南北兄弟藥業投資有限公司 三環化合物及其在藥物中的應用
TW201808283A (zh) * 2016-08-05 2018-03-16 廣東東陽光藥業有限公司 含氮三環化合物及其在藥物中的應用
WO2018082596A1 (en) 2016-11-03 2018-05-11 Sunshine Lake Pharma Co., Ltd. Solid forms of an adamantyl compound, compositions and uses thereof
CN110128432B (zh) * 2018-02-02 2021-03-02 广东东阳光药业有限公司 含氮三环化合物及其在药物中的应用
CN118271327A (zh) * 2022-12-30 2024-07-02 广东东阳光药业股份有限公司 三环化合物的晶型及其用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1302590B (es) 1966-08-03 1970-11-12
US4104280A (en) 1977-02-04 1978-08-01 Syntex (U.S.A.) Inc. Dibenzo [b.f]thiepin and dibenzo[b.f]oxepin derivatives
PT68303A (en) 1977-07-26 1978-08-01 Merck & Co Inc Process for the preparation of dibenzo/b,f/thiepin
JPS54122284A (en) 1978-02-17 1979-09-21 Dainippon Pharmaceut Co Ltd Dibenzb,foxepin derivative
JPS54115388A (en) 1978-03-01 1979-09-07 Nippon Chemiphar Co Ltd Acetic acid derivative and its preparation
US4237160A (en) 1979-11-27 1980-12-02 Merck Sharp & Dohme (I.A.) Corp. 3-Hydroxymethyldibenzo[b,f]thiepins as prostaglandin antagonists
DE3203065A1 (de) 1982-01-30 1983-08-04 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von dibenzoxepinonen
FR2693655B1 (fr) 1992-07-20 1994-10-14 Virbac Vaccin antirabique avirulent.
EP0805155B1 (en) 1994-09-28 2002-03-13 Nippon Suisan Kaisha, Ltd. Novel antioxidant tricyclic fused heterocyclic compound
ATE203528T1 (de) 1995-02-08 2001-08-15 Novartis Erfind Verwalt Gmbh Antineurodegenerativ wirksame 10-aminoaliphatyl- dibenz- b,f oxepine
WO1996025927A1 (fr) 1995-02-22 1996-08-29 Nippon Suisan Kaisha, Ltd. Inhibiteur des recepteurs de l'acide glutamique et ameliorant des fonctions cerebrales
WO1997025985A1 (fr) * 1996-01-19 1997-07-24 Nippon Suisan Kaisha, Ltd. Relaxant des muscles lisses de la trachee
JPH10204079A (ja) * 1997-01-20 1998-08-04 Nippon Suisan Kaisha Ltd ジベンゾオキセピンおよびジベンゾチエピン誘導体の製造方法
HUP0002461A3 (en) * 1997-04-15 2003-01-28 Kyowa Hakko Kogyo Kk Tricyclic benzothiepin a benzoxepin derivatives and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
ES2248080T3 (es) 2006-03-16
BG106169A (bg) 2002-05-31
EP1182200B1 (en) 2005-08-31
US6602898B1 (en) 2003-08-05
PL352840A1 (en) 2003-09-08
US20040127713A1 (en) 2004-07-01
US20030220360A1 (en) 2003-11-27
BR0011529A (pt) 2002-12-17
WO2000075127A1 (fr) 2000-12-14
US6700013B2 (en) 2004-03-02
IL146732A0 (en) 2002-07-25
KR20020016812A (ko) 2002-03-06
AU5104400A (en) 2000-12-28
DE60022341T2 (de) 2006-06-29
CN1192027C (zh) 2005-03-09
WO2000075127A8 (fr) 2001-03-15
HUP0201203A2 (en) 2002-08-28
RU2211837C2 (ru) 2003-09-10
DE60022341D1 (de) 2005-10-06
US7410997B2 (en) 2008-08-12
CN1353703A (zh) 2002-06-12
CZ20014261A3 (cs) 2002-06-12
AU777414B2 (en) 2004-10-14
JP3471778B2 (ja) 2003-12-02
EP1182200A1 (en) 2002-02-27
NO20015832D0 (no) 2001-11-29
NZ515666A (en) 2003-10-31
DK1182200T3 (da) 2005-12-27
HUP0201203A3 (en) 2004-12-28
ZA200109565B (en) 2003-04-11
EP1182200A9 (en) 2002-05-22
CA2370013A1 (en) 2000-12-14
ATE303376T1 (de) 2005-09-15

Similar Documents

Publication Publication Date Title
DE69736642D1 (de) Heterocyclische Verbindungen, ihre Herstellung und Verwendung
PT89575A (pt) Metodo para reforcar a memoria ou corrigir as deficiencias de memoria utilizando arilamido (e ariltioamido)-azabicicloalcanos
CA2313122A1 (en) Bicycliccarbonyl indole compounds as anti-inflammatory/analgesic agents
GR3020848T3 (en) 1,8-Naphthyridin-2-one derivatives
HU904785D0 (en) Process for the production of medicaments
NO913725D0 (no) Benzen-, pyridin- og pyrimidin-derivater og fremgangsmaatefor deres fremstilling.
NO20015832L (no) Trisykliske kondenserte heterosyklus-forbindelser, fremgangsmåte for deres fremstilling og anvendelse derav
MX9202736A (es) [(arilalquilpiperidin-4-il)metil)]-2a,3,4,5,-tetrahidro-1(2h)-acenafti len-1-onas y compuestos afines, un procedimiento para su preparacion y su empleo como medicamentos.
NO941150L (no) Tiadiazinoner
IE852866L (en) Thienopyridine derivatives
ATE302199T1 (de) Quinalozinon-derivate
YU80689A (en) Hetero-tetracyclical lactame derivatives
ATE11045T1 (de) In 3-stellung durch aryl substituierte 7-chlor3,4-dihydro-1,9(2h,10h)- und -10hydroxyacridindionimine, verfahren zu ihrer herstellung und diese acridindionimine enthaltende pharmazeutische zusammensetzungen.
DK0570850T3 (da) Benzo(b)thiophen-3-yl-piperaziner, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler
EP1346987A4 (en) BENZOFURANE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
GR70356B (es)
NZ220294A (en) Heteropolycyclic aromatic amines and pharmaceutical compositions thereof
DE60239324D1 (de) Phenyl- und pyridyl-piperidine mit tnf-wirkung
DE69828037D1 (de) Pyrroloindol-derivate und zwischenprodukte zu ihrer herstellung
UA35545C2 (uk) Спосіб одержання похідних 4-оксохіноліну або хромону

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application