NO20012310D0 - Optisk aktiv pyridyl-4H-1,2,4-oksazdiazinderivat og dets anvendelse ved behandling av karsykdommer - Google Patents

Optisk aktiv pyridyl-4H-1,2,4-oksazdiazinderivat og dets anvendelse ved behandling av karsykdommer

Info

Publication number: NO20012310D0
Authority: NO; Norway
Prior art keywords: oxazdiazine; derivative; treatment; optically active; vascular disease
Prior art date: 1998-12-14

Application number

NO20012310A

Other languages

English (en)

Other versions

NO317649B1 (no

NO20012310L (no

Inventor

Andrea Jednakovits

Laszlo Ueroegdi

Laszlo Denes

Istvan Kurucz

Ede Marvanyos

Mihaly Barabas

Ernoe Bacsy

Zsuzsanna Korom

Zoltan Nagy

Laszlo Uerge

Jenoe Szilbereky

Karoly Acsai

Peter Krajcsi

Zita Csakai

Magdolna Toeroek

Original Assignee

Biorex Kutato Fejlesztoe Kft

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-14

Filing date

2001-05-10

Publication date

2001-05-10

2001-05-10 Application filed by Biorex Kutato Fejlesztoe Kft filed Critical Biorex Kutato Fejlesztoe Kft

2001-05-10 Publication of NO20012310D0 publication Critical patent/NO20012310D0/no

2001-05-10 Publication of NO20012310L publication Critical patent/NO20012310L/no

2004-11-29 Publication of NO317649B1 publication Critical patent/NO317649B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5355—Non-condensed oxazines and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Heart & Thoracic Surgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO20012310A 1998-12-14 2001-05-10 Optisk aktiv pyridyl-4H-1,2,4-oksazdiazinderivat og dets anvendelse ved behandling av karsykdommer NO317649B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
HU9802897A HU226617B1 (en)	1998-12-14	1998-12-14	Optically active pyridyl-4h-1,2,4-oxadiazine derivatives, and pharmaceutical composition containing the compound as active ingredient
PCT/HU1999/000095 WO2000035914A1 (en)	1998-12-14	1999-12-07	Optically active pyridyl-4h-1,2,4-oxadiazine derivative and its use in the treatment of vascular diseases

Publications (3)

Publication Number	Publication Date
NO20012310D0 true NO20012310D0 (no)	2001-05-10
NO20012310L NO20012310L (no)	2001-05-10
NO317649B1 NO317649B1 (no)	2004-11-29

Family

ID=10991166

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20012310A NO317649B1 (no)	1998-12-14	2001-05-10	Optisk aktiv pyridyl-4H-1,2,4-oksazdiazinderivat og dets anvendelse ved behandling av karsykdommer

Country Status (27)

Country	Link
US (1)	US6384029B1 (no)
EP (1)	EP1147105B1 (no)
JP (2)	JP2002532498A (no)
KR (1)	KR100661774B1 (no)
AT (1)	ATE266027T1 (no)
AU (1)	AU765336B2 (no)
BG (1)	BG65179B1 (no)
BR (1)	BR9913982A (no)
CA (1)	CA2340734C (no)
CZ (1)	CZ300764B6 (no)
DE (1)	DE69917074T2 (no)
DK (1)	DK1147105T3 (no)
EE (1)	EE04551B1 (no)
ES (1)	ES2219091T3 (no)
HR (1)	HRP20010133B1 (no)
HU (1)	HU226617B1 (no)
IL (1)	IL141515A (no)
NO (1)	NO317649B1 (no)
PL (1)	PL196584B1 (no)
PT (1)	PT1147105E (no)
RS (1)	RS50129B (no)
RU (1)	RU2222538C2 (no)
SI (1)	SI1147105T1 (no)
SK (1)	SK285582B6 (no)
UA (1)	UA70340C2 (no)
WO (1)	WO2000035914A1 (no)
ZA (1)	ZA200101182B (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2003202104B8 (en)	2002-01-11	2008-10-02	Cytrx Corporation	Carboxamidine derivatives and their use in the treatment of vascular diseases
KR100678577B1 (ko) *	2006-09-11	2007-02-06	조만규	가정용 분전함
EP3031467B1 (en)	2008-06-26	2019-03-06	Orphazyme A/S	Use of hsp70 as a regulator of enzymatic activity
BRPI0919867A2 (pt)	2008-11-18	2015-12-15	Santen Pharmaceutical Co Ltd	agente terapeutico ou profilatico para uma doenca degenerativa coriorretiniana, e metodo profilatico ou terapeutico para uma doenca degenerativa coriorrentiniana
EP2646044B1 (en)	2010-11-30	2019-08-28	Orphazyme A/S	Methods for increasing intracellular activity of hsp70
HUP1100534A2 (en)	2011-09-26	2013-04-29	Balazs Dr Hazay	Pharmaceutical composition for the treatment of muscle atrophy
CA2961097C (en)	2014-09-15	2023-09-26	Orphazyme Aps	Extended-release pharmaceutical formulation comprising arimoclomol
EP3442530A1 (en)	2016-04-13	2019-02-20	Orphazyme A/S	Heat shock proteins and cholesterol homeostasis
BR112018070653A2 (pt)	2016-04-29	2019-02-05	Orphazyme As	ingrediente farmacêutico ativo, e, composição
EP3630105A1 (en)	2017-05-24	2020-04-08	Orphazyme A/S	Heat shock protein inducers and frontotemporal disorders
AU2019276048A1 (en)	2018-05-28	2021-01-21	Zevra Denmark A/S	Hsp70 protein levels in PBMC samples as biomarker for disease
CA3202568A1 (en)	2020-11-19	2022-05-27	Zevra Denmark A/S	Processes for preparing arimoclomol citrate and intermediates thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AT395853B (de) *	1991-01-31	1993-03-25	Chem Pharm Forsch Gmbh	Neue imidazolderivate, verfahren zu ihrer herstellung und ihre verwendung
HU222994B1 (hu) *	1995-11-02	2004-01-28	BIOREX Kutató és Fejlesztő Rt.	Hidroxilaminszármazékok és azok alkalmazása sejtek molekuláris chaperon-termelésének fokozására alkalmas gyógyszerkészítmények előállítására
DE69628320D1 (de) *	1995-11-03	2003-06-26	Summit Packaging Systems Ltd	Vorrichtung zum abgeben und füllen von beuteln an einem kassenplatz eines supermarkts
UA64716C2 (en) *	1996-08-09	2004-03-15		Pharmaceuticals for therapy or prevention of illnesses connected with dysfunction of vascular endothelial cells

1998
- 1998-12-14 HU HU9802897A patent/HU226617B1/hu not_active IP Right Cessation
1999
- 1999-07-12 UA UA2001063850A patent/UA70340C2/uk unknown
- 1999-12-07 EP EP99961225A patent/EP1147105B1/en not_active Expired - Lifetime
- 1999-12-07 US US09/762,949 patent/US6384029B1/en not_active Expired - Lifetime
- 1999-12-07 SI SI9930566T patent/SI1147105T1/xx unknown
- 1999-12-07 AT AT99961225T patent/ATE266027T1/de active
- 1999-12-07 WO PCT/HU1999/000095 patent/WO2000035914A1/en active IP Right Grant
- 1999-12-07 EE EEP200100188A patent/EE04551B1/xx not_active IP Right Cessation
- 1999-12-07 CA CA002340734A patent/CA2340734C/en not_active Expired - Lifetime
- 1999-12-07 PT PT99961225T patent/PT1147105E/pt unknown
- 1999-12-07 DE DE69917074T patent/DE69917074T2/de not_active Expired - Lifetime
- 1999-12-07 IL IL14151599A patent/IL141515A/xx not_active IP Right Cessation
- 1999-12-07 JP JP2000588174A patent/JP2002532498A/ja not_active Withdrawn
- 1999-12-07 CZ CZ20011550A patent/CZ300764B6/cs not_active IP Right Cessation
- 1999-12-07 SK SK234-2001A patent/SK285582B6/sk not_active IP Right Cessation
- 1999-12-07 ES ES99961225T patent/ES2219091T3/es not_active Expired - Lifetime
- 1999-12-07 RS YUP-250/01A patent/RS50129B/sr unknown
- 1999-12-07 DK DK99961225T patent/DK1147105T3/da active
- 1999-12-07 PL PL346767A patent/PL196584B1/pl not_active IP Right Cessation
- 1999-12-07 BR BR9913982-0A patent/BR9913982A/pt not_active Application Discontinuation
- 1999-12-07 KR KR1020017002870A patent/KR100661774B1/ko not_active Expired - Fee Related
- 1999-12-07 HR HR20010133A patent/HRP20010133B1/xx not_active IP Right Cessation
- 1999-12-07 RU RU2001118854/04A patent/RU2222538C2/ru not_active IP Right Cessation
- 1999-12-07 AU AU17906/00A patent/AU765336B2/en not_active Expired
2001
- 2001-02-12 ZA ZA200101182A patent/ZA200101182B/en unknown
- 2001-03-14 BG BG105342A patent/BG65179B1/bg unknown
- 2001-05-10 NO NO20012310A patent/NO317649B1/no not_active IP Right Cessation
2011
- 2011-06-08 JP JP2011128516A patent/JP5620340B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
PL196584B1 (pl)	2008-01-31
CZ20011550A3 (cs)	2001-08-15
EP1147105A1 (en)	2001-10-24
JP2002532498A (ja)	2002-10-02
EE200100188A (et)	2002-08-15
AU1790600A (en)	2000-07-03
EP1147105B1 (en)	2004-05-06
IL141515A0 (en)	2002-03-10
KR20010073129A (ko)	2001-07-31
UA70340C2 (en)	2004-10-15
DE69917074D1 (de)	2004-06-09
US6384029B1 (en)	2002-05-07
JP2011201916A (ja)	2011-10-13
HRP20010133B1 (en)	2005-02-28
BR9913982A (pt)	2001-06-12
WO2000035914A1 (en)	2000-06-22
KR100661774B1 (ko)	2006-12-28
ATE266027T1 (de)	2004-05-15
CZ300764B6 (cs)	2009-08-05
NO317649B1 (no)	2004-11-29
YU25001A (sh)	2004-07-15
RU2222538C2 (ru)	2004-01-27
SI1147105T1 (en)	2004-08-31
CA2340734C (en)	2008-10-21
EE04551B1 (et)	2005-10-17
CA2340734A1 (en)	2000-06-22
HUP9802897A2 (hu)	2000-11-28
SK2342001A3 (en)	2001-08-06
IL141515A (en)	2005-09-25
PT1147105E (pt)	2004-07-30
JP5620340B2 (ja)	2014-11-05
HU9802897D0 (en)	1999-02-01
HUP9802897A3 (en)	2001-08-28
RS50129B (sr)	2009-03-25
DE69917074T2 (de)	2005-05-12
PL346767A1 (en)	2002-02-25
BG65179B1 (bg)	2007-05-31
HRP20010133A2 (en)	2002-02-28
AU765336B2 (en)	2003-09-18
DK1147105T3 (da)	2004-06-01
BG105342A (en)	2001-12-29
NO20012310L (no)	2001-05-10
HU226617B1 (en)	2009-04-28
ZA200101182B (en)	2002-02-12
SK285582B6 (sk)	2007-04-05
ES2219091T3 (es)	2004-11-16

Publication	Publication Date	Title
GB0005251D0 (en)	2000-04-26	Therapeutic compounds
BG106825A (en)	2003-02-28	Substituted oxazolidinones and their use in the field of blood coagulation
EE03969B1 (et)	2003-02-17	(Metüülsulfonüül)fenüül-2-(5H)-furanoonid, nende kasutamine ja farmatseutilised kompositsioonid
EE200000535A (et)	2002-04-15	Triasendatud 1,3,5-triasiini derivaatide kasutamine ravimi valmistamiseks, mis on ette nähtud HIV nakkuse raviks, ühend, seda sisaldav farmatseutiline kompositsioon, meetod ühendi ja kompositsiooni valmistamiseks ning kombineeritud preparaat kasutami
MY106315A (en)	1995-04-29	Pharmaceutical agents
NO324227B1 (no)	2007-09-10	Cyclopropyl-kondenserte pyrrolidin-baserte forbindelser, farmasoytiske blandinger og kombinasjoner inneholdende slike samt anvendelse av slike for fremstilling av medikamenter for behandling av sykdommer
NO20053644L (no)	2002-10-22	(2S)-2-[(4S)-4-(2,2-difluorvinyl)-2-oksopyrrolidinyl ]butanamid og farmasoytisk preparat
SE7903186L (sv)	1979-10-12	Cerebralverksamt medel
NO20012310D0 (no)	2001-05-10	Optisk aktiv pyridyl-4H-1,2,4-oksazdiazinderivat og dets anvendelse ved behandling av karsykdommer
ATE322878T1 (de)	2006-04-15	Biotin enthaltende galenische formulierung
CY1105545T1 (el)	2010-07-28	Θεραπεια στατινης για ενισχυση της διατηρησης νοητικης λειτουργιας
TR199901385T2 (xx)	1999-11-22	Piperidin t�revleri.
HUP0000110A2 (hu)	2000-06-28	Azaciklusos, azabiciklusos vagy tetrahidropiridinszármazékokat tartalmazó, fájdalom kezelésére alkalmas gyógyászati készítmények
DK0561882T3 (da)	1994-10-03	Hydroxamsyrederivater, som inhiberer lipoxygenase
ATE555787T1 (de)	2012-05-15	Behandlungseffekte von überschüssigen reaktiven sauerstoffspezies
FR2673105B1 (fr)	1995-01-13	Nouvelles compositions pharmaceutiques, notamment pour le traitement des colopathies fonctionnelles, et procedes de preparation de compositions et de medicaments, notamment pour le traitement de ces affections.
HUP9802896A3 (en)	2001-08-28	Optically active piperidinoalkyl-4h-1,2,4-oxadiazine derivative, the use thereof in the treatment of vascular diseases and pharmaceutical composition containing the compound as active ingredient
FR2804867B1 (fr)	2002-09-20	Application de derives de xanthine pour la preparation d'un medicament destine a la prevention ou au traitement de l'osteoporose
UA30143C2 (uk)	2001-11-15	Лікувальний препарат для профілактики та лікування інфекційних та запальних захворювань

Legal Events

Date	Code	Title	Description
2012-07-23	MM1K	Lapsed by not paying the annual fees