NO20006255D0 - Krystallinsk efavirenz - Google Patents

Krystallinsk efavirenz

Info

Publication number: NO20006255D0
Authority: NO; Norway
Prior art keywords: crystalline efavirenz; efavirenz; crystalline
Prior art date: 1998-06-11

Application number

NO20006255A

Other languages

English (en)

Other versions

NO20006255L (no

Inventor

Lilian Alicia Radesca

Michael B Maurin

Shelley R Rabel

James R Moore

Original Assignee

Du Pont Pharm Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-06-11

Filing date

2000-12-08

Publication date

2000-12-08

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22214647&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20006255(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2000-12-08 Application filed by Du Pont Pharm Co filed Critical Du Pont Pharm Co

2000-12-08 Publication of NO20006255D0 publication Critical patent/NO20006255D0/no

2001-02-12 Publication of NO20006255L publication Critical patent/NO20006255L/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/18—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Virology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
AIDS & HIV (AREA)
Engineering & Computer Science (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

NO20006255A 1998-06-11 2000-12-08 Krystallinsk efavirenz NO20006255L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US8898198P	1998-06-11	1998-06-11
PCT/US1999/013199 WO1999064405A1 (en)	1998-06-11	1999-06-10	Crystalline efavirenz

Publications (2)

Publication Number	Publication Date
NO20006255D0 true NO20006255D0 (no)	2000-12-08
NO20006255L NO20006255L (no)	2001-02-12

Family

ID=22214647

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20006255A NO20006255L (no)	1998-06-11	2000-12-08	Krystallinsk efavirenz

Country Status (21)

Country	Link
EP (1)	EP1086087A1 (no)
JP (1)	JP2002517487A (no)
CN (1)	CN1307568A (no)
AR (3)	AR018670A1 (no)
AU (1)	AU758114C (no)
BR (1)	BR9911523A (no)
CA (1)	CA2333550A1 (no)
EE (1)	EE05547B1 (no)
HR (1)	HRP990182A2 (no)
HU (1)	HUP0103819A3 (no)
IL (1)	IL139793A (no)
MY (1)	MY126450A (no)
NO (1)	NO20006255L (no)
NZ (1)	NZ507713A (no)
PL (1)	PL198504B1 (no)
SG (3)	SG111981A1 (no)
SK (1)	SK18182000A3 (no)
TW (1)	TWI235152B (no)
UA (1)	UA74324C2 (no)
WO (1)	WO1999064405A1 (no)
ZA (1)	ZA200006173B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5965729A (en)	1997-02-05	1999-10-12	Merck & Co., Inc.	Process for the crystallization of a reverse transcriptase inhibitor using an anti-solvent
WO2006018853A2 (en)	2004-08-19	2006-02-23	Hetero Drugs Limited	Novel polymorphs of efavirenz
US7205402B2 (en) *	2004-09-02	2007-04-17	Bristol-Myers Squibb Company	Synthesis of a benzoxazinone
WO2008108630A1 (en) *	2007-03-02	2008-09-12	Ultimorphix Technologies B.V.	Polymorphic forms of efavirenz
WO2009011567A1 (en) *	2007-07-16	2009-01-22	Ultimorphix Technologies B.V.	Crystalline forms of efavirenz
AU2009211072B2 (en)	2008-02-04	2014-01-23	Pfizer Limited	Polymorphic form of a [1, 2, 4] triazolo [4, 3-A] pyridine derivative for treating inflammatory diseases
WO2010073254A2 (en)	2008-12-22	2010-07-01	Hetero Research Foundation	Process for preparing efavirenz polymorph
DE102009041443A1 (de)	2009-09-16	2011-03-31	Archimica Gmbh	Salze des 6-Chlor-4-(cyclopropylethinyl)-1,4-dihydro-4-(trifluormethyl)-2H-3,1-benzoxazin-2-ons und deren Synthese, Aufreinigung und Anwendung als Vorstufen für Efavirenz
EP2471783A1 (en)	2010-12-23	2012-07-04	Esteve Química, S.A.	Novel polymorphic form of efavirenz
CN103508973B (zh) *	2012-06-25	2016-04-27	上海迪赛诺药业有限公司	制备依非韦伦i型结晶的方法
CN102924398B (zh) *	2012-11-22	2015-11-18	安徽贝克生物制药有限公司	用于除去依非韦伦对应异构体的方法
US9468646B2 (en)	2013-01-23	2016-10-18	Alienor Farma	Increased dosage of efavirenz for the treatment of cancer
CN105037175B (zh) *	2014-07-18	2017-02-22	盐城迪赛诺制药有限公司	一种用于提高依非韦伦中间体光学纯度的方法
CN105001101B (zh) *	2015-05-28	2017-11-28	乐平市瑞盛制药有限公司	一种4‑氯‑2‑三氟乙酰基苯胺水合物盐酸盐的合成方法
CN108947855B (zh) *	2018-08-10	2021-10-22	江苏沙星化工有限公司	一种依非韦伦关键中间体的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL106507A (en) *	1992-08-07	1997-11-20	Merck & Co Inc	Pharmaceutical compositions containing benzoxazinones and some novel compounds of this type
AU1694295A (en) *	1994-01-28	1995-08-15	Merck & Co., Inc.	Benzoxazinones as inhibitors of hiv reverse transcriptase
US5633405A (en) *	1995-05-25	1997-05-27	Merck & Co., Inc.	Asymmetric synthesis of (-)-6-chloro-4-cyclopropyl-ethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxanzin-2-one
AU3736197A (en) *	1996-07-26	1998-02-20	Du Pont Pharmaceuticals Company	A practical synthesis of benzoxazinones useful as hiv reverse transcripta se inhibitors
EP0929533B1 (en) *	1996-10-02	2003-09-03	Bristol-Myers Squibb Pharma Company	4,4-disubstituted-1,4-dihydro-2h-3,1-benzoxazin-2-ones useful as hiv reverse transcriptase inhibitors and intermediates and processes for making the same
CZ304186B6 (cs) *	1997-02-05	2013-12-11	Merck Sharp & Dohme Corp.	Krystalická forma I inhibitoru na bázi benzoxazinu a zpusob její výroby

1999
- 1999-06-08 HR HR60/088,981A patent/HRP990182A2/hr not_active Application Discontinuation
- 1999-06-10 IL IL139793A patent/IL139793A/en not_active IP Right Cessation
- 1999-06-10 UA UA2000127048A patent/UA74324C2/uk unknown
- 1999-06-10 NZ NZ507713A patent/NZ507713A/en not_active IP Right Cessation
- 1999-06-10 AU AU44364/99A patent/AU758114C/en not_active Expired
- 1999-06-10 HU HU0103819A patent/HUP0103819A3/hu unknown
- 1999-06-10 EP EP99927468A patent/EP1086087A1/en not_active Withdrawn
- 1999-06-10 EE EEP200000743A patent/EE05547B1/xx unknown
- 1999-06-10 WO PCT/US1999/013199 patent/WO1999064405A1/en not_active Ceased
- 1999-06-10 SG SG200207221A patent/SG111981A1/en unknown
- 1999-06-10 SG SG200207226-2A patent/SG134977A1/en unknown
- 1999-06-10 PL PL345221A patent/PL198504B1/pl unknown
- 1999-06-10 JP JP2000553414A patent/JP2002517487A/ja active Pending
- 1999-06-10 MY MYPI99002384A patent/MY126450A/en unknown
- 1999-06-10 SG SG200207220A patent/SG111980A1/en unknown
- 1999-06-10 CN CN99807219A patent/CN1307568A/zh active Pending
- 1999-06-10 CA CA002333550A patent/CA2333550A1/en not_active Abandoned
- 1999-06-10 BR BR9911523-9A patent/BR9911523A/pt not_active Application Discontinuation
- 1999-06-10 SK SK1818-2000A patent/SK18182000A3/sk unknown
- 1999-06-11 AR ARP990102809A patent/AR018670A1/es not_active Application Discontinuation
- 1999-07-03 TW TW088109817A patent/TWI235152B/zh not_active IP Right Cessation
2000
- 2000-10-31 ZA ZA200006173A patent/ZA200006173B/xx unknown
- 2000-12-08 NO NO20006255A patent/NO20006255L/no not_active Application Discontinuation
2010
- 2010-07-08 AR ARP100102490A patent/AR077407A2/es not_active Application Discontinuation
- 2010-07-08 AR ARP100102491A patent/AR077469A2/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
NZ507713A (en)	2003-08-29
AR018670A1 (es)	2001-11-28
SG111980A1 (en)	2005-06-29
HUP0103819A2 (hu)	2002-02-28
SG111981A1 (en)	2005-06-29
PL345221A1 (en)	2001-12-03
AR077469A2 (es)	2011-08-31
IL139793A (en)	2006-10-31
UA74324C2 (uk)	2005-12-15
TWI235152B (en)	2005-07-01
PL198504B1 (pl)	2008-06-30
EE05547B1 (et)	2012-06-15
CN1307568A (zh)	2001-08-08
EP1086087A1 (en)	2001-03-28
HRP990182A2 (en)	2000-02-29
IL139793A0 (en)	2002-02-10
MY126450A (en)	2006-10-31
SG134977A1 (en)	2007-09-28
JP2002517487A (ja)	2002-06-18
CA2333550A1 (en)	1999-12-16
AU758114C (en)	2003-10-30
WO1999064405A1 (en)	1999-12-16
AU4436499A (en)	1999-12-30
ZA200006173B (en)	2001-10-31
NO20006255L (no)	2001-02-12
BR9911523A (pt)	2001-09-18
EE200000743A (et)	2002-10-15
AU758114B2 (en)	2003-03-13
AR077407A2 (es)	2011-08-24
HUP0103819A3 (en)	2003-05-28
SK18182000A3 (sk)	2001-08-06

Publication	Publication Date	Title
DE59901560D1 (de)	2002-07-04	Retrograder tibianagel
PT1119430E (pt)	2004-03-31	Fresa
ID23761A (id)	2000-05-11	Trisiklik tersubstitusi
EE200100135A (et)	2002-06-17	EtO2C-CH2-(R)Cgl-Aze-Pab-OH kristalsed vormid
DE59906732D1 (de)	2003-10-02	Verstellmechanismus
ID24221A (id)	2000-07-13	Tempat patrum
NO20006255D0 (no)	2000-12-08	Krystallinsk efavirenz
ATE262513T1 (de)	2004-04-15	Benzoylpyridazine
DE69714228D1 (de)	2002-08-29	Kristalline metallophosphate
ID23219A (id)	2000-03-30	Trisiklik tersubstitusi
FI980222A0 (fi)	1998-01-30	Stycke av isoleringsaemne med en genomgaoende primaerstroemledning
DE59901046D1 (de)	2002-05-02	Methylcyclotetradec-5-en-1-one
PT1102747E (pt)	2003-09-30	Formas cristalinas do osanetant
DE59807217D1 (de)	2003-03-20	Nadellager
DE59808995D1 (de)	2003-08-14	Endomikroskopsystem
DE19842103B4 (de)	2005-03-10	Stanznietzuführung
DE59900612D1 (de)	2002-02-21	Dispersionsazofarbstoffmischungen
DE59902088D1 (de)	2002-08-29	Achrathermer Reimager
FI980856A0 (fi)	1998-04-17	Andningsskydd utrustad med en identifierare
DE59912532D1 (de)	2005-10-13	Substituierte acylaminophenyl-uracile
DE59912188D1 (de)	2005-07-21	Substituierte phenyluracile
PT1076660E (pt)	2002-11-29	(4-bromopirazol-3-il)-benzazolos substituidos
DE59901263D1 (de)	2002-05-23	Einzelplatz-sortierer
FI980053A0 (fi)	1998-01-14	Anordning foer utformande av fiberbollar av laongstraeckta fibrer som foeljer med enluftstroem
ATA126298A (de)	2002-04-15	Verpuffungsklappe

Legal Events

Date	Code	Title	Description
2005-11-21	FC2A	Withdrawal, rejection or dismissal of laid open patent application