NO20001548D0 - Endotelinantagonist og en renin-angiotensinsystem inhibitor som et kombinert preparat - Google Patents

Endotelinantagonist og en renin-angiotensinsystem inhibitor som et kombinert preparat

Info

Publication number: NO20001548D0
Authority: NO; Norway
Prior art keywords: renin; combined preparation; angiotensin system; endothelin antagonist; system inhibitor
Prior art date: 1997-09-26

Application number

NO20001548A

Other languages

English (en)

Other versions

NO20001548L (no

NO324382B1 (no

Inventor

Klaus Muenter

Michael Kirchengast

Horst Korioth

Original Assignee

Knoll Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-09-26

Filing date

2000-03-24

Publication date

2000-03-24

1997-09-26 Priority claimed from DE19742717A external-priority patent/DE19742717A1/de

1997-09-30 Priority claimed from DE1997143141 external-priority patent/DE19743141A1/de

2000-03-24 Application filed by Knoll Ag filed Critical Knoll Ag

2000-03-24 Publication of NO20001548D0 publication Critical patent/NO20001548D0/no

2000-03-24 Publication of NO20001548L publication Critical patent/NO20001548L/no

2007-10-01 Publication of NO324382B1 publication Critical patent/NO324382B1/no

Links

239000002308 endothelin receptor antagonist Substances 0.000 title 1
239000003112 inhibitor Substances 0.000 title 1
230000036454 renin-angiotensin system Effects 0.000 title 1
102000002045 Endothelin Human genes 0.000 abstract 1
108050009340 Endothelin Proteins 0.000 abstract 1
229940078123 Ras inhibitor Drugs 0.000 abstract 1
239000005557 antagonist Substances 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
ZUBDGKVDJUIMQQ-UBFCDGJISA-N endothelin-1 Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(O)=O)NC(=O)[C@H]1NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@@H](CC=2C=CC(O)=CC=2)NC(=O)[C@H](C(C)C)NC(=O)[C@H]2CSSC[C@@H](C(N[C@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N2)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](N)CSSC1)C1=CNC=N1 ZUBDGKVDJUIMQQ-UBFCDGJISA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/556—Angiotensin converting enzyme inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Cardiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

NO20001548A 1997-09-26 2000-03-24 Kombinasjon av endotelinantagonist og en reninangiotensinsystem(RAS)-inhibitor, farmasoytisk preparat som omfatter kombinasjonen, samt fremstilling av preparatet og anvendelse av kombinasjonen. NO324382B1 (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE19742717A DE19742717A1 (de)	1997-09-26	1997-09-26	Pharmazeutische Kombinationspräparate
DE1997143141 DE19743141A1 (de)	1997-09-30	1997-09-30	Pharmazeutische Kombinationspräparate
PCT/EP1998/005773 WO1999016445A1 (de)	1997-09-26	1998-09-10	Endothelin antagonist und renin-angitensin systems hemmer als kombinationspräparate

Publications (3)

Publication Number	Publication Date
NO20001548D0 true NO20001548D0 (no)	2000-03-24
NO20001548L NO20001548L (no)	2000-03-24
NO324382B1 NO324382B1 (no)	2007-10-01

Family

ID=26040370

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20001548A NO324382B1 (no)	1997-09-26	2000-03-24	Kombinasjon av endotelinantagonist og en reninangiotensinsystem(RAS)-inhibitor, farmasoytisk preparat som omfatter kombinasjonen, samt fremstilling av preparatet og anvendelse av kombinasjonen.

Country Status (15)

Country	Link
US (1)	US6329384B1 (no)
EP (1)	EP1014989B1 (no)
JP (2)	JP4917707B2 (no)
KR (1)	KR100623121B1 (no)
CN (1)	CN1187050C (no)
AT (1)	ATE257706T1 (no)
AU (1)	AU750755B2 (no)
BR (1)	BR9812531A (no)
CA (1)	CA2304712C (no)
CZ (1)	CZ299741B6 (no)
DE (1)	DE59810600D1 (no)
ES (1)	ES2214734T3 (no)
HU (1)	HU226454B1 (no)
NO (1)	NO324382B1 (no)
WO (1)	WO1999016445A1 (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19533023B4 (de) *	1994-10-14	2007-05-16	Basf Ag	Neue Carbonsäurederivate, ihre Herstellung und Verwendung
US6329384B1 (en) *	1997-09-26	2001-12-11	Abbott Laboratories	Endothelin antagonist and renin-angiotensin system inhibitor as a combined preparation
JP2009256209A (ja) *	2006-02-17	2009-11-05	Gilead Colorado Inc	降圧療法
CA2642685A1 (en) *	2006-02-17	2007-08-30	Gilead Colorado, Inc.	Antihypertensive therapy
US20070196510A1 (en) *	2006-02-17	2007-08-23	Gerber Michael J	Method for treating resistant hypertension
EP2086518A2 (en) *	2006-11-09	2009-08-12	Gilead Colorado, Inc.	Darusentan oral dosage form
US20080139483A1 (en) *	2006-12-12	2008-06-12	Gorczynski Richard J	Drug combination for hypertensive disorders
EP2190433A2 (en)	2007-08-22	2010-06-02	Gilead Colorado, Inc.	Therapy for complications of diabetes
US20090076119A1 (en) *	2007-09-19	2009-03-19	Protia, Llc	Deuterium-enriched ramipril
WO2018002673A1 (en)	2016-07-01	2018-01-04	N4 Pharma Uk Limited	Novel formulations of angiotensin ii receptor antagonists

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT617001E (pt) *	1993-03-19	2000-06-30	Merck & Co Inc	Derivados do acido fenoxifenilacetico
ATE198551T1 (de)	1993-07-15	2001-01-15	Hoffmann La Roche	Pharmazeutische kombination, die einen hemmer des renin-angiotensin-systems und einen endothelin- antagonisten enthält
DE19533023B4 (de) *	1994-10-14	2007-05-16	Basf Ag	Neue Carbonsäurederivate, ihre Herstellung und Verwendung
EP2301562B1 (en) *	1994-12-12	2013-04-17	Omeros Corporation	Irrigation solution and method for inhibition of pain, inflammation and spasm
AU706940B2 (en) *	1995-01-27	1999-07-01	Rhone-Poulenc Rorer Limited	Substituted phenyl compounds as endothelin antagonists
DE19636046A1 (de) *	1996-09-05	1998-03-12	Basf Ag	Neue Carbonsäurederivate, ihre Herstellung und Verwendung als gemischte ET¶A¶/ET¶B¶-Rezeptorantagonisten
DE19652374A1 (de)	1996-12-04	1998-06-10	Schering Ag	Verwendung von Endothelin-Konjugaten in der Therapie, neue Endothelin-Konjugate, diese enthaltende Mittel, sowie Verfahren zu deren Herstellung
CN1247533A (zh)	1996-12-18	2000-03-15	Basf公司	杂环羧酸衍生物,它们的制备方法和它们作为内皮素(endothelin)受体拮抗剂的用途
US6329384B1 (en) *	1997-09-26	2001-12-11	Abbott Laboratories	Endothelin antagonist and renin-angiotensin system inhibitor as a combined preparation

1998
- 1998-09-10 US US09/508,993 patent/US6329384B1/en not_active Expired - Lifetime
- 1998-09-10 KR KR1020007003220A patent/KR100623121B1/ko not_active Expired - Fee Related
- 1998-09-10 CZ CZ20001107A patent/CZ299741B6/cs not_active IP Right Cessation
- 1998-09-10 EP EP98948954A patent/EP1014989B1/de not_active Expired - Lifetime
- 1998-09-10 JP JP2000513581A patent/JP4917707B2/ja not_active Expired - Fee Related
- 1998-09-10 AT AT98948954T patent/ATE257706T1/de not_active IP Right Cessation
- 1998-09-10 WO PCT/EP1998/005773 patent/WO1999016445A1/de not_active Ceased
- 1998-09-10 CN CNB988095459A patent/CN1187050C/zh not_active Expired - Fee Related
- 1998-09-10 CA CA002304712A patent/CA2304712C/en not_active Expired - Fee Related
- 1998-09-10 DE DE59810600T patent/DE59810600D1/de not_active Expired - Lifetime
- 1998-09-10 BR BR9812531-1A patent/BR9812531A/pt not_active Application Discontinuation
- 1998-09-10 HU HU0004298A patent/HU226454B1/hu not_active IP Right Cessation
- 1998-09-10 AU AU95395/98A patent/AU750755B2/en not_active Ceased
- 1998-09-10 ES ES98948954T patent/ES2214734T3/es not_active Expired - Lifetime
2000
- 2000-03-24 NO NO20001548A patent/NO324382B1/no not_active IP Right Cessation
2011
- 2011-09-27 JP JP2011210241A patent/JP2012046531A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
JP2001517704A (ja)	2001-10-09
AU9539598A (en)	1999-04-23
JP4917707B2 (ja)	2012-04-18
US6329384B1 (en)	2001-12-11
CN1187050C (zh)	2005-02-02
HUP0004298A3 (en)	2002-06-28
ES2214734T3 (es)	2004-09-16
CZ20001107A3 (cs)	2000-08-16
EP1014989A1 (de)	2000-07-05
CZ299741B6 (cs)	2008-11-05
WO1999016445A1 (de)	1999-04-08
ATE257706T1 (de)	2004-01-15
KR100623121B1 (ko)	2006-09-12
DE59810600D1 (de)	2004-02-19
CA2304712C (en)	2008-04-29
AU750755B2 (en)	2002-07-25
HU226454B1 (en)	2008-12-29
CN1271283A (zh)	2000-10-25
JP2012046531A (ja)	2012-03-08
NO20001548L (no)	2000-03-24
NO324382B1 (no)	2007-10-01
BR9812531A (pt)	2000-07-25
KR20010030713A (ko)	2001-04-16
CA2304712A1 (en)	1999-04-08
HUP0004298A2 (hu)	2001-11-28
EP1014989B1 (de)	2004-01-14

Publication	Publication Date	Title
FI973360L (fi)	1997-08-15	Uusia dipeptidisiä amidiineja trombiininestäjiksi
NO975244D0 (no)	1997-11-14	5-ring-heterocykluser som inhibitorer av leukocyttadhesjon og VLA-4-antagonister
TR199800759T2 (xx)	2001-01-22	Protein Kinaz C �nhibit�r�.
NO942650L (no)	1995-01-16	Farmasöytisk kombinasjonspreparat
DK0939632T3 (da)	2006-01-30	Non-peptidyl vasopressin V1a antagonister
DK1498124T3 (da)	2007-11-05	Anvendelse af inhibitorer i renin-angiotensinsystemet
ATE203519T1 (de)	2001-08-15	Chinolinderivate als antimalariamittel
NO20001548L (no)	2000-03-24	Endotelinantagonist og en renin-angiotensinsystem inhibitor som et kombinert preparat
ATE266420T1 (de)	2004-05-15	Kombinationspräparat, das selektive nmda nr2b- antagonisten und cox-2 inhibitoren enthält
SE9601556D0 (sv)	1996-04-24	New pharmaceutical formulation of a thrombin inhibitor for parenteral use
ATE359793T1 (de)	2007-05-15	2-methyl-thieno-benzodiazepin formulierung
BR9809848A (pt)	2000-06-27	Composição
ATE234359T1 (de)	2003-03-15	Fusionsproteine bestehend aus gewebefaktor- kunitzdomäne als inhibitoren des faktors viia
NO20014855L (no)	2001-12-06	N-(2-fenyl-4-aminobutyl)-1-naftamider som neurokinin-1- reseptorantagonister
DE69625230D1 (de)	2003-01-16	Thrombininhibitoren
ATE239479T1 (de)	2003-05-15	Endothelin antagonist und betarezeptorenblocker als kombinationspräparate
DK0910379T3 (da)	2003-08-11	Plaster til transdermal påføring af pergolid
BR0110902A (pt)	2003-12-30	Inibidores de mmp-9/mmp-2
UY26893A1 (es)	2002-03-22	Combinación farmacéutica de antagonistas de la angiotensina ii e inhibidores de la enzima de conversión de la angiotensina i
WO2002016432A3 (en)	2003-09-04	Two receptors of meiosis activating sterols designated sam1a and sam1b
TR199800488T1 (xx)	1998-05-21	Diskinezi i�in 5-HT3 resept�r antagonistleri.
SE9100950L (sv)	1992-10-03	Vvs-armatur foer tvaettstaell

Legal Events

Date	Code	Title	Description
2014-06-02	CHAD	Change of the owner's name or address (par. 44 patent law, par. patentforskriften)	Owner name: ABBVIE DEUTSCHLAND GMBH & CO AG, DE
2015-04-27	MM1K	Lapsed by not paying the annual fees