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NO174963C - Analogifremgangsmåte for fremstilling av terapeutisk aktive 8-fluorantracyklinglucosider - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive 8-fluorantracyklinglucosider

Info

Publication number
NO174963C
NO174963C NO911798A NO911798A NO174963C NO 174963 C NO174963 C NO 174963C NO 911798 A NO911798 A NO 911798A NO 911798 A NO911798 A NO 911798A NO 174963 C NO174963 C NO 174963C
Authority
NO
Norway
Prior art keywords
preparation
fluoroanthracycling
glucosides
therapeutically active
analogous process
Prior art date
Application number
NO911798A
Other languages
English (en)
Other versions
NO911798L (no
NO174963B (no
NO911798D0 (no
Inventor
Fabio Animati
Paolo Lombardi
Federico Arcamone
Original Assignee
Menarini Farma Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Farma Ind filed Critical Menarini Farma Ind
Publication of NO911798D0 publication Critical patent/NO911798D0/no
Publication of NO911798L publication Critical patent/NO911798L/no
Publication of NO174963B publication Critical patent/NO174963B/no
Publication of NO174963C publication Critical patent/NO174963C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/244—Anthraquinone radicals, e.g. sennosides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/14—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrane Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NO911798A 1990-05-14 1991-05-08 Analogifremgangsmåte for fremstilling av terapeutisk aktive 8-fluorantracyklinglucosider NO174963C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20300A IT1241927B (it) 1990-05-14 1990-05-14 3'-deamino-4'-deossi-4'-amino-8-fluoroantra- cicline processi per la loro preparazione e composizioni farmaceutiche che le contengono

Publications (4)

Publication Number Publication Date
NO911798D0 NO911798D0 (no) 1991-05-08
NO911798L NO911798L (no) 1991-11-15
NO174963B NO174963B (no) 1994-05-02
NO174963C true NO174963C (no) 1994-08-10

Family

ID=11165542

Family Applications (1)

Application Number Title Priority Date Filing Date
NO911798A NO174963C (no) 1990-05-14 1991-05-08 Analogifremgangsmåte for fremstilling av terapeutisk aktive 8-fluorantracyklinglucosider

Country Status (30)

Country Link
US (1) US5807835A (no)
EP (1) EP0457215B1 (no)
JP (1) JPH04226972A (no)
KR (1) KR910020025A (no)
CN (1) CN1031192C (no)
AT (1) ATE133177T1 (no)
AU (1) AU638574B2 (no)
BR (1) BR9101973A (no)
CA (1) CA2042463A1 (no)
CS (1) CS135891A3 (no)
DE (1) DE69116423T2 (no)
DK (1) DK0457215T3 (no)
ES (1) ES2084724T3 (no)
FI (1) FI912269A (no)
GR (1) GR3018716T3 (no)
HU (1) HU209458B (no)
IE (1) IE911634A1 (no)
IL (1) IL98117A0 (no)
IT (1) IT1241927B (no)
MA (1) MA22153A1 (no)
MX (1) MX25747A (no)
NO (1) NO174963C (no)
PL (1) PL290236A1 (no)
PT (1) PT97663B (no)
RO (1) RO108792B1 (no)
RU (1) RU2095365C1 (no)
TN (1) TNSN91036A1 (no)
TW (1) TW228524B (no)
YU (1) YU83691A (no)
ZA (1) ZA913644B (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1262565B (it) * 1993-09-30 1996-07-04 Menarini Farma Ind Disaccaridi di antracicline, loro processi di preparazione e composizioni farmaceutiche che li contengono.
IT1271689B (it) * 1994-08-04 1997-06-04 Menarini Farma Ind 8-fluoro-antracicline, loro processi di preparazione e composizioni farmaceutiche che le contengono
US8357785B2 (en) * 2008-01-08 2013-01-22 Solux Corporation Method of aralkylation of 4′-hydroxyl group of anthracylins
CN104098628B (zh) * 2014-07-31 2017-07-18 大连大学 一类n‑三氟乙酰柔红霉素的硒代衍生物，其制备方法及应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4663445A (en) * 1985-03-20 1987-05-05 The Ohio State Research Foundation 1-fluoro, 4-fluoro, and 1,4-difluoro-2'-halo anthracycline antibiotics
GB8803076D0 (en) * 1988-02-10 1988-03-09 Erba Carlo Spa 3'-deamino-4'-deoxy-4'-amino anthracyclines
GB8902709D0 (en) * 1989-02-07 1989-03-30 Erba Carlo Spa New 4'-epi-4'-amino anthracyclines

Also Published As

Publication number Publication date
RO108792B1 (ro) 1994-08-30
US5807835A (en) 1998-09-15
RU2095365C1 (ru) 1997-11-10
DE69116423T2 (de) 1996-06-27
PL290236A1 (en) 1992-07-27
HU209458B (en) 1994-06-28
CN1031192C (zh) 1996-03-06
TW228524B (no) 1994-08-21
EP0457215A1 (en) 1991-11-21
IL98117A0 (en) 1992-06-21
TNSN91036A1 (fr) 1992-10-25
IT1241927B (it) 1994-02-01
DK0457215T3 (da) 1996-06-10
IT9020300A0 (it) 1990-05-14
MA22153A1 (fr) 1991-12-31
KR910020025A (ko) 1991-12-19
NO911798L (no) 1991-11-15
CN1056500A (zh) 1991-11-27
CS135891A3 (en) 1992-02-19
AU7649391A (en) 1991-11-14
JPH04226972A (ja) 1992-08-17
NO174963B (no) 1994-05-02
MX25747A (es) 1994-03-31
CA2042463A1 (en) 1991-11-15
IE911634A1 (en) 1991-11-20
PT97663B (pt) 1998-09-30
BR9101973A (pt) 1991-12-24
NO911798D0 (no) 1991-05-08
HUT57227A (en) 1991-11-28
ZA913644B (en) 1992-02-26
ATE133177T1 (de) 1996-02-15
DE69116423D1 (de) 1996-02-29
IT9020300A1 (it) 1991-11-14
EP0457215B1 (en) 1996-01-17
PT97663A (pt) 1992-03-31
GR3018716T3 (en) 1996-04-30
FI912269A0 (fi) 1991-05-10
ES2084724T3 (es) 1996-05-16
YU83691A (sh) 1994-01-20
AU638574B2 (en) 1993-07-01
FI912269A (fi) 1991-11-15

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