[go: up one dir, main page]

NO166707C - Direkte komprimerbar, granulaer mannitol og fremstilling derav. - Google Patents

Direkte komprimerbar, granulaer mannitol og fremstilling derav.

Info

Publication number
NO166707C
NO166707C NO853918A NO853918A NO166707C NO 166707 C NO166707 C NO 166707C NO 853918 A NO853918 A NO 853918A NO 853918 A NO853918 A NO 853918A NO 166707 C NO166707 C NO 166707C
Authority
NO
Norway
Prior art keywords
mannitol
raw material
heating zone
compressable
direct
Prior art date
Application number
NO853918A
Other languages
English (en)
Norwegian (no)
Other versions
NO853918L (no
NO166707B (no
Inventor
Michel Serpelloni
Patrick Lemay
Original Assignee
Roquette Freres
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roquette Freres filed Critical Roquette Freres
Publication of NO853918L publication Critical patent/NO853918L/no
Publication of NO166707B publication Critical patent/NO166707B/no
Publication of NO166707C publication Critical patent/NO166707C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/18—Polyhydroxylic acyclic alcohols
    • C07C31/26—Hexahydroxylic alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/20—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by expressing the material, e.g. through sieves and fragmenting the extruded length
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/74—Separation; Purification; Use of additives, e.g. for stabilisation
    • C07C29/76—Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO853918A 1984-10-03 1985-10-03 Direkte komprimerbar, granulaer mannitol og fremstilling derav. NO166707C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8415212A FR2571046B1 (fr) 1984-10-03 1984-10-03 Procede de preparation de mannitol granulaire directement compressible

Publications (3)

Publication Number Publication Date
NO853918L NO853918L (no) 1986-04-04
NO166707B NO166707B (no) 1991-05-21
NO166707C true NO166707C (no) 1991-08-28

Family

ID=9308323

Family Applications (1)

Application Number Title Priority Date Filing Date
NO853918A NO166707C (no) 1984-10-03 1985-10-03 Direkte komprimerbar, granulaer mannitol og fremstilling derav.

Country Status (16)

Country Link
US (1) US5160680A (es)
EP (1) EP0177428B1 (es)
JP (1) JPH0643352B2 (es)
KR (1) KR930007408B1 (es)
CN (1) CN1005963B (es)
AT (1) ATE36466T1 (es)
CA (1) CA1272216A (es)
DE (1) DE3564380D1 (es)
DK (1) DK173282B1 (es)
ES (1) ES8700219A1 (es)
FI (1) FI85367C (es)
FR (1) FR2571046B1 (es)
GR (1) GR852391B (es)
IE (1) IE58890B1 (es)
NO (1) NO166707C (es)
PT (1) PT81251B (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3522359A1 (de) * 1985-06-22 1987-01-02 Basf Ag Verfahren zum konfektionieren von kristallinen, organischen materialien
BE1002635A6 (nl) * 1988-12-09 1991-04-16 Amylum Nv Werkwijze voor het vervaardigen van een mengsel van zetmeel en polyvinylalcohol en aldus vervaardigd mengsel.
ES2145063T3 (es) * 1992-10-14 2000-07-01 Nippon Shinyaku Co Ltd Procedimiento de dislocacion del estado cristalino.
US5811547A (en) * 1992-10-14 1998-09-22 Nippon Shinyaju Co., Ltd. Method for inducing crystalline state transition in medicinal substance
FR2710637B1 (fr) * 1993-09-28 1995-12-08 Roquette Freres Mannitol pulvérulent de friabilité modérée et son procédé de préparation.
DE19541242A1 (de) 1995-11-06 1997-05-07 Hoechst Ag Lagerstabile Kunststoffadditive
NZ332313A (en) 1996-04-16 2000-02-28 Bayer Ag D-mannitol and its preparation as a powder of not more than 1 square meter per gram
US6235947B1 (en) * 1997-04-14 2001-05-22 Takeda Chemical Industries, Ltd. D-mannitol and its preparation
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
WO2000024380A1 (en) * 1998-10-27 2000-05-04 Fuisz Technologies Ltd. Microparticles containing peg and/or peg glyceryl esters
US7815937B2 (en) * 1998-10-27 2010-10-19 Biovail Laboratories International Srl Quick dissolve compositions and tablets based thereon
CA2342121C (fr) * 2000-03-29 2010-05-25 Roquette Freres Mannitol pulverulent et son procede de preparation
WO2002007957A2 (en) * 2000-07-24 2002-01-31 Boehringer Ingelheim Pharmaceuticals, Inc. Apparatus and method for predicting the suitability of a substance for dry granulation by roller compaction using small sample sizes
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
DE10161402A1 (de) * 2001-12-13 2003-06-18 Merck Patent Gmbh Verfahren zur Herstellung von direkt tablettierbarem beta-Mannit
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
US8545881B2 (en) 2004-04-19 2013-10-01 Eurand Pharmaceuticals, Ltd. Orally disintegrating tablets and methods of manufacture
CA2568717C (en) * 2004-06-17 2013-12-10 Cargill Incorporated Steam agglomeration of polyols
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
EP2417969A1 (en) 2004-10-21 2012-02-15 Aptalis Pharmatech, Inc. Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US20060105038A1 (en) * 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
US20100152299A1 (en) * 2005-05-10 2010-06-17 Madhav Vasanthavada Process for making compositions with poorly compressible therapeutic compounds
CN101166517B (zh) * 2005-05-10 2012-01-04 诺瓦提斯公司 制备含有可压性差的治疗性化合物的组合物的挤压方法
CN100413834C (zh) * 2006-07-11 2008-08-27 广西南宁化学制药有限责任公司 一种可压缩颗粒甘露醇的制备方法
EP2264042B1 (en) 2007-07-27 2012-07-18 Cargill, Incorporated Micronization of polyols
TWI471146B (zh) 2009-12-02 2015-02-01 Aptalis Pharma Ltd 菲索特芬那定（ｆｅｘｏｆｅｎａｄｉｎｅ）微膠囊及包含其之組合物
CN103196284A (zh) * 2013-04-08 2013-07-10 马锡林 制粒式单锥干燥器
FR3038836B1 (fr) 2015-07-17 2017-07-14 Roquette Freres Granules de mannitol pour compression directe
CN110787722A (zh) * 2019-12-01 2020-02-14 浙江华康药业股份有限公司 一种结晶甘露醇干法造粒装置及工艺

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2951263A (en) * 1957-10-30 1960-09-06 Heyden Newport Chemical Corp Treatment of polyhydric alcohols
US3341415A (en) * 1964-02-12 1967-09-12 Warner Lambert Pharmaceutical Pharmaceutical tablet excipients of solid particles of a binary solid solution of mannitol with a sugar
US3966857A (en) * 1969-12-31 1976-06-29 Congoleum Industries, Inc. Lubrication of extruded materials
US4133857A (en) * 1975-09-16 1979-01-09 Chisso Corporation Method for producing a granular sorbic acid
JPS5220444A (en) * 1976-06-16 1977-02-16 Matsushita Electric Ind Co Ltd Extinguisher of liquid fuel combustor
JPS5365806A (en) * 1976-11-19 1978-06-12 Nippon Shiryo Kogyo Kk Method of making granular powder of crystalline sugar alcohol
US4302413A (en) * 1978-11-16 1981-11-24 Rogers Corporation Process for preparing extrudable polyimide granules
FR2451357A1 (fr) * 1979-03-16 1980-10-10 Roquette Freres Procede pour la mise sous forme comprimee du sorbitol et produit resultant
GB2054599B (en) * 1979-06-08 1983-03-16 Nat Res Dev Tableting of powder mixtures
DE3049196A1 (de) * 1980-12-24 1982-07-29 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von granulaten aus organischen in form einer schmelze vorliegenden stoffen
DE3245170A1 (de) * 1982-12-07 1984-06-07 Merck Patent Gmbh, 6100 Darmstadt Verbesserter sorbit, verfahren zur herstellung und verwendung
FR2588005B1 (fr) * 1985-10-02 1987-12-11 Roquette Freres Maltitol poudre directement compressible et son procede de preparation

Also Published As

Publication number Publication date
PT81251B (pt) 1987-10-20
IE852425L (en) 1986-04-03
CN1005963B (zh) 1989-12-06
EP0177428A1 (fr) 1986-04-09
JPS61178943A (ja) 1986-08-11
IE58890B1 (en) 1993-12-01
GR852391B (es) 1985-12-23
FI853843A0 (fi) 1985-10-03
FI85367C (fi) 1992-04-10
ES8700219A1 (es) 1986-10-01
ES547529A0 (es) 1986-10-01
NO853918L (no) 1986-04-04
NO166707B (no) 1991-05-21
DK173282B1 (da) 2000-06-05
US5160680A (en) 1992-11-03
EP0177428B1 (fr) 1988-08-17
FI85367B (fi) 1991-12-31
FI853843L (fi) 1986-04-04
FR2571046A1 (fr) 1986-04-04
CA1272216A (en) 1990-07-31
JPH0643352B2 (ja) 1994-06-08
FR2571046B1 (fr) 1987-10-16
DE3564380D1 (en) 1988-09-22
KR860002979A (ko) 1986-05-19
CN85108629A (zh) 1986-07-23
ATE36466T1 (de) 1988-09-15
DK450585D0 (da) 1985-10-03
KR930007408B1 (ko) 1993-08-10
DK450585A (da) 1986-04-04
PT81251A (fr) 1985-11-01

Similar Documents

Publication Publication Date Title
NO166707C (no) Direkte komprimerbar, granulaer mannitol og fremstilling derav.
DE3276321D1 (en) Continuous process for producing oxymethylene polymers
DE3579849D1 (de) Eprom mit selbstjustierter geteilter steuerelektrode und verfahren zur herstellung.
EP0216702A3 (en) Method and plant for tartars separation
OA06752A (fr) Procédé et appareil pour extrusion continue avec entraînement de la matière par action de frottement.
DE3586548D1 (de) Steuersystem des erzeugungsprozesses.
FR2531870B1 (fr) Mousqueton, notamment pour l'alpinisme, et son procede de fabrication
HUT45961A (en) Process for producing new acids and tetrazols of selective leukotriene-antagonistic activity
ES508938A0 (es) "procedimiento para suministrar fibras para la fabricacion de hilados de fantasia y dispositivo para su realizacion".
IT8520330A0 (it) Procedimento per l'adduzione dell'aria di raffreddamento in pozzi per il raffreddamento e la solidificazione di fili filati per fusione e simili, nonche' pozzo di raffreddamento di fili a tale scopo.
IL44773A (en) Method of regulating the growth of plant life by the use of 2,3-dihydro-1,4-dithiin 1,1,4,4-tetroxides and certain 2,3-dihydro-1,4-dithiin 1,1,4,4-tetroxides
DE3272453D1 (en) Process for producing pitch for use as raw material for carbon fibers and carbon fibers produced from the pitch
GB2108490B (en) Process for producing esters of 3,5-dibromo-4-hydroxybenzonitrile
PT74906B (en) Method for producing spinnable polyamides of the so-called nylon
YU61982A (en) Process for producing intermediates useful in the production of 1,1-dioxo-penicillanoyloxy-methyl-6-(2-amino-2-phenylacetamido0penicillanate
DE3065302D1 (en) Method of controlling the production rate of an extruder
FR2455437A3 (fr) Procede et dispositif pour fabriquer par extrusion du chewing-gum fourre
FR2574700B1 (fr) Materiau composite constitue d'une gaine thermoplastique continue et d'une ame sensible a la temperature de fusion de la gaine. son procede de fabrication
FI102537B (fi) Dehalogenointimenetelmä 3-aroyyli-2-oksindoli-1-karboksiamidien valmis tamiseksi
FR2531965B1 (fr) Procede de production de polyethylene chlorosulfone avec reglage de la quantite de soufre ajoutee
KR870700627A (ko) 세팔로스포린 유도체의 신규 제조방법
SU668893A2 (ru) Устройство дл выт гивани вниз листового стекла
DE3461033D1 (en) Method of controlled, uniform doping of floating zone silicon
FR2283127A1 (fr) Procede de production selective de composes 4,4'-mono-thiodiphenoliques avec des rendements eleves
JPS5316948A (en) Ice production machine thermally controlling the supply of water

Legal Events

Date Code Title Description
MK1K Patent expired