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NO152047C - Analogifremgangsmaate for fremstilling av terapeutisk virksom 5-(paradeuterofenyl)-5-fenylhydantoin - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk virksom 5-(paradeuterofenyl)-5-fenylhydantoin

Info

Publication number
NO152047C
NO152047C NO800447A NO800447A NO152047C NO 152047 C NO152047 C NO 152047C NO 800447 A NO800447 A NO 800447A NO 800447 A NO800447 A NO 800447A NO 152047 C NO152047 C NO 152047C
Authority
NO
Norway
Prior art keywords
paradeuterophenyl
preparation
therapeutic activity
deuterated
linear
Prior art date
Application number
NO800447A
Other languages
English (en)
Norwegian (no)
Other versions
NO152047B (no
NO800447L (no
Inventor
Pierre Dumont
Jacques Poupaert
Original Assignee
Wallone Region
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wallone Region filed Critical Wallone Region
Publication of NO800447L publication Critical patent/NO800447L/no
Publication of NO152047B publication Critical patent/NO152047B/no
Publication of NO152047C publication Critical patent/NO152047C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
NO800447A 1979-02-20 1980-02-19 Analogifremgangsmaate for fremstilling av terapeutisk virksom 5-(paradeuterofenyl)-5-fenylhydantoin NO152047C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7904209A FR2449448B1 (fr) 1979-02-20 1979-02-20 Composition pharmaceutique comprenant un derive de phenylhydantoine, derives mis en oeuvre et leur preparation

Publications (3)

Publication Number Publication Date
NO800447L NO800447L (no) 1980-08-21
NO152047B NO152047B (no) 1985-04-15
NO152047C true NO152047C (no) 1985-07-24

Family

ID=9222166

Family Applications (1)

Application Number Title Priority Date Filing Date
NO800447A NO152047C (no) 1979-02-20 1980-02-19 Analogifremgangsmaate for fremstilling av terapeutisk virksom 5-(paradeuterofenyl)-5-fenylhydantoin

Country Status (11)

Country Link
US (1) US4304782A (da)
EP (1) EP0015038B1 (da)
JP (1) JPS55133362A (da)
AT (1) ATE10804T1 (da)
CA (1) CA1139672A (da)
DE (1) DE3069813D1 (da)
DK (1) DK71780A (da)
ES (1) ES488788A0 (da)
FI (1) FI71556C (da)
FR (1) FR2449448B1 (da)
NO (1) NO152047C (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07106837B2 (ja) * 1989-01-31 1995-11-15 シャープ株式会社 シート状体の循環式供給装置
USRE35956E (en) * 1991-01-09 1998-11-10 Roussel Uclaf Phenylimidazolidines having antiandrogenic activity
US5411981A (en) * 1991-01-09 1995-05-02 Roussel Uclaf Phenylimidazolidines having antiandrogenic activity
JPH04297461A (ja) * 1991-03-27 1992-10-21 Otsuka Pharmaceut Factory Inc ２−チオヒダントイン誘導体
US6334997B1 (en) 1994-03-25 2002-01-01 Isotechnika, Inc. Method of using deuterated calcium channel blockers
EP0751926B1 (en) * 1994-03-25 2007-09-12 Isotechnika,Inc. Enhancement of the efficacy of drugs by deuteration
WO1999048876A1 (en) * 1998-03-20 1999-09-30 Warner-Lambert Company Crystalline sodium phenytoin monohydrate
AU757290B2 (en) * 1998-03-25 2003-02-13 Bristol-Myers Squibb Company Imidazolone anorectic agents: II. phenyl derivatives
DE10214228A1 (de) * 2002-03-22 2003-10-02 Bdd Group Holding Ag Zug Deuterierte substitutierte Indole sowie diese Verbindungen enthaltende Arzneimittel
EP2299266A1 (en) * 2003-12-19 2011-03-23 The Regents of the University of California Methods and materials for assessing prostate cancer therapies
AU2005232526B2 (en) * 2004-02-24 2011-06-23 The Regents Of The University Of California Methods and materials for assessing prostate cancer therapies and compounds
US7709517B2 (en) * 2005-05-13 2010-05-04 The Regents Of The University Of California Diarylhydantoin compounds
ES2588606T3 (es) 2006-03-27 2016-11-03 The Regents Of The University Of California Modulador del receptor de andrógenos para el tratamiento del cáncer de próstata y enfermedades asociadas con el receptor de andrógenos
KR20160027254A (ko) 2006-03-29 2016-03-09 더 리전트 오브 더 유니버시티 오브 캘리포니아 디아릴티오히단토인 화합물
US8680291B2 (en) 2007-10-26 2014-03-25 The Regents Of The University Of California Diarylhydantoin compounds
EA023981B1 (ru) 2010-02-16 2016-08-31 Арагон Фармасьютикалс, Инк. Модуляторы рецептора андрогенов и их применение
EA037806B1 (ru) 2012-09-26 2021-05-24 Арагон Фармасьютикалз, Инк. Способ лечения неметастатического кастрационно-резистентного рака простаты
JOP20200097A1 (ar) 2013-01-15 2017-06-16 Aragon Pharmaceuticals Inc معدل مستقبل أندروجين واستخداماته
TWI726969B (zh) 2016-01-11 2021-05-11 比利時商健生藥品公司 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
WO2019078920A1 (en) 2017-10-16 2019-04-25 Aragon Pharmaceuticals, Inc. ANTI-ANDROGENS FOR THE TREATMENT OF NON-METASTATIC RESISTANT PROSTATE CANCER

Also Published As

Publication number Publication date
FI71556C (fi) 1987-01-19
FR2449448A1 (fr) 1980-09-19
FI71556B (fi) 1986-10-10
ATE10804T1 (de) 1985-01-15
CA1139672A (en) 1983-01-18
EP0015038A1 (fr) 1980-09-03
US4304782A (en) 1981-12-08
NO152047B (no) 1985-04-15
DK71780A (da) 1980-08-21
JPS55133362A (en) 1980-10-17
FI800502A (fi) 1980-08-21
EP0015038B1 (fr) 1984-12-19
ES8200011A1 (es) 1981-10-16
DE3069813D1 (en) 1985-01-31
NO800447L (no) 1980-08-21
ES488788A0 (es) 1981-10-16
FR2449448B1 (fr) 1983-05-27

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