NL7612198A - 2,6-DIMETHYL-3-METHOXYCARBONYL-4- (2'-NITROPHENYL) -1,4-DIHYDROPYRIDINE-5-CARBONIC ACID ISOBUTYL ESTER METHODS FOR PREPARING IT AND ITS USE AS A CORONAIR THERAPY. - Google Patents

2,6-DIMETHYL-3-METHOXYCARBONYL-4- (2'-NITROPHENYL) -1,4-DIHYDROPYRIDINE-5-CARBONIC ACID ISOBUTYL ESTER METHODS FOR PREPARING IT AND ITS USE AS A CORONAIR THERAPY.

Info

Publication number: NL7612198A
Authority: NL; Netherlands
Prior art keywords: coronair; dihydropyridine; methoxycarbonyl; nitrophenyl; therapy
Prior art date: 1975-11-05

Application number

NL7612198A

Other languages

Dutch (nl)

Other versions

NL175915C (en

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-11-05

Filing date

1976-11-03

Publication date

1977-05-09

1976-11-03 Application filed by Bayer Ag filed Critical Bayer Ag

1977-05-09 Publication of NL7612198A publication Critical patent/NL7612198A/en

1985-01-16 Application granted granted Critical

1985-01-16 Publication of NL175915C publication Critical patent/NL175915C/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Heart & Thoracic Surgery (AREA)
General Health & Medical Sciences (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

NLAANVRAGE7612198,A 1975-11-05 1976-11-03 METHOD FOR PREPARING CORONARY ACTIVE PREPARATIONS, AND METHOD FOR PREPARING A 2,6-DIMETHYL-3-METHOXYCARBONYL-4- (2'-NITROPHYYLYDYLYDYLYDYDYLYDYDYDYYDYYLYYDYYDYLYLUS am]]]] -PREYPHYLYPHYLYPHYLYPHYLENE -ESTER. NL175915C (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE2549568A DE2549568C3 (en)	1975-11-05	1975-11-05	2,6-Dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl) -1,4-dihydropyridine-5-carboxylic acid isobutyl ester, several processes for its preparation and pharmaceuticals containing it

Publications (2)

Publication Number	Publication Date
NL7612198A true NL7612198A (en)	1977-05-09
NL175915C NL175915C (en)	1985-01-16

Family

ID=5960951

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NLAANVRAGE7612198,A NL175915C (en)	1975-11-05	1976-11-03	METHOD FOR PREPARING CORONARY ACTIVE PREPARATIONS, AND METHOD FOR PREPARING A 2,6-DIMETHYL-3-METHOXYCARBONYL-4- (2'-NITROPHYYLYDYLYDYLYDYDYLYDYDYDYYDYYLYYDYYDYLYLUS am]]]] -PREYPHYLYPHYLYPHYLYPHYLENE -ESTER.
NL930035C NL930035I2 (en)	1975-11-05	1993-05-24	Process for the preparation of coronary active preparations, and process for the preparation of a 2,6-dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl) -1,4-dihydropyridine-5-carboxylic acid to be used in such preparations -ester.

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
NL930035C NL930035I2 (en)	1975-11-05	1993-05-24	Process for the preparation of coronary active preparations, and process for the preparation of a 2,6-dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl) -1,4-dihydropyridine-5-carboxylic acid to be used in such preparations -ester.

Country Status (27)

Country	Link
JP (1)	JPS5259161A (en)
AT (1)	AT352129B (en)
AU (1)	AU498964B2 (en)
BE (1)	BE847968A (en)
BG (6)	BG24805A3 (en)
CA (1)	CA1085406A (en)
CH (2)	CH623038A5 (en)
CS (1)	CS200499B2 (en)
DE (1)	DE2549568C3 (en)
DK (1)	DK146762C (en)
ES (2)	ES452986A1 (en)
FI (1)	FI60704C (en)
FR (1)	FR2330395A1 (en)
GB (1)	GB1516793A (en)
GR (1)	GR61241B (en)
HK (1)	HK12681A (en)
IE (1)	IE43984B1 (en)
IL (1)	IL50817A (en)
LU (2)	LU76133A1 (en)
NL (2)	NL175915C (en)
NO (1)	NO145574C (en)
NZ (1)	NZ182502A (en)
PL (2)	PL105940B1 (en)
PT (1)	PT65797B (en)
RO (1)	RO70295A (en)
SE (1)	SE423542B (en)
ZA (1)	ZA766622B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4146630A (en) *	1976-11-12	1979-03-27	Boehringer Mannheim Gmbh	Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers
JPS55301A (en) *	1978-02-14	1980-01-05	Yamanouchi Pharmaceut Co Ltd	1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
DE3212736A1 (en) *	1982-04-06	1983-10-13	Bayer Ag, 5090 Leverkusen	USE OF DIHYDROPYRIDINES IN MEDICINAL PRODUCTS WITH SALIDIURETIC EFFECT
DE3222367A1 (en) *	1982-06-15	1983-12-15	Bayer Ag, 5090 Leverkusen	Use of 1,4-dihydropyridines in antiarteriosclerotics and preparation thereof
JPS5982192U (en) *	1982-11-27	1984-06-02	エムケ−精工株式会社	door
DE3312216A1 (en) *	1983-04-05	1984-10-11	Bayer Ag, 5090 Leverkusen	METHOD FOR PRODUCING SYMMETRIC 1,4-DIHYDROPYRIDINE CARBONIC ACID ESTERS
DE3312283A1 (en) *	1983-04-05	1984-10-18	Bayer Ag, 5090 Leverkusen	METHOD FOR PRODUCING UNBALANCED 1,4-DIHYDROPYRIDINE CARBONIC ACID ESTERS
US4794111A (en) *	1984-05-23	1988-12-27	Bayer Aktiengesellschaft	Dihydropyridine preparations containing β-blockers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2117571C3 (en) *	1971-04-10	1979-10-11	Bayer Ag, 5090 Leverkusen	Asymmetrical 1,4-dihydropyridine-33-dicarboxylic acid esters, process for their preparation and their use as pharmaceuticals

1975
- 1975-11-05 DE DE2549568A patent/DE2549568C3/en not_active Expired
1976
- 1976-10-22 NO NO763608A patent/NO145574C/en unknown
- 1976-10-29 JP JP51129540A patent/JPS5259161A/en active Granted
- 1976-11-01 BG BG035345A patent/BG24805A3/en unknown
- 1976-11-01 BG BG035343A patent/BG24803A3/en unknown
- 1976-11-01 BG BG034575A patent/BG24668A3/en unknown
- 1976-11-01 BG BG035341A patent/BG25078A3/en unknown
- 1976-11-01 BG BG035344A patent/BG24804A3/en unknown
- 1976-11-01 BG BG035342A patent/BG25079A3/en unknown
- 1976-11-02 IL IL50817A patent/IL50817A/en unknown
- 1976-11-02 GB GB45501/76A patent/GB1516793A/en not_active Expired
- 1976-11-02 RO RO7688294A patent/RO70295A/en unknown
- 1976-11-02 CH CH1381976A patent/CH623038A5/en not_active IP Right Cessation
- 1976-11-02 CS CS767068A patent/CS200499B2/en unknown
- 1976-11-02 NZ NZ182502A patent/NZ182502A/en unknown
- 1976-11-03 AT AT814276A patent/AT352129B/en not_active IP Right Cessation
- 1976-11-03 PL PL1976201800A patent/PL105940B1/en unknown
- 1976-11-03 FI FI763160A patent/FI60704C/en not_active IP Right Cessation
- 1976-11-03 NL NLAANVRAGE7612198,A patent/NL175915C/en not_active IP Right Cessation
- 1976-11-03 PL PL1976193438A patent/PL106084B1/en unknown
- 1976-11-04 GR GR52093A patent/GR61241B/en unknown
- 1976-11-04 IE IE2458/76A patent/IE43984B1/en not_active IP Right Cessation
- 1976-11-04 ZA ZA766622A patent/ZA766622B/en unknown
- 1976-11-04 SE SE7612308A patent/SE423542B/en not_active IP Right Cessation
- 1976-11-04 ES ES452986A patent/ES452986A1/en not_active Expired
- 1976-11-04 LU LU76133A patent/LU76133A1/xx active Protection Beyond IP Right Term
- 1976-11-04 LU LU88275C patent/LU88275I2/xx unknown
- 1976-11-04 PT PT65797A patent/PT65797B/en unknown
- 1976-11-04 BE BE172063A patent/BE847968A/en not_active IP Right Cessation
- 1976-11-04 CA CA264,921A patent/CA1085406A/en not_active Expired
- 1976-11-04 DK DK498476A patent/DK146762C/en not_active IP Right Cessation
- 1976-11-05 AU AU19358/76A patent/AU498964B2/en not_active Expired
- 1976-11-05 FR FR7633488A patent/FR2330395A1/en active Granted
1977
- 1977-10-13 ES ES463166A patent/ES463166A1/en not_active Expired
1980
- 1980-07-23 CH CH567880A patent/CH622779A5/en not_active IP Right Cessation
1981
- 1981-04-02 HK HK126/81A patent/HK12681A/en unknown
1993
- 1993-05-24 NL NL930035C patent/NL930035I2/en unknown

Also Published As

Publication number	Publication date
PL105940B1 (en)	1979-11-30
BG24805A3 (en)	1978-05-12
BE847968A (en)	1977-05-04
SE7612308L (en)	1977-05-06
DE2549568A1 (en)	1977-05-18
CH623038A5 (en)	1981-05-15
AU498964B2 (en)	1979-03-29
PT65797A (en)	1976-12-01
DE2549568B2 (en)	1980-08-21
RO70295A (en)	1981-08-17
NL930035I2 (en)	1993-10-01
LU88275I2 (en)	1994-02-03
SE423542B (en)	1982-05-10
FI763160A (en)	1977-05-06
FI60704C (en)	1982-03-10
NO145574B (en)	1982-01-11
BG24668A3 (en)	1978-04-12
CH622779A5 (en)	1981-04-30
AU1935876A (en)	1978-05-11
LU76133A1 (en)	1977-06-02
DK146762B (en)	1983-12-27
PL106084B1 (en)	1979-11-30
ES463166A1 (en)	1978-07-16
HK12681A (en)	1981-04-10
BG25079A3 (en)	1978-07-12
NO763608L (en)	1977-05-06
FR2330395A1 (en)	1977-06-03
NL175915C (en)	1985-01-16
FR2330395B1 (en)	1978-12-22
IE43984B1 (en)	1981-07-15
DK146762C (en)	1984-06-12
FI60704B (en)	1981-11-30
GB1516793A (en)	1978-07-05
ZA766622B (en)	1977-10-26
CA1085406A (en)	1980-09-09
IL50817A0 (en)	1977-01-31
BG24803A3 (en)	1978-05-12
IE43984L (en)	1977-05-05
NZ182502A (en)	1978-07-28
DK498476A (en)	1977-05-06
JPS5647185B2 (en)	1981-11-07
IL50817A (en)	1979-07-25
DE2549568C3 (en)	1981-10-29
CS200499B2 (en)	1980-09-15
NL930035I1 (en)	1993-08-02
BG24804A3 (en)	1978-05-12
ES452986A1 (en)	1977-12-16
JPS5259161A (en)	1977-05-16
BG25078A3 (en)	1978-07-12
ATA814276A (en)	1979-02-15
GR61241B (en)	1978-10-12
AT352129B (en)	1979-09-10
PT65797B (en)	1978-05-12
NO145574C (en)	1982-04-21

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NL7805534A (en)	1978-11-28	METHOD FOR PREPARING THERAPEUTIC AGENTS
NL7602919A (en)	1976-09-21	REMOVABLE CONNECTION DEVICE FOR FURNITURE.
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NL7808276A (en)	1979-02-13	Novel 1,3-diphenoxypropan-2-one derivatives, process for their preparation, and medicaments containing the aforementioned derivatives.
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NL7802023A (en)	1978-08-29	NEW MEDICINE COMBINATIONS AND METHOD FOR THE PREPARATION THEREOF.
NL7603203A (en)	1976-10-19	METHOD FOR WINNING NICOTINIC ACID AMIDE.
NL7613342A (en)	1977-06-03	PROCESS FOR PREPARING N, N'-BIS-TRIME-THYLSILYLUREUM.
NL7609553A (en)	1977-03-28	PROCEDURE FOR ADJUSTING THE WORK PROGRESS OF A DISHWASHER.

Legal Events

Date	Code	Title	Description
1979-04-25	BC	A request for examination has been filed
1993-08-02	AC1	Application for a supplementary protection certificate	Free format text: 930035, 930524
1993-10-01	KC1	Grant of a supplementary protection certificate	Free format text: 930035, 961103, EXPIRES:20011102
1996-03-01	AC1	Application for a supplementary protection certificate	Free format text: 0930035, 930524
1997-01-06	V4	Discontinued because of reaching the maximum lifetime of a patent	Free format text: 961103