BG24803A3 - METHOD FOR OBTAINING ISOBUTYL ESTER OF 2,6-DIMETHYL-3-METHOXYCARBONYL 4-(2'-NITROPHENYL)-1,4-DIHYDROPYRIDINE-5-CARBONIC ACID - Google Patents

METHOD FOR OBTAINING ISOBUTYL ESTER OF 2,6-DIMETHYL-3-METHOXYCARBONYL 4-(2'-NITROPHENYL)-1,4-DIHYDROPYRIDINE-5-CARBONIC ACID

Info

Publication number: BG24803A3
Authority: BG; Bulgaria
Prior art keywords: dihydropyridine; methoxycarbonyl; nitrophenyl; dimethyl; obtaining
Prior art date: 1975-11-05

Application number

BG035343A

Other languages

Bulgarian (bg)

Inventor

Egbert Wehinger

Friedrich Bossert

Arent Heise

Stanislav Karda

Kurt Stoepel

Wall Vater

Original Assignee

Неизвестен

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-11-05

Filing date

1976-11-01

Publication date

1978-05-12

1976-11-01 Application filed by Неизвестен filed Critical Неизвестен

1978-05-12 Publication of BG24803A3 publication Critical patent/BG24803A3/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Heart & Thoracic Surgery (AREA)
General Health & Medical Sciences (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

BG035343A 1975-11-05 1976-11-01 METHOD FOR OBTAINING ISOBUTYL ESTER OF 2,6-DIMETHYL-3-METHOXYCARBONYL 4-(2'-NITROPHENYL)-1,4-DIHYDROPYRIDINE-5-CARBONIC ACID BG24803A3 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE2549568A DE2549568C3 (en)	1975-11-05	1975-11-05	2,6-Dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl) -1,4-dihydropyridine-5-carboxylic acid isobutyl ester, several processes for its preparation and pharmaceuticals containing it

Publications (1)

Publication Number	Publication Date
BG24803A3 true BG24803A3 (en)	1978-05-12

Family

ID=5960951

Family Applications (6)

Application Number	Title	Priority Date	Filing Date
BG034575A BG24668A3 (en)	1975-11-05	1976-11-01	METHOD FOR OBTAINING ISOBUTYL ESTER OF 2-6-DIMETHYL-3-METHOXYCARBONYL-4-(2'-NITROPHENYL)-1,4-dihydropyridine-5-CARBONIC ACID
BG035341A BG25078A3 (en)	1975-11-05	1976-11-01	METHOD FOR OBTAINING ISOBUTYL ESTER OF 2,6-DIMETHYL-3-METHOXYCARBONYL-4-(NITROPHENYL)-1,4-dihydropyridine-5-carboxylic acid
BG035343A BG24803A3 (en)	1975-11-05	1976-11-01	METHOD FOR OBTAINING ISOBUTYL ESTER OF 2,6-DIMETHYL-3-METHOXYCARBONYL 4-(2'-NITROPHENYL)-1,4-DIHYDROPYRIDINE-5-CARBONIC ACID
BG035342A BG25079A3 (en)	1975-11-05	1976-11-01	METHOD FOR OBTAINING ISOBUTYL ESTER OF 2,6-DIMETHYL-3-METHOXYCARBONYL-4-(2'-NITROPHENYL)-1,4 DIHYDROPYRIDINE-5-CARBONIC ACID
BG035345A BG24805A3 (en)	1975-11-05	1976-11-01	METHOD FOR OBTAINING ISOBUTYL ESTER OF 2,6-DIMETHYL-3-METHOXYCARBONYL-4(2'-NITROPHENYL)-1,4-dihydropyridine-5-carboxylic acid
BG035344A BG24804A3 (en)	1975-11-05	1976-11-01	METHOD FOR OBTAINING ISOBUTYL ESTER OF 2,6-DIMETHYL-3-METHOXYCARBONYL-4(2'-NITROPHENYL)-1,4-dihydropyridine-5-carboxylic acid

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
BG034575A BG24668A3 (en)	1975-11-05	1976-11-01	METHOD FOR OBTAINING ISOBUTYL ESTER OF 2-6-DIMETHYL-3-METHOXYCARBONYL-4-(2'-NITROPHENYL)-1,4-dihydropyridine-5-CARBONIC ACID
BG035341A BG25078A3 (en)	1975-11-05	1976-11-01	METHOD FOR OBTAINING ISOBUTYL ESTER OF 2,6-DIMETHYL-3-METHOXYCARBONYL-4-(NITROPHENYL)-1,4-dihydropyridine-5-carboxylic acid

Family Applications After (3)

Application Number	Title	Priority Date	Filing Date
BG035342A BG25079A3 (en)	1975-11-05	1976-11-01	METHOD FOR OBTAINING ISOBUTYL ESTER OF 2,6-DIMETHYL-3-METHOXYCARBONYL-4-(2'-NITROPHENYL)-1,4 DIHYDROPYRIDINE-5-CARBONIC ACID
BG035345A BG24805A3 (en)	1975-11-05	1976-11-01	METHOD FOR OBTAINING ISOBUTYL ESTER OF 2,6-DIMETHYL-3-METHOXYCARBONYL-4(2'-NITROPHENYL)-1,4-dihydropyridine-5-carboxylic acid
BG035344A BG24804A3 (en)	1975-11-05	1976-11-01	METHOD FOR OBTAINING ISOBUTYL ESTER OF 2,6-DIMETHYL-3-METHOXYCARBONYL-4(2'-NITROPHENYL)-1,4-dihydropyridine-5-carboxylic acid

Country Status (27)

Country	Link
JP (1)	JPS5259161A (en)
AT (1)	AT352129B (en)
AU (1)	AU498964B2 (en)
BE (1)	BE847968A (en)
BG (6)	BG24668A3 (en)
CA (1)	CA1085406A (en)
CH (2)	CH623038A5 (en)
CS (1)	CS200499B2 (en)
DE (1)	DE2549568C3 (en)
DK (1)	DK146762C (en)
ES (2)	ES452986A1 (en)
FI (1)	FI60704C (en)
FR (1)	FR2330395A1 (en)
GB (1)	GB1516793A (en)
GR (1)	GR61241B (en)
HK (1)	HK12681A (en)
IE (1)	IE43984B1 (en)
IL (1)	IL50817A (en)
LU (2)	LU88275I2 (en)
NL (2)	NL175915C (en)
NO (1)	NO145574C (en)
NZ (1)	NZ182502A (en)
PL (2)	PL106084B1 (en)
PT (1)	PT65797B (en)
RO (1)	RO70295A (en)
SE (1)	SE423542B (en)
ZA (1)	ZA766622B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4146630A (en) *	1976-11-12	1979-03-27	Boehringer Mannheim Gmbh	Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers
JPS55301A (en) *	1978-02-14	1980-01-05	Yamanouchi Pharmaceut Co Ltd	1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
DE3212736A1 (en) *	1982-04-06	1983-10-13	Bayer Ag, 5090 Leverkusen	USE OF DIHYDROPYRIDINES IN MEDICINAL PRODUCTS WITH SALIDIURETIC EFFECT
DE3222367A1 (en) *	1982-06-15	1983-12-15	Bayer Ag, 5090 Leverkusen	Use of 1,4-dihydropyridines in antiarteriosclerotics and preparation thereof
JPS5982192U (en) *	1982-11-27	1984-06-02	エムケ−精工株式会社	door
DE3312216A1 (en) *	1983-04-05	1984-10-11	Bayer Ag, 5090 Leverkusen	METHOD FOR PRODUCING SYMMETRIC 1,4-DIHYDROPYRIDINE CARBONIC ACID ESTERS
DE3312283A1 (en) *	1983-04-05	1984-10-18	Bayer Ag, 5090 Leverkusen	METHOD FOR PRODUCING UNBALANCED 1,4-DIHYDROPYRIDINE CARBONIC ACID ESTERS
US4794111A (en) *	1984-05-23	1988-12-27	Bayer Aktiengesellschaft	Dihydropyridine preparations containing β-blockers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2117571C3 (en) *	1971-04-10	1979-10-11	Bayer Ag, 5090 Leverkusen	Asymmetrical 1,4-dihydropyridine-33-dicarboxylic acid esters, process for their preparation and their use as pharmaceuticals

1975
- 1975-11-05 DE DE2549568A patent/DE2549568C3/en not_active Expired
1976
- 1976-10-22 NO NO763608A patent/NO145574C/en unknown
- 1976-10-29 JP JP51129540A patent/JPS5259161A/en active Granted
- 1976-11-01 BG BG034575A patent/BG24668A3/en unknown
- 1976-11-01 BG BG035341A patent/BG25078A3/en unknown
- 1976-11-01 BG BG035343A patent/BG24803A3/en unknown
- 1976-11-01 BG BG035342A patent/BG25079A3/en unknown
- 1976-11-01 BG BG035345A patent/BG24805A3/en unknown
- 1976-11-01 BG BG035344A patent/BG24804A3/en unknown
- 1976-11-02 RO RO7688294A patent/RO70295A/en unknown
- 1976-11-02 NZ NZ182502A patent/NZ182502A/en unknown
- 1976-11-02 CH CH1381976A patent/CH623038A5/en not_active IP Right Cessation
- 1976-11-02 CS CS767068A patent/CS200499B2/en unknown
- 1976-11-02 IL IL50817A patent/IL50817A/en unknown
- 1976-11-02 GB GB45501/76A patent/GB1516793A/en not_active Expired
- 1976-11-03 NL NLAANVRAGE7612198,A patent/NL175915C/en not_active IP Right Cessation
- 1976-11-03 FI FI763160A patent/FI60704C/en not_active IP Right Cessation
- 1976-11-03 PL PL1976193438A patent/PL106084B1/en unknown
- 1976-11-03 PL PL1976201800A patent/PL105940B1/en unknown
- 1976-11-03 AT AT814276A patent/AT352129B/en not_active IP Right Cessation
- 1976-11-04 CA CA264,921A patent/CA1085406A/en not_active Expired
- 1976-11-04 BE BE172063A patent/BE847968A/en not_active IP Right Cessation
- 1976-11-04 IE IE2458/76A patent/IE43984B1/en not_active IP Right Cessation
- 1976-11-04 GR GR52093A patent/GR61241B/en unknown
- 1976-11-04 ES ES452986A patent/ES452986A1/en not_active Expired
- 1976-11-04 PT PT65797A patent/PT65797B/en unknown
- 1976-11-04 DK DK498476A patent/DK146762C/en not_active IP Right Cessation
- 1976-11-04 ZA ZA766622A patent/ZA766622B/en unknown
- 1976-11-04 LU LU88275C patent/LU88275I2/xx unknown
- 1976-11-04 LU LU76133A patent/LU76133A1/xx active Protection Beyond IP Right Term
- 1976-11-04 SE SE7612308A patent/SE423542B/en not_active IP Right Cessation
- 1976-11-05 AU AU19358/76A patent/AU498964B2/en not_active Expired
- 1976-11-05 FR FR7633488A patent/FR2330395A1/en active Granted
1977
- 1977-10-13 ES ES463166A patent/ES463166A1/en not_active Expired
1980
- 1980-07-23 CH CH567880A patent/CH622779A5/en not_active IP Right Cessation
1981
- 1981-04-02 HK HK126/81A patent/HK12681A/en unknown
1993
- 1993-05-24 NL NL930035C patent/NL930035I2/en unknown

Also Published As

Publication number	Publication date
AT352129B (en)	1979-09-10
FI60704B (en)	1981-11-30
BG24804A3 (en)	1978-05-12
RO70295A (en)	1981-08-17
HK12681A (en)	1981-04-10
LU88275I2 (en)	1994-02-03
GB1516793A (en)	1978-07-05
BG24668A3 (en)	1978-04-12
CS200499B2 (en)	1980-09-15
IE43984L (en)	1977-05-05
NL930035I2 (en)	1993-10-01
CA1085406A (en)	1980-09-09
NL930035I1 (en)	1993-08-02
IL50817A (en)	1979-07-25
SE7612308L (en)	1977-05-06
PT65797A (en)	1976-12-01
IE43984B1 (en)	1981-07-15
DK146762C (en)	1984-06-12
GR61241B (en)	1978-10-12
NZ182502A (en)	1978-07-28
DE2549568C3 (en)	1981-10-29
NO145574C (en)	1982-04-21
DE2549568B2 (en)	1980-08-21
ES463166A1 (en)	1978-07-16
ES452986A1 (en)	1977-12-16
AU1935876A (en)	1978-05-11
PL106084B1 (en)	1979-11-30
JPS5647185B2 (en)	1981-11-07
ATA814276A (en)	1979-02-15
CH622779A5 (en)	1981-04-30
CH623038A5 (en)	1981-05-15
PL105940B1 (en)	1979-11-30
FR2330395B1 (en)	1978-12-22
BG25078A3 (en)	1978-07-12
DE2549568A1 (en)	1977-05-18
NL7612198A (en)	1977-05-09
BE847968A (en)	1977-05-04
NO145574B (en)	1982-01-11
PT65797B (en)	1978-05-12
AU498964B2 (en)	1979-03-29
NL175915C (en)	1985-01-16
BG24805A3 (en)	1978-05-12
DK498476A (en)	1977-05-06
FI763160A7 (en)	1977-05-06
JPS5259161A (en)	1977-05-16
IL50817A0 (en)	1977-01-31
LU76133A1 (en)	1977-06-02
SE423542B (en)	1982-05-10
NO763608L (en)	1977-05-06
ZA766622B (en)	1977-10-26
FR2330395A1 (en)	1977-06-03
BG25079A3 (en)	1978-07-12
FI60704C (en)	1982-03-10
DK146762B (en)	1983-12-27

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IT1088061B (en)	1985-06-04	PROCEDURE FOR PREPARING BICARBOXYLIC ACID DIHESTERS
DK144127C (en)	1982-06-01	METHOD OF ANALOGUE FOR THE PREPARATION OF LYRIC ACID OR 9,10-DIHYDROLYRIC ACIDAMIDS OR ACID ADDITION SALTS THEREOF
ATA292078A (en)	1979-12-15	PROCESS FOR THE PREPARATION OF NEW 9-AMINODESOXYCLAVULANIC ACID DERIVATIVES
AR211938A1 (en)	1978-04-14	PROCEDURE FOR PREPARING DERIVATIVES OF 4- (3,5-DITERBUTIL-4-HYDROXY-PHENYLACILAMINE) -PHENOXIALKYLCARBOXYL ACIDS
BG24803A3 (en)	1978-05-12	METHOD FOR OBTAINING ISOBUTYL ESTER OF 2,6-DIMETHYL-3-METHOXYCARBONYL 4-(2'-NITROPHENYL)-1,4-DIHYDROPYRIDINE-5-CARBONIC ACID
DK142544C (en)	1981-08-17	METHOD OF ANALOGUE FOR THE PREPARATION OF 2- (N-PROPARGYL-N-PHENYLAMINO) -IMIDAZOLINE- (2) -DERIVATIVES OR PHYSIOLOGICALLY ACCEPTABLE ACID ADDITION SALTS
SU584052A1 (en)	1977-12-15	Method of obtaining refractory combinations
PL209256A1 (en)	1979-06-04	METHOD OF MAKING 2-HYDRAZONOPROPIONIC ACID DERIVATIVES
BG26388A3 (en)	1979-03-15	METHOD FOR OBTAINING DERIVATIVES OF XANTHENIC ACID
SE431980B (en)	1984-03-12	METHOD OF PREPARING TIOCARBAMIC ACID ESTERS
BG27365A3 (en)	1979-10-12	METHOD FOR OBTAINING SOLUTIONS OF PERPROPIONIC ACID
BG27364A3 (en)	1979-10-12	METHOD FOR OBTAINING SOLUTIONS OF PERPROPIONIC ACID
DD135388A5 (en)	1979-05-02	PROCESS FOR THE PREPARATION OF OXAZOLINOAZETIDINYLPENIC CARBOXYLIC ACID DERIVATIVES
AT347434B (en)	1978-12-27	PROCESS FOR THE PREPARATION OF 2- (3-BENZYOLPHENYL) -PROPIONIC ACID
DD132659A5 (en)	1978-10-18	PROCESS FOR PREPARING 1-AZIRIDINE CARBOXYESURE DERIVATIVES OF GENERAL FORMULA I
ATA708377A (en)	1979-09-15	PROCESS FOR THE PREPARATION OF 2- (3-BENZOYL-PHENYL) -PROPIONITRILE
AR212814A1 (en)	1978-10-13	PROCEDURE FOR THE PREPARATION OF N-2'-CARBOXIFENIL-4-CHLOROANTRANILICO ACID DERIVATIVES
BG24945A3 (en)	1978-06-15	METHOD FOR OBTAINING ESTERS OF PENTAHALOGENPHENYLMALONIC ACID
DD132267A5 (en)	1978-09-13	PROCESS FOR THE PREPARATION OF ANTHRACHINONE DERIVATIVES
PL202492A1 (en)	1979-07-30	METHOD OF OBTAINING 1,4-Piperizine-3-dicarboxylic acid esters
PL204553A1 (en)	1979-06-04	METHOD OF MANUFACTURING NEW DERIVATIVES OF INOLYGLIXIC ACID