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NL300337I2 - Gebruik van ET-743 in combinatie-therapie met dexamethasone voor de behandeling van kanker - Google Patents

Gebruik van ET-743 in combinatie-therapie met dexamethasone voor de behandeling van kanker

Info

Publication number
NL300337I2
NL300337I2 NL300337C NL300337C NL300337I2 NL 300337 I2 NL300337 I2 NL 300337I2 NL 300337 C NL300337 C NL 300337C NL 300337 C NL300337 C NL 300337C NL 300337 I2 NL300337 I2 NL 300337I2
Authority
NL
Netherlands
Prior art keywords
dexamethasone
cancer
treatment
combination therapy
therapy
Prior art date
Application number
NL300337C
Other languages
English (en)
Other versions
NL300337I1 (nl
Original Assignee
Pharma Mar Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9911183.3A external-priority patent/GB9911183D0/en
Priority claimed from GBGB9911346.6A external-priority patent/GB9911346D0/en
Priority claimed from GBGB9918534.0A external-priority patent/GB9918534D0/en
Priority claimed from GBGB9927005.0A external-priority patent/GB9927005D0/en
Priority claimed from GBGB9927106.6A external-priority patent/GB9927106D0/en
Priority claimed from GB0007637A external-priority patent/GB0007637D0/en
Application filed by Pharma Mar Sa filed Critical Pharma Mar Sa
Publication of NL300337I1 publication Critical patent/NL300337I1/nl
Publication of NL300337I2 publication Critical patent/NL300337I2/nl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NL300337C 1999-05-13 2008-02-22 Gebruik van ET-743 in combinatie-therapie met dexamethasone voor de behandeling van kanker NL300337I2 (nl)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GBGB9911183.3A GB9911183D0 (en) 1999-05-13 1999-05-13 Treatment of cancers
GBGB9911346.6A GB9911346D0 (en) 1999-05-14 1999-05-14 Treatment of cancers
GBGB9918534.0A GB9918534D0 (en) 1999-08-05 1999-08-05 Treatment of cancers
GBGB9927005.0A GB9927005D0 (en) 1999-11-15 1999-11-15 Treatment of cancers
GBGB9927106.6A GB9927106D0 (en) 1999-11-16 1999-11-16 Cancer treatment
GB0007637A GB0007637D0 (en) 2000-03-29 2000-03-29 Antitumour compound
EP00927584A EP1176964B8 (en) 1999-05-13 2000-05-15 Uses of et743 for treating cancer

Publications (2)

Publication Number Publication Date
NL300337I1 NL300337I1 (nl) 2008-05-01
NL300337I2 true NL300337I2 (nl) 2008-09-01

Family

ID=27546594

Family Applications (1)

Application Number Title Priority Date Filing Date
NL300337C NL300337I2 (nl) 1999-05-13 2008-02-22 Gebruik van ET-743 in combinatie-therapie met dexamethasone voor de behandeling van kanker

Country Status (32)

Country Link
US (1) US8119638B2 (nl)
EP (3) EP1702618B1 (nl)
JP (2) JP2002544231A (nl)
KR (1) KR20020019914A (nl)
CN (2) CN100477993C (nl)
AR (1) AR028476A1 (nl)
AT (3) ATE338552T1 (nl)
AU (2) AU777417B2 (nl)
BG (1) BG65680B1 (nl)
BR (1) BR0010531A (nl)
CA (1) CA2373794C (nl)
CY (4) CY1105818T1 (nl)
CZ (1) CZ301482B6 (nl)
DE (4) DE60030554T8 (nl)
DK (3) DK1702618T3 (nl)
ES (2) ES2294756T3 (nl)
FR (1) FR08C0013I2 (nl)
HU (2) HU229866B1 (nl)
IL (2) IL146434A0 (nl)
LU (1) LU91418I2 (nl)
MX (1) MXPA01011562A (nl)
MY (1) MY164077A (nl)
NL (1) NL300337I2 (nl)
NO (2) NO324564B1 (nl)
NZ (1) NZ515423A (nl)
PL (1) PL198185B1 (nl)
PT (3) PT1176964E (nl)
SI (3) SI1702618T1 (nl)
SK (1) SK287580B6 (nl)
TR (1) TR200103819T2 (nl)
UA (1) UA74782C2 (nl)
WO (1) WO2000069441A1 (nl)

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MY164077A (en) 1999-05-13 2017-11-30 Pharma Mar Sa Compositions and uses of et743 for treating cancer
MXPA02011319A (es) 2000-05-15 2003-06-06 Pharma Mar Sa Analogos antitumorales de ecteinascidina 743.
DE60143911D1 (de) * 2000-11-06 2011-03-03 Pharma Mar Sa Antitumorzusammensetzungen welche ecteinascidin 743 enthalten
GB0117402D0 (en) * 2001-07-17 2001-09-05 Pharma Mar Sa New antitumoral derivatives of et-743
PL368458A1 (en) * 2001-10-19 2005-03-21 Pharmamar S.A. Improved use of antitumoral compound in cancer therapy
GB0202544D0 (en) 2002-02-04 2002-03-20 Pharma Mar Sa The synthesis of naturally occuring ecteinascidins and related compounds
GB0324201D0 (en) * 2003-10-15 2003-11-19 Pharma Mar Sau Improved antitumoral combinations
CA2544320A1 (en) * 2003-11-13 2005-06-02 Pharma Mar, S.A.U. Method of treating cancer using a combination comprising et-743 and 5-fluorouracil
CN1897949A (zh) * 2003-11-14 2007-01-17 马尔药品公司 包含使用et－743和紫杉醇来治疗癌症的联合疗法
GB0326486D0 (en) * 2003-11-14 2003-12-17 Pharma Mar Sau Combination treatment
CA2573072A1 (en) * 2004-07-09 2006-01-19 Rafael Rosell Costa Use of ecteinascidin in the treatment of cancer in patients with low level of brca1
CN101119750B (zh) * 2004-10-26 2013-03-06 法马马私人股份有限公司 抗癌治疗
DE602005001833T2 (de) 2004-10-29 2008-04-17 Pharma Mar S.A., Sociedad Unipersonal Zusammensetzungen enthaltend Ecteinascidin und einen Disaccharide
GB0522082D0 (en) * 2005-10-31 2005-12-07 Pharma Mar Sa Formulations
MX2008014404A (es) * 2006-05-12 2008-11-27 Pharma Mar Sa Tratamientos anticancer con combinacion de docetaxel y ecteinascidin.
JP2011500046A (ja) * 2007-10-19 2011-01-06 ファルマ・マール・ソシエダード・アノニマ Ｅｔ−７４３治療のための予後分子マーカー
MX2018009088A (es) * 2016-02-04 2018-09-03 Jiangsu Hengrui Medicine Co Composicion farmaceutica inyectable que incluye trabectedina para uso gastrointestinal externo y metodo para la fabricacion de la misma.
JOP20190254A1 (ar) 2017-04-27 2019-10-27 Pharma Mar Sa مركبات مضادة للأورام
WO2020239478A1 (en) 2019-05-28 2020-12-03 Pharma Mar, S.A. Trabectedin for treating sarcomas based on genomic markers
CN112574234B (zh) * 2019-09-27 2022-05-24 江苏恒瑞医药股份有限公司 一种海鞘素衍生物的制备方法
ES2981253T3 (es) 2020-04-15 2024-10-08 Ever Valinject Gmbh Composición que comprende trabectedina y un aminoácido
US20230226051A1 (en) 2022-01-20 2023-07-20 Extrovis Ag Trabectedin composition

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US5149804A (en) * 1990-11-30 1992-09-22 The Board Of Trustees Of The University Of Illinois Ecteinascidins 736 and 722
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SK288017B6 (sk) 2000-04-12 2012-11-05 Pharma Mar, S. A. Ecteinascidin having a fused five ring system with a 1,4 bridge, pharmaceutical composition containing it and use thereof
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DE60143911D1 (de) 2000-11-06 2011-03-03 Pharma Mar Sa Antitumorzusammensetzungen welche ecteinascidin 743 enthalten
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GB0312407D0 (en) 2003-05-29 2003-07-02 Pharma Mar Sau Treatment
GB0324201D0 (en) 2003-10-15 2003-11-19 Pharma Mar Sau Improved antitumoral combinations
CA2544320A1 (en) 2003-11-13 2005-06-02 Pharma Mar, S.A.U. Method of treating cancer using a combination comprising et-743 and 5-fluorouracil
GB0326486D0 (en) 2003-11-14 2003-12-17 Pharma Mar Sau Combination treatment
CN1897949A (zh) 2003-11-14 2007-01-17 马尔药品公司 包含使用et－743和紫杉醇来治疗癌症的联合疗法
CA2573072A1 (en) 2004-07-09 2006-01-19 Rafael Rosell Costa Use of ecteinascidin in the treatment of cancer in patients with low level of brca1
CA2583464A1 (en) 2004-09-29 2006-04-06 Pharma Mar S.A., Sociedad Unipersonal Ecteinascidin compounds as anti -inflammatory agents
CN101119750B (zh) 2004-10-26 2013-03-06 法马马私人股份有限公司 抗癌治疗
DE602005001833T2 (de) 2004-10-29 2008-04-17 Pharma Mar S.A., Sociedad Unipersonal Zusammensetzungen enthaltend Ecteinascidin und einen Disaccharide
DE602006020335D1 (de) 2005-11-25 2011-04-07 Pharma Mar Sa Verwendung von parp-1-hemmern
MX2008014404A (es) 2006-05-12 2008-11-27 Pharma Mar Sa Tratamientos anticancer con combinacion de docetaxel y ecteinascidin.

Also Published As

Publication number Publication date
EP1702618A2 (en) 2006-09-20
NZ515423A (en) 2004-04-30
HU229866B1 (en) 2014-10-28
DK1716853T3 (da) 2011-06-27
BR0010531A (pt) 2002-06-04
AU2005200180B9 (en) 2008-05-29
PT1702618E (pt) 2008-01-11
ATE375795T1 (de) 2007-11-15
EP1716853A3 (en) 2006-11-15
IL146434A0 (en) 2002-07-25
CY1112753T1 (el) 2016-02-10
FR08C0013I1 (nl) 2008-05-30
CY1105818T1 (el) 2011-02-02
DE60036826D1 (de) 2007-11-29
EP1702618A3 (en) 2006-12-27
JP2012149095A (ja) 2012-08-09
DE60036826T2 (de) 2008-08-28
DE60030554T2 (de) 2007-09-13
ES2272279T3 (es) 2007-05-01
SK287580B6 (sk) 2011-03-04
JP5777562B2 (ja) 2015-09-09
EP1176964B1 (en) 2006-09-06
CY1107143T1 (el) 2010-07-28
TR200103819T2 (tr) 2002-04-22
HUS1500001I1 (hu) 2016-08-29
CY2008007I2 (el) 2009-11-04
ATE500830T1 (de) 2011-03-15
DK1176964T3 (da) 2007-01-15
EP1176964B8 (en) 2007-10-10
MXPA01011562A (es) 2002-07-30
NO20015516L (no) 2002-01-11
LU91418I2 (fr) 2008-05-13
KR20020019914A (ko) 2002-03-13
US20070275942A1 (en) 2007-11-29
CZ20014081A3 (cs) 2002-11-13
CA2373794C (en) 2005-10-11
AR028476A1 (es) 2003-05-14
HUP0201187A2 (en) 2002-09-28
ATE338552T1 (de) 2006-09-15
SI1176964T1 (sl) 2007-02-28
NO20015516D0 (no) 2001-11-12
AU4597500A (en) 2000-12-05
DE60045720D1 (de) 2011-04-21
CN1360503A (zh) 2002-07-24
PL198185B1 (pl) 2008-06-30
AU2005200180A1 (en) 2005-02-10
NO2008005I1 (no) 2008-06-09
UA74782C2 (uk) 2006-02-15
HUP0201187A3 (en) 2002-11-28
PL352931A1 (en) 2003-09-22
SI1716853T1 (sl) 2011-10-28
DK1702618T3 (da) 2008-02-25
AU2005200180B2 (en) 2007-12-13
AU777417B2 (en) 2004-10-14
US8119638B2 (en) 2012-02-21
NO2008005I2 (nl) 2010-09-27
BG65680B1 (bg) 2009-06-30
EP1702618B1 (en) 2007-10-17
CZ301482B6 (cs) 2010-03-17
DE60030554D1 (de) 2006-10-19
EP1716853B1 (en) 2011-03-09
BG106171A (en) 2002-06-28
JP2002544231A (ja) 2002-12-24
PT1176964E (pt) 2007-01-31
CA2373794A1 (en) 2000-11-23
DE60030554T8 (de) 2008-01-10
LU91418I9 (nl) 2019-01-02
SK16442001A3 (sk) 2002-03-05
ES2294756T3 (es) 2008-04-01
NO324564B1 (no) 2007-11-19
SI1702618T1 (sl) 2008-02-29
CN1679631A (zh) 2005-10-12
EP1176964A1 (en) 2002-02-06
EP1716853B9 (en) 2011-09-28
FR08C0013I2 (fr) 2009-10-30
MY164077A (en) 2017-11-30
EP1716853A2 (en) 2006-11-02
IL146434A (en) 2008-03-20
WO2000069441A1 (en) 2000-11-23
NL300337I1 (nl) 2008-05-01
PT1716853E (pt) 2011-05-12
CY2008007I1 (el) 2009-11-04
DE122008000013I1 (de) 2008-08-07
CN100477993C (zh) 2009-04-15

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