NL267508A - - Google Patents
Info
- Publication number
- NL267508A NL267508A NL267508DA NL267508A NL 267508 A NL267508 A NL 267508A NL 267508D A NL267508D A NL 267508DA NL 267508 A NL267508 A NL 267508A
- Authority
- NL
- Netherlands
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4529260A | 1960-07-26 | 1960-07-26 | |
| US118261A US3176019A (en) | 1960-07-26 | 1961-06-20 | Substituted aminobutynyl acetates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL267508A true NL267508A (zh) |
Family
ID=26722613
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL267508D NL267508A (zh) | 1960-07-26 | ||
| NL124473D NL124473C (zh) | 1960-07-26 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL124473D NL124473C (zh) | 1960-07-26 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3176019A (zh) |
| BE (1) | BE606560A (zh) |
| CH (1) | CH421078A (zh) |
| DE (1) | DE1216866B (zh) |
| DK (1) | DK113854B (zh) |
| ES (1) | ES269353A1 (zh) |
| FR (1) | FR1325M (zh) |
| GB (1) | GB940540A (zh) |
| NL (2) | NL124473C (zh) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5736577A (en) * | 1995-01-31 | 1998-04-07 | Sepracor, Inc. | Methods and compositions for treating urinary incontinence using optically pure (S)-oxybutynin |
| US3864388A (en) * | 1970-12-29 | 1975-02-04 | Sumitomo Chemical Co | Alkynyl esters of {60 -alkoxy-{60 -phenyl alkenoic acid |
| US5036107A (en) * | 1986-06-27 | 1991-07-30 | Marion Merrell Dow Inc. | 1,7-substituted heptyn-2-ones and use |
| US4957941A (en) * | 1987-11-16 | 1990-09-18 | United Pharmaceuticals, Inc. | Anti-spasmdoic agents having an acetylenic bond |
| IL91377A (en) * | 1988-09-14 | 1996-09-12 | Nippon Shinyaku Co Ltd | Derivatives of botinylamine glycolate |
| US5532278A (en) * | 1995-01-31 | 1996-07-02 | Sepracor, Inc. | Methods and compositions for treating urinary incontinence using optically pure (S)-oxybutynin |
| US5677346A (en) * | 1995-01-31 | 1997-10-14 | Sepracor, Inc. | Treating urinary incontinence using (S)-desethyloxybutynin |
| WO1998001125A2 (en) * | 1996-07-09 | 1998-01-15 | Sepracor, Inc. | Dextrorotatory isomers of oxybutynin and desethyloxybutynin in the treatment of gastrointestinal hyperactivity |
| US6140529A (en) * | 1998-10-22 | 2000-10-31 | Sepracor Inc. | Synthesis of optically active cyclohexylphenylglycolate esters |
| US5973182A (en) * | 1998-10-22 | 1999-10-26 | Sepracor Inc. | Carbonate Intermediates useful in the preparation of optically active cyclohexylphenylglycolate esters |
| DE60143477D1 (de) * | 2000-04-26 | 2010-12-30 | Watson Pharmaceuticals Inc | Verminderung der nebenwirkungen bei der oxybutynin-therapie |
| US7179483B2 (en) | 2000-04-26 | 2007-02-20 | Watson Pharmaceuticals, Inc. | Compositions and methods for transdermal oxybutynin therapy |
| CA2464223C (en) | 2001-10-26 | 2009-05-26 | Pharmacia & Upjohn Company | Quarternary ammonium compounds and their use as antimuscarinic agents |
| ATE419236T1 (de) | 2002-07-08 | 2009-01-15 | Ranbaxy Lab Ltd | 3,6-disubstituierte azabicyclo-3.1.0 hexan- derivate als muscarinische rezeptorantagonisten |
| WO2004014853A1 (en) * | 2002-07-31 | 2004-02-19 | Ranbaxy Laboratories Limited | 3,6-disubstituted azabicyclo [3.1.0]hexane derivatives useful as muscarinic receptor antagonists |
| EP1545508A4 (en) * | 2002-08-09 | 2009-11-25 | Ranbaxy Lab Ltd | 3,6-DISUBSTITUTED AZABICYCLO ¬3.1.0 HEXANE DERIVATIVES AS USEFUL AS MUSCARINIC RECEPTOR AGONISTS |
| JP2006501236A (ja) * | 2002-08-23 | 2006-01-12 | ランバクシー ラボラトリーズ リミテッド | ムスカリン性レセプター拮抗薬としてのフルオロおよびスルホニルアミノ含有３，６−二置換アザビシクロ（３．１．０）ヘキサン誘導体 |
| TW200412945A (en) | 2002-10-25 | 2004-08-01 | Upjohn Co | Quaternary ammonium compounds |
| ATE400553T1 (de) | 2002-12-10 | 2008-07-15 | Ranbaxy Lab Ltd | 3,6-disubstituierte azabicyclo 3.1.0 - hexanderivative als antagonisten des muscarinrezeptors |
| EP1583741A1 (en) * | 2002-12-23 | 2005-10-12 | Ranbaxy Laboratories, Limited | 1-substituted-3-pyrrolidine derivatives as muscarinic receptor antagonists |
| US7501443B2 (en) * | 2002-12-23 | 2009-03-10 | Ranbaxy Laboratories Limited | Flavaxate derivatives as muscarinic receptor antagonists |
| US7488748B2 (en) | 2003-01-28 | 2009-02-10 | Ranbaxy Laboratories Limited | 3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists |
| EP1618091A1 (en) * | 2003-04-09 | 2006-01-25 | Ranbaxy Laboratories, Ltd. | Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists |
| JP2006514978A (ja) * | 2003-04-10 | 2006-05-18 | ランバクシー ラボラトリーズ リミテッド | ムスカリン受容体アンタゴニストである置換アザビシクロヘキサン誘導体 |
| EP1615887A1 (en) | 2003-04-10 | 2006-01-18 | Ranbaxy Laboratories, Ltd. | Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists |
| EA009387B1 (ru) * | 2003-04-11 | 2007-12-28 | Рэнбакси Лабораториз Лимитед | Азабициклические производные в качестве антагонистов мускаринового рецептора |
| ATE419246T1 (de) * | 2004-06-16 | 2009-01-15 | Ranbaxy Lab Ltd | Als antagonisten des muscarinrezeptors geeignete xanthinderivate |
| US20080262075A1 (en) * | 2004-08-19 | 2008-10-23 | Ranbaxy Laboratories Limited | Pyrrolidine Derivatives as Muscarinic Receptor Antagonists |
| US20080280883A1 (en) * | 2004-09-24 | 2008-11-13 | Mohammad Salman | Muscarinic Receptor Antagonists |
| US20090105221A1 (en) * | 2004-09-29 | 2009-04-23 | Ranbaxy Laboratories Limited | Muscarinic receptor antagonists |
| WO2006054162A1 (en) * | 2004-11-19 | 2006-05-26 | Ranbaxy Laboratories Limited | Azabicyclic muscarinic receptor antagonists |
| US20100035954A1 (en) * | 2004-12-15 | 2010-02-11 | Mohammad Salman | Acid addition salts of muscarinic receptor antagonists |
| EP1888525A1 (en) * | 2005-05-03 | 2008-02-20 | Ranbaxy Laboratories Limited | 3,6-disubstituted azabicyclo [3.1.0]hexane derivatives as muscarinic receptor antagonists |
| BRPI0617674A2 (pt) | 2005-10-19 | 2011-08-02 | Ranbaxy Lab Ltd | composições farmacêuticas e seus usos |
| US20090010923A1 (en) * | 2007-04-24 | 2009-01-08 | University Of Maryland, Baltimore | Treatment of cancer with anti-muscarinic receptor agents |
| US20110087042A1 (en) * | 2008-02-04 | 2011-04-14 | Matrix Laboratories Limited | Crystalline oxybutynin and process for preparing the same |
| WO2011137054A1 (en) | 2010-04-30 | 2011-11-03 | Merck Sharp & Dohme Corp. | Novel beta 3 adrenergic receptor agonists |
| TW201208667A (en) | 2010-08-03 | 2012-03-01 | Altherx Inc | Pharmaceutical combinations |
| US9907767B2 (en) | 2010-08-03 | 2018-03-06 | Velicept Therapeutics, Inc. | Pharmaceutical compositions and the treatment of overactive bladder |
| CN104684549A (zh) | 2012-02-09 | 2015-06-03 | 奥瑟克斯公司 | 治疗膀胱过度活动症的毒蕈碱性受体拮抗剂和β-3肾上腺素能受体激动剂的组合 |
| EP3226849A4 (en) | 2014-12-03 | 2018-05-09 | Velicept Therapeutics, Inc. | Compositions and methods of using modified release solabegron for lower urinary tract symptoms |
| WO2017070689A2 (en) | 2015-10-23 | 2017-04-27 | Velicept Therapeutics, Inc. | Solabegron zwitterion and uses thereof |
| SG11202007226UA (en) | 2018-01-30 | 2020-08-28 | Apnimed Inc Delaware | Methods and compositions for treating sleep apnea |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE895595C (de) * | 1943-09-29 | 1953-11-05 | Basf Ag | Verfahren zur Herstellung von Aminoalkinolen |
| DE1003209B (de) * | 1953-03-24 | 1957-02-28 | Basf Ag | Verfahren zur Herstellung spasmolytisch wirksamer basischer Carbinole |
| US2867619A (en) * | 1956-11-05 | 1959-01-06 | Lakeside Lab Inc | Aminoalkynyl-n-alkylpiperidine carboxylates |
| DE1083254B (de) * | 1957-04-01 | 1960-06-15 | Lakeside Lab In | Verfahren zur Herstellung von blutdrucksenkenden N-disubstituierten Diaminoalkinen, deren Saeureadditionssalzen oder quaternaeren Ammoniumsalzen |
| DE1100617B (de) * | 1959-10-22 | 1961-03-02 | Basf Ag | Verfahren zur Herstellung von 1-Dialkylamino-4-hydroxy-acetylenen-(2) |
-
0
- NL NL267508D patent/NL267508A/xx unknown
- NL NL124473D patent/NL124473C/xx active
-
1961
- 1961-06-20 US US118261A patent/US3176019A/en not_active Expired - Lifetime
- 1961-07-19 DE DEM49737A patent/DE1216866B/de active Pending
- 1961-07-20 CH CH856161A patent/CH421078A/de unknown
- 1961-07-20 FR FR868440A patent/FR1325M/fr active Active
- 1961-07-24 ES ES0269353A patent/ES269353A1/es not_active Expired
- 1961-07-25 DK DK304861AA patent/DK113854B/da unknown
- 1961-07-25 GB GB26864/61A patent/GB940540A/en not_active Expired
- 1961-07-26 BE BE606560A patent/BE606560A/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH421078A (de) | 1966-09-30 |
| FR1325M (fr) | 1962-05-21 |
| GB940540A (en) | 1963-10-30 |
| NL124473C (zh) | |
| US3176019A (en) | 1965-03-30 |
| DE1216866B (de) | 1966-05-18 |
| BE606560A (fr) | 1962-01-26 |
| DK113854B (da) | 1969-05-05 |
| ES269353A1 (es) | 1961-11-16 |