NI200600279A - Derivados de tetrahidroisoquinolilsulfonamidas, su preparación y su utilización en terapéutica - Google Patents
Derivados de tetrahidroisoquinolilsulfonamidas, su preparación y su utilización en terapéuticaInfo
- Publication number
- NI200600279A NI200600279A NI200600279A NI200600279A NI200600279A NI 200600279 A NI200600279 A NI 200600279A NI 200600279 A NI200600279 A NI 200600279A NI 200600279 A NI200600279 A NI 200600279A NI 200600279 A NI200600279 A NI 200600279A
- Authority
- NI
- Nicaragua
- Prior art keywords
- group
- alkyl
- optionally substituted
- hydrogen atom
- alkylidene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Psychiatry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Reproductive Health (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Psychology (AREA)
- Gynecology & Obstetrics (AREA)
- Anesthesiology (AREA)
- Otolaryngology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Compuesto que responde a la fórmula (I) en la que n puede tomar un valor de 1 a 6;-(C)n- representa un grupo alquilideno C1-6, opcionalmente sustituido con 1-4 sustituyentes; R1 representan un átomo de hidrógeno, un grupo alquilo C1-6, R2 representa un átomo de hidrógeno, un grupo alquilo C1-6 o cicloalquilo C3-6 opcionalmente sustituidos con 1 a 4 sustituyentes, B representa NR3R4, R3 y R4 representan, independientemente del otro, un grupo alquilo C1-6, un átomo de hidrógeno , o R3 y R4 representan juntos un grupo alquilideno C1-6, un grupo alquenilideno C2-8, un grupo alquilideno C1-3-O-alquilideno C1-3, o un grupo alquilideno C1-3-N(R5)-alquilideno C1-3, donde R5 representa un átomo de hidrógeno o un grupo alquilo C1-3 o alquilcarbonilo C1-6, pudiendo estos grupos alquilo C1-3 y alquilocarbonilo C1-6 estar sustituidos, o un aminociclo unido pon un carbono al grupo -NR1-(C)n-, tal como aziridina, azetidina, pirrolidina, piperidina o morfolino, estando los grupos R3, R4, así como el aminociclo opcionalmente sustituidos y el átomo de nitrógeno opcionalmente sustituido. Aplicación en terapéutica.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0405607A FR2870846B1 (fr) | 2004-05-25 | 2004-05-25 | Derives de tetrahydroisoquinolylsulfonamides, leur preparation et leur utilisation en therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NI200600279A true NI200600279A (es) | 2008-01-22 |
Family
ID=34944870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NI200600279A NI200600279A (es) | 2004-05-25 | 2006-11-23 | Derivados de tetrahidroisoquinolilsulfonamidas, su preparación y su utilización en terapéutica |
Country Status (41)
| Country | Link |
|---|---|
| US (3) | US7833999B2 (es) |
| EP (1) | EP1753725B1 (es) |
| JP (1) | JP4861979B2 (es) |
| KR (1) | KR101176675B1 (es) |
| CN (1) | CN1956962B (es) |
| AR (1) | AR050250A1 (es) |
| AU (1) | AU2005250197B2 (es) |
| BR (1) | BRPI0511581A (es) |
| CA (1) | CA2565293C (es) |
| CR (1) | CR8735A (es) |
| CY (1) | CY1114240T1 (es) |
| DK (1) | DK1753725T3 (es) |
| DO (1) | DOP2005000103A (es) |
| EA (1) | EA010234B1 (es) |
| EC (1) | ECSP067020A (es) |
| ES (1) | ES2407140T3 (es) |
| FR (1) | FR2870846B1 (es) |
| GT (1) | GT200500126A (es) |
| HK (1) | HK1106229A1 (es) |
| HN (1) | HN2005000239A (es) |
| HR (1) | HRP20130431T1 (es) |
| IL (1) | IL179021A (es) |
| JO (1) | JO2877B1 (es) |
| MA (1) | MA28720B1 (es) |
| MX (1) | MXPA06013629A (es) |
| MY (1) | MY148980A (es) |
| NI (1) | NI200600279A (es) |
| NO (1) | NO338104B1 (es) |
| NZ (1) | NZ551509A (es) |
| PA (1) | PA8634501A1 (es) |
| PE (1) | PE20060273A1 (es) |
| PL (1) | PL1753725T3 (es) |
| PT (1) | PT1753725E (es) |
| SI (1) | SI1753725T1 (es) |
| SV (1) | SV2006002126A (es) |
| TN (1) | TNSN06356A1 (es) |
| TW (1) | TWI360540B (es) |
| UA (1) | UA84771C2 (es) |
| UY (1) | UY28917A1 (es) |
| WO (1) | WO2005118547A1 (es) |
| ZA (1) | ZA200609820B (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2870846B1 (fr) * | 2004-05-25 | 2006-08-04 | Sanofi Synthelabo | Derives de tetrahydroisoquinolylsulfonamides, leur preparation et leur utilisation en therapeutique |
| EP1790646A1 (fr) * | 2005-11-24 | 2007-05-30 | Sanofi-Aventis | Derives de Isoquinoline et Benzo[h]Isoquinoline, leur preparation et leur utilisation en thérapeutique en tant qu'antagonistes du recepteur de l'histamine H3. |
| KR101571176B1 (ko) | 2007-11-13 | 2015-11-23 | 다이쇼 세이야꾸 가부시끼가이샤 | 페닐피라졸 유도체 |
| TW201039822A (en) | 2009-02-06 | 2010-11-16 | Taisho Pharmaceutical Co Ltd | Dihydroquinolinone derivatives |
| SG176645A1 (en) * | 2009-06-26 | 2012-01-30 | Sanofi Sa | Novel fumarate salts of a histamine h3 receptor antagonist |
| AR080374A1 (es) | 2010-03-05 | 2012-04-04 | Sanofi Aventis | Procedimiento para la preparcion de 2-(ciclohexilmetil)-n-(2-((2s)-1-metilpirrolidin-2-il) etil)- 1,2,3,4-tetrahidroisoquinolin-7- sulfonamida |
| KR20140100483A (ko) | 2011-12-08 | 2014-08-14 | 다이쇼 세이야꾸 가부시끼가이샤 | 페닐피롤 유도체 |
| JPWO2013100054A1 (ja) | 2011-12-27 | 2015-05-11 | 大正製薬株式会社 | フェニルトリアゾール誘導体 |
| EP2647377A1 (en) * | 2012-04-06 | 2013-10-09 | Sanofi | Use of an h3 receptor antagonist for the treatment of alzheimer's disease |
| WO2015032966A1 (en) * | 2013-09-09 | 2015-03-12 | Sanofi | An h3 receptor antagonist combined with a cholinesterase inhibitor for use in the treatment of alzheimer's disease |
| CN110642854A (zh) * | 2019-11-20 | 2020-01-03 | 成都克莱蒙医药科技有限公司 | 一种稠环化合物的多晶型、其组合物、制备方法及其应用 |
| EP4251148A1 (en) | 2020-11-27 | 2023-10-04 | Richter Gedeon Nyrt. | Histamine h3 receptor antagonists/inverse agonists for the treatment of autism spectrum disorder |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0702671A4 (en) | 1993-06-09 | 1996-06-19 | Smithkline Beecham Corp | BICYCLIC FIBRINOGEN ANTAGONISTS |
| GB9508622D0 (en) | 1995-04-28 | 1995-06-14 | Pfizer Ltd | Therapeutic agants |
| RU2182904C2 (ru) * | 1996-02-09 | 2002-05-27 | Джеймс Блэк Фаундейшн Лимитед | Сульфонамиды и способы их получения |
| AR015269A1 (es) | 1998-04-10 | 2001-04-18 | Japan Tobacco Inc | Compuesto amidinico y composicion farmaceutica, inhibidor de la coagulacion sanguinea e inhibidor del factor xa que lo comprenden |
| US6545055B1 (en) | 1999-05-24 | 2003-04-08 | Millennium Pharmaceuticals, Inc. | Inhibitors of factor Xa |
| JP4031363B2 (ja) | 2001-01-02 | 2008-01-09 | エフ．ホフマン−ラ ロシュ アーゲー | α−１Ａ／Ｂアドレナリン作動性受容体拮抗薬としてのキナゾロン誘導体 |
| JP2004532834A (ja) * | 2001-03-23 | 2004-10-28 | イーライ・リリー・アンド・カンパニー | ヒスタミンｈ３受容体アンタゴニストである非イミダゾール系アリールアルキルアミン化合物、その製造および治療的使用 |
| WO2003055848A2 (en) * | 2001-12-26 | 2003-07-10 | Bayer Healthcare Ag | Urea derivatives as vr1- antagonists |
| JP2003192660A (ja) * | 2001-12-26 | 2003-07-09 | Bayer Ag | 尿素誘導体 |
| WO2003076527A1 (fr) | 2002-03-08 | 2003-09-18 | Sakata Inx Corp. | Pigment traite, utilisation associee et compose de traitement de pigments |
| GB0206033D0 (en) | 2002-03-14 | 2002-04-24 | Pfizer Ltd | Compounds useful in therapy |
| EA011095B1 (ru) * | 2002-08-29 | 2008-12-30 | Бёрингер Ингельхайм Фармасьютиклз, Инк. | Производные 3-(сульфонамидоэтил)индола, предназначенные для использования в качестве миметиков глюкокортикоидов при лечении воспалительных, аллергических и пролиферативных заболеваний |
| NZ546365A (en) | 2003-10-08 | 2010-01-29 | Vertex Pharma | Modulators of ATP-binding cassette transporters containing cycloalkyl or pyranyl groups |
| WO2005040135A1 (ja) | 2003-10-24 | 2005-05-06 | Ono Pharmaceutical Co., Ltd. | 抗ストレス薬およびその医薬用途 |
| FR2870846B1 (fr) * | 2004-05-25 | 2006-08-04 | Sanofi Synthelabo | Derives de tetrahydroisoquinolylsulfonamides, leur preparation et leur utilisation en therapeutique |
| ES2257168B1 (es) | 2004-08-18 | 2007-06-01 | Laboratorios Del Dr Esteve, S.A. | Ligandos del receptor 5-ht7. |
| EP1630158A1 (en) | 2004-08-18 | 2006-03-01 | Laboratorios Del Dr. Esteve, S.A. | 5-HT7 receptor antagonists |
| US20080261999A1 (en) | 2005-03-04 | 2008-10-23 | Fionna Mitchell Martin | Azabicycloalkane Derivatives Useful as Nicotinic Acetylcholine Receptor Agonists |
| EP1790646A1 (fr) | 2005-11-24 | 2007-05-30 | Sanofi-Aventis | Derives de Isoquinoline et Benzo[h]Isoquinoline, leur preparation et leur utilisation en thérapeutique en tant qu'antagonistes du recepteur de l'histamine H3. |
-
2004
- 2004-05-25 FR FR0405607A patent/FR2870846B1/fr not_active Expired - Lifetime
-
2005
- 2005-05-23 AR ARP050102107A patent/AR050250A1/es not_active Application Discontinuation
- 2005-05-23 PE PE2005000566A patent/PE20060273A1/es not_active Application Discontinuation
- 2005-05-23 JO JO200571A patent/JO2877B1/en active
- 2005-05-23 HN HN2005000239A patent/HN2005000239A/es unknown
- 2005-05-24 CN CN200580016856.7A patent/CN1956962B/zh active Active
- 2005-05-24 EA EA200602176A patent/EA010234B1/ru not_active IP Right Cessation
- 2005-05-24 GT GT200500126A patent/GT200500126A/es unknown
- 2005-05-24 WO PCT/FR2005/001279 patent/WO2005118547A1/fr active Application Filing
- 2005-05-24 DK DK05772938.6T patent/DK1753725T3/da active
- 2005-05-24 TW TW094116907A patent/TWI360540B/zh not_active IP Right Cessation
- 2005-05-24 SV SV2005002126A patent/SV2006002126A/es active IP Right Grant
- 2005-05-24 ZA ZA200609820A patent/ZA200609820B/xx unknown
- 2005-05-24 MY MYPI20052337A patent/MY148980A/en unknown
- 2005-05-24 PT PT57729386T patent/PT1753725E/pt unknown
- 2005-05-24 CA CA2565293A patent/CA2565293C/fr not_active Expired - Fee Related
- 2005-05-24 BR BRPI0511581-7A patent/BRPI0511581A/pt not_active Application Discontinuation
- 2005-05-24 UY UY28917A patent/UY28917A1/es not_active Application Discontinuation
- 2005-05-24 PL PL05772938T patent/PL1753725T3/pl unknown
- 2005-05-24 UA UAA200613640A patent/UA84771C2/uk unknown
- 2005-05-24 KR KR1020067024780A patent/KR101176675B1/ko active IP Right Grant
- 2005-05-24 NZ NZ551509A patent/NZ551509A/en not_active IP Right Cessation
- 2005-05-24 SI SI200531708T patent/SI1753725T1/sl unknown
- 2005-05-24 ES ES05772938T patent/ES2407140T3/es active Active
- 2005-05-24 MX MXPA06013629A patent/MXPA06013629A/es active IP Right Grant
- 2005-05-24 EP EP05772938A patent/EP1753725B1/fr active Active
- 2005-05-24 AU AU2005250197A patent/AU2005250197B2/en not_active Ceased
- 2005-05-24 JP JP2007514007A patent/JP4861979B2/ja active Active
- 2005-05-25 DO DO2005000103A patent/DOP2005000103A/es unknown
- 2005-05-25 PA PA20058634501A patent/PA8634501A1/es unknown
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2006
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