MXPA05005286A - Composiciones para el tratamiento y/o prevencion de enfermedades caracterizadas por la presencia de iones metalicos. - Google Patents
Composiciones para el tratamiento y/o prevencion de enfermedades caracterizadas por la presencia de iones metalicos.Info
- Publication number
- MXPA05005286A MXPA05005286A MXPA05005286A MXPA05005286A MXPA05005286A MX PA05005286 A MXPA05005286 A MX PA05005286A MX PA05005286 A MXPA05005286 A MX PA05005286A MX PA05005286 A MXPA05005286 A MX PA05005286A MX PA05005286 A MXPA05005286 A MX PA05005286A
- Authority
- MX
- Mexico
- Prior art keywords
- composition
- certain
- blood
- brain
- organosilicon compound
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 6
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 229910021645 metal ion Inorganic materials 0.000 title abstract 2
- 150000003961 organosilicon compounds Chemical class 0.000 abstract 4
- 229910052782 aluminium Inorganic materials 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 230000008499 blood brain barrier function Effects 0.000 abstract 2
- 210000001218 blood-brain barrier Anatomy 0.000 abstract 2
- 210000004556 brain Anatomy 0.000 abstract 2
- -1 cyclic organosilane Chemical class 0.000 abstract 2
- SCPYDCQAZCOKTP-UHFFFAOYSA-N silanol Chemical compound [SiH3]O SCPYDCQAZCOKTP-UHFFFAOYSA-N 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 150000002500 ions Chemical class 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 230000004962 physiological condition Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 210000002784 stomach Anatomy 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/695—Silicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/04—Chelating agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Toxicology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42720302P | 2002-11-18 | 2002-11-18 | |
| US42710402P | 2002-11-18 | 2002-11-18 | |
| US42710502P | 2002-11-18 | 2002-11-18 | |
| US42720102P | 2002-11-18 | 2002-11-18 | |
| US45634503P | 2003-03-20 | 2003-03-20 | |
| US0336749 | 2003-11-17 | ||
| PCT/US2003/037037 WO2004045552A2 (en) | 2002-11-18 | 2003-11-18 | Compositions for treating and/or preventing diseases characterized by the presence of metal ions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA05005286A true MXPA05005286A (es) | 2006-02-22 |
Family
ID=34382290
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA05005286A MXPA05005286A (es) | 2002-11-18 | 2003-11-18 | Composiciones para el tratamiento y/o prevencion de enfermedades caracterizadas por la presencia de iones metalicos. |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JP2006526567A (ja) |
| AU (1) | AU2003298673A1 (ja) |
| CA (1) | CA2506231A1 (ja) |
| MX (1) | MXPA05005286A (ja) |
| WO (1) | WO2004045552A2 (ja) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7595308B2 (en) | 2002-11-18 | 2009-09-29 | Grenpharma Llc | Compositions for treating and/or preventing diseases characterized by the presence of metal ions |
| WO2006028491A1 (en) * | 2004-02-13 | 2006-03-16 | University Of Florida | Biocides based on silanol terminated silanes and siloxanes |
| US7960576B2 (en) | 2004-08-13 | 2011-06-14 | Momentive Performance Materials Inc. | Diol-derived organofunctional silane and compositions containing same |
| US7928258B2 (en) | 2004-08-20 | 2011-04-19 | Momentive Performance Materials Inc. | Cyclic diol-derived blocked mercaptofunctional silane compositions |
| WO2006047477A1 (en) * | 2004-10-22 | 2006-05-04 | Grenpharama Llc | Compositions for treating and/or preventing diseases characterized by the presence of the metal ions |
| US7504456B2 (en) | 2006-02-21 | 2009-03-17 | Momentive Performance Materials Inc. | Rubber composition containing organofunctional silane |
| US7510670B2 (en) | 2006-02-21 | 2009-03-31 | Momentive Performance Materials Inc. | Free flowing filler composition based on organofunctional silane |
| US7919650B2 (en) | 2006-02-21 | 2011-04-05 | Momentive Performance Materials Inc. | Organofunctional silanes and their mixtures |
| US7718819B2 (en) | 2006-02-21 | 2010-05-18 | Momentive Performance Materials Inc. | Process for making organofunctional silanes and mixtures thereof |
| US8097744B2 (en) | 2006-08-14 | 2012-01-17 | Momentive Performance Materials Inc. | Free flowing filler composition comprising mercapto-functional silane |
| US8008519B2 (en) | 2006-08-14 | 2011-08-30 | Momentive Performance Materials Inc. | Process for making mercapto-functional silane |
| US8026108B1 (en) * | 2006-10-19 | 2011-09-27 | The University Of Central Florida Research Foundation, Inc. | Detection of biotargets using bioreceptor functionalized nanoparticles |
| US7816435B2 (en) | 2007-10-31 | 2010-10-19 | Momentive Performance Materials Inc. | Halo-functional silane, process for its preparation, rubber composition containing same and articles manufactured therefrom |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4039666A (en) * | 1975-12-15 | 1977-08-02 | Dow Corning Corporation | Anticonvulsant phenylsilanes |
| US5384312A (en) * | 1987-05-08 | 1995-01-24 | Merrell Dow Pharmaceuticals Inc. | Substituted silyl alkylene amines |
| JPH06509103A (ja) * | 1991-07-15 | 1994-10-13 | アルベマール・コーポレーシヨン | 外傷性損傷の予防および重症度の減少 |
| US5523295A (en) * | 1994-07-06 | 1996-06-04 | Brandeis University | Method for treating and preventing alzheimer's disease |
| FR2725208B1 (fr) * | 1994-09-30 | 1996-11-29 | Exsymol Sa | Procede de preparation de composes de silicium biologiquement actifs sous forme concentree |
| US5854215A (en) * | 1995-03-14 | 1998-12-29 | Praecis Pharmaceuticals Incorporated | Modulators of β-amyloid peptide aggregation |
| JPH10101569A (ja) * | 1996-10-01 | 1998-04-21 | Eisai Co Ltd | 制酸剤 |
| US5859277A (en) * | 1997-06-25 | 1999-01-12 | Wisconsin Alumni Research Foundation | Silicon-containing solid support linker |
-
2003
- 2003-11-18 CA CA002506231A patent/CA2506231A1/en not_active Abandoned
- 2003-11-18 MX MXPA05005286A patent/MXPA05005286A/es not_active Application Discontinuation
- 2003-11-18 AU AU2003298673A patent/AU2003298673A1/en not_active Abandoned
- 2003-11-18 JP JP2004570636A patent/JP2006526567A/ja active Pending
- 2003-11-18 WO PCT/US2003/037037 patent/WO2004045552A2/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| CA2506231A1 (en) | 2004-06-03 |
| WO2004045552A3 (en) | 2005-08-18 |
| JP2006526567A (ja) | 2006-11-24 |
| WO2004045552A2 (en) | 2004-06-03 |
| AU2003298673A1 (en) | 2004-06-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |