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MXPA03011926A - Uso de copolimero de poli-glu, tyr y celulas tratadas con el mismo, para terapia neuroprotectora. - Google Patents

Uso de copolimero de poli-glu, tyr y celulas tratadas con el mismo, para terapia neuroprotectora.

Info

Publication number
MXPA03011926A
MXPA03011926A MXPA03011926A MXPA03011926A MXPA03011926A MX PA03011926 A MXPA03011926 A MX PA03011926A MX PA03011926 A MXPA03011926 A MX PA03011926A MX PA03011926 A MXPA03011926 A MX PA03011926A MX PA03011926 A MXPA03011926 A MX PA03011926A
Authority
MX
Mexico
Prior art keywords
tyr
glu
copolimero
neuroprotecting
poli
Prior art date
Application number
MXPA03011926A
Other languages
English (en)
Inventor
Yoles Ester
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Publication of MXPA03011926A publication Critical patent/MXPA03011926A/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0007—Nervous system antigens; Prions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/414—Nervous system antigens
    • A—HUMAN NECESSITIES
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A—HUMAN NECESSITIES
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/47—Brain; Nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Psychology (AREA)
  • Addiction (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)

Abstract

Se proveen metodos y composiciones para prevenir o inhibir la degeneracion neuronal, o para promover la regeneracion nerviosa en el sistema nervioso central, CNS, o el sistema nervioso periferico, PNS, o para proteger a las celulas del CNS de la toxicidad del glutamato, que comprenden un agente seleccionado del grupo que consiste de poli-Glu,Tyr y celulas T que han sido activadas con poli-Glu,Tyr.
MXPA03011926A 2001-06-28 2002-06-27 Uso de copolimero de poli-glu, tyr y celulas tratadas con el mismo, para terapia neuroprotectora. MXPA03011926A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/893,344 US6835711B2 (en) 2001-06-28 2001-06-28 Use of poly-Glu,Tyr for neuroprotective therapy
PCT/IL2002/000517 WO2003002140A1 (en) 2001-06-28 2002-06-27 Use of poly-glu, tyr and t cells treated therewith for neuroprotection therapy

Publications (1)

Publication Number Publication Date
MXPA03011926A true MXPA03011926A (es) 2004-03-26

Family

ID=25401407

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03011926A MXPA03011926A (es) 2001-06-28 2002-06-27 Uso de copolimero de poli-glu, tyr y celulas tratadas con el mismo, para terapia neuroprotectora.

Country Status (16)

Country Link
US (1) US6835711B2 (es)
EP (1) EP1406650B1 (es)
JP (1) JP4434729B2 (es)
KR (1) KR20040032825A (es)
CN (1) CN1326560C (es)
AT (1) ATE412419T1 (es)
AU (1) AU2002345323B2 (es)
CA (1) CA2451521C (es)
DE (1) DE60229639D1 (es)
DK (1) DK1406650T3 (es)
ES (1) ES2315371T3 (es)
HK (1) HK1064951A1 (es)
IL (1) IL159535A0 (es)
MX (1) MXPA03011926A (es)
NZ (1) NZ530261A (es)
WO (1) WO2003002140A1 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7399740B2 (en) * 2001-06-28 2008-07-15 Yeda Research And Development Co. Ltd. Poly-Glu,Tyr for neuroprotective therapy
WO2004060266A2 (en) * 2003-01-07 2004-07-22 Yeda Research And Development Co. Ltd. Eye-drop vaccine containing copolymer poly-ye for therapeutic immunization
CA2469092C (en) * 2001-12-06 2013-02-19 Yeda Research And Development Co. Ltd Copolymer 1 vaccine and methods for treatment of amyotrophic lateral sclerosis (als)
JP4609855B2 (ja) * 2003-06-16 2011-01-12 国立大学法人九州大学 ヒト由来免疫担当細胞の製造方法
US9592258B2 (en) 2003-06-27 2017-03-14 DePuy Synthes Products, Inc. Treatment of neurological injury by administration of human umbilical cord tissue-derived cells
PT1701730E (pt) * 2003-12-09 2013-11-27 Yeda Res & Dev Método e vacina compreendendo copolímero 1 para tratamento de distúrbios psiquiátricos
WO2005055920A2 (en) * 2003-12-09 2005-06-23 Yeda Research And Development Co. Ltd. Compositions and methods for treatment of psychiatric disorders
WO2006057003A2 (en) * 2004-11-29 2006-06-01 Yeda Research And Development Co. Ltd. Induction of neurogenesis and stem cell therapy in combination with copolymer 1
US9220813B2 (en) * 2005-04-18 2015-12-29 Holy Cross Hospital, Inc. Cell therapy for limiting overzealous inflammatory reactions in tissue healing
EP2234633A1 (en) * 2007-12-21 2010-10-06 Ben Gurion University Of The Negev Research And Development Authority A method of treating neurodegenerative diseases
US9820747B2 (en) * 2008-04-04 2017-11-21 The Cleveland Clinic Foundation Use of epineural sheath grafts for neural regeneration and protection
PT2379087E (pt) * 2008-12-19 2014-12-02 Depuy Synthes Products Llc Células derivadas do tecido do cordão umbilical para o tratamento da dor neuropática e espasticidade
WO2010111663A1 (en) 2009-03-26 2010-09-30 Ethicon, Inc. Human umbilical cord tissue cells as therapy for alzheimer' s disease
US20120171172A1 (en) * 2009-09-04 2012-07-05 Maria Siemionow Methods Of Engineering Neural Tissue
USRE49251E1 (en) 2010-01-04 2022-10-18 Mapi Pharma Ltd. Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
US8377885B2 (en) 2010-01-04 2013-02-19 Mapi Pharma Ltd. Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
CA2784394C (en) 2010-01-04 2016-12-13 Mapi Pharma Limited Depot systems comprising glatiramer or a pharmacologically acceptable salt thereof
EP2699317B1 (en) 2011-04-21 2016-08-10 Mapi Pharma Limited Random pentapolymer for treatment of autoimmune diseases
US12097292B2 (en) 2016-08-28 2024-09-24 Mapi Pharma Ltd. Process for preparing microparticles containing glatiramer acetate
WO2018178973A1 (en) 2017-03-26 2018-10-04 Mapi Pharma Ltd. Glatiramer depot systems for treating progressive forms of multiple sclerosis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999034827A1 (en) 1998-07-21 1999-07-15 Yeda Research And Development Co. Ltd. Activated t-cells and their uses

Also Published As

Publication number Publication date
KR20040032825A (ko) 2004-04-17
HK1064951A1 (en) 2005-02-08
US20030003082A1 (en) 2003-01-02
CN1547482A (zh) 2004-11-17
JP2005502616A (ja) 2005-01-27
IL159535A0 (en) 2004-06-01
DK1406650T3 (da) 2009-03-02
ATE412419T1 (de) 2008-11-15
ES2315371T3 (es) 2009-04-01
JP4434729B2 (ja) 2010-03-17
WO2003002140A1 (en) 2003-01-09
CA2451521C (en) 2011-05-17
EP1406650A1 (en) 2004-04-14
CN1326560C (zh) 2007-07-18
NZ530261A (en) 2006-06-30
DE60229639D1 (de) 2008-12-11
AU2002345323B2 (en) 2006-12-21
CA2451521A1 (en) 2003-01-09
EP1406650B1 (en) 2008-10-29
US6835711B2 (en) 2004-12-28

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