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MXPA03011006A - Compuestos de cicloalquil urea benzo-fusionados 1,4-disustituidos. - Google Patents

Compuestos de cicloalquil urea benzo-fusionados 1,4-disustituidos.

Info

Publication number
MXPA03011006A
MXPA03011006A MXPA03011006A MXPA03011006A MXPA03011006A MX PA03011006 A MXPA03011006 A MX PA03011006A MX PA03011006 A MXPA03011006 A MX PA03011006A MX PA03011006 A MXPA03011006 A MX PA03011006A MX PA03011006 A MXPA03011006 A MX PA03011006A
Authority
MX
Mexico
Prior art keywords
urea compounds
fused cycloalkyl
disubstituted benzo
cycloalkyl urea
disubstituted
Prior art date
Application number
MXPA03011006A
Other languages
English (en)
Inventor
F Cirillo Pier
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of MXPA03011006A publication Critical patent/MXPA03011006A/es

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
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    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
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Abstract

La presente invencion describe compuestos de formula (I), los cuales son activos como agentes antiinflamatorios. Tambien describe metodos para usar y para elaborar tales compuestos. (ver formula).
MXPA03011006A 2001-06-05 2002-05-24 Compuestos de cicloalquil urea benzo-fusionados 1,4-disustituidos. MXPA03011006A (es)

Applications Claiming Priority (2)

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US29590901P 2001-06-05 2001-06-05
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JP4424983B2 (ja) 2010-03-03
CA2446193C (en) 2011-11-01
EP1414810A2 (en) 2004-05-06
US20030100608A1 (en) 2003-05-29
WO2002098869A2 (en) 2002-12-12
DE60214392D1 (de) 2006-10-12
EP1414810B1 (en) 2006-08-30
ATE338035T1 (de) 2006-09-15
DE60214392T2 (de) 2008-01-17
CA2446193A1 (en) 2002-12-12
ES2269709T3 (es) 2007-04-01
JP2004534787A (ja) 2004-11-18
WO2002098869A3 (en) 2004-02-26
US6720321B2 (en) 2004-04-13

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