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MXPA03007839A - Factor neurotrofico ciliar modificaco con inmunogenicidad reducida. - Google Patents

Factor neurotrofico ciliar modificaco con inmunogenicidad reducida.

Info

Publication number
MXPA03007839A
MXPA03007839A MXPA03007839A MXPA03007839A MXPA03007839A MX PA03007839 A MXPA03007839 A MX PA03007839A MX PA03007839 A MXPA03007839 A MX PA03007839A MX PA03007839 A MXPA03007839 A MX PA03007839A MX PA03007839 A MXPA03007839 A MX PA03007839A
Authority
MX
Mexico
Prior art keywords
cntf
neurotrophic factor
reduced immunogenicity
ciliary neurotrophic
modified ciliary
Prior art date
Application number
MXPA03007839A
Other languages
English (en)
Inventor
Graham Carter
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of MXPA03007839A publication Critical patent/MXPA03007839A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/185Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
MXPA03007839A 2001-03-02 2002-02-27 Factor neurotrofico ciliar modificaco con inmunogenicidad reducida. MXPA03007839A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01105089 2001-03-02
PCT/EP2002/002084 WO2002070698A2 (en) 2001-03-02 2002-02-27 Modified ciliary neurotrophic factor (cntf) with reduced immunogenicity

Publications (1)

Publication Number Publication Date
MXPA03007839A true MXPA03007839A (es) 2003-12-08

Family

ID=8176647

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03007839A MXPA03007839A (es) 2001-03-02 2002-02-27 Factor neurotrofico ciliar modificaco con inmunogenicidad reducida.

Country Status (13)

Country Link
US (1) US20040087503A1 (es)
EP (1) EP1379655A2 (es)
JP (1) JP2004529629A (es)
KR (1) KR20030081480A (es)
CN (1) CN1494593A (es)
BR (1) BR0207705A (es)
CA (1) CA2439682A1 (es)
HU (1) HUP0303310A2 (es)
MX (1) MXPA03007839A (es)
PL (1) PL362704A1 (es)
RU (1) RU2003129069A (es)
WO (1) WO2002070698A2 (es)
ZA (1) ZA200307678B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005014641A2 (en) * 2003-07-09 2005-02-17 Xencor, Inc. Ciliary neurotrophic factor variants
US20050069987A1 (en) * 2003-09-30 2005-03-31 Daly Thomas J. Modified ciliary neurotrophic factor polypeptides with reduced antigenicity
US8592374B2 (en) 2007-03-16 2013-11-26 Research Foundation For Mental Hygiene, Inc. Neurotrophic peptides
EP2009103A1 (en) 2007-03-16 2008-12-31 Ebewe Pharma Ges.m.b.H. Nfg. KG Neurotrophic peptides
US20090010966A1 (en) * 2007-06-21 2009-01-08 Angelica Therapeutics, Inc. Modified diphtheria toxins
US8470314B2 (en) * 2008-02-29 2013-06-25 Angelica Therapeutics, Inc. Modified toxins
DE102011104822A1 (de) 2011-06-18 2012-12-20 Christian-Albrechts-Universität Zu Kiel Ciliary-Neutrophic-Factor-Varianten
WO2014150600A2 (en) 2013-03-15 2014-09-25 Angelica Therapeutics, Inc. Modified toxins
JP6840668B2 (ja) * 2014-11-14 2021-03-10 ディ.イー.ショー リサーチ, エルエルシーD.E.Shaw Research, Llc 結合された粒子間の相互作用の抑制
AU2017370653B2 (en) * 2016-12-06 2022-07-21 The Board Of Trustees Of The Leland Stanford Junior University Ciliary neurotrophic factor receptor ligand-binding agents and methods of using the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5593857A (en) * 1991-08-23 1997-01-14 Scios Inc. Production of homogeneous truncated CNTF
JPH07503128A (ja) * 1991-11-11 1995-04-06 フィディーア・ソシエタ・ペル・アチオニ ヒト毛様体ニューロン親和性因子の先端欠失型および突然変異タンパク質型の合成と精製
WO1995018150A1 (fr) * 1993-12-29 1995-07-06 Sumitomo Pharmaceuticals Company, Limited Nouveau facteur neurotrophique ciliaire humain
IT1288388B1 (it) * 1996-11-19 1998-09-22 Angeletti P Ist Richerche Bio Uso di sostanze che attivano il recettore del cntf ( fattore neurotrofico ciliare) per la preparazione di farmaci per la terapia
JP2003507393A (ja) * 1999-08-13 2003-02-25 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 改変された毛様体神経栄養因子、それらを作製する方法およびそれらの使用方法

Also Published As

Publication number Publication date
CA2439682A1 (en) 2002-09-12
US20040087503A1 (en) 2004-05-06
KR20030081480A (ko) 2003-10-17
PL362704A1 (en) 2004-11-02
HUP0303310A2 (hu) 2003-12-29
RU2003129069A (ru) 2005-04-20
JP2004529629A (ja) 2004-09-30
CN1494593A (zh) 2004-05-05
EP1379655A2 (en) 2004-01-14
WO2002070698A2 (en) 2002-09-12
ZA200307678B (en) 2004-08-31
BR0207705A (pt) 2004-03-23
WO2002070698A3 (en) 2003-11-20

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