MXPA03002557A - Potassium channel interactors and uses therefor. - Google Patents
Potassium channel interactors and uses therefor.Info
- Publication number
- MXPA03002557A MXPA03002557A MXPA03002557A MXPA03002557A MXPA03002557A MX PA03002557 A MXPA03002557 A MX PA03002557A MX PA03002557 A MXPA03002557 A MX PA03002557A MX PA03002557 A MXPA03002557 A MX PA03002557A MX PA03002557 A MXPA03002557 A MX PA03002557A
- Authority
- MX
- Mexico
- Prior art keywords
- pcip
- nucleic acid
- acid molecules
- potassium channel
- proteins
- Prior art date
Links
- 102000004257 Potassium Channel Human genes 0.000 title abstract 3
- 108020001213 potassium channel Proteins 0.000 title abstract 3
- 101100025911 Mus musculus Ncoa3 gene Proteins 0.000 abstract 4
- 102000039446 nucleic acids Human genes 0.000 abstract 4
- 108020004707 nucleic acids Proteins 0.000 abstract 4
- 150000007523 nucleic acids Chemical class 0.000 abstract 4
- 239000013604 expression vector Substances 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 230000000692 anti-sense effect Effects 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 238000003259 recombinant expression Methods 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Heart & Thoracic Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pain & Pain Management (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Cardiology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
The invention provides isolated nucleic acids molecules, designated PCIP nucleic acid molecules, which encode proteins that bind potassium channels and modulate potassium channel mediated activities. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing PCIP nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a PCIP gene has been introduced or disrupted. The invention still further provides isolated PCIP proteins, fusion proteins, antigenic peptides and anti-PCIP antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/670,756 US7078481B1 (en) | 1998-11-20 | 2000-09-27 | Potassium channel interactors and uses therefor |
| US09/703,094 US7556938B1 (en) | 1998-11-20 | 2000-10-31 | Nucleic acids encoding potassium channel interactors |
| PCT/US2001/030463 WO2002026984A2 (en) | 2000-09-27 | 2001-09-27 | Potassium channel interactors and uses therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA03002557A true MXPA03002557A (en) | 2004-09-10 |
Family
ID=27100393
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA03002557A MXPA03002557A (en) | 2000-09-27 | 2001-09-27 | Potassium channel interactors and uses therefor. |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1322759A2 (en) |
| JP (1) | JP2004525610A (en) |
| KR (1) | KR20030074604A (en) |
| CN (1) | CN1498271A (en) |
| AU (1) | AU2001296393A1 (en) |
| BR (1) | BR0114383A (en) |
| CA (1) | CA2420960A1 (en) |
| CZ (1) | CZ20031154A3 (en) |
| EA (1) | EA200300420A1 (en) |
| IL (1) | IL154962A0 (en) |
| MX (1) | MXPA03002557A (en) |
| NO (1) | NO20031369L (en) |
| WO (1) | WO2002026984A2 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7067312B1 (en) | 2001-09-19 | 2006-06-27 | Myriad Genetics, Inc. | PN7718 nucleic acids and use thereof |
| WO2004041193A2 (en) * | 2002-11-01 | 2004-05-21 | Decode Genetics Ehf. | HUMAN TYPE II DIABETES GENE-Kv CHANNEL-INTERACTING PROTEIN (KChIP1) LOCATED ON CHROMOSOME 5 |
| JP2012507273A (en) * | 2008-11-06 | 2012-03-29 | ビーエーエスエフ ソシエタス・ヨーロピア | Insecticide screening assay |
| CN105483276B (en) * | 2016-02-01 | 2019-06-11 | 成都望路医药技术有限公司 | The application of KCNIP4 gene and its expression product in rectal adenocarcinoma diagnosis and treatment |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4758997A (en) * | 1996-10-17 | 1998-05-11 | Nps Pharmaceuticals, Inc. | Potassium channel blocking compounds and their use |
| US6117989A (en) * | 1998-03-26 | 2000-09-12 | Incyte Pharmaceuticals, Inc. | Human calcium-binding proteins |
| JP2002530104A (en) * | 1998-11-20 | 2002-09-17 | ミレニアム ファーマスーティカルズ インク | Potassium channel interactors and uses thereof |
| AU5151100A (en) * | 1999-05-19 | 2000-12-05 | Incyte Genomics, Inc. | Extracellular signaling molecules |
| WO2001053312A1 (en) * | 1999-12-23 | 2001-07-26 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
-
2001
- 2001-09-27 CN CNA018191681A patent/CN1498271A/en active Pending
- 2001-09-27 MX MXPA03002557A patent/MXPA03002557A/en unknown
- 2001-09-27 EA EA200300420A patent/EA200300420A1/en unknown
- 2001-09-27 KR KR10-2003-7004460A patent/KR20030074604A/en not_active Application Discontinuation
- 2001-09-27 CZ CZ20031154A patent/CZ20031154A3/en unknown
- 2001-09-27 CA CA002420960A patent/CA2420960A1/en not_active Abandoned
- 2001-09-27 AU AU2001296393A patent/AU2001296393A1/en not_active Abandoned
- 2001-09-27 EP EP01977260A patent/EP1322759A2/en not_active Withdrawn
- 2001-09-27 WO PCT/US2001/030463 patent/WO2002026984A2/en not_active Application Discontinuation
- 2001-09-27 BR BR0114383-2A patent/BR0114383A/en not_active IP Right Cessation
- 2001-09-27 IL IL15496201A patent/IL154962A0/en unknown
- 2001-09-27 JP JP2002530747A patent/JP2004525610A/en active Pending
-
2003
- 2003-03-26 NO NO20031369A patent/NO20031369L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20030074604A (en) | 2003-09-19 |
| CZ20031154A3 (en) | 2003-09-17 |
| NO20031369L (en) | 2003-05-22 |
| WO2002026984A3 (en) | 2003-03-13 |
| AU2001296393A1 (en) | 2002-04-08 |
| BR0114383A (en) | 2005-04-12 |
| EA200300420A1 (en) | 2004-04-29 |
| WO2002026984A2 (en) | 2002-04-04 |
| JP2004525610A (en) | 2004-08-26 |
| NO20031369D0 (en) | 2003-03-26 |
| IL154962A0 (en) | 2003-10-31 |
| CA2420960A1 (en) | 2002-04-04 |
| CN1498271A (en) | 2004-05-19 |
| EP1322759A2 (en) | 2003-07-02 |
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