MXPA03000207A - Formulacion liposomica de propionato de clobetasol. - Google Patents
Formulacion liposomica de propionato de clobetasol.Info
- Publication number
- MXPA03000207A MXPA03000207A MXPA03000207A MXPA03000207A MXPA03000207A MX PA03000207 A MXPA03000207 A MX PA03000207A MX PA03000207 A MXPA03000207 A MX PA03000207A MX PA03000207 A MXPA03000207 A MX PA03000207A MX PA03000207 A MXPA03000207 A MX PA03000207A
- Authority
- MX
- Mexico
- Prior art keywords
- clobetasol propionate
- formulation
- active substance
- liposomes
- liposomic
- Prior art date
Links
- 229960004703 clobetasol propionate Drugs 0.000 title abstract 3
- CBGUOGMQLZIXBE-XGQKBEPLSA-N clobetasol propionate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CCl)(OC(=O)CC)[C@@]1(C)C[C@@H]2O CBGUOGMQLZIXBE-XGQKBEPLSA-N 0.000 title abstract 3
- 238000009472 formulation Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000013543 active substance Substances 0.000 abstract 2
- 239000002502 liposome Substances 0.000 abstract 2
- 206010012438 Dermatitis atopic Diseases 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 201000008937 atopic dermatitis Diseases 0.000 abstract 1
- 230000002349 favourable effect Effects 0.000 abstract 1
- 235000015110 jellies Nutrition 0.000 abstract 1
- 239000008274 jelly Substances 0.000 abstract 1
- 208000017520 skin disease Diseases 0.000 abstract 1
- 210000000434 stratum corneum Anatomy 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/14—Liposomes; Vesicles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Birds (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invencion se relaciona con una formulacion liposomica de propionato de clobetasol para uso topico para el tratamiento de enfermedades de la piel como dermatitis atopica y psoriasis con excelente aspecto organoleptico, muy buen efecto terapeutico y favorable distribucion en el estrato corneo. Los liposomas incluyen el propionato de clobetasol como principio activo en bajas dosis. Estos liposomas son preferiblemente vesiculas estables y multilamelares con un tamano medio entre 2000 - 5000 nm. La cantidad de principio activo es preferiblemente entre 0.02 y 0.025 %. La forma farmaceutica del producto es preferiblemente jalea.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CU20000171A CU23175A1 (es) | 2000-07-17 | 2000-07-17 | Formulacion liposomica de propionato de clobetasol |
PCT/CU2001/000005 WO2002007702A2 (es) | 2000-07-17 | 2001-07-17 | Formulación liposómica de propionato de clobetasol |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA03000207A true MXPA03000207A (es) | 2004-09-13 |
Family
ID=40134847
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA03000207A MXPA03000207A (es) | 2000-07-17 | 2001-07-17 | Formulacion liposomica de propionato de clobetasol. |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP1360958B1 (es) |
CN (1) | CN100346773C (es) |
AT (1) | ATE339188T1 (es) |
AU (2) | AU7625401A (es) |
BR (1) | BR0112553A (es) |
CA (1) | CA2416731C (es) |
CU (1) | CU23175A1 (es) |
DE (1) | DE60123132T2 (es) |
DK (1) | DK1360958T3 (es) |
ES (1) | ES2272508T3 (es) |
MX (1) | MXPA03000207A (es) |
WO (1) | WO2002007702A2 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7291626B1 (en) | 1998-04-09 | 2007-11-06 | John Hopkins University School Of Medicine | Inhibitors of hedgehog signaling pathways, compositions and uses related thereto |
IL149069A0 (en) | 1999-10-13 | 2002-11-10 | Univ Johns Hopkins Med | Regulators of the hedgehog pathway, compositions and uses related thereto |
CA2452152A1 (en) | 2001-07-02 | 2002-10-10 | Sinan Tas | Use of cyclopamine in the treatment of psoriasis |
DE60113733T2 (de) * | 2001-07-02 | 2006-06-29 | Tas, Sinan | Verwendung von cyclopamine, zur behandlung des basalzellkarzinoms und anderer tumoren |
US20180235882A1 (en) | 2015-09-02 | 2018-08-23 | Cadila Healthcare Limited | Topical compositions comprising corticosteroids |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1523965A (en) * | 1976-03-19 | 1978-09-06 | Ici Ltd | Pharmaceutical compositions containing steroids |
US5192528A (en) * | 1985-05-22 | 1993-03-09 | Liposome Technology, Inc. | Corticosteroid inhalation treatment method |
AU661754B2 (en) * | 1992-02-12 | 1995-08-03 | Janssen - Cilag - S.p.a. | Liposomal itraconazole formulations |
-
2000
- 2000-07-17 CU CU20000171A patent/CU23175A1/es not_active IP Right Cessation
-
2001
- 2001-07-17 EP EP01953764A patent/EP1360958B1/en not_active Expired - Lifetime
- 2001-07-17 DK DK01953764T patent/DK1360958T3/da active
- 2001-07-17 ES ES01953764T patent/ES2272508T3/es not_active Expired - Lifetime
- 2001-07-17 BR BR0112553-2A patent/BR0112553A/pt not_active Application Discontinuation
- 2001-07-17 AU AU7625401A patent/AU7625401A/xx active Pending
- 2001-07-17 CN CNB018128955A patent/CN100346773C/zh not_active Expired - Fee Related
- 2001-07-17 CA CA002416731A patent/CA2416731C/en not_active Expired - Fee Related
- 2001-07-17 WO PCT/CU2001/000005 patent/WO2002007702A2/es active IP Right Grant
- 2001-07-17 DE DE60123132T patent/DE60123132T2/de not_active Expired - Lifetime
- 2001-07-17 MX MXPA03000207A patent/MXPA03000207A/es active IP Right Grant
- 2001-07-17 AU AU2001276254A patent/AU2001276254B2/en not_active Ceased
- 2001-07-17 AT AT01953764T patent/ATE339188T1/de active
Also Published As
Publication number | Publication date |
---|---|
WO2002007702A3 (es) | 2003-07-31 |
AU7625401A (en) | 2002-02-05 |
HK1071070A1 (zh) | 2005-07-08 |
DE60123132T2 (de) | 2007-04-12 |
ATE339188T1 (de) | 2006-10-15 |
CU23175A1 (es) | 2006-09-22 |
CA2416731C (en) | 2009-12-15 |
CN1547465A (zh) | 2004-11-17 |
EP1360958A2 (en) | 2003-11-12 |
WO2002007702A2 (es) | 2002-01-31 |
EP1360958B1 (en) | 2006-09-13 |
CA2416731A1 (en) | 2003-01-16 |
BR0112553A (pt) | 2003-06-24 |
DE60123132D1 (de) | 2006-10-26 |
ES2272508T3 (es) | 2007-05-01 |
CN100346773C (zh) | 2007-11-07 |
DK1360958T3 (da) | 2007-01-29 |
AU2001276254B2 (en) | 2006-07-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |