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MXPA01011981A - Emulsion vehicle for poorly soluble drugs. - Google Patents

Emulsion vehicle for poorly soluble drugs.

Info

Publication number
MXPA01011981A
MXPA01011981A MXPA01011981A MXPA01011981A MXPA01011981A MX PA01011981 A MXPA01011981 A MX PA01011981A MX PA01011981 A MXPA01011981 A MX PA01011981A MX PA01011981 A MXPA01011981 A MX PA01011981A MX PA01011981 A MXPA01011981 A MX PA01011981A
Authority
MX
Mexico
Prior art keywords
poorly soluble
soluble drugs
emulsion vehicle
emulsion
vehicle
Prior art date
Application number
MXPA01011981A
Other languages
Spanish (es)
Inventor
Karel J Lambert
Original Assignee
Sonus Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/317,499 external-priority patent/US6660286B1/en
Application filed by Sonus Pharma Inc filed Critical Sonus Pharma Inc
Publication of MXPA01011981A publication Critical patent/MXPA01011981A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MXPA01011981A 1999-05-24 2000-05-17 Emulsion vehicle for poorly soluble drugs. MXPA01011981A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US31749599A 1999-05-24 1999-05-24
US09/317,499 US6660286B1 (en) 1997-01-07 1999-05-24 Emulsion vehicle for poorly soluble drugs
US15612899P 1999-09-27 1999-09-27
PCT/US2000/013572 WO2000071163A1 (en) 1999-05-24 2000-05-17 Emulsion vehicle for poorly soluble drugs

Publications (1)

Publication Number Publication Date
MXPA01011981A true MXPA01011981A (en) 2003-09-04

Family

ID=27387807

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA01011981A MXPA01011981A (en) 1999-05-24 2000-05-17 Emulsion vehicle for poorly soluble drugs.

Country Status (9)

Country Link
EP (1) EP1185301A1 (en)
JP (1) JP2003500368A (en)
KR (1) KR20070058028A (en)
AU (1) AU5273200A (en)
BR (1) BR0010794A (en)
CA (1) CA2373994A1 (en)
MX (1) MXPA01011981A (en)
TW (1) TWI290052B (en)
WO (1) WO2000071163A1 (en)

Families Citing this family (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6727280B2 (en) 1997-01-07 2004-04-27 Sonus Pharmaceuticals, Inc. Method for treating colorectal carcinoma using a taxane/tocopherol formulation
US6632443B2 (en) 2000-02-23 2003-10-14 National Research Council Of Canada Water-soluble compositions of bioactive lipophilic compounds
US20080070981A1 (en) 2000-02-23 2008-03-20 Henryk Borowy-Borowski Water-soluble compositions of bioactive lipophilic compounds
US20030236236A1 (en) * 1999-06-30 2003-12-25 Feng-Jing Chen Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs
MXPA02003203A (en) * 1999-09-27 2004-03-16 Sonus Pharma Inc Compositions of tocol soluble therapeutics.
US6136846A (en) * 1999-10-25 2000-10-24 Supergen, Inc. Formulation for paclitaxel
US6828346B2 (en) * 1999-10-25 2004-12-07 Supergen, Inc. Methods for administration of paclitaxel
US8618085B2 (en) 2000-04-28 2013-12-31 Koasn Biosciences Incorporated Therapeutic formulations of desoxyepothilones
US6589968B2 (en) 2001-02-13 2003-07-08 Kosan Biosciences, Inc. Epothilone compounds and methods for making and using the same
WO2002026208A2 (en) * 2000-09-27 2002-04-04 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
WO2002043765A2 (en) 2000-11-28 2002-06-06 Transform Pharmaceuticals, Inc. Pharmaceutical formulations comprising paclitaxel, derivatives, and pharmaceutically acceptable salts thereof
US6893859B2 (en) 2001-02-13 2005-05-17 Kosan Biosciences, Inc. Epothilone derivatives and methods for making and using the same
FR2820975B1 (en) * 2001-02-21 2004-03-12 Oreal COMPOSITION FOR TOPICAL APPLICATION COMPRISING AT LEAST ONE HYDROXYSTILBENE AND AT LEAST ONE POLYOL FOR SOLUBILIZING THE HYDROXYSTILBENE
US6858227B1 (en) 2001-11-21 2005-02-22 Sonus Pharmaceuticals, Inc. Vitamin E conjugates
AU2002357012A1 (en) * 2001-11-27 2003-06-10 Transform Pharmaceuticals, Inc. Oral pharmaceutical formulations comprising paclitaxel, derivatives and methods of administration thereof
AU2002347541A1 (en) * 2001-12-13 2003-06-23 Ranbaxy Laboratories Limited Stable topical formulation of clarithromycin
DK1463487T3 (en) * 2001-12-19 2010-08-23 Res Dev Foundation Liposomal delivery of vitamin-E based compounds
EP1469860A4 (en) * 2002-01-24 2005-09-07 Yissum Res Dev Co ANTIQUE COMBINATION AND ITS USE
CN100341589C (en) 2002-05-24 2007-10-10 血管技术国际股份公司 Compositions and methods for coating medical implants
FR2840614B1 (en) 2002-06-07 2004-08-27 Flamel Tech Sa POLYAMINOACIDS FUNCTIONALIZED BY ALPHA-TOCOPHEROL AND THEIR PARTICULARLY THERAPEUTIC APPLICATIONS
AU2003291337B2 (en) 2002-11-07 2010-09-09 Kosan Biosciences Incorporated Trans-9,10-dehydroepothilone C and D, analogs thereof and methos of making the same
JPWO2004073692A1 (en) * 2003-02-18 2006-06-01 山下　伸二 Hard capsule of poorly water-soluble drug
US8802116B2 (en) 2003-02-27 2014-08-12 Novasel Australia Pty. Ltd. Poloxamer emulsion preparations
FR2855521B1 (en) 2003-05-28 2005-08-05 Flamel Tech Sa POLYAMINOACIDES FUNCTIONALIZED BY AT LEAST ONE YDROPHOBIC GROUP AND THEIR PARTICULARLY THERAPEUTIC APPLICATIONS.
US7691838B2 (en) 2003-05-30 2010-04-06 Kosan Biosciences Incorporated Method for treating diseases using HSP90-inhibiting agents in combination with antimitotics
EP1498120A1 (en) * 2003-07-18 2005-01-19 Aventis Pharma S.A. Semi-solid formulations for the oral administration of taxoids
CA2536283A1 (en) * 2003-08-20 2005-03-03 Ajinomoto Co., Inc. Pharmaceutical preparations having an improved solubility
EP1510206A1 (en) * 2003-08-29 2005-03-02 Novagali Pharma SA Self-nanoemulsifying oily formulation for the administration of poorly water-soluble drugs
RU2340616C2 (en) * 2003-10-29 2008-12-10 Сонус Фармасьютикалз, Инк. Tocopherol-modified therapeutical drug compounds
TW200522978A (en) 2003-10-29 2005-07-16 Sonus Pharma Inc Tocopherol-modified therapeutic drug compounds
US20050096365A1 (en) * 2003-11-03 2005-05-05 David Fikstad Pharmaceutical compositions with synchronized solubilizer release
CA2550071A1 (en) * 2003-12-19 2005-07-07 Schering Corporation Pharmaceutical compositions
US8003122B2 (en) 2004-03-31 2011-08-23 Cordis Corporation Device for local and/or regional delivery employing liquid formulations of therapeutic agents
US7989490B2 (en) 2004-06-02 2011-08-02 Cordis Corporation Injectable formulations of taxanes for cad treatment
US7659310B2 (en) 2004-04-27 2010-02-09 Formatech, Inc. Methods of enhancing solubility of agents
US7345093B2 (en) 2004-04-27 2008-03-18 Formatech, Inc. Methods of enhancing solubility of compounds
CA2582096C (en) 2004-10-01 2014-01-07 Ramscor, Inc. Conveniently implantable sustained release drug compositions
US8541413B2 (en) 2004-10-01 2013-09-24 Ramscor, Inc. Sustained release eye drop formulations
US9993558B2 (en) 2004-10-01 2018-06-12 Ramscor, Inc. Sustained release eye drop formulations
US20080038316A1 (en) 2004-10-01 2008-02-14 Wong Vernon G Conveniently implantable sustained release drug compositions
GT200500310A (en) * 2004-11-19 2006-06-19 ORGANIC COMPOUNDS
FR2879932B1 (en) * 2004-12-27 2007-03-23 Aventis Pharma Sa FORMULATIONS INJECTABLE OR ORALLY ADMINISTRATIVE OF AZETIDINE DERIVATIVES
KR101387456B1 (en) * 2005-02-09 2014-04-21 산텐 세이야꾸 가부시키가이샤 Liquid formulations for treatment of diseases or conditions
WO2006089290A1 (en) 2005-02-18 2006-08-24 Abraxis Bioscience Inc.. Combinations and modes of administration of therapeutic agents and combination therapy
CN101137395B (en) * 2005-03-14 2012-10-31 株式会社大塚制药工场 Pharmaceutical composition containing poorly water-soluble drug
US7691392B2 (en) 2005-04-29 2010-04-06 Kosan Biosciences Incorporated Method of treating multiple myeloma using 17-AAG or 17-AG or a prodrug of either
ITRM20050418A1 (en) * 2005-08-04 2007-02-05 Sigma Tau Ind Farmaceuti IMMEDIATE RELEASE THERAPEUTIC SYSTEMS FOR THE IMPROVED ORAL ABSORPTION OF 7 - [(E) -T-BUTYLOSSIMINOMETHYL] CAMPTOTECIN.
PL1928405T3 (en) * 2005-09-28 2015-03-31 Auris Medical Ag Pharmaceutical compositions for the treatment of inner ear disorders
EA026670B1 (en) * 2006-03-10 2017-05-31 Лабосвисс Аг Method for solubilizing, dispersing, and stabilizing materials, products manufactured according to said method, and use thereof
KR100917809B1 (en) 2006-05-22 2009-09-18 에스케이케미칼주식회사 Stable Pharmaceutical Composition containing Docetaxel
WO2008026644A1 (en) 2006-08-29 2008-03-06 Fujifilm Corporation Hydrophilic matrix having poorly water-soluble compound sealed therein, and method for producing the same
JP5515075B2 (en) * 2007-01-18 2014-06-11 国立大学法人 千葉大学 Fine particle formulation
WO2009084801A1 (en) * 2007-12-31 2009-07-09 Samyang Corporation Amphiphilic block copolymer micelle composition containing taxane and manufacturing process of the same
KR101024742B1 (en) * 2007-12-31 2011-03-24 주식회사 삼양사 Taxane-containing amphiphilic block copolymer micelle composition and preparation method thereof
US9801818B2 (en) 2007-12-31 2017-10-31 Samyang Biopharmaceuticals Corporation Method for stabilizing amphiphilic block copolymer micelle composition containing poorly water-soluble drug
US8420110B2 (en) 2008-03-31 2013-04-16 Cordis Corporation Drug coated expandable devices
US8409601B2 (en) 2008-03-31 2013-04-02 Cordis Corporation Rapamycin coated expandable devices
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
JP5860399B2 (en) * 2009-08-14 2016-02-16 オプコ ヘルス， インコーポレイテッド Intravenous formulation of neurokinin-1 antagonist
WO2011038073A1 (en) 2009-09-23 2011-03-31 Formatech, Inc. Methods for the preparation of liposomes comprising docetaxel
US10143652B2 (en) 2009-09-23 2018-12-04 Curirx Inc. Methods for the preparation of liposomes
WO2011060352A1 (en) * 2009-11-16 2011-05-19 Ipsen Pharma S.A.S. Pharmaceutical compositions of melanocortin receptor ligands
US20110144578A1 (en) * 2009-12-11 2011-06-16 Stephen Pacetti Hydrophobic therapueutic agent and solid emulsifier coating for drug coated balloon
CN102101863B (en) 2009-12-17 2014-10-15 唐莉 Novel epoxy thiazone compounds and preparation method and application thereof
TWI438009B (en) * 2010-02-19 2014-05-21 Teikoku Pharma Usa Inc Taxane pro-emulsion formulations and methods making and using the same
WO2011116049A1 (en) * 2010-03-17 2011-09-22 Croda, Inc. Polymeric surfactant
LT2552415T (en) 2010-03-29 2016-12-27 Abraxis Bioscience, Llc Methods of treating cancer
CN102985086A (en) 2010-03-29 2013-03-20 阿布拉科斯生物科学有限公司 Methods of enhancing drug delivery and effectiveness of therapeutic agents
KR20180049180A (en) 2010-06-04 2018-05-10 아브락시스 바이오사이언스, 엘엘씨 Methods of treatment of pancreatic cancer
AR082559A1 (en) * 2010-08-04 2012-12-19 Gruenenthal Gmbh PHARMACEUTICAL DOSAGE FORM INCLUDING 6'-FLUORO- (N-METHYL-ON, N-DIMETHYL) -4'-PHENYL-4 ', 9'-DIHYDRO-3'H-SPYRO [CYCLOHEXAN-1,1'-PYRANE [3,4, B] INDOL] -4-AMINE
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
HUE051400T2 (en) 2011-04-28 2021-03-01 Platform Brightworks Two Ltd Improved parenteral formulations of lipophilic drugs and methods for their preparation and use
JO3685B1 (en) * 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc Non-aqueous taxane nanodispersion formulations and methods of using the same
US20170246187A1 (en) 2014-08-28 2017-08-31 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
US9498485B2 (en) 2014-08-28 2016-11-22 Lipocine Inc. Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters
WO2016205423A2 (en) 2015-06-15 2016-12-22 Lipocine Inc. Composition and method for oral delivery of androgen prodrugs
CN105267145B (en) * 2015-11-01 2019-06-21 袁旭东 The self-emulsifying formulation of diphosphonate and related dosage form
GB201522764D0 (en) 2015-12-23 2016-02-03 Nucana Biomed Ltd Formulations of phosphate derivatives
WO2018005412A1 (en) * 2016-06-28 2018-01-04 Tien Yang Der Chemoprotective/chemoactive nanodroplets and methods of use thereof
JP2018024592A (en) * 2016-08-09 2018-02-15 株式会社ブレインヘルス Composition comprising antibiotic
US11559530B2 (en) 2016-11-28 2023-01-24 Lipocine Inc. Oral testosterone undecanoate therapy
EP3424494A1 (en) * 2017-07-07 2019-01-09 SolMic Research GmbH Stable cannabinoid compositions
EP3424493A1 (en) * 2017-07-07 2019-01-09 SolMic Research GmbH Stable cannabinoid compositions
KR102197257B1 (en) * 2017-10-19 2020-12-31 단국대학교 천안캠퍼스 산학협력단 Stabilizing composition for aqueous suspension of entecavir fatty acid esters analogs
CA3107214A1 (en) 2018-07-20 2020-01-23 Lipocine Inc. Liver disease

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5169846A (en) * 1989-10-12 1992-12-08 Crooks Michael J Non-aqueous micellar solutions of anthelmintic benzimidazoles, closantel, or phenothiazine, and insect growth regulators
KR100239799B1 (en) * 1995-01-21 2000-02-01 손경식 Cyclosporin a solid micelle dispersion for oral administration, the preparation method thereof and its solid dosage form
US6458373B1 (en) * 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
NZ314060A (en) * 1997-01-13 1997-08-22 Bernard Charles Sherman Pharmaceutical microemulsion preconcentrate comprising cyclosporin dissolved in a solvent system comprising hydrophobic solvent(s) and surfactant(s)
JPH1149664A (en) * 1997-04-18 1999-02-23 Taisho Pharmaceut Co Ltd Microemulsion
KR20010006480A (en) * 1997-04-18 2001-01-26 우에하라 아끼라 Microemulsion
GB9715759D0 (en) * 1997-07-26 1997-10-01 Danbiosyst Uk New emulsion formulations

Also Published As

Publication number Publication date
EP1185301A1 (en) 2002-03-13
AU5273200A (en) 2000-12-12
WO2000071163A1 (en) 2000-11-30
TWI290052B (en) 2007-11-21
JP2003500368A (en) 2003-01-07
CA2373994A1 (en) 2000-11-30
KR20070058028A (en) 2007-06-07
BR0010794A (en) 2002-06-04

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Legal Events

Date Code Title Description
FG Grant or registration