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MX9804068A - New quinoxalindione derivatives, their preparation and use in medicaments. - Google Patents

New quinoxalindione derivatives, their preparation and use in medicaments.

Info

Publication number
MX9804068A
MX9804068A MX9804068A MX9804068A MX9804068A MX 9804068 A MX9804068 A MX 9804068A MX 9804068 A MX9804068 A MX 9804068A MX 9804068 A MX9804068 A MX 9804068A MX 9804068 A MX9804068 A MX 9804068A
Authority
MX
Mexico
Prior art keywords
medicaments
preparation
new
derivatives
quinoxalindione
Prior art date
Application number
MX9804068A
Other languages
Spanish (es)
Inventor
Andreas Huth
Martin Krueger
Eckhard Ottow
Dieter Seidelmann
Roland Neuhaus
Herbert Schneider
Lechoslaw Turski
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of MX9804068A publication Critical patent/MX9804068A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
    • C07F9/650994—Six-membered rings having the nitrogen atoms in the positions 1 and 4 condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

New quinoxalindone derivatives are disclosed having formula (I), in which R1, R5, R6 and R7 have the meanings given in the description, as well as their preparation and use in medicaments.
MX9804068A 1995-11-24 1998-05-22 New quinoxalindione derivatives, their preparation and use in medicaments. MX9804068A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19545251A DE19545251A1 (en) 1995-11-24 1995-11-24 New quinoxalinedione derivatives, their production and use in pharmaceuticals

Publications (1)

Publication Number Publication Date
MX9804068A true MX9804068A (en) 1998-09-30

Family

ID=7779176

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9804068A MX9804068A (en) 1995-11-24 1998-05-22 New quinoxalindione derivatives, their preparation and use in medicaments.

Country Status (20)

Country Link
EP (1) EP0876357A1 (en)
JP (1) JP2000500471A (en)
KR (1) KR19990071596A (en)
CN (1) CN1202891A (en)
AU (1) AU720083B2 (en)
CA (1) CA2238023A1 (en)
CZ (1) CZ160498A3 (en)
DE (1) DE19545251A1 (en)
EE (1) EE9800163A (en)
HU (1) HUP9902041A3 (en)
IL (1) IL124534A0 (en)
IS (1) IS4740A (en)
MX (1) MX9804068A (en)
NO (1) NO982349L (en)
NZ (1) NZ330492A (en)
PL (1) PL326844A1 (en)
SK (1) SK68298A3 (en)
TR (1) TR199800904T2 (en)
WO (1) WO1997019066A1 (en)
ZA (1) ZA969832B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19737446A1 (en) * 1997-08-22 1999-02-25 Schering Ag Preparation of phosphonic acid derivatives
EP2338492A1 (en) 2009-12-24 2011-06-29 Universidad del Pais Vasco Methods and compositions for the treatment of alzheimer
CN106619953A (en) * 2016-10-31 2017-05-10 山东省海盟生化科技有限公司 External traditional Chinese medicine composition for skin diseases, method for preparing external traditional Chinese medicine composition and application thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO179551C (en) * 1987-11-10 1996-10-30 Novo Nordisk As Analogous Process for Preparing Therapeutically Effective Quinoxaline Compounds
DK69790D0 (en) * 1990-03-16 1990-03-16 Novo Nordisk As HETEROCYCLIC COMPOUNDS, THEIR PREPARATION OF USE
PT101004B (en) * 1991-10-26 1999-10-29 Schering Ag QUINOXALINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM
IL109397A0 (en) * 1993-04-28 1994-07-31 Schering Ag Quinoxalinedione derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
DE4439493A1 (en) * 1994-10-25 1996-05-02 Schering Ag New quinoxalinedione derivatives, their production and use in pharmaceuticals
DE4439492A1 (en) * 1994-10-25 1996-05-02 Schering Ag New quinoxalinedione derivatives, their production and use in pharmaceuticals
DE19519979A1 (en) * 1995-05-24 1996-11-28 Schering Ag New quinoxalinedione derivatives, their production and use in pharmaceuticals

Also Published As

Publication number Publication date
CA2238023A1 (en) 1997-05-29
HUP9902041A2 (en) 2000-04-28
NO982349D0 (en) 1998-05-22
CN1202891A (en) 1998-12-23
AU1867497A (en) 1997-06-11
NO982349L (en) 1998-07-01
ZA969832B (en) 1997-06-17
EE9800163A (en) 1998-12-15
WO1997019066A1 (en) 1997-05-29
EP0876357A1 (en) 1998-11-11
IL124534A0 (en) 1998-12-06
PL326844A1 (en) 1998-10-26
SK68298A3 (en) 1998-12-02
CZ160498A3 (en) 1998-09-16
NZ330492A (en) 1999-10-28
JP2000500471A (en) 2000-01-18
DE19545251A1 (en) 1997-05-28
HUP9902041A3 (en) 2000-07-28
TR199800904T2 (en) 1998-08-21
AU720083B2 (en) 2000-05-25
IS4740A (en) 1998-05-13
KR19990071596A (en) 1999-09-27

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