MX9204866A - SYNTHETIC ARYLPOLYAMINS AS ANTAGONISTS OF EXCITING AMINO ACID NEUROTRANSMITTERS. - Google Patents

SYNTHETIC ARYLPOLYAMINS AS ANTAGONISTS OF EXCITING AMINO ACID NEUROTRANSMITTERS.

Info

Publication number: MX9204866A
Authority: MX; Mexico
Prior art keywords: arylpolyamins; antagonists; synthetic; amino acid; acid neurotransmitters
Prior art date: 1991-08-23

Application number

MX9204866A

Other languages

Spanish (es)

Inventor

Nicholas Alex Saccomano

Robert Alfred Volkmann

Original Assignee

Pfizer

Nps Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-08-23

Filing date

1992-08-21

Publication date

1993-04-01

1992-08-21 Application filed by Pfizer, Nps Pharma Inc filed Critical Pfizer

1993-04-01 Publication of MX9204866A publication Critical patent/MX9204866A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/35—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/40—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/56—Amides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F17/00—Metallocenes
- C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychiatry (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

MX9204866A 1991-08-23 1992-08-21 SYNTHETIC ARYLPOLYAMINS AS ANTAGONISTS OF EXCITING AMINO ACID NEUROTRANSMITTERS. MX9204866A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US74901491A	1991-08-23	1991-08-23

Publications (1)

Publication Number	Publication Date
MX9204866A true MX9204866A (en)	1993-04-01

Family

ID=25011863

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MX9204866A MX9204866A (en)	1991-08-23	1992-08-21	SYNTHETIC ARYLPOLYAMINS AS ANTAGONISTS OF EXCITING AMINO ACID NEUROTRANSMITTERS.

Country Status (14)

Country	Link
EP (1)	EP0641312A1 (en)
JP (1)	JPH06505996A (en)
CN (1)	CN1069969A (en)
AU (1)	AU2426392A (en)
BR (1)	BR9206403A (en)
CA (1)	CA2114798A1 (en)
CZ (1)	CZ39994A3 (en)
FI (1)	FI940833A0 (en)
HU (1)	HU9400503D0 (en)
IL (1)	IL102835A0 (en)
MX (1)	MX9204866A (en)
PT (1)	PT100801A (en)
WO (1)	WO1993004036A1 (en)
ZA (1)	ZA926314B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7087765B2 (en)	1995-06-07	2006-08-08	Nps Pharmaceuticals, Inc.	Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases
US6071970A (en) *	1993-02-08	2000-06-06	Nps Pharmaceuticals, Inc.	Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases
US6750244B2 (en)	1993-02-08	2004-06-15	Nps Pharmaceuticals, Inc.	Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases
US6211245B1 (en)	1993-02-08	2001-04-03	Nps Pharmaceuticals, Inc.	Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases
US6017965A (en) *	1993-02-08	2000-01-25	Nps Pharmaceuticals, Inc.	Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases
PT743853E (en) *	1994-02-08	2001-10-31	Nps Pharma Inc	ACTIVE COMPOUNDS IN A NEW LOCATION IN CALCIO CANIS ACTIVATED BY A UTEIS RECEIVER FOR THE TREATMENT OF NEUROLOGICAL DISTURBACTIONS AND DISEASES
US20010004460A1 (en) *	1995-06-08	2001-06-21	Carla Rasmussen Klittich	Process for the preparation of rice seed for sowing
US7087648B1 (en) *	1997-10-27	2006-08-08	The Regents Of The University Of California	Methods for modulating macrophage proliferation using polyamine analogs
AU2003231670B2 (en) *	1997-10-27	2006-06-08	Slil Biomedical Corporation	Methods for modulating macrophage proliferation using polyamine analogs
US8198334B2 (en)	1997-10-27	2012-06-12	Pathologica Llc	Methods for modulating macrophage proliferation in ocular disease using polyamine analogs
US20030130356A1 (en)	2001-10-16	2003-07-10	Slil Biomedical Corporation	Oligoamine compounds and derivatives thereof for cancer therapy
CA2538159A1 (en) *	2003-09-09	2005-03-17	University Of Florida Research Foundation, Inc.	Polyamine-metal chelator conjugates
CN103073448B (en) *	2012-12-29	2015-11-18	河南大学	Containing the polyamine derivative and its preparation method and application of aromatic ring structure

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5037846A (en) *	1990-01-02	1991-08-06	Pfizer Inc.	Indolyl-3 polyamines and their use as antagonists of excitatory amino acid neurotransmitters

1992
- 1992-08-10 AU AU24263/92A patent/AU2426392A/en not_active Abandoned
- 1992-08-10 HU HU9400503A patent/HU9400503D0/en unknown
- 1992-08-10 CZ CS94399A patent/CZ39994A3/en unknown
- 1992-08-10 EP EP92916921A patent/EP0641312A1/en not_active Withdrawn
- 1992-08-10 BR BR9206403A patent/BR9206403A/en not_active Application Discontinuation
- 1992-08-10 CA CA002114798A patent/CA2114798A1/en not_active Abandoned
- 1992-08-10 WO PCT/US1992/006482 patent/WO1993004036A1/en not_active Application Discontinuation
- 1992-08-10 JP JP5504331A patent/JPH06505996A/en active Pending
- 1992-08-17 IL IL102835A patent/IL102835A0/en unknown
- 1992-08-21 PT PT100801A patent/PT100801A/en not_active Application Discontinuation
- 1992-08-21 ZA ZA926314A patent/ZA926314B/en unknown
- 1992-08-21 MX MX9204866A patent/MX9204866A/en unknown
- 1992-08-22 CN CN92109681A patent/CN1069969A/en active Pending
1994
- 1994-02-22 FI FI940833A patent/FI940833A0/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU2426392A (en)	1993-03-16
FI940833A (en)	1994-02-22
CZ39994A3 (en)	1994-11-16
IL102835A0 (en)	1993-01-31
BR9206403A (en)	1994-12-27
FI940833A0 (en)	1994-02-22
JPH06505996A (en)	1994-07-07
CA2114798A1 (en)	1993-03-04
ZA926314B (en)	1994-02-21
PT100801A (en)	1993-09-30
HU9400503D0 (en)	1994-05-30
CN1069969A (en)	1993-03-17
EP0641312A1 (en)	1995-03-08
WO1993004036A1 (en)	1993-03-04

Publication	Publication Date	Title
ATE82273T1 (en)	1992-11-15	LEUCOTRIEN ANTAGONISTS.
DE68915207D1 (en)	1994-06-16	Amino acid derivatives.
DE59008394D1 (en)	1995-03-16	Amino acid amide derivatives.
DK340088A (en)	1988-12-23	AMINO ACID DERIVATIVES
NO901399L (en)	1990-10-01	Amino acid derivative.
NO903832D0 (en)	1990-09-03	Amino acid derivative.
NO901033L (en)	1990-09-07	Amino acid derivative.
MX9204866A (en)	1993-04-01	SYNTHETIC ARYLPOLYAMINS AS ANTAGONISTS OF EXCITING AMINO ACID NEUROTRANSMITTERS.
NO892416D0 (en)	1989-06-13	Polyamides.
FI901765A0 (en)	1990-04-06	SYNTHETIC GEN.
DK530888D0 (en)	1988-09-23	LEUKOTRIEN -LTD4- AND - LTB4 ANTAGONISTS
BR9206404A (en)	1994-12-27	Synthetic heteroaryl-polyamines as antagonists of excitatory amino acid neurotransmitters
NO884434L (en)	1989-04-07	Amino acid derivative.
FI901763A0 (en)	1990-04-06	SYNTHETIC GEN.
NO901533L (en)	1990-10-08	Amino acid derivative.
DE59301060D1 (en)	1996-01-18	Substituted amino acid amides.
IT8224380A0 (en)	1982-11-23	PHOSPHYNYLALKANOIC AMINO ACIDS USEFUL AS HYPOTENSIVE AGENTS.
NO901519L (en)	1990-10-05	Amino acid derivative.
MX9203754A (en)	1992-09-30	LEUCOTRENE ANTAGONISTS.
FI884255A0 (en)	1988-09-15	L-ASPARTYL-3- (BICYCLOALKYL) -L-ALANINALKYLESTRAR MED HOEG SOETHETSGRAD.
DE3850945D1 (en)	1994-09-08	Polyamide composition.
MX9203766A (en)	1992-09-01	LEUCOTRENE ANTAGONISTS.
MX9203743A (en)	1992-09-01	THIOPHENYLALCANOIC ACIDS USEFUL AS LEUCOTRENE ANTAGONISTS
MX9203198A (en)	1992-09-01	DERIVATIVES OF POLYAMIDES AS ANTINEOPLASTIC AGENTS.
LV5808A4 (en)	1997-02-20	Lh1 antagonists