MX9203460A - Nuevos analogos cc-1065 que tienen dos subunidades cpi. - Google Patents

Nuevos analogos cc-1065 que tienen dos subunidades cpi.

Info

Publication number: MX9203460A
Authority: MX; Mexico
Prior art keywords: new analogs; cpi; subunits; cpi subunits; analogs
Prior art date: 1988-09-12

Application number

MX9203460A

Other languages

English (en)

Inventor

Robert C Kelly

Paul A Aristoff

Original Assignee

Upjohn Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-09-12

Filing date

1989-08-07

Publication date

1992-09-01

1989-08-07 Application filed by Upjohn Co filed Critical Upjohn Co

1989-08-07 Priority claimed from PCT/US1989/003329 external-priority patent/WO1990002746A1/en

1992-09-01 Publication of MX9203460A publication Critical patent/MX9203460A/es

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

MX9203460A 1988-09-12 1989-08-07 Nuevos analogos cc-1065 que tienen dos subunidades cpi. MX9203460A (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US24335088A	1988-09-12	1988-09-12
PCT/US1989/003329 WO1990002746A1 (en)	1988-09-12	1989-08-07	Novel cc-1065 analogs having two cpi subunits

Publications (1)

Publication Number	Publication Date
MX9203460A true MX9203460A (es)	1992-09-01

Family

ID=26779868

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MX9203460A MX9203460A (es)	1988-09-12	1989-08-07	Nuevos analogos cc-1065 que tienen dos subunidades cpi.

Country Status (3)

Country	Link
EP (1)	EP0359454B1 (es)
ES (1)	ES2153814T3 (es)
MX (1)	MX9203460A (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5258383A (en) *	1991-06-28	1993-11-02	Kyowa Hakko Kogyo Co., Ltd.	DC-89 derivatives
ES2149768T3 (es) *	1992-03-25	2000-11-16	Immunogen Inc	Conjugados de agentes enlazantes de celulas derivados de cc-1065.
US5248691A (en) *	1992-09-03	1993-09-28	Eli Lilly And Company	Furanoindolines
ES2074957B1 (es) *	1993-11-19	1996-06-16	Univ Santiago Compostela	Nuevos derivados de pirrolo(3,2-e)indol, procedimiento para su preparacion y aplicaciones.
US5786377A (en) *	1993-11-19	1998-07-28	Universidad De Santiago De Compostela	Pyrrolo 3,2-E!indol derivatives, process for the preparation thereof and applications
US6924276B2 (en)	2001-09-10	2005-08-02	Warner-Lambert Company	Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors
JP5203701B2 (ja) *	2004-05-12	2013-06-05	プロテオテック・インコーポレイテッド	アミロイド疾患、及びシヌクレイノパチー治療用置換ｎ−アリールベンズアミド、及び関連化合物
MX2011004625A (es) *	2008-11-03	2011-07-20	Syntarga Bv	Analogos cc-1065 novedosos y sus conjugados.
PT3069735T (pt)	2014-01-10	2018-05-18	Synthon Biopharmaceuticals Bv	Adc de duocarmicina para utilização no tratamento de cancro da bexiga
PT3092010T (pt)	2014-01-10	2018-09-28	Synthon Biopharmaceuticals Bv	Método para purificação de conjugados anticorpo-fármaco ligados por cys
PT2948183T (pt)	2014-01-10	2016-07-13	Univ Yale	Conjugados anticorpo-fármaco de duocarmicina para utilização no tratamento de cancro do endométrio
WO2015110935A1 (en) *	2014-01-27	2015-07-30	Pfizer Inc.	Bifunctional cytotoxic agents
SG11201706991YA (en)	2015-03-20	2017-10-30	Pfizer	Bifunctional cytotoxic agents containing the cti pharmacophore

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4301248A (en) *	1979-12-21	1981-11-17	Bristol-Myers Company	Fermentation process for making rachelmycin
US4912227A (en) *	1984-02-21	1990-03-27	The Upjohn Company	1,2,8,8A-tetrahydrocyclopropa(c)pyrrolo(3,2-e)-indol-4-(5H)-ones and related compounds
CA1238907A (en) *	1984-02-21	1988-07-05	Robert C. Kelly	1,2,8,8a-tetrahydrocyclopropa¬c\|pyrrolo(3,2-e)- indol-4(5h)-ones and related compounds
WO1988005659A1 (en) *	1987-02-06	1988-08-11	Zymogenetics, Inc.	Human proteins having anticoagulant and anti-inflammatory activity

1989
- 1989-08-07 MX MX9203460A patent/MX9203460A/es unknown
- 1989-09-04 EP EP89308920A patent/EP0359454B1/en not_active Expired - Lifetime
- 1989-09-04 ES ES89308920T patent/ES2153814T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0359454A1 (en)	1990-03-21
EP0359454B1 (en)	2000-12-27
ES2153814T3 (es)	2001-03-16

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