MX392374B - Peptidos terapeuticos relacionados con mots-c. - Google Patents
Peptidos terapeuticos relacionados con mots-c.Info
- Publication number
- MX392374B MX392374B MX2019003567A MX2019003567A MX392374B MX 392374 B MX392374 B MX 392374B MX 2019003567 A MX2019003567 A MX 2019003567A MX 2019003567 A MX2019003567 A MX 2019003567A MX 392374 B MX392374 B MX 392374B
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- mots
- therapeutic peptides
- peptides related
- treating
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 208000016097 disease of metabolism Diseases 0.000 abstract 1
- 230000004129 fatty acid metabolism Effects 0.000 abstract 1
- 208000019423 liver disease Diseases 0.000 abstract 1
- 208000030159 metabolic disease Diseases 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Child & Adolescent Psychology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
Abstract
La presente invención se refiere a péptidos y análogos peptídicos y métodos para tratar una enfermedad metabólica, por ejemplo, obesidad, diabetes, métodos para tratar cáncer, métodos para tratar una enfermedad hepática, y métodos para modular el metabolismo del ácido graso.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662401123P | 2016-09-28 | 2016-09-28 | |
PCT/US2017/053597 WO2018064098A1 (en) | 2016-09-28 | 2017-09-27 | Therapeutic mots-c related peptides |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2019003567A MX2019003567A (es) | 2019-12-02 |
MX392374B true MX392374B (es) | 2025-03-24 |
Family
ID=60164788
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019003567A MX392374B (es) | 2016-09-28 | 2017-09-27 | Peptidos terapeuticos relacionados con mots-c. |
Country Status (11)
Country | Link |
---|---|
US (3) | US11111271B2 (es) |
EP (1) | EP3519431A1 (es) |
JP (1) | JP7035033B2 (es) |
KR (1) | KR20190057110A (es) |
CN (1) | CN110072883A (es) |
AU (1) | AU2017336440B2 (es) |
CA (1) | CA3038292A1 (es) |
IL (1) | IL265463A (es) |
MX (1) | MX392374B (es) |
TW (1) | TW201819398A (es) |
WO (1) | WO2018064098A1 (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11111271B2 (en) * | 2016-09-28 | 2021-09-07 | Cohbar, Inc. | Therapeutic peptides |
CN112040958A (zh) * | 2018-03-27 | 2020-12-04 | 科巴公司 | 含肽调配物 |
JP7344422B2 (ja) * | 2018-06-07 | 2023-09-14 | 漢義生物科技(北京)有限公司 | 糖尿病予防・治療用の医薬品組成物及びその用途 |
KR20210121132A (ko) * | 2019-01-28 | 2021-10-07 | 코바, 인크. | 치료용 펩티드 |
CN110818804B (zh) * | 2019-10-21 | 2021-06-04 | 兰州大学 | 脑靶向肽及其在制备增强记忆药物中的应用 |
CN115867648A (zh) * | 2020-02-14 | 2023-03-28 | 西北大学 | 将用于遗传密码重编程的化学底物扩展至包括长链碳和环状氨基酸 |
IL303813A (en) | 2020-12-21 | 2023-08-01 | Univ Cornell | Peptide-linked drug delivery system |
CN113440599A (zh) * | 2021-08-11 | 2021-09-28 | 南京市妇幼保健院 | MOTS-c肽及其衍生物在制备妊娠期糖尿病治疗药物中的应用 |
CN113876929B (zh) * | 2021-11-22 | 2024-02-23 | 中国人民解放军陆军军医大学 | 肽MOTS-c在制备治疗帕金森药物中的应用 |
CN115444926A (zh) * | 2022-05-10 | 2022-12-09 | 江南大学 | MOTS-c肽及其衍生物在制备放射性肺损伤治疗药物中的应用 |
WO2023249904A1 (en) * | 2022-06-20 | 2023-12-28 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Compositions and methods for treating diabetes |
US12064467B2 (en) * | 2022-10-28 | 2024-08-20 | Transdermal Biotechnology, Inc. | Systems and methods for delivery of humanin or other peptides |
Family Cites Families (39)
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EP0272253A4 (en) | 1986-03-07 | 1990-02-05 | Massachusetts Inst Technology | METHOD FOR IMPROVING GLYCOPROTE INSTABILITY. |
US5858351A (en) | 1996-01-18 | 1999-01-12 | Avigen, Inc. | Methods for delivering DNA to muscle cells using recombinant adeno-associated virus vectors |
US5846528A (en) | 1996-01-18 | 1998-12-08 | Avigen, Inc. | Treating anemia using recombinant adeno-associated virus virions comprising an EPO DNA sequence |
US6015709A (en) | 1997-08-26 | 2000-01-18 | Ariad Pharmaceuticals, Inc. | Transcriptional activators, and compositions and uses related thereto |
WO2001076532A2 (en) | 2000-04-11 | 2001-10-18 | Cogent Neuroscience, Inc. | Compositions and methods for diagnosing and treating conditions, disorders, or diseases involving cell death |
WO2001089583A2 (en) | 2000-05-23 | 2001-11-29 | Neurologix, Inc. | Glutamic acid decarboxylase (gad)_delivery system for treating neurodegenerative diseases |
US7588757B2 (en) | 2001-03-14 | 2009-09-15 | Genzyme Corporation | Methods of treating Parkinson's disease using recombinant adeno-associated virus virions |
DK2573170T3 (en) | 2001-12-17 | 2018-04-09 | Univ Pennsylvania | Sequences of adeno-associated virus (AAV) serotype 9, vectors containing them, and their use |
US20070015238A1 (en) | 2002-06-05 | 2007-01-18 | Snyder Richard O | Production of pseudotyped recombinant AAV virions |
EP1587540B1 (en) | 2003-01-09 | 2021-09-15 | MacroGenics, Inc. | IDENTIFICATION AND ENGINEERING OF ANTIBODIES WITH VARIANT Fc REGIONS AND METHODS OF USING SAME |
US20040258666A1 (en) | 2003-05-01 | 2004-12-23 | Passini Marco A. | Gene therapy for neurometabolic disorders |
TWI353991B (en) | 2003-05-06 | 2011-12-11 | Syntonix Pharmaceuticals Inc | Immunoglobulin chimeric monomer-dimer hybrids |
US8283151B2 (en) | 2005-04-29 | 2012-10-09 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Isolation, cloning and characterization of new adeno-associated virus (AAV) serotypes |
EP1857552A1 (en) | 2006-05-20 | 2007-11-21 | Cargill Incorporated | Thermostable xylose isomerase enzyme |
US7846445B2 (en) | 2005-09-27 | 2010-12-07 | Amunix Operating, Inc. | Methods for production of unstructured recombinant polymers and uses thereof |
AR059371A1 (es) | 2006-02-08 | 2008-03-26 | Genzyme Corp | Terapia genica para la enfermedad de niemann-pick tipo a |
WO2007120542A2 (en) | 2006-03-30 | 2007-10-25 | The Board Of Trustees Of The Leland Stanford Junior University | Aav capsid library and aav capsid proteins |
US8292769B2 (en) | 2006-11-22 | 2012-10-23 | Lawson Jr Thomas Towles | Transmission |
US8309525B2 (en) | 2007-05-30 | 2012-11-13 | Albert Einstein College Of Medicine Of Yeshiva University | Treatment of type 2 diabetes, metabolic syndrome, myocardial injury and neurodegeneration with humanin and analogs thereof |
EP2170387A4 (en) * | 2007-06-29 | 2011-01-19 | Centocor Ortho Biotech Inc | ANTI-MCP-1 ANTIBODIES, COMPOSITIONS, METHODS AND USES |
JP2010536341A (ja) | 2007-08-15 | 2010-12-02 | アムニクス, インコーポレイテッド | 生物学的に活性なポリペプチドの特性を改変するための組成物および方法 |
US7998928B2 (en) | 2007-09-14 | 2011-08-16 | The Regents Of The University Of California | Method of treatment of type-1 diabetes with a humanin analogue |
TWI573806B (zh) | 2008-04-17 | 2017-03-11 | 巴克斯歐塔公司 | 生物活性胜肽 |
US8637470B2 (en) | 2008-05-01 | 2014-01-28 | The Regents Of The University Of California | Small humanin-like peptides |
US9217155B2 (en) | 2008-05-28 | 2015-12-22 | University Of Massachusetts | Isolation of novel AAV'S and uses thereof |
PE20120332A1 (es) | 2008-12-19 | 2012-04-14 | Univ Indiana Res & Tech Corp | Profarmacos de peptido de la superfamilia de glucagon basado en amida |
AU2011238708B2 (en) | 2010-03-29 | 2016-02-11 | The Trustees Of The University Of Pennsylvania | Pharmacologically Induced Transgene Ablation system |
DK2826860T3 (en) | 2010-04-23 | 2018-12-03 | Univ Massachusetts | CNS targeting AAV vectors and methods for their use |
WO2012009709A1 (en) * | 2010-07-16 | 2012-01-19 | Sudhir Paul | Hiv cd4 binding site based covalent immunogen compositions |
CN107828820B (zh) | 2010-10-27 | 2022-06-07 | 学校法人自治医科大学 | 用于向神经系统细胞导入基因的腺相关病毒粒子 |
EP2678433B1 (en) | 2011-02-22 | 2017-05-03 | California Institute of Technology | Delivery of proteins using adeno-associated virus (aav) vectors |
US20130123168A1 (en) | 2011-06-17 | 2013-05-16 | The Regents Of The University Of California | Humanin and humanin-analogues for the management of atherosclerosis |
US20140296139A1 (en) | 2013-03-15 | 2014-10-02 | The Regents Of The University Of California | Mitochondrial-derived peptide mots3 regulates metabolism and cell survival |
CN105324125A (zh) | 2013-03-15 | 2016-02-10 | 印第安纳大学研究及科技有限公司 | 具有长效的前体药物 |
SG11201509419QA (en) | 2013-05-15 | 2015-12-30 | Univ Minnesota | Adeno-associated virus mediated gene transfer to the central nervous system |
AU2015252797C1 (en) | 2014-05-02 | 2021-04-22 | Genzyme Corporation | AAV vectors for retinal and CNS gene therapy |
MX2017005834A (es) | 2014-11-05 | 2017-11-17 | Voyager Therapeutics Inc | Polinucleotidos aad para el tratamiento de la enfermedad de parkinson. |
MA41451A (fr) | 2015-02-04 | 2017-12-12 | Univ Washington | Constructions anti-tau |
US11111271B2 (en) | 2016-09-28 | 2021-09-07 | Cohbar, Inc. | Therapeutic peptides |
-
2017
- 2017-09-27 US US16/336,089 patent/US11111271B2/en active Active
- 2017-09-27 MX MX2019003567A patent/MX392374B/es unknown
- 2017-09-27 KR KR1020197012168A patent/KR20190057110A/ko not_active Ceased
- 2017-09-27 CN CN201780059877.XA patent/CN110072883A/zh active Pending
- 2017-09-27 WO PCT/US2017/053597 patent/WO2018064098A1/en not_active Application Discontinuation
- 2017-09-27 EP EP17788342.8A patent/EP3519431A1/en active Pending
- 2017-09-27 TW TW106133165A patent/TW201819398A/zh unknown
- 2017-09-27 CA CA3038292A patent/CA3038292A1/en active Pending
- 2017-09-27 JP JP2019517875A patent/JP7035033B2/ja active Active
- 2017-09-27 AU AU2017336440A patent/AU2017336440B2/en not_active Ceased
-
2019
- 2019-03-19 IL IL265463A patent/IL265463A/en unknown
-
2021
- 2021-08-04 US US17/393,944 patent/US11332497B2/en active Active
-
2022
- 2022-04-11 US US17/717,982 patent/US11753445B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US11111271B2 (en) | 2021-09-07 |
KR20190057110A (ko) | 2019-05-27 |
TW201819398A (zh) | 2018-06-01 |
JP2020501514A (ja) | 2020-01-23 |
WO2018064098A1 (en) | 2018-04-05 |
AU2017336440B2 (en) | 2022-06-02 |
MX2019003567A (es) | 2019-12-02 |
US20200181197A1 (en) | 2020-06-11 |
AU2017336440A1 (en) | 2019-04-11 |
US20220242912A1 (en) | 2022-08-04 |
CN110072883A (zh) | 2019-07-30 |
IL265463A (en) | 2019-05-30 |
CA3038292A1 (en) | 2018-04-05 |
EP3519431A1 (en) | 2019-08-07 |
US11332497B2 (en) | 2022-05-17 |
US11753445B2 (en) | 2023-09-12 |
US20210363187A1 (en) | 2021-11-25 |
JP7035033B2 (ja) | 2022-03-14 |
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