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MX377448B - Ligadores de nucleotidos modificados. - Google Patents

Ligadores de nucleotidos modificados.

Info

Publication number
MX377448B
MX377448B MX2017001694A MX2017001694A MX377448B MX 377448 B MX377448 B MX 377448B MX 2017001694 A MX2017001694 A MX 2017001694A MX 2017001694 A MX2017001694 A MX 2017001694A MX 377448 B MX377448 B MX 377448B
Authority
MX
Mexico
Prior art keywords
modified nucleotide
nucleotide linkers
linkers
preparing
increasing
Prior art date
Application number
MX2017001694A
Other languages
English (en)
Other versions
MX2017001694A (es
Inventor
Xiaohai Liu
Xiaolin Wu
Original Assignee
Illumina Cambridge Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Illumina Cambridge Ltd filed Critical Illumina Cambridge Ltd
Publication of MX2017001694A publication Critical patent/MX2017001694A/es
Publication of MX377448B publication Critical patent/MX377448B/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/14Pyrrolo-pyrimidine radicals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Algunas modalidades de la presente solicitud se refieren a nuevos enlazadores de nucleótido modificados para incrementar la eficiencia de la incorporación de nucleótido en secuenciar mediante aplicaciones de síntesis. También se proporcionan métodos para preparar estos enlazadores de nucleótido modificados con los mismos.
MX2017001694A 2014-08-08 2015-08-06 Ligadores de nucleotidos modificados. MX377448B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1414098.2A GB201414098D0 (en) 2014-08-08 2014-08-08 Modified nucleotide linkers
PCT/GB2015/052282 WO2016020691A1 (en) 2014-08-08 2015-08-06 Modified nucleotide linkers

Publications (2)

Publication Number Publication Date
MX2017001694A MX2017001694A (es) 2017-04-27
MX377448B true MX377448B (es) 2025-03-10

Family

ID=51629525

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2020009401A MX385213B (es) 2014-08-08 2015-08-06 Ligadores de nucleótidos modificados.
MX2017001694A MX377448B (es) 2014-08-08 2015-08-06 Ligadores de nucleotidos modificados.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2020009401A MX385213B (es) 2014-08-08 2015-08-06 Ligadores de nucleótidos modificados.

Country Status (19)

Country Link
US (3) US10190157B2 (es)
EP (2) EP3564252B1 (es)
JP (3) JP6563482B2 (es)
KR (2) KR102287718B1 (es)
CN (2) CN111704643A (es)
AU (2) AU2015298469B2 (es)
BR (2) BR112017002251B1 (es)
CA (1) CA2957382C (es)
DK (2) DK3177634T3 (es)
ES (2) ES2773438T3 (es)
GB (1) GB201414098D0 (es)
IL (1) IL250498B (es)
MX (2) MX385213B (es)
MY (1) MY195167A (es)
NZ (1) NZ728810A (es)
RU (1) RU2699993C2 (es)
SG (3) SG10201900948PA (es)
WO (1) WO2016020691A1 (es)
ZA (1) ZA201700838B (es)

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