[go: up one dir, main page]

MX373330B - Composiciones y métodos que comprenden bupropion o compuestos relacionados y dextrometorfano. - Google Patents

Composiciones y métodos que comprenden bupropion o compuestos relacionados y dextrometorfano.

Info

Publication number
MX373330B
MX373330B MX2016005867A MX2016005867A MX373330B MX 373330 B MX373330 B MX 373330B MX 2016005867 A MX2016005867 A MX 2016005867A MX 2016005867 A MX2016005867 A MX 2016005867A MX 373330 B MX373330 B MX 373330B
Authority
MX
Mexico
Prior art keywords
dextromethorphan
compositions
bupropion
methods
related compounds
Prior art date
Application number
MX2016005867A
Other languages
English (en)
Other versions
MX2016005867A (es
Inventor
Herriot Tabuteau
Original Assignee
Antecip Bioventures Ii Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antecip Bioventures Ii Llc filed Critical Antecip Bioventures Ii Llc
Publication of MX2016005867A publication Critical patent/MX2016005867A/es
Publication of MX373330B publication Critical patent/MX373330B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

En esta divulgación se describe un método para tratar un trastorno neurológico mediante la administración de un compuesto antidepresivo y dextrometorfano a un ser humano que lo necesita. Este método puede ser útil para seres humanos, los cuales son metabolizadores extensos de dextrometorfano. También se describen composiciones, medicamentos y formas de dosificación que comprenden compuestos antidepresivos y dextrometorfano.
MX2016005867A 2013-11-05 2014-11-05 Composiciones y métodos que comprenden bupropion o compuestos relacionados y dextrometorfano. MX373330B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361900354P 2013-11-05 2013-11-05
PCT/US2014/064184 WO2015069809A1 (en) 2013-11-05 2014-11-05 Compositions and methods comprising bupropion or related compounds and dextromethorphan

Publications (2)

Publication Number Publication Date
MX2016005867A MX2016005867A (es) 2016-07-15
MX373330B true MX373330B (es) 2025-03-05

Family

ID=53042051

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2016005867A MX373330B (es) 2013-11-05 2014-11-05 Composiciones y métodos que comprenden bupropion o compuestos relacionados y dextrometorfano.
MX2020004075A MX2020004075A (es) 2013-11-05 2014-11-05 Composiciones y metodos que comprenden bupropion o compuestos relacionados y dextrometorfano.
MX2021015234A MX2021015234A (es) 2013-11-05 2016-05-04 Composiciones y metodos que comprenden bupropion o compuestos relacionados y dextrometorfano.

Family Applications After (2)

Application Number Title Priority Date Filing Date
MX2020004075A MX2020004075A (es) 2013-11-05 2014-11-05 Composiciones y metodos que comprenden bupropion o compuestos relacionados y dextrometorfano.
MX2021015234A MX2021015234A (es) 2013-11-05 2016-05-04 Composiciones y metodos que comprenden bupropion o compuestos relacionados y dextrometorfano.

Country Status (12)

Country Link
EP (3) EP3065742A4 (es)
JP (4) JP6605485B2 (es)
KR (4) KR102603013B1 (es)
CN (7) CN106163522A (es)
AU (6) AU2014346807B2 (es)
CA (3) CA3154845C (es)
IL (3) IL298972A (es)
MX (3) MX373330B (es)
MY (1) MY179696A (es)
NZ (5) NZ758432A (es)
SG (4) SG10201911816XA (es)
WO (1) WO2015069809A1 (es)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11969421B2 (en) 2013-11-05 2024-04-30 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11478468B2 (en) 2013-11-05 2022-10-25 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11253492B2 (en) 2013-11-05 2022-02-22 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11439636B1 (en) 2013-11-05 2022-09-13 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11517543B2 (en) 2013-11-05 2022-12-06 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
NZ758432A (en) * 2013-11-05 2021-07-30 Antecip Bioventures Ii Llc Compositions and methods comprising bupropion or related compounds and dextromethorphan
US20200338022A1 (en) 2019-01-07 2020-10-29 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11617747B2 (en) 2013-11-05 2023-04-04 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11273133B2 (en) 2013-11-05 2022-03-15 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11433067B2 (en) 2013-11-05 2022-09-06 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11617728B2 (en) 2013-11-05 2023-04-04 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11298352B2 (en) 2013-11-05 2022-04-12 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11285118B2 (en) 2013-11-05 2022-03-29 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US12109178B2 (en) 2013-11-05 2024-10-08 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11207281B2 (en) 2013-11-05 2021-12-28 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11541021B2 (en) 2013-11-05 2023-01-03 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11571399B2 (en) 2013-11-05 2023-02-07 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11291665B2 (en) 2013-11-05 2022-04-05 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11147808B2 (en) 2013-11-05 2021-10-19 Antecip Bioventures Ii Llc Method of decreasing the fluctuation index of dextromethorphan
US11590124B2 (en) 2013-11-05 2023-02-28 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11571417B2 (en) 2013-11-05 2023-02-07 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11576877B2 (en) 2013-11-05 2023-02-14 Antecip Bioventures Ii Llc Bupropion as modulator of drug activity
US12194006B2 (en) 2013-11-05 2025-01-14 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11344544B2 (en) 2013-11-05 2022-05-31 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11191739B2 (en) 2013-11-05 2021-12-07 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11123344B2 (en) 2013-11-05 2021-09-21 Axsome Therapeutics, Inc. Bupropion as a modulator of drug activity
US11576909B2 (en) 2013-11-05 2023-02-14 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US20220233470A1 (en) 2013-11-05 2022-07-28 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11357744B2 (en) 2013-11-05 2022-06-14 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11426370B2 (en) 2013-11-05 2022-08-30 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11253491B2 (en) 2013-11-05 2022-02-22 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11298351B2 (en) 2013-11-05 2022-04-12 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11534414B2 (en) 2013-11-05 2022-12-27 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11596627B2 (en) 2013-11-05 2023-03-07 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11510918B2 (en) 2013-11-05 2022-11-29 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11426401B2 (en) 2013-11-05 2022-08-30 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11197839B2 (en) 2013-11-05 2021-12-14 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11311534B2 (en) 2013-11-05 2022-04-26 Antecip Bio Ventures Ii Llc Bupropion as a modulator of drug activity
US11382874B2 (en) 2013-11-05 2022-07-12 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11541048B2 (en) 2013-11-05 2023-01-03 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11419867B2 (en) 2013-11-05 2022-08-23 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11497721B2 (en) 2013-11-05 2022-11-15 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11234946B2 (en) 2013-11-05 2022-02-01 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11524007B2 (en) 2013-11-05 2022-12-13 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11229640B2 (en) 2013-11-05 2022-01-25 Antecip Bioventures Ii Llc Combination of dextromethorphan and bupropion for treating depression
US11364233B2 (en) 2013-11-05 2022-06-21 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11129826B2 (en) 2013-11-05 2021-09-28 Axsome Therapeutics, Inc. Bupropion as a modulator of drug activity
RU2017112747A (ru) * 2014-09-14 2018-10-15 Аванир Фармасьютикалз, Инк. Фармацевтические композиции, содержащие декстрометорфановое соединение и хинидин для лечения возбуждения при деменции
MX2017006653A (es) * 2014-11-21 2017-10-31 Antecip Bioventures Ii Llc Metodos para modular los niveles de fármaco en plasma mediante el uso de eritrohidroxibupropión.
WO2017165845A1 (en) * 2016-03-24 2017-09-28 Antecip Bioventures Ii Llc Compositions and methods for increasing the metabolic lifetime of dextromethorphan and related pharmacodynamic effects
TWI795446B (zh) 2017-10-04 2023-03-11 美商神經治療股份有限公司 右旋美索芬(dextromethorphan)經皮輸送裝置
KR20210110654A (ko) * 2019-01-07 2021-09-08 안테씨프 바이오벤쳐스 투 엘엘씨 우울증 치료를 위한 덱스트로메토르판과 부프로피온의 조합
US20230225995A1 (en) * 2019-01-07 2023-07-20 Antecip Bioventures Ii Llc Combination of dextromethorphan and bupropion for treating depression
KR20220161414A (ko) * 2020-03-30 2022-12-06 안테씨프 바이오벤쳐스 투 엘엘씨 신경 장애 치료를 위한 부프로피온과 덱스트로메토르판 조합의 용도
WO2022017300A1 (zh) 2020-07-20 2022-01-27 深圳信立泰药业股份有限公司 一种药物组合物及其应用
WO2022119981A1 (en) 2020-12-01 2022-06-09 Antecip Bioventures Ii Llc Bupropion and dextromethrophan for reduction of suicide risk in depression patients
JP2024503114A (ja) * 2021-01-18 2024-01-24 アンテシップ バイオベンチャーズ トゥー エルエルシー 神経精神疾患に対する抗うつ剤とデキストロメトルファンとの組み合わせ
CN112999350A (zh) * 2021-02-23 2021-06-22 北京斯利安药业有限公司 一种药物组合物、复方制剂及其制备方法与应用
US12036191B1 (en) 2022-06-30 2024-07-16 Antecip Bioventures Ii Llc Treatment of poor metabolizers of dextromethorphan with a combination of bupropion and dextromethorphan
US12156914B2 (en) 2022-06-30 2024-12-03 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising bupropion and cysteine
CN118785900A (zh) * 2022-06-30 2024-10-15 艾克萨姆治疗公司 包含安非他酮和半胱氨酸的药物组合物
US11717518B1 (en) 2022-06-30 2023-08-08 Antecip Bioventures Ii Llc Bupropion dosage forms with reduced food and alcohol dosing effects
US12194036B2 (en) 2022-07-07 2025-01-14 Antecip Bioventures Ii Llc Combination of dextromethorphan and bupropion for treating depression
US11730706B1 (en) 2022-07-07 2023-08-22 Antecip Bioventures Ii Llc Treatment of depression in certain patient populations
US11844797B1 (en) 2023-04-20 2023-12-19 Antecip Bioventures Ii Llc Combination of dextromethorphan and bupropion for treating depression

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5350756A (en) 1991-06-17 1994-09-27 Smith Richard A Use of a cytochrome oxidase inhibitor to increase the cough-suppressing activity of dextromorphan
JP2001527554A (ja) * 1997-05-07 2001-12-25 アルゴス ファーマシューティカル コーポレーション 抗うつ薬とnmdaレセプター拮抗薬とを組み合わせる神経障害痛の治療用組成物及び治療方法
US6207674B1 (en) * 1999-12-22 2001-03-27 Richard A. Smith Dextromethorphan and oxidase inhibitor for weaning patients from narcotics and anti-depressants
US6780871B2 (en) * 2001-01-29 2004-08-24 Albany Medical College Methods and compositions for treating addiction disorders
TWI326214B (en) * 2002-07-17 2010-06-21 Avanir Pharmaceuticals Inc Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of neurological disorders
AU2007212586A1 (en) * 2006-02-03 2007-08-16 Avanir Pharmaceuticals Pharmaceutical compositions for treating depression, anxiety and neurodegenerative disorders
WO2009006194A1 (en) * 2007-06-28 2009-01-08 Avanir Pharmaceuticals Pharmaceutical compositions for the treatment of involuntary emotional expression disorder
WO2012118562A1 (en) * 2011-03-02 2012-09-07 Rhine Pharmaceuticals, Llc Compositions and methods for treating depression, adhd and other central nervous system disorders employing novel bupropion compounds, and methods for production and use of novel bupropion compounds and formulations
US20130274282A1 (en) * 2012-04-16 2013-10-17 Herriot Tabuteau Compositions and methods comprising celecoxib or related compounds and dextromethorphan
NZ758432A (en) * 2013-11-05 2021-07-30 Antecip Bioventures Ii Llc Compositions and methods comprising bupropion or related compounds and dextromethorphan

Also Published As

Publication number Publication date
CN110327338A (zh) 2019-10-15
JP2020023543A (ja) 2020-02-13
JP2016535786A (ja) 2016-11-17
AU2019275593A1 (en) 2020-01-02
KR102603013B1 (ko) 2023-11-15
EP3065742A1 (en) 2016-09-14
KR20220054909A (ko) 2022-05-03
EP3981404A1 (en) 2022-04-13
MX2016005867A (es) 2016-07-15
IL283760B1 (en) 2023-01-01
AU2019275593B2 (en) 2021-01-28
IL245504B (en) 2021-06-30
AU2023203438A1 (en) 2023-07-06
KR20160070158A (ko) 2016-06-17
MY179696A (en) 2020-11-11
CN110279682A (zh) 2019-09-27
CA2929415A1 (en) 2015-05-14
EP3065742A4 (en) 2017-04-05
IL298972A (en) 2023-02-01
AU2019236614B2 (en) 2021-07-15
CA3154845C (en) 2023-02-28
AU2018203638B2 (en) 2019-07-18
JP2023129646A (ja) 2023-09-14
SG10201810888XA (en) 2019-01-30
KR20230148385A (ko) 2023-10-24
AU2021202497B2 (en) 2023-03-02
KR20210068157A (ko) 2021-06-08
MX2020004075A (es) 2021-12-10
NZ758431A (en) 2021-07-30
NZ758425A (en) 2021-07-30
SG11201603391XA (en) 2016-05-30
JP2021169527A (ja) 2021-10-28
EP3981403A1 (en) 2022-04-13
CN110251517A (zh) 2019-09-20
IL283760A (en) 2021-07-29
AU2018203638A1 (en) 2018-06-14
IL283760B2 (en) 2023-05-01
NZ758428A (en) 2021-07-30
KR102264179B1 (ko) 2021-06-11
NZ719892A (en) 2021-07-30
SG10201911816XA (en) 2020-01-30
CN113750098A (zh) 2021-12-07
IL245504A0 (en) 2016-06-30
AU2019236614C1 (en) 2021-10-14
NZ758432A (en) 2021-07-30
AU2014346807A1 (en) 2016-05-19
AU2014346807B2 (en) 2018-03-22
AU2018203638C1 (en) 2019-10-24
WO2015069809A1 (en) 2015-05-14
CN113797205A (zh) 2021-12-17
MX2021015234A (es) 2022-05-26
AU2021202497A1 (en) 2021-05-27
CA3175703A1 (en) 2015-05-14
SG10201911808QA (en) 2020-01-30
CN106163522A (zh) 2016-11-23
CN113750099A (zh) 2021-12-07
JP6605485B2 (ja) 2019-11-13
JP6927601B2 (ja) 2021-09-01
CA2929415C (en) 2023-01-03
CA3154845A1 (en) 2015-05-14
AU2019236614A1 (en) 2019-10-17

Similar Documents

Publication Publication Date Title
MX373330B (es) Composiciones y métodos que comprenden bupropion o compuestos relacionados y dextrometorfano.
PH12016500511A1 (en) Selective grp94 inhibitors and uses thereof
BR112016008468A2 (pt) Composto de fórmula, composição farmacêutica, composto, uso de um composto e método para o tratamento ou melhora de câncer
EA201600204A1 (ru) Производные хиназолина, фармацевтическая композиция на их основе и их применение для профилактики или лечения опухоли
NI201600071A (es) Compuestos de inhibidor de autotaxina
EA201690223A1 (ru) Ингибиторы фактора в комплемента на основе производных пиперидинилиндола и их применение
UA117451C2 (uk) Терапевтично активні сполуки і способи їх застосування
EA201290919A1 (ru) Индазольные соединения и их применение
EA201690753A1 (ru) Комбинации ингибиторов гистондеацетилазы и иммуномодулирующих лекарственных средств
EA201591327A1 (ru) Замещенные пирролопиримидиновые соединения, их композиции и способы лечения с использованием таких соединений
MX375254B (es) Una composición antimicrobiana farmacéutica o veterinaria intramamaria que comprende un poliéter ionóforo, o un uso de la misma para tratar mastitis.
BR112015029462A8 (pt) Inibidores de quinase
MX2016004741A (es) Composicion farmaceutica que comprende un antagonista de trpa1 y un agente analgesico.
EA201690386A1 (ru) Соединения и композиции в качестве ингибиторов mek
EA201690039A1 (ru) Ингибиторы rorc2 и способы их применения
EA201692481A1 (ru) Комбинация, содержащая глюкокортикоид и edo-s101
CR20160290A (es) Inhibidores tetracíclicos de autotaxina
EA201591507A1 (ru) Лечение рассеянного склероза лахинимодом
MX2022015141A (es) Composiciones y metodos de uso de un compuesto de control de inapetencia.
MX2022014763A (es) Composiciones de grapiprant y metodos para usar las mismas.
MX2015012455A (es) Metodo para el tratamiento de la enfermedad de higado graso.
EA201491581A1 (ru) Везикулярные композиции
EA201690445A1 (ru) Лечение рака
EA201690446A1 (ru) Лечение множественной миеломы
UA113859C2 (xx) Похідні спіротієнопіранпіперидину як антагоністи рецептора orl-1 для їх застосування при лікуванні алкогольної залежності та зловживання алкоголем

Legal Events

Date Code Title Description
FG Grant or registration