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SG10201911816XA - Compositions and methods comprising bupropion or related compounds and dextromethorphan - Google Patents

Compositions and methods comprising bupropion or related compounds and dextromethorphan

Info

Publication number
SG10201911816XA
SG10201911816XA SG10201911816XA SG10201911816XA SG10201911816XA SG 10201911816X A SG10201911816X A SG 10201911816XA SG 10201911816X A SG10201911816X A SG 10201911816XA SG 10201911816X A SG10201911816X A SG 10201911816XA SG 10201911816X A SG10201911816X A SG 10201911816XA
Authority
SG
Singapore
Prior art keywords
dextromethorphan
bupropion
compositions
methods
related compounds
Prior art date
Application number
SG10201911816XA
Other languages
English (en)
Inventor
Herriot Tabuteau
Original Assignee
Antecip Bioventures Ii Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antecip Bioventures Ii Llc filed Critical Antecip Bioventures Ii Llc
Publication of SG10201911816XA publication Critical patent/SG10201911816XA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG10201911816XA 2013-11-05 2014-11-05 Compositions and methods comprising bupropion or related compounds and dextromethorphan SG10201911816XA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361900354P 2013-11-05 2013-11-05

Publications (1)

Publication Number Publication Date
SG10201911816XA true SG10201911816XA (en) 2020-01-30

Family

ID=53042051

Family Applications (4)

Application Number Title Priority Date Filing Date
SG11201603391XA SG11201603391XA (en) 2013-11-05 2014-11-05 Compositions and methods comprising bupropion or related compounds and dextromethorphan
SG10201810888XA SG10201810888XA (en) 2013-11-05 2014-11-05 Compositions and methods comprising bupropion or related compounds and dextromethorphan
SG10201911816XA SG10201911816XA (en) 2013-11-05 2014-11-05 Compositions and methods comprising bupropion or related compounds and dextromethorphan
SG10201911808QA SG10201911808QA (en) 2013-11-05 2014-11-05 Compositions and methods comprising bupropion or related compounds and dextromethorphan

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SG11201603391XA SG11201603391XA (en) 2013-11-05 2014-11-05 Compositions and methods comprising bupropion or related compounds and dextromethorphan
SG10201810888XA SG10201810888XA (en) 2013-11-05 2014-11-05 Compositions and methods comprising bupropion or related compounds and dextromethorphan

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201911808QA SG10201911808QA (en) 2013-11-05 2014-11-05 Compositions and methods comprising bupropion or related compounds and dextromethorphan

Country Status (12)

Country Link
EP (3) EP3981403A1 (es)
JP (4) JP6605485B2 (es)
KR (4) KR20230148385A (es)
CN (7) CN110251517A (es)
AU (6) AU2014346807B2 (es)
CA (3) CA3154845C (es)
IL (3) IL298972A (es)
MX (3) MX388666B (es)
MY (1) MY179696A (es)
NZ (5) NZ758432A (es)
SG (4) SG11201603391XA (es)
WO (1) WO2015069809A1 (es)

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US11191739B2 (en) 2013-11-05 2021-12-07 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11253492B2 (en) 2013-11-05 2022-02-22 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11253491B2 (en) 2013-11-05 2022-02-22 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11147808B2 (en) 2013-11-05 2021-10-19 Antecip Bioventures Ii Llc Method of decreasing the fluctuation index of dextromethorphan
US11571417B2 (en) 2013-11-05 2023-02-07 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11534414B2 (en) 2013-11-05 2022-12-27 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11311534B2 (en) 2013-11-05 2022-04-26 Antecip Bio Ventures Ii Llc Bupropion as a modulator of drug activity
US11541048B2 (en) 2013-11-05 2023-01-03 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11382874B2 (en) 2013-11-05 2022-07-12 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11291665B2 (en) 2013-11-05 2022-04-05 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11273133B2 (en) 2013-11-05 2022-03-15 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11590124B2 (en) 2013-11-05 2023-02-28 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11207281B2 (en) 2013-11-05 2021-12-28 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11285118B2 (en) 2013-11-05 2022-03-29 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
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US11364233B2 (en) 2013-11-05 2022-06-21 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11617747B2 (en) 2013-11-05 2023-04-04 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
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US11617728B2 (en) 2013-11-05 2023-04-04 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
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US11197839B2 (en) 2013-11-05 2021-12-14 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US20200338022A1 (en) 2019-01-07 2020-10-29 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11576909B2 (en) 2013-11-05 2023-02-14 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11524007B2 (en) 2013-11-05 2022-12-13 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11298352B2 (en) 2013-11-05 2022-04-12 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11439636B1 (en) 2013-11-05 2022-09-13 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11571399B2 (en) 2013-11-05 2023-02-07 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11596627B2 (en) 2013-11-05 2023-03-07 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11426401B2 (en) 2013-11-05 2022-08-30 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
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KR20230148385A (ko) * 2013-11-05 2023-10-24 안테씨프 바이오벤쳐스 투 엘엘씨 부프로피온 또는 관련 화합물과 덱스트로메토르판을 포함하는 조성물 및 방법
US11478468B2 (en) 2013-11-05 2022-10-25 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US20220233470A1 (en) 2013-11-05 2022-07-28 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11576877B2 (en) 2013-11-05 2023-02-14 Antecip Bioventures Ii Llc Bupropion as modulator of drug activity
US12194006B2 (en) 2013-11-05 2025-01-14 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
TWI869633B (zh) * 2014-09-14 2025-01-11 美商阿瓦尼爾製藥股份有限公司 用於治療失智症中躁動行為之包含右旋美索芬(dextromethorphan)化合物及奎尼丁(quinidine)的藥學組成物
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CN115697314A (zh) * 2020-03-30 2023-02-03 安泰赛普生物风投二代有限责任公司 安非他酮和右美沙芬组合用于治疗神经病症的用途
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JP2023553393A (ja) 2020-12-01 2023-12-21 アンテシップ バイオベンチャーズ トゥー エルエルシー うつ病患者の自殺リスク低減のためのブプロピオンおよびデキストロメトルファン
KR20230131927A (ko) * 2021-01-18 2023-09-14 안테씨프 바이오벤쳐스 투 엘엘씨 신경 정신 질환에 대한 항우울제와 덱스트로메토르판의조합
CN112999350A (zh) * 2021-02-23 2021-06-22 北京斯利安药业有限公司 一种药物组合物、复方制剂及其制备方法与应用
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CN106163522A (zh) 2016-11-23
NZ758428A (en) 2021-07-30
NZ758431A (en) 2021-07-30
MX2016005867A (es) 2016-07-15
JP6927601B2 (ja) 2021-09-01
AU2023203438A1 (en) 2023-07-06
MX388666B (es) 2025-03-20
JP2023129646A (ja) 2023-09-14
JP2021169527A (ja) 2021-10-28
KR20230148385A (ko) 2023-10-24
NZ719892A (en) 2021-07-30
CN113797205A (zh) 2021-12-17
JP2016535786A (ja) 2016-11-17
CN110279682A (zh) 2019-09-27
AU2019275593B2 (en) 2021-01-28
CN110327338A (zh) 2019-10-15
NZ758432A (en) 2021-07-30
KR102603013B1 (ko) 2023-11-15
CA3154845A1 (en) 2015-05-14
AU2019275593A1 (en) 2020-01-02
KR20160070158A (ko) 2016-06-17
MX2020004075A (es) 2021-12-10
KR20220054909A (ko) 2022-05-03
KR102264179B1 (ko) 2021-06-11
CN113750098A (zh) 2021-12-07
JP2020023543A (ja) 2020-02-13
WO2015069809A1 (en) 2015-05-14
AU2018203638B2 (en) 2019-07-18
EP3981403A1 (en) 2022-04-13
NZ758425A (en) 2021-07-30
SG10201911808QA (en) 2020-01-30
KR20210068157A (ko) 2021-06-08
MX373330B (es) 2020-05-04
CA3154845C (en) 2023-02-28
IL245504B (en) 2021-06-30
SG10201810888XA (en) 2019-01-30
EP3065742A1 (en) 2016-09-14
MX2021015234A (es) 2022-05-26
CN113750099A (zh) 2021-12-07
AU2021202497A1 (en) 2021-05-27
AU2019236614B2 (en) 2021-07-15
AU2019236614C1 (en) 2021-10-14
IL283760B1 (en) 2023-01-01
AU2018203638A1 (en) 2018-06-14
CA2929415A1 (en) 2015-05-14
AU2014346807A1 (en) 2016-05-19
CA2929415C (en) 2023-01-03
EP3065742A4 (en) 2017-04-05
AU2021202497B2 (en) 2023-03-02
IL245504A0 (en) 2016-06-30
IL283760A (en) 2021-07-29
IL283760B2 (en) 2023-05-01
MY179696A (en) 2020-11-11
CN110251517A (zh) 2019-09-20
JP6605485B2 (ja) 2019-11-13
AU2018203638C1 (en) 2019-10-24
SG11201603391XA (en) 2016-05-30
AU2014346807B2 (en) 2018-03-22
AU2019236614A1 (en) 2019-10-17
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EP3981404A1 (en) 2022-04-13
IL298972A (en) 2023-02-01

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