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MX2023013975A - Derivado de fenil urea. - Google Patents

Derivado de fenil urea.

Info

Publication number
MX2023013975A
MX2023013975A MX2023013975A MX2023013975A MX2023013975A MX 2023013975 A MX2023013975 A MX 2023013975A MX 2023013975 A MX2023013975 A MX 2023013975A MX 2023013975 A MX2023013975 A MX 2023013975A MX 2023013975 A MX2023013975 A MX 2023013975A
Authority
MX
Mexico
Prior art keywords
agent
urea derivative
invention pertains
phenyl urea
present
Prior art date
Application number
MX2023013975A
Other languages
English (en)
Inventor
Daisuke Tanaka
Shunichiro UESUGI
Eiji Ideue
Masafumi Komiya
Shoukou Lee
Yuta Funakoshi
Original Assignee
Sumitomo Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Pharma Co Ltd filed Critical Sumitomo Pharma Co Ltd
Publication of MX2023013975A publication Critical patent/MX2023013975A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
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Abstract

La presente invención se refiere a un medicamento para tratar o prevenir una enfermedad relacionada con receptor de orexina, especialmente receptor de orexina tipo 2, que comprende un nuevo compuesto que tiene una estructura de urea o una sal farmacéuticamente aceptable de la misma como un ingrediente activo; en más detalle, la presente invención se refiere a un medicamento para tratar o prevenir una enfermedad tal como narcolepsia, hipersomnia idiopática, hipersomnia, síndrome de apnea del sueño.
MX2023013975A 2021-05-26 2022-05-26 Derivado de fenil urea. MX2023013975A (es)

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EP4512807A1 (en) * 2022-04-22 2025-02-26 Sumitomo Pharma Co., Ltd. Bicycloamine carboxamide derivative
WO2025010314A1 (en) * 2023-07-05 2025-01-09 Vertex Pharmaceuticals Incorporated Urea-containing agonists of orexin receptor type 2
WO2025010311A1 (en) * 2023-07-05 2025-01-09 Vertex Pharmaceuticals Incorporated Urea-containing agonists of orexin receptor type 2
WO2025124698A1 (en) 2023-12-12 2025-06-19 Idorsia Pharmaceuticals Ltd Aryl sulfone and sulfanone derivatives as orexin receptor modulators
WO2025132542A1 (en) 2023-12-19 2025-06-26 Idorsia Pharmaceuticals Ltd Macrocyclic orexin agonists

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BR9917038A (pt) * 1998-12-18 2002-04-02 Du Pont Pharm Co Composto, composição farmacêutica, método de modulação da atividade receptora de quimocinas, método de tratamento ou prevenção de doenças inflamatórias, método de tratamento ou prevenção de asma e método de tratamento ou prevenção de disfunções inflamatórias
WO2000035877A1 (en) * 1998-12-18 2000-06-22 Du Pont Pharmaceuticals Company Heterocyclic piperidines as modulators of chemokine receptor activity
DE60132611T2 (de) * 2000-10-27 2009-02-19 Ortho-Mcneil Pharmaceutical, Inc. Substituierte benzimidazol-2-one als vasopressin receptor antagonisten und neuropeptide y modulatoren
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