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MX2023005341A - Proceso de preparación de 2-hidroxi-6-((2-(1-isopropil-1h-pirazol- 5-il)piridin-3-il)metoxi)benzaldehído. - Google Patents

Proceso de preparación de 2-hidroxi-6-((2-(1-isopropil-1h-pirazol- 5-il)piridin-3-il)metoxi)benzaldehído.

Info

Publication number
MX2023005341A
MX2023005341A MX2023005341A MX2023005341A MX2023005341A MX 2023005341 A MX2023005341 A MX 2023005341A MX 2023005341 A MX2023005341 A MX 2023005341A MX 2023005341 A MX2023005341 A MX 2023005341A MX 2023005341 A MX2023005341 A MX 2023005341A
Authority
MX
Mexico
Prior art keywords
pyrazol
benzaldehyde
pyridin
methoxy
isopropyl
Prior art date
Application number
MX2023005341A
Other languages
English (en)
Inventor
Fang Wang
Xiang Wang
Morin Mae Frick
Youqian Deng
Original Assignee
Global Blood Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Global Blood Therapeutics Inc filed Critical Global Blood Therapeutics Inc
Publication of MX2023005341A publication Critical patent/MX2023005341A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

La presente descripción se refiere a procesos para preparar un compuesto de la Fórmula (I)(ver formula).
MX2023005341A 2020-11-06 2021-11-05 Proceso de preparación de 2-hidroxi-6-((2-(1-isopropil-1h-pirazol- 5-il)piridin-3-il)metoxi)benzaldehído. MX2023005341A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063110826P 2020-11-06 2020-11-06
US202163237780P 2021-08-27 2021-08-27
PCT/US2021/058324 WO2022099064A2 (en) 2020-11-06 2021-11-05 Process for preparation of 2-hydroxy-6-((2-(1-isopropyl- 1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde

Publications (1)

Publication Number Publication Date
MX2023005341A true MX2023005341A (es) 2023-08-02

Family

ID=78820157

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023005341A MX2023005341A (es) 2020-11-06 2021-11-05 Proceso de preparación de 2-hidroxi-6-((2-(1-isopropil-1h-pirazol- 5-il)piridin-3-il)metoxi)benzaldehído.

Country Status (9)

Country Link
US (3) US20220144800A1 (es)
EP (1) EP4240729A2 (es)
JP (1) JP2023548293A (es)
AU (1) AU2021376284B2 (es)
CA (1) CA3200662A1 (es)
IL (1) IL302652A (es)
MX (1) MX2023005341A (es)
TW (1) TW202233589A (es)
WO (1) WO2022099064A2 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023248174A1 (en) * 2022-06-22 2023-12-28 Hetero Labs Limited An improved process for preparation of voxelotor

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2797416T3 (en) 2011-12-28 2017-10-30 Global Blood Therapeutics Inc SUBSTITUTED BENZALDEHYD COMPOUNDS AND METHODS OF USING THEM IN INCREASED TISSUE OXIDATION
ES2890077T3 (es) * 2013-03-15 2022-01-17 Global Blood Therapeutics Inc Compuestos y usos de los mismos para la modulación de la hemoglobina
FI3102208T4 (fi) 2014-02-07 2024-09-23 Global Blood Therapeutics Inc 2-hydroksi-6-((2-(1-isopropyyli-1h-pyratsol-5-yyli)pyridin-3-yyli)metoksi)bentsaldehydin vapaan emäksen kiteinen polymorfi
TWI825524B (zh) * 2016-05-12 2023-12-11 美商全球血液治療公司 用於合成2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)-吡啶-3-基)甲氧基)苯甲醛之方法
WO2017218960A1 (en) * 2016-06-17 2017-12-21 Fronthera U.S. Pharmaceuticals Llc Hemoglobin modifier compounds and uses thereof
CN113226506B (zh) 2018-12-19 2023-05-12 格礼卡姆股份公司 寡糖的分离
BR112021012311A2 (pt) 2018-12-21 2021-09-08 Crystal Pharma, S.A.U. Uso de um composto intermediário, processo para preparar voxelotor e composto intermediário

Also Published As

Publication number Publication date
WO2022099064A3 (en) 2022-06-30
TW202233589A (zh) 2022-09-01
JP2023548293A (ja) 2023-11-16
CA3200662A1 (en) 2022-05-12
AU2021376284B2 (en) 2024-10-03
WO2022099064A2 (en) 2022-05-12
AU2021376284A8 (en) 2023-06-22
US20220144800A1 (en) 2022-05-12
IL302652A (en) 2023-07-01
US20230174504A1 (en) 2023-06-08
US20220324833A1 (en) 2022-10-13
EP4240729A2 (en) 2023-09-13
AU2021376284A1 (en) 2023-06-15

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