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MX2023000211A - Composiciones de vacuna que tienen estabilidad e inmunogenicidad mejoradas. - Google Patents

Composiciones de vacuna que tienen estabilidad e inmunogenicidad mejoradas.

Info

Publication number
MX2023000211A
MX2023000211A MX2023000211A MX2023000211A MX2023000211A MX 2023000211 A MX2023000211 A MX 2023000211A MX 2023000211 A MX2023000211 A MX 2023000211A MX 2023000211 A MX2023000211 A MX 2023000211A MX 2023000211 A MX2023000211 A MX 2023000211A
Authority
MX
Mexico
Prior art keywords
improved stability
immunogenicity
vaccine compositions
nanoparticles
vaccines
Prior art date
Application number
MX2023000211A
Other languages
English (en)
Inventor
Ye Liu
Gale Smith
Michael Massare
Erica Shane
Cynthia Oliver
Sarathi Boddapati
Gregory Glenn
Jing - Hui TIAN
Original Assignee
Novavax Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novavax Inc filed Critical Novavax Inc
Publication of MX2023000211A publication Critical patent/MX2023000211A/es

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
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    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
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    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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Abstract

En la presente se divulgan nanopartículas adecuadas para uso en vacunas. Las nanopartículas presentan antígenos de patógenos que rodean y están asociados con un núcleo de detergente, lo que genera estabilidad mejorada y buena inmunogenicidad. También se revelan las dosis, las formulaciones y los métodos para preparar las vacunas y las nanopartículas.
MX2023000211A 2015-09-03 2018-03-02 Composiciones de vacuna que tienen estabilidad e inmunogenicidad mejoradas. MX2023000211A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562213947P 2015-09-03 2015-09-03
US201562255786P 2015-11-16 2015-11-16
US201662309216P 2016-03-16 2016-03-16
US201662350973P 2016-06-16 2016-06-16

Publications (1)

Publication Number Publication Date
MX2023000211A true MX2023000211A (es) 2023-02-09

Family

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Family Applications (3)

Application Number Title Priority Date Filing Date
MX2018002728A MX2018002728A (es) 2015-09-03 2016-09-06 Composiciones de vacuna que tienen estabilidad e inmunogenicidad mejoradas.
MX2020011717A MX2020011717A (es) 2015-09-03 2018-03-02 Composiciones de vacuna que tienen estabilidad e inmunogenicidad mejoradas.
MX2023000211A MX2023000211A (es) 2015-09-03 2018-03-02 Composiciones de vacuna que tienen estabilidad e inmunogenicidad mejoradas.

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MX2018002728A MX2018002728A (es) 2015-09-03 2016-09-06 Composiciones de vacuna que tienen estabilidad e inmunogenicidad mejoradas.
MX2020011717A MX2020011717A (es) 2015-09-03 2018-03-02 Composiciones de vacuna que tienen estabilidad e inmunogenicidad mejoradas.

Country Status (14)

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US (4) US10426829B2 (es)
EP (2) EP4494650A3 (es)
JP (4) JP6670374B2 (es)
KR (3) KR102758377B1 (es)
CN (4) CN108697790B (es)
AU (2) AU2016315478B2 (es)
BR (1) BR112018004242A2 (es)
CA (1) CA2996007A1 (es)
ES (1) ES3015079T3 (es)
IL (3) IL303336B1 (es)
MX (3) MX2018002728A (es)
RU (1) RU2730625C2 (es)
SG (1) SG10201913145SA (es)
WO (1) WO2017041100A2 (es)

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