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MX2022010521A - Metodo para producir linfocitos citoliticos naturales a partir de celulas madre pluripotentes. - Google Patents

Metodo para producir linfocitos citoliticos naturales a partir de celulas madre pluripotentes.

Info

Publication number
MX2022010521A
MX2022010521A MX2022010521A MX2022010521A MX2022010521A MX 2022010521 A MX2022010521 A MX 2022010521A MX 2022010521 A MX2022010521 A MX 2022010521A MX 2022010521 A MX2022010521 A MX 2022010521A MX 2022010521 A MX2022010521 A MX 2022010521A
Authority
MX
Mexico
Prior art keywords
cells
natural killer
pluripotent stem
producing natural
stem cells
Prior art date
Application number
MX2022010521A
Other languages
English (en)
Inventor
Lan Cao
Hui-Hsin Chang
Jianxin Hu
Xi Shi
Yu Qian
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of MX2022010521A publication Critical patent/MX2022010521A/es

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0646—Natural killers cells [NK], NKT cells
    • C—CHEMISTRY; METALLURGY
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
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Abstract

La presente descripción proporciona, entre otras cosas, un método para producir eficazmente linfocitos citolíticos naturales a partir de células pluripotentes inducidas. El método incluye los pasos de: (I) cultivar células madre pluripotentes en un medio de cultivo para producir células inmunitarias CD56+/CD3-.
MX2022010521A 2020-02-28 2021-02-26 Metodo para producir linfocitos citoliticos naturales a partir de celulas madre pluripotentes. MX2022010521A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202062983511P 2020-02-28 2020-02-28
PCT/US2021/019917 WO2021174004A1 (en) 2020-02-28 2021-02-26 Method for producing natural killer cells from pluripotent stem cells

Publications (1)

Publication Number Publication Date
MX2022010521A true MX2022010521A (es) 2022-09-19

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MX2022010521A MX2022010521A (es) 2020-02-28 2021-02-26 Metodo para producir linfocitos citoliticos naturales a partir de celulas madre pluripotentes.

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US (1) US12351824B2 (es)
EP (1) EP4110904A1 (es)
JP (1) JP2023516632A (es)
KR (1) KR20220148174A (es)
CN (1) CN115427555A (es)
AR (1) AR121455A1 (es)
AU (1) AU2021225952A1 (es)
BR (1) BR112022017216A2 (es)
CA (1) CA3169617A1 (es)
CO (1) CO2022011682A2 (es)
IL (1) IL295964A (es)
MX (1) MX2022010521A (es)
WO (1) WO2021174004A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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US11473060B2 (en) 2020-12-30 2022-10-18 Crispr Therapeutics Ag Compositions and methods for differentiating stem cells into NK cells
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