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MX2022001769A - Construcciones de vesícula extracelular-oligonucleótido antisentido (aso) que se dirigen a la proteína beta de unión al potenciador ccaat (cebp)/beta. - Google Patents

Construcciones de vesícula extracelular-oligonucleótido antisentido (aso) que se dirigen a la proteína beta de unión al potenciador ccaat (cebp)/beta.

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Publication number
MX2022001769A
MX2022001769A MX2022001769A MX2022001769A MX2022001769A MX 2022001769 A MX2022001769 A MX 2022001769A MX 2022001769 A MX2022001769 A MX 2022001769A MX 2022001769 A MX2022001769 A MX 2022001769A MX 2022001769 A MX2022001769 A MX 2022001769A
Authority
MX
Mexico
Prior art keywords
aso
cebp
beta
extracellular vesicle
constructs targeting
Prior art date
Application number
MX2022001769A
Other languages
English (en)
Inventor
Sriram Sathyanarayanan
Ajay Verma
Dalia Burzyn
Sushrut Kamerkar
Adam T Boutin
Wendy Broom
Original Assignee
Codiak Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Codiak Biosciences Inc filed Critical Codiak Biosciences Inc
Publication of MX2022001769A publication Critical patent/MX2022001769A/es

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Abstract

La presente descripción se relaciona con vesículas extracelulares, p. ej., exosomas, que comprenden un oligonucleótido antisentido (ASO), en donde el ASO comprende una secuencia de nucleótidos contiguos de 10 a 30 nucleótidos de longitud que es complementaria a una secuencia de ácido nucleico dentro de un transcrito CEBP/. En la presente también se proporcionan métodos para producir los exosomas y métodos para usar los exosomas para tratar y/o prevenir enfermedades o trastornos.
MX2022001769A 2019-08-14 2020-08-14 Construcciones de vesícula extracelular-oligonucleótido antisentido (aso) que se dirigen a la proteína beta de unión al potenciador ccaat (cebp)/beta. MX2022001769A (es)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201962886930P 2019-08-14 2019-08-14
US201962900136P 2019-09-13 2019-09-13
US201962936220P 2019-11-15 2019-11-15
US201962944204P 2019-12-05 2019-12-05
US202062989540P 2020-03-13 2020-03-13
US202063023065P 2020-05-11 2020-05-11
US202063035357P 2020-06-05 2020-06-05
PCT/US2020/046563 WO2021030780A1 (en) 2019-08-14 2020-08-14 Extracellular vesicle-aso constructs targeting cebp/beta

Publications (1)

Publication Number Publication Date
MX2022001769A true MX2022001769A (es) 2022-06-09

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MX2022001769A MX2022001769A (es) 2019-08-14 2020-08-14 Construcciones de vesícula extracelular-oligonucleótido antisentido (aso) que se dirigen a la proteína beta de unión al potenciador ccaat (cebp)/beta.

Country Status (11)

Country Link
US (1) US20230002764A1 (es)
EP (1) EP4013878A1 (es)
JP (1) JP2022544288A (es)
KR (1) KR20220070432A (es)
CN (1) CN114729366A (es)
AU (1) AU2020330133A1 (es)
BR (1) BR112022002690A2 (es)
CA (1) CA3147369A1 (es)
IL (1) IL290497A (es)
MX (1) MX2022001769A (es)
WO (1) WO2021030780A1 (es)

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